Page last updated: 2024-11-01

ondansetron and Abnormalities, Congenital

ondansetron has been researched along with Abnormalities, Congenital in 8 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Research Excerpts

ExcerptRelevanceReference
"To study the association between ondansetron exposure during pregnancy and the risks of spontaneous abortion, stillbirth, and major congenital malformations."9.12Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort. ( Dahl, M; Dormuth, CR; Filion, KB; Fisher, A; Lu, X; Ma, Z; Moriello, C; Paterson, JM; Platt, RW; Raymond, CB; Reynier, P; Suissa, S; Winquist, B; Wu, F; Zhang, J, 2021)
"Ondansetron, not approved for use in pregnancy, is increasingly being prescribed for nausea and vomiting in pregnancy and hyperemesis gravidarum."8.98Ondansetron in Pregnancy and the Risk of Congenital Malformations: A Systematic Review. ( Campbell, S; Chari, R; Lavecchia, M; Ross, S, 2018)
"This is an analysis of fetal outcome in pregnancies exposed to ondansetron to treat Hyperemesis Gravidarum (HG)."7.83Ondansetron in pregnancy and risk of adverse fetal outcomes in the United States. ( Fejzo, MS; MacGibbon, KW; Mullin, PM, 2016)
"Our study did not detect any adverse outcomes from the use of ondansetron in pregnancy but could not conclude that ondansetron is safe to use in pregnancy."7.79Off-label use of ondansetron in pregnancy in Western Australia. ( Bower, C; Colvin, L; Gill, AW; Slack-Smith, L; Stanley, FJ, 2013)
"To study the association between ondansetron exposure during pregnancy and the risks of spontaneous abortion, stillbirth, and major congenital malformations."5.12Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort. ( Dahl, M; Dormuth, CR; Filion, KB; Fisher, A; Lu, X; Ma, Z; Moriello, C; Paterson, JM; Platt, RW; Raymond, CB; Reynier, P; Suissa, S; Winquist, B; Wu, F; Zhang, J, 2021)
"Ondansetron, not approved for use in pregnancy, is increasingly being prescribed for nausea and vomiting in pregnancy and hyperemesis gravidarum."4.98Ondansetron in Pregnancy and the Risk of Congenital Malformations: A Systematic Review. ( Campbell, S; Chari, R; Lavecchia, M; Ross, S, 2018)
"This is an analysis of fetal outcome in pregnancies exposed to ondansetron to treat Hyperemesis Gravidarum (HG)."3.83Ondansetron in pregnancy and risk of adverse fetal outcomes in the United States. ( Fejzo, MS; MacGibbon, KW; Mullin, PM, 2016)
"Our study did not detect any adverse outcomes from the use of ondansetron in pregnancy but could not conclude that ondansetron is safe to use in pregnancy."3.79Off-label use of ondansetron in pregnancy in Western Australia. ( Bower, C; Colvin, L; Gill, AW; Slack-Smith, L; Stanley, FJ, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Kirby, RS2
Damkier, P1
Kaplan, YC1
Shechtman, S1
Diav-Citrin, O1
Cassina, M1
Weber-Schoendorfer, C1
Cleary, B1
Hodson, K1
Dormuth, CR1
Winquist, B1
Fisher, A1
Wu, F1
Reynier, P1
Suissa, S1
Dahl, M1
Ma, Z1
Lu, X1
Zhang, J1
Raymond, CB1
Filion, KB1
Platt, RW1
Moriello, C1
Paterson, JM1
Lavecchia, M1
Chari, R1
Campbell, S1
Ross, S1
Zambelli-Weiner, A1
Via, C1
Yuen, M1
Weiner, DJ1
Kiernan, E1
Jones, KL1
Colvin, L1
Gill, AW1
Slack-Smith, L1
Stanley, FJ1
Bower, C1
Fejzo, MS1
MacGibbon, KW1
Mullin, PM1

Reviews

3 reviews available for ondansetron and Abnormalities, Congenital

ArticleYear
Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort.
    JAMA network open, 2021, 04-01, Volume: 4, Issue:4

    Topics: Abortion, Spontaneous; Adult; Antiemetics; Canada; Cohort Studies; Congenital Abnormalities; Databas

2021
Ondansetron in Pregnancy and the Risk of Congenital Malformations: A Systematic Review.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2018, Volume: 40, Issue:7

    Topics: Antiemetics; Congenital Abnormalities; Female; Humans; Hyperemesis Gravidarum; Ondansetron; Pregnanc

2018
Medications that Cause Fetal Anomalies and Possible Prevention Strategies.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Analg

2019

Other Studies

5 other studies available for ondansetron and Abnormalities, Congenital

ArticleYear
Ondansetron should never be used in pregnancy.
    BJOG : an international journal of obstetrics and gynaecology, 2021, Volume: 128, Issue:1

    Topics: Antiemetics; Congenital Abnormalities; Female; Humans; Hyperemesis Gravidarum; Ondansetron; Pregnanc

2021
Ondansetron should never be used in pregnancy: Against: Ondansetron in pregnancy revisited.
    BJOG : an international journal of obstetrics and gynaecology, 2021, Volume: 128, Issue:1

    Topics: Antiemetics; Congenital Abnormalities; Female; Humans; Hyperemesis Gravidarum; Ondansetron; Pregnanc

2021
First trimester ondansetron exposure and risk of structural birth defects.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 83

    Topics: Adult; Antiemetics; Congenital Abnormalities; Female; Humans; Male; Maternal-Fetal Exchange; Odds Ra

2019
Off-label use of ondansetron in pregnancy in Western Australia.
    BioMed research international, 2013, Volume: 2013

    Topics: Adult; Antiemetics; Congenital Abnormalities; Female; Humans; Hyperemesis Gravidarum; Infant, Newbor

2013
Ondansetron in pregnancy and risk of adverse fetal outcomes in the United States.
    Reproductive toxicology (Elmsford, N.Y.), 2016, Volume: 62

    Topics: Abortion, Spontaneous; Adolescent; Adult; Antiemetics; Child; Congenital Abnormalities; Female; Huma

2016