Page last updated: 2024-11-01

omeprazole and Weight Gain

omeprazole has been researched along with Weight Gain in 10 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"The impact of omeprazole (OM), a widely used over-the-counter proton pump inhibitor, on weight gain has not been extensively explored."7.85Weight gain in mice on a high caloric diet and chronically treated with omeprazole depends on sex and genetic background. ( Gillilland, MG; Merchant, JL; Saqui-Salces, M; Tsao, AC, 2017)
"The body weight gain was suppressed by omeprazole treatment."7.71Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats. ( Chen, D; Cui, GL; Syversen, U; Waldum, HL; Zhao, CM, 2001)
"The body weight gain was suppressed by omeprazole treatment."3.71Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats. ( Chen, D; Cui, GL; Syversen, U; Waldum, HL; Zhao, CM, 2001)
"The results indicate that omeprazole treatment in chickens leads not only to trophic effects in the acid-producing gastric mucosa (probably because of the ensuing hypergastrinemia), as reported earlier, but also to growth of the parathyroid glands (both hypertrophy and hyperplasia) and to bone loss without affecting blood calcium values."3.69Growth of the parathyroid glands in omeprazole-treated chickens. ( Gagnemo-Persson, R; Håkanson, R; Persson, P; Sundler, F, 1994)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saqui-Salces, M1
Tsao, AC1
Gillilland, MG1
Merchant, JL1
Cohen, H1
Tomasso, G1
Luisa Cafferata, M1
Zapata, C1
Sharma, P1
Armstrong, D1
Moraes-Filho, JP1
Blasco, C1
Corti, R1
Estape, G1
Leite Luna, L1
Ortuño, R1
Sakai, P1
Salis, G1
Taullard, D1
Trakal, E1
Valdovinos, M1
Vergara, M1
Gónzalez, O1
Yoshikawa, I1
Nagato, M1
Yamasaki, M1
Kume, K1
Otsuki, M1
Gagnemo-Persson, R1
Håkanson, R1
Sundler, F1
Persson, P1
Barraclough, M1
Taylor, CJ1
Hinrichsen, JP1
Neira, M1
Lopez, C1
Chiong, M1
Ocaranza, MP1
Gallardo, R1
Rutman, M1
Blamey, J1
Lavandero, S1
Srinivasan, R1
Minocha, A1
Støa-Birketvedt, G1
Løvhaug, N1
Vonen, B1
Florholmen, J1
Cui, GL1
Syversen, U1
Zhao, CM1
Chen, D1
Waldum, HL1
Raoul, JL1
Bretagne, JF1
Ropert, A1
Siproudhis, L1
Heresbach, D1
Gosselin, M1

Reviews

1 review available for omeprazole and Weight Gain

ArticleYear
Latin american consensus on gastroesophageal reflux disease: an update on therapy.
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:2

    Topics: Alginates; Antacids; Anti-Ulcer Agents; Cohort Studies; Consensus; Dose-Response Relationship, Drug;

2010

Other Studies

9 other studies available for omeprazole and Weight Gain

ArticleYear
Weight gain in mice on a high caloric diet and chronically treated with omeprazole depends on sex and genetic background.
    American journal of physiology. Gastrointestinal and liver physiology, 2017, 01-01, Volume: 312, Issue:1

    Topics: Adiposity; Animals; Diet, High-Fat; Energy Intake; Energy Metabolism; Feeding Behavior; Female; Gast

2017
Long-term treatment with proton pump inhibitor is associated with undesired weight gain.
    World journal of gastroenterology, 2009, Oct-14, Volume: 15, Issue:38

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Blood Pressure; Body Mass Index; Body Weight; Case-Co

2009
Growth of the parathyroid glands in omeprazole-treated chickens.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:6

    Topics: Animals; Bone Density; Chickens; DNA; Gastrins; Hyperplasia; Hypertrophy; Omeprazole; Organ Size; Pa

1994
Twenty-four hour ambulatory gastric and duodenal pH profiles in cystic fibrosis: effect of duodenal hyperacidity on pancreatic enzyme function and fat absorption.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 23, Issue:1

    Topics: Absorption; Acids; Child; Child, Preschool; Circadian Rhythm; Cystic Fibrosis; Dietary Fats; Duodenu

1996
Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 117, Issue:3

    Topics: Administration, Oral; Animal Feed; Animals; Anti-Ulcer Agents; Chickens; Dose-Response Relationship,

1997
Cure of Helicobacter pylori: a hidden curse?
    The American journal of gastroenterology, 1997, Volume: 92, Issue:12

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Duodenal Ulcer; Esop

1997
H2-receptor antagonist reduces food intake and weight gain in rats by non-gastric acid secretory mechanisms.
    Acta physiologica Scandinavica, 1997, Volume: 161, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Eating; Famotidine; Gastric Acid; Histamine H2 Antagonists;

1997
Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:10

    Topics: Age Factors; Animals; Anti-Ulcer Agents; Bone Diseases, Metabolic; Calcification, Physiologic; Enter

2001
Zollinger-Ellison syndrome, antisecretory treatment, and body weight.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:8

    Topics: Body Weight; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole

1992