Page last updated: 2024-11-01

omeprazole and Uremia

omeprazole has been researched along with Uremia in 5 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"High-risk peptic ulcer bleeding patients received endoscopic therapy with epinephrine (adrenaline) injection plus intravenous omeprazole (40 mg bolus followed by 40 mg infusion every 12 h) for 3 days."3.75Efficacy of an intravenous proton pump inhibitor after endoscopic therapy with epinephrine injection for peptic ulcer bleeding in patients with uraemia: a case-control study. ( Cheng, YT; Fang, CT; Huang, CH; Liao, PC; Lin, HJ; Tseng, GC; Tseng, GY; Wang, PC; Yang, HB, 2009)
" H2-receptors blocking drugs or gastric acidity buffers were withdrawn for 2 weeks, then omeprazole was administered for 4 weeks at a daily dosage of 20 mg."1.29Effects of omeprazole therapy on peptic disease and serum gastrin levels in hemodialysis patients. A preliminary study. ( Di Maggio, A; Franceschi, M; Loperfido, A; Montemurro, NE; Scatizzi, A, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, H1
Narayanan, R1
Hoffmann, M1
Surapaneni, S1
Tseng, GY1
Fang, CT1
Lin, HJ1
Yang, HB1
Tseng, GC1
Wang, PC1
Liao, PC1
Cheng, YT1
Huang, CH1
Seyyedmajidi, M1
Falaknazi, K1
Mirsattari, D1
Zojaji, H1
Roshani, M1
Lahmi, F1
Orimi, PG1
Hadizadeh, M1
Zali, M1
Montemurro, NE1
Di Maggio, A1
Loperfido, A1
Franceschi, M1
Scatizzi, A1
Nishitani, H1
Kim, CW1
Yamakawa, M1
Nishizawa, Y1
Morii, H1

Trials

1 trial available for omeprazole and Uremia

ArticleYear
Correlation between creatinine clearance and Helicobacter pylori infection eradication with sequential and triple therapeutic regimens: A randomised clinical trial.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2011, Volume: 12, Issue:3

    Topics: Amoxicillin; Anti-Bacterial Agents; Antibodies, Bacterial; Ciprofloxacin; Creatinine; Dose-Response

2011

Other Studies

4 other studies available for omeprazole and Uremia

ArticleYear
The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes.
    Drug metabolism letters, 2016, Volume: 10, Issue:3

    Topics: Adult; Aged; Cells, Cultured; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Female; Hep

2016
Efficacy of an intravenous proton pump inhibitor after endoscopic therapy with epinephrine injection for peptic ulcer bleeding in patients with uraemia: a case-control study.
    Alimentary pharmacology & therapeutics, 2009, Aug-15, Volume: 30, Issue:4

    Topics: Aged; Anti-Ulcer Agents; Blood Transfusion; Case-Control Studies; Drug Administration Schedule; Epin

2009
Effects of omeprazole therapy on peptic disease and serum gastrin levels in hemodialysis patients. A preliminary study.
    Clinical nephrology, 1993, Volume: 40, Issue:5

    Topics: Adult; Drug Administration Schedule; Female; Gastrins; Humans; Male; Middle Aged; Omeprazole; Peptic

1993
[Upper gastrointestinal complications in uremic patients with dialysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Benzamidines; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Guanidines; H

1992