Page last updated: 2024-11-01

omeprazole and Ulcer

omeprazole has been researched along with Ulcer in 47 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"To observe the effect of lansoprazole and omeprazole combined with antibiotics on gastric juice pH and inflammatory factors in elderly patients with Hp positive gastric ulcer."8.31Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer. ( Chen, B; Gao, N; Yan, S, 2023)
" However, a dose-dependent protection was observed only in the indomethacin-induced gastric ulceration model."7.78Methanol extract of Bauhinia purpurea leaf possesses anti-ulcer activity. ( Abdul Hisam, EE; Hasiah, AH; Norhafizah, M; Othman, F; Rofiee, MS; Vasudevan, M; Zakaria, ZA, 2012)
"The modulation of the cyclooxygenase-independent pathway by the green tea-derived polyphenol, epigallocatechin gallate (EGCG) during its healing action against indomethacin (IND)-induced stomach ulceration in mice was investigated."7.77Role of the COX-independent pathways in the ulcer-healing action of epigallocatechin gallate. ( Adhikary, B; Bandyopadhyay, SK; Chattopadhyay, S; Yadav, SK, 2011)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."7.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
"Twelve months after the reclassification of omeprazole the market growth of H2 antagonists sold from pharmacies was halted although there was no apparent impact on the prescription of ulcer-healing drugs."7.73Impact of the reclassification of omeprazole on the prescribing and sales of ulcer healing drugs. ( Dhippayom, T; Walker, R, 2006)
"Drug-induced esophagitis is an uncommon diagnosis in the pediatric population."5.56L-arginine-induced esophagitis, report of six cases. ( Casaubón-Garcín, PR; Ferreiro-Marin, A; González-Cruz, MÁ; Parra, PR, 2020)
"Such chronic ulcers have been associated with pain, stricture formation, and recurrent hemorrhage."5.28Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy. ( Gimson, A; Polson, R; Westaby, D; Williams, R, 1990)
"A combination package containing delayed-release capsules of the proton pump inhibitor lansoprazole (15 mg once daily) and tablets of the NSAID naproxen (375 or 500 mg twice daily) has been approved for reducing the risk of NSAID-associated gastric ulcers in NSAID-requiring patients with a documented history of gastric ulcer."4.82Delayed-release lansoprazole plus naproxen. ( Curran, MP; Wellington, K, 2004)
"Perhaps older drugs to treat ulcers, such as antacids, are just as effective as the newer drugs, but veterinarians have all but abandoned these drugs in favor of H2-receptor antagonists, sucralfate, and omeprazole."4.78Antiulcer therapy. ( Papich, MG, 1993)
"Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients."4.77Omeprazole in the short-term treatment of reflux oesophagitis. ( Jansen, JB; Lamers, CB, 1989)
"To observe the effect of lansoprazole and omeprazole combined with antibiotics on gastric juice pH and inflammatory factors in elderly patients with Hp positive gastric ulcer."4.31Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer. ( Chen, B; Gao, N; Yan, S, 2023)
"this study was aimed to see if propolis, ginseng in normal or nano form, and amygdalin might help in preventing the ulcerative effects of absolute ethanol."4.31Effectiveness of natural biomaterials in the protection and healing of experimentally induced gastric mucosa Ulcer in rats. ( Abdel-Gawad, DRI; El-Banna, AH; El-Banna, HA; El-Ela, FIA; Hassan, WH; Ibrahim, MA; Kamel, S; Moawad, UK, 2023)
" Male Sprague-Dawley (SD) rats were divided into six groups: normal control, ulcer control, omeprazole (30 mg/kg), and three ZJP groups (1."4.12Integrated serum pharmacochemistry and investigation of the anti-gastric ulcer effect of Zuojin pill in rats induced by ethanol. ( Che, X; Li, D; Ren, Y; Xu, Q; Yin, Y; Yu, C; Zhang, J; Zhao, J, 2022)
" However, a dose-dependent protection was observed only in the indomethacin-induced gastric ulceration model."3.78Methanol extract of Bauhinia purpurea leaf possesses anti-ulcer activity. ( Abdul Hisam, EE; Hasiah, AH; Norhafizah, M; Othman, F; Rofiee, MS; Vasudevan, M; Zakaria, ZA, 2012)
"The modulation of the cyclooxygenase-independent pathway by the green tea-derived polyphenol, epigallocatechin gallate (EGCG) during its healing action against indomethacin (IND)-induced stomach ulceration in mice was investigated."3.77Role of the COX-independent pathways in the ulcer-healing action of epigallocatechin gallate. ( Adhikary, B; Bandyopadhyay, SK; Chattopadhyay, S; Yadav, SK, 2011)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."3.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
"Septicemia occurred in a long-term hemodialysis patient on oral iron supplementation who had been treated for esophageal ulcer by omeprazole, an ulcer-healing drug."3.68Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation. ( Fakir, M; Hardin, JM; Matta, B; Saison, C; Wong, T, 1992)
"Omeprazole treatment increased R-R intervals (P = ."3.30Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses. ( Berryhill, EH; Finno, CJ; Knych, H; Louie, EW; Morgan, JM; Nieto, J; Wensley, F, 2023)
"omeprazole was shorter than that of 0."2.70Pharmacokinetics and pharmacodynamics of antiulcer agents in llama. ( Christensen, JM; Hollingshead, N; Huber, M; Limsakun, T; Smith, BB, 2001)
"Lansoprazole was superior to ranitidine in providing relief of upper abdominal burning and daytime heartburn (p < 0."2.68Lansoprazole heals erosive reflux esophagitis resistant to histamine H2-receptor antagonist therapy. ( Campbell, DR; Castell, D; Fleischmann, R; Kogut, DG; Lehman, GA; McFarland, M; Richter, J; Robinson, M; Sabesin, S; Sontag, SJ, 1997)
"The vast majority of patients with GERD have mild symptoms, no gross endoscopic evidence of esophagitis, and little risk of developing complications."2.39Influence of pathophysiology, severity, and cost on the medical management of gastroesophageal reflux disease. ( Reynolds, JC, 1996)
"Gastric ulcer is a chronic condition that occurs when the mucosa of the stomach is broken."1.91Gastro-Protective and Therapeutic Effect of Punica granatum against Stomach Ulcer Caused by Helicobacter Pylori. ( Alamri, ZZ; Faraj, RK; Hussein, MM; M Hussein, A; Mojarradgandoukmolla, S; Muhialdin, AJ; Taha, ZB, 2023)
"Drug-induced esophagitis is an uncommon diagnosis in the pediatric population."1.56L-arginine-induced esophagitis, report of six cases. ( Casaubón-Garcín, PR; Ferreiro-Marin, A; González-Cruz, MÁ; Parra, PR, 2020)
"Cytology from Barrett's esophagus can be misleading in the presence of severe inflammation."1.30Brush cytology in the diagnosis of neoplasia in Barrett's esophagus. ( Alderson, D; Hardwick, RH; Lott, M; Morgan, RJ; Warren, BF, 1997)
"Such chronic ulcers have been associated with pain, stricture formation, and recurrent hemorrhage."1.28Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy. ( Gimson, A; Polson, R; Westaby, D; Williams, R, 1990)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.13)18.7374
1990's20 (42.55)18.2507
2000's13 (27.66)29.6817
2010's5 (10.64)24.3611
2020's8 (17.02)2.80

Authors

AuthorsStudies
Abu El-Ella, SS1
El-Mekkawy, MS1
Mohamed Selim, A1
Zhang, J1
Yin, Y1
Xu, Q1
Che, X1
Yu, C1
Ren, Y1
Li, D1
Zhao, J1
Louie, EW2
Berryhill, EH2
Nieto, J2
Wensley, F2
Knych, H2
Finno, CJ2
Morgan, JM2
Gao, N2
Yan, S2
Chen, B2
Selim, HM1
Negm, WA1
Hawwal, MF1
Hussein, IA1
Elekhnawy, E1
Ulber, R1
Zayed, A1
Muhialdin, AJ1
Alamri, ZZ1
M Hussein, A1
Faraj, RK1
Taha, ZB1
Hussein, MM1
Mojarradgandoukmolla, S1
Abdel-Gawad, DRI1
Ibrahim, MA1
Moawad, UK1
Kamel, S1
El-Banna, HA1
El-Banna, AH1
Hassan, WH1
El-Ela, FIA1
Parra, PR1
González-Cruz, MÁ1
Ferreiro-Marin, A1
Casaubón-Garcín, PR1
Scarpignato, C1
Dolak, W1
Lanas, A1
Matzneller, P1
Renzulli, C1
Grimaldi, M1
Zeitlinger, M1
Bjarnason, I1
Fujimori, S1
Gudis, K1
Takahashi, Y1
Seo, T1
Yamada, Y1
Ehara, A1
Kobayashi, T1
Mitsui, K1
Yonezawa, M1
Tanaka, S1
Tatsuguchi, A1
Sakamoto, C1
Adhikary, B1
Yadav, SK1
Bandyopadhyay, SK1
Chattopadhyay, S1
Aleman, M1
Nieto, JE1
Higgins, JK1
Zakaria, ZA1
Abdul Hisam, EE1
Norhafizah, M1
Rofiee, MS1
Othman, F1
Hasiah, AH1
Vasudevan, M1
Guda, N1
Vakil, N1
Sawhney, MS1
Nelson, DB1
Curran, MP1
Wellington, K1
Akbulut, S1
Yavuz, B1
Köseoğlu, T1
Gököz, A1
Saritaş, U1
Shaheen, NJ1
Stuart, E1
Schmitz, SM1
Mitchell, KL1
Fried, MW1
Zacks, S1
Russo, MW1
Galanko, J1
Shrestha, R1
Hata, M1
Shiono, M1
Sekino, H1
Furukawa, H1
Sezai, A1
Iida, M1
Yoshitake, I1
Hattori, T1
Wakui, S1
Soeda, M1
Taoka, M1
Negishi, N1
Sezai, Y1
Alonso Fernández, M1
Dhippayom, T1
Walker, R1
Hawkey, CJ1
Ell, C1
Simon, B1
Albert, J1
Keuchel, M1
McAlindon, M1
Fortun, P1
Schumann, S1
Bolten, W1
Shonde, A1
Hugot, JL1
Yu, V1
Arulmani, U1
Krammer, G1
Rebuli, R1
Toth, E1
Konda, A1
Cappell, MS1
Dieterle, L1
Haines, DE1
Garg, PK1
Sidhu, SS1
Bhargava, DK1
Bataller, R1
Bordas, JM1
Ordi, J1
Llach, J1
Elizalde, JI1
Mondelo, F1
Jaspersen, D2
Körner, T2
Schorr, W2
Hammar, CH2
Yuki, H1
Kamato, T1
Nishida, A1
Ohta, M1
Shikama, H1
Yanagisawa, I1
Miyata, K1
Papich, MG1
Sarda, H1
Allisy, C1
Le Loc'h, H1
Benhamou, PH1
Vannerom, PY1
García Rodríguez, LA1
Mannino, S1
Wallander, MA1
Lindblom, B1
Reynolds, JC1
Sontag, SJ1
Kogut, DG1
Fleischmann, R1
Campbell, DR1
Richter, J1
Robinson, M1
McFarland, M1
Sabesin, S1
Lehman, GA1
Castell, D1
Hardwick, RH1
Morgan, RJ1
Warren, BF1
Lott, M1
Alderson, D1
Kyzer, S1
Gelber, E1
Rabinovich, Y1
Lurie, B1
Binder, Y1
Chaimoff, C1
Fendrick, AM1
Scheiman, JM1
Kobayashi, S1
Kawabe, N1
Miyata, F1
Ito, H1
Kazumiya, H1
Murase, K1
Kurokawa, S1
Fujishima, K1
Borum, ML1
Marks, ZH1
Emami, AJ1
Morrison, M1
Rammage, L1
Bosch, D1
Stolte, M1
Vieth, M1
Schmitz, JM1
Alexandridis, T1
Seifert, E1
Christensen, JM1
Limsakun, T1
Smith, BB1
Hollingshead, N1
Huber, M1
Byrne, M1
Sheehan, K1
Kay, E1
Patchett, S1
Johlin, FC1
Labrecque, DR1
Neil, GA1
Fakir, M1
Saison, C1
Wong, T1
Matta, B1
Hardin, JM1
Joly, P1
Chosidow, O1
Laurent-Poig, P1
Delchier, JC1
Roujeau, JC1
Revuz, J1
Gimson, A1
Polson, R1
Westaby, D1
Williams, R1
Jansen, JB1
Lamers, CB1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind, Placebo-controlled Study of the Safety and Efficacy of Eszopiclone in the Treatment of Insomnia in Patients With Chronic Low Back Pain[NCT00365976]Phase 458 participants (Actual)Interventional2006-08-31Completed
A Randomized Controlled Trial Comparing Proton Pump Inhibitor Therapy With and Without Interarytenoid Botulinum Toxin Injection for Vocal Fold Granuloma[NCT01678053]Phase 20 participants (Actual)Interventional2012-09-30Withdrawn (stopped due to Was not able to recruit patients for randomization.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hamilton Depression Rating Scale (HAM-D-24)

The Hamilton Depression Scale - 24 Items (HAM-D-24) measures depression severity. Items are rated on a scale from 0 (symptoms not present) to a maximum of 2 to 4 (symptom extremely severe) for a total score range of 0 to 76. The higher the score, the more severe. (NCT00365976)
Timeframe: prenaprosyn baseline, postnaprosyn Baseline, Week 1, Week 2, week 4

,
Interventionunits on a scale (Mean)
prenaprosyn Baselinepostnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone6.456.384.544.142.62
Placebo7.106.575.535.076.21

Insomnia Severity Index (ISI)

The ISI is a seven-item self-report questionnaire that provides a global measure of insomnia severity based on difficulty falling or staying asleep, satisfaction with sleep, or degree of impairment with daytime functioning. The total score ranges from 0-28: 0-7 (no clinical insomnia), 8-14 (subthreshold insomnia), 15-21 (insomnia of moderate severity), and 22-28 (severe insomnia). (NCT00365976)
Timeframe: Prenaprosyn Baseline, Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
Prenaprosyn BaselinePostnaprosyn baselineWeek 1Week 2Week 4
Eszopiclone18.8518.0011.2810.618.38
Placebo20.2616.7812.8512.7413.75

Mean Sleep Onset Latency (SOL)

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionminutes (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone38.2822.3617.5015.28
Placebo34.1127.0023.1019.91

Mean Subjective Sleep Diary Derived Total Sleep Time (TST)

Nightly total sleep time was averaged from diary entries. (NCT00365976)
Timeframe: Postnaprosyn baseline, Week 1, week 2, week 4

,
InterventionMinutes (Mean)
postnaprosyn baselineweek 1week 2Week 4
Eszopiclone316.96403.47421.97411.97
Placebo380.45375.56382.11388.96

Number of Awakenings

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionawakenings (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone2.291.311.351.33
Placebo2.081.982.132.34

Patient Global Impression of Pain Ratings

Pain ratings included a global impression of pain rating (PGI) (1-5 rating with 1 being little pain and 5 is worst pain) (NCT00365976)
Timeframe: postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone4.023.543.303.08
Placebo3.903.824.013.80

Roland Morris Low Back Pain Inventory (RMLBPI)

"The Roland-Morris Low Back Pain Disability Questionnaire (RMLBPDQ) is a 24-item instrument that assesses the extent to which activities of daily living are affected by LBP. It is composed of 24 yes-no items assessing potential disabilities.~Scores range from 0 (no disability) to 24 (severe disability)." (NCT00365976)
Timeframe: prenaprosyn baseline, postnaprosyn Baseline, Week 1, Week 2, week 4

,
Interventionunits on a scale (Mean)
prenaprosyn Baselinepostnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone12.279.979.107.636.59
Placebo11.3310.309.059.327.94

Sleep Quality Ratings

Sleep quality ratings are based on a 1-10 Likert scale. Low scores represent poorer sleep quality and higher scores represent better quality sleep (NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone4.525.996.186.38
Placebo4.444.905.335.29

Visual Analog Scale Pain Ratings (VAS)

Scores are measured on a 100 mm Visual Analog Scale (VAS). The VAS scale ranges from 0 to 100 mm with the lower score indicating less pain and the higher score indicating greater pain (NCT00365976)
Timeframe: Postnaprosyn baseline, Week 1, Week 2, Week 4

,
Interventionunits on a scale (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone48.5140.7234.7031.69
Placebo53.7951.9951.2551.60

Wake Time After Sleep Onset

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionminutes (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone91.5149.3437.0736.74
Placebo81.4376.7181.3276.18

Reviews

5 reviews available for omeprazole and Ulcer

ArticleYear
Delayed-release lansoprazole plus naproxen.
    Drugs, 2004, Volume: 64, Issue:17

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents;

2004
Antiulcer therapy.
    The Veterinary clinics of North America. Small animal practice, 1993, Volume: 23, Issue:3

    Topics: Animals; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cats; Cimetidine; Dog

1993
Influence of pathophysiology, severity, and cost on the medical management of gastroesophageal reflux disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Nov-15, Volume: 53, Issue:22 Suppl 3

    Topics: Aged; Anti-Ulcer Agents; Cisapride; Drug Interactions; Drug Therapy, Combination; Esophagitis, Pepti

1996
Esophageal stricture from idiopathic ulcers in an AIDS patient: a case report and review of the literature.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Ulcer Agents; Biopsy; Endoscopy, Digestive System; E

1999
Omeprazole in the short-term treatment of reflux oesophagitis.
    Digestion, 1989, Volume: 44 Suppl 1

    Topics: Drug Administration Schedule; Esophagitis, Peptic; Gastric Acid; Humans; Omeprazole; Ulcer

1989

Trials

11 trials available for omeprazole and Ulcer

ArticleYear
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Rifaximin Reduces the Number and Severity of Intestinal Lesions Associated With Use of Nonsteroidal Anti-Inflammatory Drugs in Humans.
    Gastroenterology, 2017, Volume: 152, Issue:5

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Delayed-Ac

2017
Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: a randomized, controlled trial.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Double-Blind Method; Esophageal and Gastric

2005
Prospective randomized trial for optimal prophylactic treatment of the upper gastrointestinal complications after open heart surgery.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Cardiac Surgical Procedu

2005
Less small-bowel injury with lumiracoxib compared with naproxen plus omeprazole.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:5

    Topics: Administration, Oral; Adult; Aged; Capsule Endoscopes; Cross-Over Studies; Cyclooxygenase Inhibitors

2008
Role of omeprazole in prevention and treatment of postendoscopic variceal sclerotherapy esophageal complications. Double-blind randomized study.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Esophageal and Gastric Varices; Eso

1995
Omeprazole in the management of sclerotherapy-induced esophageal ulcers resistant to H2 blocker treatment.
    Journal of gastroenterology, 1995, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Drug Resistance; Esophageal and Gastric Varices; Esophageal Diseases

1995
Lansoprazole heals erosive reflux esophagitis resistant to histamine H2-receptor antagonist therapy.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Antacids; Anti-Ulcer Agents; Double-Blind Meth

1997
Healing and prevention of NSAID-associated ulcer disease: is seeing believing?
    The American journal of gastroenterology, 1998, Volume: 93, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Double-Blind Method; Endoscopy; Humans;

1998
Effects of long-term treatment with proton pump inhibitors in gastro-oesophageal reflux disease on the histological findings in the lower oesophagus.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Barrett Esophagus; Double-Blind Method;

2000
Pharmacokinetics and pharmacodynamics of antiulcer agents in llama.
    Journal of veterinary pharmacology and therapeutics, 2001, Volume: 24, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Area Under Curve; Camelids, New World; Dose-Response Relationship, Drug;

2001

Other Studies

31 other studies available for omeprazole and Ulcer

ArticleYear
Stress ulcer prophylaxis for critically ill children: routine use needs to be re-examined.
    Anales de pediatria, 2022, Volume: 96, Issue:5

    Topics: Acute Disease; Child; Critical Illness; Gastrointestinal Hemorrhage; Humans; Omeprazole; Peptic Ulce

2022
Integrated serum pharmacochemistry and investigation of the anti-gastric ulcer effect of Zuojin pill in rats induced by ethanol.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Drugs, Chinese Herbal; Ethanol; Gastric Mucosa; Male; Omep

2022
Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Ga

2023
Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Ga

2023
Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Ga

2023
Effects of lansoprazole and omeprazole Combined With Antimicrobial Agents on Gastric Juice pH and Inflammatory Factors in Elderly Patients With Hp Positive Gastric Ulcer.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Ga

2023
Fucoidan mitigates gastric ulcer injury through managing inflammation, oxidative stress, and NLRP3-mediated pyroptosis.
    International immunopharmacology, 2023, Volume: 120

    Topics: Animals; Ethanol; Gastric Mucosa; Glutathione; Inflammation; Male; Mice; NF-kappa B; NLR Family, Pyr

2023
Gastro-Protective and Therapeutic Effect of Punica granatum against Stomach Ulcer Caused by Helicobacter Pylori.
    Cellular and molecular biology (Noisy-le-Grand, France), 2023, Jan-31, Volume: 69, Issue:1

    Topics: Amoxicillin; Animals; Helicobacter Infections; Helicobacter pylori; Omeprazole; Pomegranate; Rats; S

2023
Effectiveness of natural biomaterials in the protection and healing of experimentally induced gastric mucosa Ulcer in rats.
    Molecular biology reports, 2023, Volume: 50, Issue:11

    Topics: Amygdalin; Animals; Anti-Ulcer Agents; Ethanol; Gastric Mucosa; Histamine; Omeprazole; Plant Extract

2023
L-arginine-induced esophagitis, report of six cases.
    Boletin medico del Hospital Infantil de Mexico, 2020, Volume: 77, Issue:1

    Topics: Adolescent; Arginine; Chest Pain; Child; Deglutition Disorders; Esophageal Mucosa; Esophagitis; Fema

2020
Distribution of small intestinal mucosal injuries as a result of NSAID administration.
    European journal of clinical investigation, 2010, Volume: 40, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Diclofenac; Humans; Intestinal Di

2010
Role of the COX-independent pathways in the ulcer-healing action of epigallocatechin gallate.
    Food & function, 2011, Volume: 2, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Catechin; Gene Expression Regulation; Intercellular Adhesion Molecule-1;

2011
Ulcerative cystitis associated with phenylbutazone administration in two horses.
    Journal of the American Veterinary Medical Association, 2011, Aug-15, Volume: 239, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cystitis; Hematuria; Horse Dise

2011
Methanol extract of Bauhinia purpurea leaf possesses anti-ulcer activity.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2012, Volume: 21, Issue:5

    Topics: Animals; Bauhinia; Dose-Response Relationship, Drug; Gastrointestinal Agents; Indomethacin; Male; Me

2012
Low-dose aspirin: protection from the panacea.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents;

2002
An aspirin a day keeps the cardiologist away (but what about the gastroenterologist?).
    Gastroenterology, 2003, Volume: 124, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Dru

2003
Crohn's disease with isolated esophagus and gastric involvement.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2004, Volume: 15, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Azathioprine; Biopsy; Crohn Disease; Endoscopy, Gastrointestinal; Esophage

2004
[Oesophageal ulcer and doxycycline].
    Atencion primaria, 2005, Sep-15, Volume: 36, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Doxycycline; Drug Therapy, Combination; Esophageal Disease

2005
Impact of the reclassification of omeprazole on the prescribing and sales of ulcer healing drugs.
    Pharmacy world & science : PWS, 2006, Volume: 28, Issue:4

    Topics: Anti-Ulcer Agents; Drug Industry; Drug Prescriptions; Drug Utilization Review; Health Services Needs

2006
Esophageal ulceration from high-intensity focused US catheter ablation for pulmonary vein isolation: a novel complication in the treatment of symptomatic refractory atrial fibrillation.
    Gastrointestinal endoscopy, 2008, Volume: 68, Issue:3

    Topics: Atrial Fibrillation; Catheter Ablation; Drug Therapy, Combination; Esophageal Diseases; Esophagoscop

2008
Upper gastrointestinal bleeding: a complication of "inlet patch mucosa" in the upper esophagus.
    Endoscopy, 1995, Volume: 27, Issue:3

    Topics: Adult; Biopsy, Needle; Endoscopy, Digestive System; Esophageal Diseases; Gastric Mucosa; Gastrointes

1995
Antisecretory and antiulcer effects of YM020, a new H+,K(+)-ATPase inhibitor, in rats and dogs.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:1

    Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Gastric Acid; His

1995
[Omeprazole in H2-receptor blockader-refractory sclerosing ulcers of the esophagus].
    Deutsche medizinische Wochenschrift (1946), 1993, May-07, Volume: 118, Issue:18

    Topics: Esophageal and Gastric Varices; Esophageal Stenosis; Humans; Omeprazole; Polidocanol; Polyethylene G

1993
[Efficacy and good tolerance of omeprazole in a case of refractory ulcerative esophagitis in the child].
    Archives francaises de pediatrie, 1993, Volume: 50, Issue:1

    Topics: Child, Preschool; Drug Tolerance; Esophagitis; Humans; Male; Omeprazole; Ulcer

1993
A cohort study of the ocular safety of anti-ulcer drugs.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Cohort Studies; Eye Diseases; Female; Humans; Male; Middle Aged; Ome

1996
Brush cytology in the diagnosis of neoplasia in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1997, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cell Count; Cell Nucleus; Chromatin; C

1997
Massively bleeding gastric pouch ulcer after silastic ring vertical gastroplasty successfully treated endoscopically: a report of two cases.
    Obesity surgery, 1997, Volume: 7, Issue:2

    Topics: Anti-Ulcer Agents; Epinephrine; Ethanol; Female; Gastrointestinal Hemorrhage; Gastroplasty; Hemostas

1997
[A case of Behcet's syndrome associated with esophageal ulcer].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, Dec-10, Volume: 87, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents; Anti-Ulcer Agents; Behcet

1998
Treatment of laryngeal contact ulcers and granulomas: a 12-year retrospective analysis.
    Journal of voice : official journal of the Voice Foundation, 1999, Volume: 13, Issue:4

    Topics: Adult; Aged; Anti-Ulcer Agents; Botulinum Toxins, Type A; Female; Granuloma; Humans; Laryngeal Disea

1999
Symptomatic ulceration of an acid-producing oesophageal inlet patch colonized by helicobacter pylori.
    Endoscopy, 2002, Volume: 34, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Endoscopes; Esophagus; Helicobact

2002
Omeprazole heals mucosal ulcers associated with endoscopic injection sclerotherapy.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:9

    Topics: Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Esophageal Diseases; Female; Humans; Male; M

1992
Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 19, Issue:3

    Topics: Aged; Anemia, Hypochromic; Bacteremia; Esophageal Diseases; Female; Ferrous Compounds; Humans; Omepr

1992
[Possibility of prednisone-omeprazole interference in bullous pemphigoid].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:8-9

    Topics: Adult; Drug Interactions; Female; Humans; Omeprazole; Pemphigoid, Bullous; Prednisone; Recurrence; U

1990
Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy.
    Gastroenterology, 1990, Volume: 99, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Esophageal Diseases; Follow-Up Studies; Humans; Injections; Middle A

1990