omeprazole has been researched along with Stevens-Johnson Syndrome in 11 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After 2 months of treatment with imatinib 400 mg/day, a 60-year-old white female affected by GIST developed bilateral palpebral edema with hyperemic conjunctivae and labial edema when lansoprazole 15 mg/day was introduced to treat dyspeptic symptomatology." | 7.73 | Adverse reactions during imatinib and lansoprazole treatment in gastrointestinal stromal tumors. ( Ardau, R; Chillotti, C; De Lisa, R; Del Zompo, M; Severino, G, 2005) |
| "Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) have been associated with some drugs, particularly anticonvulsants such as phenytoin." | 3.74 | [Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy]. ( Fernández, FA; Garcés, FJ; Pintor, E; Quesada, R, 2007) |
| "After 2 months of treatment with imatinib 400 mg/day, a 60-year-old white female affected by GIST developed bilateral palpebral edema with hyperemic conjunctivae and labial edema when lansoprazole 15 mg/day was introduced to treat dyspeptic symptomatology." | 3.73 | Adverse reactions during imatinib and lansoprazole treatment in gastrointestinal stromal tumors. ( Ardau, R; Chillotti, C; De Lisa, R; Del Zompo, M; Severino, G, 2005) |
| "A diagnosis of toxic epidermal necrolysis (TEN) was made." | 2.45 | Toxic epidermal necrolysis and neutropaenia: complications of omeprazole. ( Burke, A; Burns, A; Handfield-Jones, S; Palmer, M; Sinha, A; Thakor, AS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Van Tendeloo, E | 1 |
| Gutermuth, J | 1 |
| Grosber, M | 1 |
| Ladizinski, B | 1 |
| Sankey, C | 1 |
| Roman, J | 1 |
| Nguyen, KD | 1 |
| Dominguez, AR | 1 |
| Thakor, AS | 1 |
| Burke, A | 1 |
| Handfield-Jones, S | 1 |
| Sinha, A | 1 |
| Palmer, M | 1 |
| Burns, A | 1 |
| Chularojanamontri, L | 1 |
| Jiamton, S | 1 |
| Manapajon, A | 1 |
| Suvanasuthi, S | 1 |
| Kulthanan, K | 1 |
| Dhana, N | 1 |
| Jongjarearnprasert, K | 1 |
| Severino, G | 1 |
| Chillotti, C | 1 |
| De Lisa, R | 1 |
| Del Zompo, M | 1 |
| Ardau, R | 1 |
| Heaton, NR | 1 |
| Edmonds, EV | 1 |
| Francis, ND | 1 |
| Bunker, CB | 1 |
| Bowling, JC | 1 |
| Morar, N | 1 |
| Revuz, J | 1 |
| Fernández, FA | 1 |
| Pintor, E | 1 |
| Quesada, R | 1 |
| Garcés, FJ | 1 |
| Cox, NH | 1 |
1 review available for omeprazole and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Toxic epidermal necrolysis and neutropaenia: complications of omeprazole.
Topics: Acute Kidney Injury; Adult; Biopsy, Needle; Combined Modality Therapy; Diabetes Mellitus, Type 1; Di | 2009 |
10 other studies available for omeprazole and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Positive patch testing with omeprazole in Stevens-Johnson syndrome: a case report.
Topics: Humans; Omeprazole; Patch Tests; Stevens-Johnson Syndrome | 2021 |
A topical matter: toxic epidermal necrolysis.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antiemetics; Antineopl | 2014 |
A diffuse desquamative rash in an elderly male.
Topics: Aged; Calcium Channel Blockers; Diagnosis, Differential; Diltiazem; Humans; Lupus Erythematosus, Cut | 2017 |
Cutaneous reactions to proton pump inhibitors: a case-control study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Angioedema; Cas | 2012 |
Adverse reactions during imatinib and lansoprazole treatment in gastrointestinal stromal tumors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antineoplastic Agents; Benzamides; Drug Eruptions; Edema; F | 2005 |
Fatal toxic epidermal necrolysis due to lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Drug Eruptions; Erythema Multiform | 2004 |
Fatal toxic epidermal necrolysis due to lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Diagnosis, Differential; Drug Eruptions; | 2006 |
[Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy].
Topics: Adenocarcinoma; Aged; Anticonvulsants; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; | 2007 |
Pantoprazole (Protonix).
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Clinical Trials as Topic; Dose-Response Rel | 2000 |
Acute disseminated epidermal necrosis due to omeprazole.
Topics: Acute Disease; Aged; Diagnosis, Differential; Erythema Multiforme; Female; Humans; Omeprazole; Pemph | 1992 |