omeprazole and Sleep Wake Disorders
omeprazole has been researched along with Sleep Wake Disorders in 5 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"The effect of gastro-oesophageal reflux on sleep and sleep quality is highly controversial." | 5.33 | The effect of gastro-oesophageal reflux and omeprazole on key sleep parameters. ( Banwait, KS; Cohen, S; Dimarino, AJ; Dimarino, M; Doghramji, K; Eschinger, E; Greenberg, A, 2005) |
"Rabeprazole treatment significantly improved subjective indices of sleep quality." | 2.71 | The effect of acid suppression on sleep patterns and sleep-related gastro-oesophageal reflux. ( Goodrich, S; Orr, WC; Robert, J, 2005) |
"The consequences of nocturnal gastroesophageal reflux disease (GERD) may be greater than daytime GERD in terms of clinical complications such as increased risk of esophageal lesions and respiratory conditions, as well as issues of health-related quality of life, sleep, work productivity, and economics." | 2.44 | Nocturnal gastroesophageal reflux disease: issues, implications, and management strategies. ( Johnson, DA; Katz, PO, 2008) |
"Acid reflux esophagitis was induced by ligating the transitional region between the forestomach and the glandular portion and then wrapping the duodenum near the pylorus." | 1.40 | Acid reflux directly causes sleep disturbances in rat with chronic esophagitis. ( Arakawa, T; Fujiwara, Y; Nakahara, K; Shiba, M; Tanigawa, T; Tominaga, K; Tsukahara, T; Urade, Y; Watanabe, T; Yamagami, H, 2014) |
"The effect of gastro-oesophageal reflux on sleep and sleep quality is highly controversial." | 1.33 | The effect of gastro-oesophageal reflux and omeprazole on key sleep parameters. ( Banwait, KS; Cohen, S; Dimarino, AJ; Dimarino, M; Doghramji, K; Eschinger, E; Greenberg, A, 2005) |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (80.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Nakahara, K | 1 |
Fujiwara, Y | 1 |
Tsukahara, T | 1 |
Yamagami, H | 1 |
Tanigawa, T | 1 |
Shiba, M | 1 |
Tominaga, K | 1 |
Watanabe, T | 1 |
Urade, Y | 1 |
Arakawa, T | 1 |
Johnson, DA | 1 |
Katz, PO | 1 |
Orr, WC | 1 |
Goodrich, S | 1 |
Robert, J | 1 |
Dimarino, AJ | 1 |
Banwait, KS | 1 |
Eschinger, E | 1 |
Greenberg, A | 1 |
Dimarino, M | 1 |
Doghramji, K | 1 |
Cohen, S | 1 |
Huuhka, K | 1 |
Riutta, A | 1 |
Haataja, R | 1 |
Ylitalo, P | 1 |
Leinonen, E | 1 |
Clinical Trials (2)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features in a Primary Care Setting: A Pragmatic, Randomized, Single Blind Study[NCT04028466] | Phase 4 | 82 participants (Actual) | Interventional | 2019-05-26 | Terminated (stopped due to Budget for the study was withdrawn and discontinued) | ||
The Effect Of Pantoprazole 40 mg Once Daily Versus Placebo On The Power Spectral Analysis Of The Sleep Electroencephalogram (EEG) Of Patients With Gastroesophageal Reflux Disease (GERD)[NCT00674245] | Phase 2/Phase 3 | 40 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
1 review available for omeprazole and Sleep Wake Disorders
Article | Year |
---|---|
Nocturnal gastroesophageal reflux disease: issues, implications, and management strategies.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Gastroesophageal Reflux; Heartburn; Humans; Lansoprazole; O | 2008 |
Trials
2 trials available for omeprazole and Sleep Wake Disorders
Article | Year |
---|---|
The effect of acid suppression on sleep patterns and sleep-related gastro-oesophageal reflux.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antacids; Anti-Ulcer Agents; Benzimidazoles; Female; | 2005 |
The effect of CYP2C19 substrate on the metabolism of melatonin in the elderly: A randomized, double-blind, placebo-controlled study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anticonvulsants; Antidepressive Ag | 2006 |
Other Studies
2 other studies available for omeprazole and Sleep Wake Disorders
Article | Year |
---|---|
Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.
Topics: Animals; Chronic Disease; Esophagitis, Peptic; Esophagus; Gastric Acid; Gastric Juice; Gastroesophag | 2014 |
The effect of gastro-oesophageal reflux and omeprazole on key sleep parameters.
Topics: Adolescent; Adult; Anti-Ulcer Agents; Case-Control Studies; Female; Gastroesophageal Reflux; Humans; | 2005 |