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omeprazole and Sleep Apnea, Obstructive

omeprazole has been researched along with Sleep Apnea, Obstructive in 8 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

ExcerptRelevanceReference
"We investigated whether the treatment of gastrooesophageal reflux with omeprazole is able to decrease apnoea attacks."9.12Obstructive sleep apnoea is improved by a prolonged treatment of gastrooesophageal reflux with omeprazole. ( Bortolotti, M; Gentilini, L; Giovannini, M; Morselli, C, 2006)
"We investigated whether the treatment of gastrooesophageal reflux with omeprazole is able to decrease apnoea attacks."5.12Obstructive sleep apnoea is improved by a prolonged treatment of gastrooesophageal reflux with omeprazole. ( Bortolotti, M; Gentilini, L; Giovannini, M; Morselli, C, 2006)
" After 3-month treatment with Pantoprazole, a statistically significant improvement was noted for daytime sleepiness (P = ."3.72Pantoprazole for sleepiness associated with acid reflux and obstructive sleep disordered breathing. ( Steward, DL, 2004)
"To evaluate the relationship between gastroesophageal reflux (GER) and obstructive sleep apnea (OSA) and the effect of combined therapy with cisapride and omeprazole."3.70[The relationship between obstructive sleep apnea and gastroesophageal reflux and the effect of antireflux therapy]. ( Huang, X; Ke, M; Wang, Z; Xiao, G, 1999)
"Questionnaire screening for GERD in children with OSAS may be of benefit."2.77Respiratory response to proton pump inhibitor treatment in children with obstructive sleep apnea syndrome and gastroesophageal reflux disease. ( Cudowska, B; Dębkowska, K; Kaczmarski, M; Klukowski, M; Semeniuk, J; Wasilewska, J, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nannapaneni, S1
Olson, E1
Ramar, K1
Wasilewska, J1
Semeniuk, J1
Cudowska, B1
Klukowski, M1
Dębkowska, K1
Kaczmarski, M1
Steward, DL1
Bortolotti, M1
Gentilini, L1
Morselli, C1
Giovannini, M1
Esteller, E1
Modolell, I1
Segarra, F1
Matiño, E1
Enrique, A1
Ademà, JM1
Estivill, E1
Talwar, V1
de Caestecker, JS1
Nasr, VG1
Bitar, MA1
Chehade, JM1
Dagher, WI1
Baraka, AS1
Xiao, G1
Wang, Z1
Ke, M1
Huang, X1

Trials

2 trials available for omeprazole and Sleep Apnea, Obstructive

ArticleYear
Respiratory response to proton pump inhibitor treatment in children with obstructive sleep apnea syndrome and gastroesophageal reflux disease.
    Sleep medicine, 2012, Volume: 13, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentra

2012
Obstructive sleep apnoea is improved by a prolonged treatment of gastrooesophageal reflux with omeprazole.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2006, Volume: 38, Issue:2

    Topics: Aged; Anti-Ulcer Agents; Comorbidity; Double-Blind Method; Female; Gastroesophageal Reflux; Humans;

2006

Other Studies

6 other studies available for omeprazole and Sleep Apnea, Obstructive

ArticleYear
Nocturnal vocalization.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2014, Feb-15, Volume: 10, Issue:2

    Topics: Adult; Continuous Positive Airway Pressure; Female; Gastroesophageal Reflux; Hiccup; Humans; Omepraz

2014
Pantoprazole for sleepiness associated with acid reflux and obstructive sleep disordered breathing.
    The Laryngoscope, 2004, Volume: 114, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Arousal; Benzimidazoles; Circadia

2004
[Gastroesophageal reflux and obstructive sleep apnea syndrome].
    Acta otorrinolaringologica espanola, 2005, Volume: 56, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Female; Gastroesophageal Reflux; Hum

2005
What is the relationship between gastro-oesophageal reflux and obstructive sleep apnoea?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2006, Volume: 38, Issue:2

    Topics: Anti-Ulcer Agents; Causality; Comorbidity; Gastroesophageal Reflux; Humans; Omeprazole; Proton Pump

2006
Postoperative severe uvular edema following tonsillectomy in a child with a history of obstructive sleep apnea.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Adenoids; Antiemetics; Catheter Ablation; Domperidone; Edema; Enzyme Inhibitors; Humans; Infant; Mal

2008
[The relationship between obstructive sleep apnea and gastroesophageal reflux and the effect of antireflux therapy].
    Zhonghua nei ke za zhi, 1999, Volume: 38, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Drug Therapy, Combination; Female; Gastroesophageal Reflux; Hum

1999