Page last updated: 2024-11-01

omeprazole and Rhabdomyolysis

omeprazole has been researched along with Rhabdomyolysis in 6 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"Polymyositis occurring in patients treated with omeprazole has been signalled as a possible adverse drug reaction (ADR) by the New Zealand Intensive Medicines Monitoring Programme (IMMP) and the WHO Collaborating Centre for International Drug Monitoring: the Uppsala Monitoring Centre (UMC)."4.83Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors? ( Clark, DW; Strandell, J, 2006)
" We report on the case of an emergency department patient with omeprazole-induced hyponatremic delirium and rhabdomyolysis."3.74Proton pump inhibitor-induced rhabdomyolysis and hyponatremic delirium. ( Bebarta, VS; King, JA; McDonough, M, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tanaka, K1
Nakada, TA1
Abe, R1
Itoga, S1
Nomura, F1
Oda, S1
Nozaki, M1
Suzuki, T1
Hirano, M1
Clark, DW1
Strandell, J1
Bebarta, VS1
King, JA1
McDonough, M1
Yusoff, IF1
Nairn, P1
Morgan, CA1
Dehesa, C1
Kassel, G1

Reviews

1 review available for omeprazole and Rhabdomyolysis

ArticleYear
Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors?
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adverse Drug Reaction Reporting Systems; Enzyme Inhibitors;

2006

Other Studies

5 other studies available for omeprazole and Rhabdomyolysis

ArticleYear
Omeprazole-associated rhabdomyolysis.
    Critical care (London, England), 2014, Jul-24, Volume: 18, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Duodenal Ulcer; Humans; Male; Omeprazole; Proton Pump Inhibitors; Rhabdomy

2014
Rhabdomyolysis associated with omeprazole.
    Journal of gastroenterology, 2004, Volume: 39, Issue:1

    Topics: Anti-Ulcer Agents; Humans; Male; Middle Aged; Omeprazole; Rhabdomyolysis

2004
Proton pump inhibitor-induced rhabdomyolysis and hyponatremic delirium.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:4

    Topics: Delirium; Humans; Hyponatremia; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Rhabdomyolysi

2008
Multiple organ failure related to pantoprazole.
    Australian and New Zealand journal of medicine, 1999, Volume: 29, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acidosis, Lactic; Acute Kidney Injury; Aged; Anti-Ulcer Age

1999
Multiple organ failure and pantoprazole.
    Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Humans; Multiple Organ F

2000