omeprazole has been researched along with Polyps in 38 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Polyps: Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple gastric polyps have been reported to occur in adults receiving omeprazole therapy." | 7.71 | Gastric polyps and nodules in children receiving long-term omeprazole therapy. ( Israel, DM; Pashankar, DS, 2002) |
| "In patients undergoing long-term treatment with omeprazole, tiny gastric polyps, described histologically as glandular cysts, have occasionally been reported." | 7.69 | Observation of gastric glandular cysts in the corpus mucosa of the stomach under omeprazole treatment. ( Armbrecht, U; Bethke, B; Goldbrunner, P; Lütke, A; Rabast, U; Seifert, E; Stolte, M, 1995) |
| "Three women and three men developed fundic gland polyps after 1-5 yr of omeprazole therapy, 20 mg/day." | 7.69 | Fundic gland polyps developing during omeprazole therapy. ( el-Zimaity, HM; Graham, DY; Jackson, FW, 1997) |
| " Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts." | 5.35 | [Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole]. ( Chae, HS; Cho, YS; Choi, KY; Han, SW; Kim, HK; Kim, JS; Park, YW; Son, HS, 2008) |
| "Forty-eight patients with hyperplastic gastric polyps (3-10 mm in diameter) infected with H pylori were randomly assigned to a treatment group (n = 24) which received proton-pump inhibitor (omeprazole or lansoprazole), clarithromycin, bismuth citrate and tinidazole, and a control group (n = 24) which received protective agent of gastric mucosa (tepretone)." | 5.12 | Effect of drug treatment on hyperplastic gastric polyps infected with Helicobacter pylori: a randomized, controlled trial. ( Chen, JY; Ji, F; Li, YM; Ning, JW; Wang, QY; Wang, ZW, 2006) |
| "Multiple gastric polyps have been reported to occur in adults receiving omeprazole therapy." | 3.71 | Gastric polyps and nodules in children receiving long-term omeprazole therapy. ( Israel, DM; Pashankar, DS, 2002) |
| "In patients undergoing long-term treatment with omeprazole, tiny gastric polyps, described histologically as glandular cysts, have occasionally been reported." | 3.69 | Observation of gastric glandular cysts in the corpus mucosa of the stomach under omeprazole treatment. ( Armbrecht, U; Bethke, B; Goldbrunner, P; Lütke, A; Rabast, U; Seifert, E; Stolte, M, 1995) |
| "Three women and three men developed fundic gland polyps after 1-5 yr of omeprazole therapy, 20 mg/day." | 3.69 | Fundic gland polyps developing during omeprazole therapy. ( el-Zimaity, HM; Graham, DY; Jackson, FW, 1997) |
| " Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts." | 1.35 | [Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole]. ( Chae, HS; Cho, YS; Choi, KY; Han, SW; Kim, HK; Kim, JS; Park, YW; Son, HS, 2008) |
| "Gastroesophageal reflux (GER) can cause serious voice problems and laryngopharyngeal disorders influencing the patient's quality of life." | 1.33 | Voice disorders and gastroesophageal reflux. ( Hocevar-Boltezar, I; Jansa, R; Sereg-Bahar, M, 2005) |
| "Fundic gland polyps have been described either in association with genetic polyposis syndromes of the colon, or in a sporadic form." | 1.33 | Sporadic fundic gland polyps: clinico-pathologic features and associated diseases. ( Bellone, S; Caruso, S; Declich, P; Ferrara, A; Tavani, E, 2005) |
| " Long-term use of proton pump inhibitors may be associated with the presence of small gastric fundic gland polyps and hyperplastic polyps." | 1.30 | Proton pump inhibitor-associated gastric polyps: a retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics. ( Boyce, HW; Choudhry, U; Coppola, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (44.74) | 18.2507 |
| 2000's | 19 (50.00) | 29.6817 |
| 2010's | 2 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okazaki, Y | 1 |
| Kotani, K | 1 |
| Higashi, Y | 1 |
| Kim, JS | 1 |
| Chae, HS | 1 |
| Kim, HK | 1 |
| Cho, YS | 1 |
| Park, YW | 1 |
| Son, HS | 1 |
| Han, SW | 1 |
| Choi, KY | 1 |
| Alqutub, AN | 1 |
| Masoodi, I | 1 |
| Pashankar, DS | 1 |
| Israel, DM | 1 |
| Asaka, M | 1 |
| Yamamoto, T | 1 |
| Matsumoto, J | 1 |
| Kosaihira, T | 1 |
| Nomoto, M | 1 |
| Kitajima, S | 1 |
| Arima, T | 1 |
| Tanabe, H | 1 |
| Hara, H | 1 |
| Ohtubo, C | 1 |
| Miyokawa, N | 1 |
| Sano, H | 1 |
| Raghunath, AS | 1 |
| O'Morain, C | 1 |
| McLoughlin, RC | 1 |
| Sereg-Bahar, M | 1 |
| Jansa, R | 1 |
| Hocevar-Boltezar, I | 1 |
| Declich, P | 9 |
| Tavani, E | 7 |
| Ferrara, A | 3 |
| Caruso, S | 3 |
| Bellone, S | 7 |
| Kim, MS | 1 |
| Jung, HK | 1 |
| Jung, HS | 1 |
| Choi, JY | 1 |
| Na, YJ | 1 |
| Pyun, GW | 1 |
| Ryu, JH | 1 |
| Moon, IH | 1 |
| Jo, MS | 1 |
| Ji, F | 1 |
| Wang, ZW | 1 |
| Ning, JW | 1 |
| Wang, QY | 1 |
| Chen, JY | 1 |
| Li, YM | 1 |
| Omazzi, B | 1 |
| Gozzini, C | 5 |
| Bortoli, A | 5 |
| Prada, A | 5 |
| Stolte, M | 3 |
| Bethke, B | 1 |
| Seifert, E | 1 |
| Armbrecht, U | 1 |
| Lütke, A | 1 |
| Goldbrunner, P | 1 |
| Rabast, U | 1 |
| Handa, Y | 1 |
| Ietomi, K | 1 |
| Sakimura, K | 1 |
| Miyoshi, K | 1 |
| Tanaka, J | 1 |
| Fujimoto, K | 1 |
| Iwakiri, R | 1 |
| Koyama, T | 1 |
| Sakata, H | 1 |
| Ohyama, T | 1 |
| Mizuguchi, M | 1 |
| Tokunaga, O | 1 |
| Muller, AF | 1 |
| Pinder, S | 1 |
| Toghill, PJ | 1 |
| Reddrop, CJ | 1 |
| Graham, JR | 3 |
| el-Zimaity, HM | 1 |
| Jackson, FW | 1 |
| Graham, DY | 1 |
| Sironi, M | 1 |
| Naegels, S | 1 |
| Urbain, D | 1 |
| Galati, F | 1 |
| Baldacci, MP | 1 |
| Ambrosiani, L | 3 |
| Choudhry, U | 1 |
| Boyce, HW | 1 |
| Coppola, D | 1 |
| Ohkusa, T | 1 |
| Takashimizu, I | 1 |
| Fujiki, K | 1 |
| Suzuki, S | 1 |
| Shimoi, K | 1 |
| Horiuchi, T | 1 |
| Sakurazawa, T | 1 |
| Ariake, K | 1 |
| Ishii, K | 1 |
| Kumagai, J | 1 |
| Tanizawa, T | 1 |
| Nakajima, A | 1 |
| Matsuhashi, N | 1 |
| Yazaki, Y | 1 |
| Oka, T | 1 |
| Sugano, K | 1 |
| Grassini, R | 2 |
| Porcellati, M | 3 |
| Kume, K | 1 |
| Hirakoba, M | 1 |
| Murata, I | 1 |
| Yoshikawa, I | 1 |
| Otsuki, M | 1 |
| Vieth, M | 1 |
| Kazantsev, GB | 1 |
| Schwesinger, WH | 1 |
| Heim-Hall, J | 1 |
| Dent, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial[NCT01269788] | Phase 2/Phase 3 | 144 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for omeprazole and Polyps
| Article | Year |
|---|---|
[Guidelines in the management of Helicobacter pylori infection in Japan].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Clarithromycin; Drug Therapy, Combination; Gas | 2003 |
[A case of gastric fundic polyps during long-term treatment of reflux esophagitis with omeprazole].
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Esophagitis, Peptic; Female; Gastric Fundus; Humans; Ome | 2003 |
Review article: the long-term use of proton-pump inhibitors.
Topics: Age Factors; Enzyme Inhibitors; Gastritis, Atrophic; Gastroesophageal Reflux; Helicobacter Infection | 2005 |
Fundic gland polyps: a still elusive entity on the eve of the year 2000.
Topics: Adenomatous Polyposis Coli; Anti-Ulcer Agents; Female; Gardner Syndrome; Gastric Fundus; Gastric Muc | 2000 |
2 trials available for omeprazole and Polyps
| Article | Year |
|---|---|
Effect of drug treatment on hyperplastic gastric polyps infected with Helicobacter pylori: a randomized, controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar | 2006 |
Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; | 1998 |
32 other studies available for omeprazole and Polyps
| Article | Year |
|---|---|
Vanishing gastric hyperplastic polyps.
Topics: Aged; Anti-Ulcer Agents; Drug Substitution; Gastroesophageal Reflux; Humans; Male; Omeprazole; Polyp | 2019 |
[Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole].
Topics: Aged; Anti-Ulcer Agents; Gastric Fundus; Humans; Male; Omeprazole; Polyps; Stomach Neoplasms | 2008 |
A case of gastric polyposis in antral area of stomach following prolonged proton-pump therapy.
Topics: Adult; Anti-Ulcer Agents; Dyspepsia; Humans; Male; Omeprazole; Polyps; Proton Pump Inhibitors; Stoma | 2010 |
Gastric polyps and nodules in children receiving long-term omeprazole therapy.
Topics: Adolescent; Anti-Ulcer Agents; Child; Child, Preschool; Enzyme Inhibitors; Esophagitis, Peptic; Fema | 2002 |
[Disappearance of gastric adenocarcinoma in hyperplastic polyp after eradication of Heliobacter pylori. Report of a case].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combin | 2005 |
Voice disorders and gastroesophageal reflux.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Enzyme Inhibitors; Esophagoscopy; Female; Gastroesoph | 2005 |
Sporadic fundic gland polyps: clinico-pathologic features and associated diseases.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Esophagitis, Peptic; Female; Gastric Fundus; Gast | 2005 |
[A Case of Cronkhite-Canada syndrome showing resolution with Helicobacter pylori eradication and omeprazole].
Topics: Anti-Ulcer Agents; Colonic Polyps; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hyp | 2006 |
Fundic gland polyps and PPI: the Mozart effect of gastrointestinal pathology?
Topics: Enzyme Inhibitors; Gastric Fundus; Helicobacter Infections; Helicobacter pylori; Humans; Hyperplasia | 2006 |
Observation of gastric glandular cysts in the corpus mucosa of the stomach under omeprazole treatment.
Topics: Adult; Aged; Cysts; Diagnosis, Differential; Female; Gastric Mucosa; Gastroesophageal Reflux; Humans | 1995 |
[A case of multiple gastric hyperplastic polyps: onset during omeprazole therapy in scleroderma patient].
Topics: Aged; Esophagitis, Peptic; Female; Humans; Hyperplasia; Omeprazole; Polyps; Scleroderma, Systemic; S | 1994 |
Hyperplastic polyps following treatment of acute gastric ulcers.
Topics: Esophageal and Gastric Varices; Famotidine; Female; Humans; Hyperplasia; Middle Aged; Omeprazole; Po | 1994 |
Juvenile gastric polyposis: reduction in blood- and protein-losing gastropathy with omeprazole.
Topics: Adult; Anemia, Hypochromic; Diagnosis, Differential; Female; Gastritis, Hypertrophic; Humans; Omepra | 1994 |
Fundic gland polyps: a rare, innocuous, and reversible disturbance.
Topics: Female; Humans; Omeprazole; Polyps; Stomach Neoplasms | 1993 |
Gastric polyposis: onset during long-term therapy with omeprazole.
Topics: Humans; Omeprazole; Polyps; Stomach Neoplasms | 1993 |
Omeprazole and gastric polyposis in humans.
Topics: Humans; Omeprazole; Polyps; Stomach Diseases | 1993 |
Fundic gland polyps developing during omeprazole therapy.
Topics: Adult; Anti-Ulcer Agents; Barrett Esophagus; Female; Gastric Fundus; Humans; Male; Middle Aged; Omep | 1997 |
Fundic gland polyps: an innocuous curiosity possibly with important pathological associations.
Topics: Antigens, Nuclear; Biomarkers; Humans; Immunohistochemistry; Nuclear Proteins; Omeprazole; Polyps; P | 1997 |
Gastric acne: omeprazole-induced fundic gland polyposis.
Topics: Gastric Fundus; Gastroscopy; Humans; Omeprazole; Polyps; Stomach Neoplasms | 1998 |
Omeprazole and fundic gland polyps.
Topics: Aged; Anti-Ulcer Agents; Female; Gastric Fundus; Humans; Male; Middle Aged; Omeprazole; Polyps; Stom | 1998 |
Do fundic gland polyps develop under long-term omeprazole therapy?
Topics: Adult; Aged; Anti-Ulcer Agents; Female; Gastric Fundus; Humans; Male; Middle Aged; Omeprazole; Polyp | 1998 |
Proton pump inhibitor-associated gastric polyps: a retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics.
Topics: Endoscopy, Digestive System; Enzyme Inhibitors; Female; Gastroesophageal Reflux; Humans; Male; Micro | 1998 |
Fundic gland polyps under omeprazole treatment.
Topics: Anti-Ulcer Agents; Gastric Fundus; Gastroesophageal Reflux; Humans; Omeprazole; Polyps; Stomach Neop | 1999 |
Details of hyperplastic polyps of the stomach shrinking after anti-Helicobacter pylori therapy.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Biomarkers, Tumor; Cell Division; Cyclooxygenase 2; Drug T | 2000 |
Parietal cell protrusions with fundic gland cysts and fundic gland polyps: are they related or simply similar but distinguishable?
Topics: Cysts; Gastric Fundus; Gastric Mucosa; Gastrins; Gastroesophageal Reflux; Humans; Omeprazole; Pariet | 2000 |
Long-term omeprazole treatment and fundic gland polyps: a very authoritative proof against a link?
Topics: Anti-Ulcer Agents; Drug Administration Schedule; Gastric Fundus; Humans; Omeprazole; Polyps; Stomach | 2001 |
Sporadic fundic gland polyps, GERD and omeprazole usage: is there a little piece of information missed?
Topics: Anti-Ulcer Agents; Gastric Fundus; Gastroesophageal Reflux; Humans; Omeprazole; Polyps | 2001 |
Disappearance of both MALT lymphoma and hyperplastic polyps in the stomach after eradication of Helicobacter pylori.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Female; Helicobacter Infectio | 2001 |
Fundic gland polyps are not induced by proton pump inhibitor therapy.
Topics: Enzyme Inhibitors; Female; Gastric Fundus; Gastritis; Helicobacter Infections; Helicobacter pylori; | 2001 |
Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with lansoprazole and Nissen fundoplication: a case report.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Enzyme Inhibitors; Female; Fundoplication; Gastric Fu | 2002 |
Gastric polyposis: onset during long-term therapy with omeprazole.
Topics: Gastroscopy; Humans; Long-Term Care; Omeprazole; Polyps; Stomach Neoplasms | 1992 |
Gastric polyposis: onset during long-term therapy with omeprazole.
Topics: Aged; Aged, 80 and over; Female; Follow-Up Studies; Gastroscopy; Humans; Male; Middle Aged; Omeprazo | 1992 |