Page last updated: 2024-11-01

omeprazole and Pneumonia, Aspiration

omeprazole has been researched along with Pneumonia, Aspiration in 33 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Pneumonia, Aspiration: A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.

Research Excerpts

ExcerptRelevanceReference
"Oral omeprazole 20 mg was given the night before surgery."2.70A study of 13 patients with gastric tube in place after esophageal resection: use of omeprazole to decrease gastric acidity and volume. ( Kishi, Y; Kita, T; Mammoto, T; Yamanaka, Y, 2001)
"The proportion of patients at risk of acid aspiration syndrome according to the traditional criteria (pH < 2."2.69A comparison of rabeprazole, lansoprazole, and ranitidine for improving preoperative gastric fluid property in adults undergoing elective surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Takao, Y, 2000)
"Omeprazole was given orally either as 40 mg on the evening before and 40 mg on the morning of surgery or as 80 mg on the morning of surgery."2.68Comparison of the effect of two dose schedules of oral omeprazole with oral ranitidine on gastric aspirate pH and volume in patients undergoing elective surgery. ( Asbury, AJ; Birrell, H; Bowie, RA; Braid, DP; Gillon, KR; Levack, ID; Marshall, RL; Slawson, KB, 1996)
"Acid aspiration syndrome is still an important cause which contributes to maternal mortality in obstetric anesthesia."2.68Prophylaxis against acid aspiration in regional anesthesia for elective cesarean section: a comparison between oral single-dose ranitidine, famotidine and omeprazole assessed with fiberoptic gastric aspiration. ( Chen, TL; Hsu, HW; Huang, CL; Lin, CJ, 1996)
"Omeprazole 40 mg was given orally the night before and again on the morning of surgery to 30 Asian women scheduled to undergo elective Caesarean section."2.67Effect of oral omeprazole on intragastric pH and volume in women undergoing elective caesarean section. ( Ewart, MC; Gin, T; Oh, TE; Yau, G, 1990)
"Both GERD(gastroesophageal reflux disease) and chronic respiratory disease are common disease in old and the association between GERD and chronic respiratory disease are recently proved in many reports."2.41[Chronic respiratory disease and gastroesophageal reflux]. ( Dobashi, K, 2002)
"Treatment of gastroesophageal reflux disease (GERD) with modern acid-suppressive agents is supposed to be effective and safe."1.30Gastroesophageal reflux disease as a cause of death: analysis of fatal cases under conservative treatment. ( Rantanen, TK; Salo, JA, 1999)
"Omeprazole treatment was well tolerated by the women and Apgar scores and subsequent progress of the babies were acceptable."1.28Effect of single-dose omeprazole on intragastric acidity and volume during obstetric anaesthesia. ( Flynn, RJ; Gillon, KR; Moore, J; Sampaio, M; Wilson, CM, 1989)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's23 (69.70)18.2507
2000's8 (24.24)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dobashi, K1
Memiş, D1
Turan, A1
Karamanlioglu, B1
Saral, P1
Türe, M1
Pamukçu, Z1
Rifas, DC1
Gouda, BB1
Lydon, AM1
Badhe, A1
Shorten, GD1
Hirota, K1
Kudo, M1
Hashimoto, H1
Kushikata, T1
Tripathi, A1
Somwanshi, M1
Singh, B1
Bajaj, P1
Mikawa, K2
Nishina, K2
Maekawa, N2
Asano, M1
Obara, H2
Hett, DA1
Scott, RC1
Risdall, JE1
Vila, P1
Espachs, P1
Echevarria, V1
Garcia, M1
Rincón, R1
Vidal, F1
Gin, T5
Gombar, S1
Kiran, S1
Gupta, M1
Gombar, K1
Chhabra, B1
Boulay, K1
Blanloeil, Y1
Bourveau, M1
Geay, G1
Malinovsky, JM1
Rocke, DA2
Rout, CC2
Gouws, E1
Orr, DA1
Bill, KM1
Gillon, KR3
Wilson, CM2
Fogarty, DJ1
Moore, J2
Bouly, A1
Nathan, N1
Feiss, P1
Davies, PR1
Ogg, TW1
Levack, ID1
Bowie, RA1
Braid, DP1
Asbury, AJ1
Marshall, RL1
Slawson, KB1
Birrell, H1
Stuart, JC1
Kan, AF2
Rowbottom, SJ1
Yau, G3
Lin, CJ1
Huang, CL1
Hsu, HW1
Chen, TL1
Rantanen, TK1
Salo, JA1
Takao, Y1
Shiga, M1
Yamanaka, Y1
Mammoto, T1
Kita, T1
Kishi, Y1
de Silva, KK1
Young, P1
Escolano, F1
Castaño, J1
López, R1
Bisbe, E1
Alcón, A1
Iwasaka, H1
Ito, K1
Kitano, T1
Ikebe, H1
Iwamoto, A1
Oda, S1
Taniguchi, K1
Honda, N1
Okuno, Y1
Oh, TE2
Seveso, M1
Pesci, M1
Lualdi, M1
Vimercati, C1
Battaglia, G1
Cammelli, F1
Evans, J1
Ewart, MC1
Ng Wingtin, L1
Glomaud, D1
Hardy, F1
Phil, S1
Cruickshank, RH1
Morrison, DA1
Bamber, PA1
Nimmo, WS1
Flynn, RJ1
Sampaio, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Observed Volume and pH of Gastric Contents in Patients Undergoing Gynecologic Laparoscopic Surgery During Emergence From General Anesthesia[NCT03672734]100 participants (Anticipated)Observational2018-09-20Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Pneumonia, Aspiration

ArticleYear
[Chronic respiratory disease and gastroesophageal reflux].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:8

    Topics: Asthma; Chronic Disease; Cough; Diet Therapy; Gastroesophageal Reflux; Histamine H2 Antagonists; Hum

2002

Trials

23 trials available for omeprazole and Pneumonia, Aspiration

ArticleYear
The effect of intravenous pantoprazole and ranitidine for improving preoperative gastric fluid properties in adults undergoing elective surgery.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Double-Blin

2003
A comparison of the effects of ranitidine and omeprazole on volume and pH of gastric contents in elective surgical patients.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Ulcer Agents; E

2004
A comparison of intravenous ranitidine and omeprazole on gastric volume and pH in women undergoing emergency caesarean section.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:9

    Topics: Cesarean Section; Double-Blind Method; Emergencies; Female; Gastric Acidity Determination; Histamine

1995
Lansoprazole reduces preoperative gastric fluid acidity and volume in children.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Child; Child, Preschool; Gastric Acidity Determination; Gas

1995
Lansoprazole in the prophylaxis of acid aspiration during elective surgery.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Anesthesia, General; Anti-Ulcer Agents;

1995
Acid aspiration prophylaxis in elective biliary surgery. A comparison of omeprazole and famotidine using manually aided gastric aspiration.
    Anaesthesia, 1994, Volume: 49, Issue:10

    Topics: Adult; Aged; Biliary Tract Surgical Procedures; Elective Surgical Procedures; Famotidine; Female; Ga

1994
Preanaesthetic oral ranitidine, omeprazole and metoclopramide for modifying gastric fluid volume and pH.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:9

    Topics: Administration, Oral; Adult; Anesthesia, General; Double-Blind Method; Gastric Acid; Gastrointestina

1994
Effects of oral ranitidine, famotidine and omeprazole on gastric volume and pH at induction and recovery from general anaesthesia.
    British journal of anaesthesia, 1994, Volume: 73, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anesthesia, General; Elective Surgical Procedures; Famotidine; Ga

1994
Intravenous administration of the proton pump inhibitor omeprazole reduces the risk of acid aspiration at emergency cesarean section.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Double-Blind Method; Emergenc

1994
Effects of omeprazole, with and without metoclopramide, in elective obstetric anaesthesia.
    Anaesthesia, 1993, Volume: 48, Issue:2

    Topics: Administration, Oral; Adult; Anesthesia, Obstetrical; Cesarean Section; Double-Blind Method; Drug Th

1993
Comparison of omeprazole with cimetidine for prophylaxis of acid aspiration in elective surgery.
    European journal of anaesthesiology, 1993, Volume: 10, Issue:3

    Topics: Administration, Oral; Adult; Cimetidine; Double-Blind Method; Dye Dilution Technique; Female; Gastri

1993
Comparison of the effect of two dose schedules of oral omeprazole with oral ranitidine on gastric aspirate pH and volume in patients undergoing elective surgery.
    British journal of anaesthesia, 1996, Volume: 76, Issue:4

    Topics: Adolescent; Adult; Aged; Antacids; Double-Blind Method; Drug Administration Schedule; Female; Gastri

1996
Acid aspiration prophylaxis for emergency Caesarean section.
    Anaesthesia, 1996, Volume: 51, Issue:5

    Topics: Adult; Antacids; Anti-Ulcer Agents; Cesarean Section; Citrates; Citric Acid; Drug Therapy, Combinati

1996
Prophylaxis against acid aspiration in regional anesthesia for elective cesarean section: a comparison between oral single-dose ranitidine, famotidine and omeprazole assessed with fiberoptic gastric aspiration.
    Acta anaesthesiologica Sinica, 1996, Volume: 34, Issue:4

    Topics: Administration, Oral; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Ulcer Agents; Cesarea

1996
A comparison of rabeprazole, lansoprazole, and ranitidine for improving preoperative gastric fluid property in adults undergoing elective surgery.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Double-Blin

2000
A study of 13 patients with gastric tube in place after esophageal resection: use of omeprazole to decrease gastric acidity and volume.
    Journal of clinical anesthesia, 2001, Volume: 13, Issue:5

    Topics: Adult; Aged; Anti-Ulcer Agents; Esophagus; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration;

2001
Effects of omeprazole, ranitidine, famotidine and placebo on gastric secretion in patients undergoing elective surgery.
    British journal of anaesthesia, 1992, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Famotidine; Female; Gastric Mucosa;

1992
[A comparison of the effects of omeprazole with those of ranitidine on intragastric pH and volume in patients for elective surgeries].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:8

    Topics: Gastric Acid; Humans; Omeprazole; Pneumonia, Aspiration; Ranitidine; Surgical Procedures, Operative

1992
A comparison of omeprazole and ranitidine for prophylaxis against aspiration pneumonitis in emergency caesarean section.
    Anaesthesia, 1992, Volume: 47, Issue:2

    Topics: Cesarean Section; Citrates; Citric Acid; Drug Therapy, Combination; Emergencies; Female; Humans; Hyd

1992
[Comparative study of the effects of famotidine and omeprazole in the prevention of the aspiration of gastric contents syndrome in elective surgery].
    Minerva anestesiologica, 1992, Volume: 58, Issue:4

    Topics: Famotidine; Humans; Intraoperative Complications; Omeprazole; Pneumonia, Aspiration

1992
Effect of oral omeprazole on intragastric pH and volume in women undergoing elective caesarean section.
    British journal of anaesthesia, 1990, Volume: 65, Issue:5

    Topics: Administration, Oral; Adult; Anesthesia, General; Anesthesia, Obstetrical; Antacids; Cesarean Sectio

1990
Omeprazole for prophylaxis of acid aspiration in elective surgery.
    Anaesthesia, 1990, Volume: 45, Issue:6

    Topics: Administration, Oral; Adult; Clorazepate Dipotassium; Female; Gastrointestinal Contents; Humans; Hyd

1990
Effect of i.v. omeprazole on the pH and volume of gastric contents before surgery.
    British journal of anaesthesia, 1989, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Double-Blind Method; Female; Gastrointestinal Contents

1989

Other Studies

9 other studies available for omeprazole and Pneumonia, Aspiration

ArticleYear
Adverse events following discharge from the hospital.
    Annals of internal medicine, 2004, Feb-03, Volume: 140, Issue:3

    Topics: Anti-Ulcer Agents; Gastroesophageal Reflux; Health Maintenance Organizations; Humans; Male; Middle A

2004
The efficacy of preanesthetic proton pump inhibitor treatment for patients on long-term H2 antagonist therapy.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Drug Tolera

2005
Intravenous omeprazole before emergency cesarean section.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Cesarean Section; Emergencies; Female; Humans; Injections, Intravenous; Omeprazole; Pneumonia, Aspir

1995
Omeprazole in outpatient surgery.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:3

    Topics: Ambulatory Surgical Procedures; Anesthesia; Humans; Hydrogen-Ion Concentration; Omeprazole; Pneumoni

1993
Omeprazole before emergency caesarean section.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:8

    Topics: Anti-Ulcer Agents; Cesarean Section; Emergencies; Female; Humans; Omeprazole; Pneumonia, Aspiration;

1996
Gastroesophageal reflux disease as a cause of death: analysis of fatal cases under conservative treatment.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Cause of Death; Esophagitis, Peptic; Female; Finland; Gastroesophageal Refl

1999
Protection against aspiration with the Proseal laryngeal mask airway.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anesthesia, General; Female; Follow-Up Studies; Gastr

2002
Acid aspiration prophylaxis.
    Anaesthesia, 1991, Volume: 46, Issue:1

    Topics: Humans; Omeprazole; Pneumonia, Aspiration; Risk Factors

1991
Effect of single-dose omeprazole on intragastric acidity and volume during obstetric anaesthesia.
    Anaesthesia, 1989, Volume: 44, Issue:7

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Gastric Acid; Gastroi

1989