omeprazole has been researched along with Peptic Ulcer Perforation in 19 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Peptic Ulcer Perforation: Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Medical treatment included omeprazole, clarithromycin, and amoxicillin for 7 days followed by omeprazole for 3 weeks for duodenal ulcer and 5 weeks for gastric ulcer." | 5.10 | [Treatment of perforated gastroduodenal ulcer by simple suture followed by Helicobacter pylori eradication]. ( Quandalle, P; Tran, TT, 2002) |
| " The results of the randomized, double-blind, controlled trials show that misoprostol is the only antiulcer drug proven to be effective in the prevention of NSAID-induced gastric and duodenal ulcers as well as for reducing serious upper gastrointestinal complications (perforation and/or haemorrhage)." | 4.79 | Prevention of NSAID-gastropathy. ( Ardizzone, S; Bianchi Porro, G, 1996) |
| "To study the long-term curative effects of suture plus proximal gastric vagotomy (PGV) and suture plus triad-therapy (omeprazole, amoxycillin and flagyl taken orally) for the treatment of duodenal ulcer with acute perforation." | 3.71 | [Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation]. ( Fang, L; Huang, S; Jiang, K; Jiang, X; Lin, N; Pan, W; Wan, Y; Xu, R, 2002) |
| "Eradication of H." | 2.69 | Eradication of Helicobacter pylori prevents recurrence of ulcer after simple closure of duodenal ulcer perforation: randomized controlled trial. ( Chan, AC; Chung, SC; Lam, YH; Lau, JY; Lau, WY; Law, BK; Lee, DW; Ling, TK; Ng, EK; Sung, JJ; To, KF; Yung, MY, 2000) |
| "Primary lymph node gastrinomas are relatively rare in children and, to the best of our knowledge, have not previously been reported at this location." | 1.37 | Long-term follow-up of a child with primary lymph node gastrinoma and Zollinger-Ellison syndrome. ( Nazir, Z, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ono, K | 1 |
| Takeda, M | 1 |
| Makihata, E | 1 |
| Okazaki, J | 1 |
| Nagai, A | 1 |
| El-Nakeeb, A | 1 |
| Fikry, A | 1 |
| Abd El-Hamed, TM | 1 |
| Fouda, el Y | 1 |
| El Awady, S | 1 |
| Youssef, T | 1 |
| Sherief, D | 1 |
| Farid, M | 1 |
| Evseev, MA | 1 |
| Ivakhov, GB | 1 |
| Golovin, RA | 1 |
| Nazir, Z | 1 |
| Valooran, GJ | 1 |
| Kate, V | 1 |
| Jagdish, S | 1 |
| Basu, D | 1 |
| Xu, R | 1 |
| Fang, L | 1 |
| Jiang, X | 1 |
| Wan, Y | 1 |
| Huang, S | 1 |
| Jiang, K | 1 |
| Lin, N | 1 |
| Pan, W | 1 |
| Cherniakevich, SA | 1 |
| Babkova, IV | 1 |
| Mikhalev, AI | 1 |
| Fedele, E | 1 |
| Joneja, JS | 1 |
| Sharma, DB | 1 |
| Sharma, D | 1 |
| Raina, VK | 1 |
| Solomon, LK | 1 |
| Vogiatzis, I | 1 |
| Craig, E | 1 |
| Campbell, FC | 1 |
| Tran, TT | 2 |
| Quandalle, P | 2 |
| Della Beffa, V | 1 |
| Carelli-Basile, A | 1 |
| Leli, R | 1 |
| Fontana, D | 1 |
| McCloy, R | 1 |
| Nair, R | 1 |
| Ardizzone, S | 1 |
| Bianchi Porro, G | 1 |
| Ng, EK | 1 |
| Lam, YH | 1 |
| Sung, JJ | 1 |
| Yung, MY | 1 |
| To, KF | 1 |
| Chan, AC | 1 |
| Lee, DW | 1 |
| Law, BK | 1 |
| Lau, JY | 1 |
| Ling, TK | 1 |
| Lau, WY | 1 |
| Chung, SC | 1 |
| Oncel, M | 1 |
| Kurt, N | 1 |
| Walsh, M | 1 |
| Feliciano, DV | 1 |
| Kolbasa, KP | 1 |
| Lancaster, C | 1 |
| Olafsson, AS | 1 |
| Gilbertson, SK | 1 |
| Robert, A | 1 |
3 reviews available for omeprazole and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Surgery for acid suppression in the 1990s.
Topics: Anti-Ulcer Agents; Female; Gastric Acid; Gastric Mucosa; Helicobacter pylori; Humans; Intestinal Muc | 1993 |
Prevention of NSAID-gastropathy.
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer | 1996 |
Do perforated duodenal ulcers need an acid-decreasing surgical procedure now that omeprazole is available?
Topics: Duodenal Ulcer; Humans; Omentum; Omeprazole; Peptic Ulcer Perforation; Pylorus; Recurrence; Vagotomy | 1992 |
4 trials available for omeprazole and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Effect of Helicobacter pylori eradication on ulcer recurrence after simple closure of perforated duodenal ulcer.
Topics: Adult; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ul | 2009 |
Sequential therapy versus standard triple drug therapy for eradication of Helicobacter pylori in patients with perforated duodenal ulcer following simple closure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; C | 2011 |
Eradication of Helicobacter pylori prevents recurrence of ulcer after simple closure of duodenal ulcer perforation: randomized controlled trial.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; D | 2000 |
[Treatment of perforated gastroduodenal ulcer by simple suture followed by Helicobacter pylori eradication].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; C | 2002 |
12 other studies available for omeprazole and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Perforation of a duodenal ulcer into a non-parasitic liver cyst: a rare case of a penetrate hole blockaded with conservative medical management.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefoperazone; Cysts; Drug Therapy, Combination; Duodenal U | 2014 |
[Antisecretory therapy strategy for patients with bleeding and perforated gastroduodenal ulcers].
Topics: Antacids; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonists; Humans; Omeprazole; Peptic Ulcer | 2009 |
Long-term follow-up of a child with primary lymph node gastrinoma and Zollinger-Ellison syndrome.
Topics: Abdominal Pain; Anti-Ulcer Agents; Child; Combined Modality Therapy; Diarrhea; Duodenal Ulcer; Follo | 2011 |
[Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation].
Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin; Drug Therapy, Combination; Duodenal Ulcer; Fema | 2002 |
[Results of pre- and postoperative treatment of complicated duodenal ulcers with proton pump inhibitors ].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulce | 2002 |
[Is gastric and duodenal ulcer drug-treatable or surgical disease?].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Humans; Lansoprazole; Om | 1997 |
Quality of life after peptic perforation.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid | 2004 |
Hepatic penetration of a single large duodenal ulcer.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Duodenal Ulcer; Fatal Outcome; Humans; Liver Diseases; M | 2005 |
[Long term results of treatment by simple surgical closure of perforated gastroduodenal ulcer followed by eradication of Helicobacter pylori].
Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromyc | 2006 |
[Peptic ulcer: changing indications for gastric resection during the last 15 years].
Topics: Histamine H2 Antagonists; Humans; Omeprazole; Peptic Ulcer; Peptic Ulcer Hemorrhage; Peptic Ulcer Pe | 1994 |
The effectiveness of one-week triple eradication therapy for perforated duodenal ulcer patients treated with simple closure.
Topics: Adult; Amoxicillin; Clarithromycin; Combined Modality Therapy; Dose-Response Relationship, Drug; Dru | 2001 |
Indomethacin-induced gastric antral ulcers in hamsters.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal | 1988 |