omeprazole has been researched along with Pancreatitis in 15 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We present a rare side effect, acute pancreatitis, occurring in a patient who was treated with the proton pump inhibitor omeprazole." | 7.73 | Acute pancreatitis associated with omeprazole. ( Iskandar, SB; Roy, TM; Scruggs, J; Youssef, SS, 2005) |
| "To compare, during strong acid inhibition with omeprazole, the effect of 2 different doses of an enteric-coated pancreatic enzyme preparation on fecal fat excretion and abdominal symptoms in patients with exocrine insufficiency due to chronic pancreatitis (CP)." | 5.12 | Efficacy of lower than standard doses of pancreatic enzyme supplementation therapy during acid inhibition in patients with pancreatic exocrine insufficiency. ( Lamers, CB; Masclee, AA; Symersky, T; Vecht, J, 2006) |
| " MATERIAL OG METHODS: Fifteen healthy subjects and seven patients with chronic pancreatitis were entered in a randomised, double-blind, cross-over study of the exocrine pancreatic function after placebo or omeprazole 80 mg daily for three days." | 5.10 | [Does intake of gastric acid pump inhibitor affect the evaluation of the Lundh test?]. ( Damborg, F; Damborg, SB; Schaffalitzky de Muckadell, OB, 2002) |
| "gov and Cochrane Library from inception to June 30,2021 to retrieve relevant studies using the search strategy: ("Proton pump inhibitors" OR "PPI" OR "PPIs" OR "Omeprazole" OR "Tenatoprazole" OR "Pantoprazole" OR "acid suppression therapy" OR "acid suppression drugs") AND ("pancreatitis" OR "pancreatitides")." | 4.02 | Effectiveness and safety of proton pump inhibitors for treating acute pancreatitis: A protocol for systematic review and meta analysis. ( Cheng, T; Gu, ZH; Han, TY; Liu, BF; Pan, P; Yu, H, 2021) |
| " We present a rare side effect, acute pancreatitis, occurring in a patient who was treated with the proton pump inhibitor omeprazole." | 3.73 | Acute pancreatitis associated with omeprazole. ( Iskandar, SB; Roy, TM; Scruggs, J; Youssef, SS, 2005) |
| "Chronic pancreatitis was alcohol-related in 23 patients, previous surgery was performed in 9, 16 had diabetes and all had steatorrhoea (fat balance > 10g/24h)." | 2.68 | Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis. ( Buedts, K; Cremer, M; Delhaye, M; Gohimont, AC; Meuris, S, 1996) |
| "Acute pancreatitis is a pancreatic inflammation that recognises Salmonella typhi among its aetiological agents." | 1.34 | [Typhoid fever and acute pancreatitis: two cases]. ( Bertuccio, SN; Rombolà, F, 2007) |
| "Omeprazole was administered intraperitoneally, twice a day, for 3 days to the male rats in 0." | 1.31 | Temporary elevation of pancreatic lysosomal enzymes, as a result of the omeprazole-induced peripancreatic inflammation in male Wistar rats. ( Burdan, F; Burski, K; Maciejewski, R; Siezieniewska, Z; Wójtowicz, Z, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 12 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Collen, LV | 1 |
| Mitchell, PD | 1 |
| Fox, VL | 1 |
| Grover, AS | 1 |
| Cheng, T | 1 |
| Liu, BF | 1 |
| Han, TY | 1 |
| Gu, ZH | 1 |
| Pan, P | 1 |
| Yu, H | 1 |
| Iwańczak, B | 1 |
| Stawarski, A | 1 |
| Hutyra, T | 1 |
| Mowszet, K | 1 |
| Iwańczak, F | 1 |
| Wawro, J | 1 |
| Damborg, F | 1 |
| Damborg, SB | 1 |
| Schaffalitzky de Muckadell, OB | 1 |
| Sablin, OA | 1 |
| Ratnikov, VA | 1 |
| Butenko, EV | 1 |
| Pakhomova, IG | 1 |
| Starostin, BD | 1 |
| Kaur, S | 1 |
| Norkina, O | 1 |
| Ziemer, D | 1 |
| Samuelson, LC | 1 |
| De Lisle, RC | 1 |
| Osipenko, MF | 1 |
| Venzhina, IuIu | 1 |
| Youssef, SS | 1 |
| Iskandar, SB | 1 |
| Scruggs, J | 1 |
| Roy, TM | 1 |
| Vecht, J | 1 |
| Symersky, T | 1 |
| Lamers, CB | 1 |
| Masclee, AA | 1 |
| Rombolà, F | 1 |
| Bertuccio, SN | 1 |
| Lai, KC | 1 |
| Cheng, CH | 1 |
| Leung, PS | 1 |
| Delhaye, M | 1 |
| Meuris, S | 1 |
| Gohimont, AC | 1 |
| Buedts, K | 1 |
| Cremer, M | 1 |
| Burdan, F | 1 |
| Siezieniewska, Z | 1 |
| Maciejewski, R | 1 |
| Burski, K | 1 |
| Wójtowicz, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enzyme Substitution in Exocrine Pancreatic Insufficiency; Self Administration Against a Fixed Dose Regimen[NCT01430234] | Phase 4 | 10 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for omeprazole and Pancreatitis
| Article | Year |
|---|---|
[Does intake of gastric acid pump inhibitor affect the evaluation of the Lundh test?].
Topics: Adult; Amylases; Anti-Ulcer Agents; Chronic Disease; Cross-Over Studies; Double-Blind Method; Duoden | 2002 |
[Combination therapy of chronic pancreatitis (double-blind, placebo-controlled, pilot studies)].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Chronic Disease; Double-Blind Method | 2003 |
Efficacy of lower than standard doses of pancreatic enzyme supplementation therapy during acid inhibition in patients with pancreatic exocrine insufficiency.
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Drug Therapy, Combination; Exocrine Panc | 2006 |
Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis.
Topics: Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Exocrine Pancreatic Ins | 1996 |
11 other studies available for omeprazole and Pancreatitis
| Article | Year |
|---|---|
Pancreatitis-Associated Medication Use in Hospitalized Pediatric and Young Adult Patients With Acute Pancreatitis.
Topics: Acute Disease; Child; Hospitalization; Humans; Omeprazole; Pancreatitis; Retrospective Studies; Youn | 2023 |
Effectiveness and safety of proton pump inhibitors for treating acute pancreatitis: A protocol for systematic review and meta analysis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Humans; Meta-Analysis as Topic; Omeprazole; Pancreatitis; P | 2021 |
[Acute pancreatitis as a complication of diagnostic gastroduodenal endoscopy at 10 years old girl--case report].
Topics: Acute Disease; Child; Endoscopy, Gastrointestinal; Female; Humans; Omeprazole; Pancreatitis; Pancrea | 2008 |
[Clinical aspects of using pariet in treating chronic pancreatitis].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Chronic Disease; Enzyme Inhibitors; Humans; | 2002 |
Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas.
Topics: Acids; Amylases; Animals; Chimera; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regula | 2004 |
[Problems of excretory insufficiency of the pancreas].
Topics: Adolescent; Adult; Aged; Famotidine; Feces; Female; Histamine H2 Antagonists; Humans; Male; Middle A | 2004 |
Acute pancreatitis associated with omeprazole.
Topics: Aged, 80 and over; Anti-Ulcer Agents; Enzyme Inhibitors; Humans; Male; Omeprazole; Pancreatitis; Pro | 2005 |
[Typhoid fever and acute pancreatitis: two cases].
Topics: Abdominal Pain; Acute Disease; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Ceftriaxone; Female; | 2007 |
The ghrelin system in acinar cells: localization, expression, and regulation in the exocrine pancreas.
Topics: Achlorhydria; Acute Disease; Animals; Autocrine Communication; Ceruletide; Food Deprivation; Gastric | 2007 |
Temporary elevation of pancreatic lysosomal enzymes, as a result of the omeprazole-induced peripancreatic inflammation in male Wistar rats.
Topics: Acute Disease; Animals; Anti-Ulcer Agents; Lysosomes; Male; Omeprazole; Pancreas; Pancreatitis; Rats | 2000 |
From the Food and Drug Administration.
Topics: Antineoplastic Agents; Biological Products; Gastrinoma; Gastrointestinal Agents; Humans; Investigati | 2002 |