omeprazole has been researched along with Osteogenic Sarcoma in 4 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of methotrexate toxicity potentially induced by a drug interaction between methotrexate and omeprazole in a 25-year-old man with osteosarcoma." | 3.78 | Suspected methotrexate toxicity from omeprazole: a case review of carboxypeptidase G2 use in a methotrexate-experienced patient with methotrexate toxicity and a review of the literature. ( Antonia, SJ; Goetz, D; Haura, EB; McBride, A, 2012) |
| "Omeprazole can inhibit renal elimination of the hydrogen ion and block the active tubular secretion of MTX." | 1.31 | Potential interaction between methotrexate and omeprazole. ( Aldaz, A; Aquerreta, I; Beorlegui, B; Giráldez, J; Ortega, A; Sierrasesúmega, L, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McBride, A | 1 |
| Antonia, SJ | 1 |
| Haura, EB | 1 |
| Goetz, D | 1 |
| Reid, T | 1 |
| Yuen, A | 1 |
| Catolico, M | 1 |
| Carlson, RW | 1 |
| Whelan, J | 1 |
| Hoare, D | 1 |
| Leonard, P | 1 |
| Beorlegui, B | 1 |
| Aldaz, A | 1 |
| Ortega, A | 1 |
| Aquerreta, I | 1 |
| Sierrasesúmega, L | 1 |
| Giráldez, J | 1 |
4 other studies available for omeprazole and Osteogenic Sarcoma
| Article | Year |
|---|---|
Suspected methotrexate toxicity from omeprazole: a case review of carboxypeptidase G2 use in a methotrexate-experienced patient with methotrexate toxicity and a review of the literature.
Topics: Adult; Anti-Ulcer Agents; Drug Interactions; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; O | 2012 |
Impact of omeprazole on the plasma clearance of methotrexate.
Topics: Adult; Bone Neoplasms; Contraindications; Humans; Male; Metabolic Clearance Rate; Methotrexate; Omep | 1993 |
Omeprazole does not alter plasma methotrexate clearance.
Topics: Adult; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans | 1999 |
Potential interaction between methotrexate and omeprazole.
Topics: Child; Drug Interactions; Enzyme Inhibitors; Folic Acid Antagonists; Half-Life; Humans; Inactivation | 2000 |