Page last updated: 2024-11-01

omeprazole and Orphan Diseases

omeprazole has been researched along with Orphan Diseases in 4 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Orphan Diseases: Rare diseases that have not been well studied.

Research Excerpts

ExcerptRelevanceReference
"A physiologically based pharmacokinetic (PBPK) model was used to simulate the impact of elevated levels of interleukin (IL)-6 on the exposure of several orally administered cytochrome P450 (CYP) probe substrates (caffeine, S-warfarin, omeprazole, dextromethorphan, midazolam, and simvastatin)."1.51Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations. ( Ducray, PS; Endo-Tsukude, C; Gardner, I; Gill, KL; Hatley, OJ; Machavaram, KK; Parrott, N; Terao, K, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shibukawa, N1
Ouchi, S1
Wakamatsu, S1
Wakahara, Y1
Tatsumi, N1
Kaneko, A1
Machavaram, KK1
Endo-Tsukude, C1
Terao, K1
Gill, KL1
Hatley, OJ1
Gardner, I1
Parrott, N1
Ducray, PS1
Iwai, H1
Nakamichi, N1
Nakae, K1
Konishi, M1
Inaba, M1
Hoshino, S1
Baba, S1
Amakawa, R1
Kori, M1
Cohen, S1
Levine, A1
Givony, S1
Sokolovskaia-Ziv, N1
Melzer, E1
Granot, E1

Other Studies

4 other studies available for omeprazole and Orphan Diseases

ArticleYear
A Rare Case of Gastric Ulcer Penetrating the Pancreas that was Successfully Managed by Conservative Therapy.
    Internal medicine (Tokyo, Japan), 2017, Sep-01, Volume: 56, Issue:17

    Topics: Anti-Ulcer Agents; Conservative Treatment; Female; Humans; Middle Aged; Omeprazole; Pancreas; Rare D

2017
Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations.
    The AAPS journal, 2019, 03-18, Volume: 21, Issue:3

    Topics: Administration, Oral; Adult; Caffeine; Clinical Trials as Topic; Computer Simulation; Cytochrome P-4

2019
Parotid mucosa-associated lymphoid tissue lymphoma regression after Helicobacter pylori eradication.
    The Laryngoscope, 2009, Volume: 119, Issue:8

    Topics: Amoxicillin; Biopsy, Needle; Clarithromycin; Drug Therapy, Combination; Female; Follow-Up Studies; G

2009
Collagenous gastritis: a rare cause of abdominal pain and iron-deficiency anemia.
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 45, Issue:5

    Topics: Abdominal Pain; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Biopsy; Child; Collagen; Collagen Diseas

2007