Page last updated: 2024-11-01

omeprazole and Nausea

omeprazole has been researched along with Nausea in 17 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
" The patient, who was being treated with digitoxin for heart failure, reported having taken up to four digitoxin tablets (0."7.69[Reversible thrombocytopenia due to digitoxin overdose]. ( Kirch, W; Krappweis, J; Petereit, G; Schentke, KU, 1994)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."6.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
" pylori-positive peptic ulcer received omeprazole 20 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 500 mg twice daily for seven days."5.08One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit? ( Bhutta, AS; Bindel, H; Cunnane, K; Loane, J; O'Connor, HJ, 1997)
" pylori-positive peptic ulcer received lansoprazole 30 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 250 mg twice daily for 5 days."5.08Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? ( Cunnane, K; Kelly, S; Laundon, J; McLoughlin, R; O'Connor, HJ, 1998)
"Although bismuth was both the first drug shown to alter the natural history of peptic ulcer disease and also a constituent of the first very effective eradication regimens, it has been excluded from the newer regimens, despite its safety and low cost, in favour of two antibiotics."5.08Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication. ( Scott, BB, 1998)
" The most common adverse events of headache, diarrhea, and nausea have been reported in fewer than 5% of patients treated with lansoprazole or omeprazole."4.80Safety profile of the proton-pump inhibitors. ( Reilly, JP, 1999)
" The patient, who was being treated with digitoxin for heart failure, reported having taken up to four digitoxin tablets (0."3.69[Reversible thrombocytopenia due to digitoxin overdose]. ( Kirch, W; Krappweis, J; Petereit, G; Schentke, KU, 1994)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."2.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
"Forty of the patients with ESRD (50%) and 48 patients in the control group (60%) were proven to be infected with H pylori."2.70Noninvasive stool antigen assay can effectively screen Helicobacter pylori Infection and assess success of eradication therapy in hemodialysis patients. ( Huang, JJ; Sheu, BS; Wang, YL; Yang, HB, 2001)
"Omeprazole was used in 90% of the patients; lansoprazole, in 7%."1.34Characteristics of children receiving proton pump inhibitors continuously for up to 11 years duration. ( El-Serag, HB; Hassall, E; Kerr, W, 2007)
"Lansoprazole was mostly prescribed in patients with reflux oesophagitis (55."1.30A prospective follow-up study of 5669 users of lansoprazole in daily practice. ( Claessens, A; Heerdink, E; Lamers, CB; Leufkens, H; van Eijk, J, 1997)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (41.18)18.2507
2000's8 (47.06)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Santos Santamarta, F1
Bonoso Criado, R1
Pérez-Millán, AG1
Kloesel, B1
Chandan, VS1
Alexander, GL1
Laheij, RJ1
Van Rossum, LG1
Jansen, JB1
Verheugt, FW1
Lee, KJ1
Demarchi, B1
Demedts, I1
Sifrim, D1
Raeymaekers, P1
Tack, J1
Vakily, M1
Amer, F1
Kukulka, MJ1
Andhivarothai, N1
Hassall, E1
Kerr, W1
El-Serag, HB1
Kori, M1
Cohen, S1
Levine, A1
Givony, S1
Sokolovskaia-Ziv, N1
Melzer, E1
Granot, E1
Harper, MA1
McVeigh, JE1
Thompson, W1
Ardill, JE1
Buchanan, KD1
Krappweis, J1
Petereit, G1
Schentke, KU1
Kirch, W1
Leufkens, H1
Claessens, A1
Heerdink, E1
van Eijk, J1
Lamers, CB1
O'Connor, HJ2
Loane, J1
Bindel, H1
Bhutta, AS1
Cunnane, K2
McLoughlin, R1
Kelly, S1
Laundon, J1
Scott, BB1
Reilly, JP1
Dammann, HG1
Fölsch, UR1
Hahn, EG1
von Kleist, DH1
Klör, HU1
Kirchner, T1
Strobel, S1
Kist, M1
Calvet, X1
Titó, L1
Comet, R1
García, N1
Campo, R1
Brullet, E1
Wang, YL1
Sheu, BS1
Huang, JJ1
Yang, HB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441]Phase 4338 participants (Actual)Interventional2010-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Nausea

ArticleYear
Safety profile of the proton-pump inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Dec-01, Volume: 56, Issue:23 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Diarrhea; Drug Interactions; Gastric Muc

1999

Trials

9 trials available for omeprazole and Nausea

ArticleYear
Proton-pump inhibitor therapy for acetylsalicylic acid associated upper gastrointestinal symptoms: a randomized placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2003, Jul-01, Volume: 18, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents;

2003
A pilot study on duodenal acid exposure and its relationship to symptoms in functional dyspepsia with prominent nausea.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:9

    Topics: Adult; Case-Control Studies; Double-Blind Method; Duodenum; Dyspepsia; Female; Follow-Up Studies; Ga

2004
Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents

2005
One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit?
    Helicobacter, 1997, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Cl

1997
Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough?
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial

1998
Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over;

1998
Eradication of H. pylori with pantoprazole, clarithromycin, and metronidazole in duodenal ulcer patients: a head-to-head comparison between two regimens of different duration.
    Helicobacter, 2000, Volume: 5, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Aged; Anti-Bacterial Agents; Anti-Ul

2000
Four-day, twice daily, quadruple therapy with amoxicillin, clarithromycin, tinidazole and omeprazole to cure Helicobacter pylori infection: a pilot study.
    Helicobacter, 2000, Volume: 5, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Diarrhea; Drug A

2000
Noninvasive stool antigen assay can effectively screen Helicobacter pylori Infection and assess success of eradication therapy in hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Antigens,

2001

Other Studies

7 other studies available for omeprazole and Nausea

ArticleYear
Luetic gastritis: an uncommon cause of gastritis.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:10

    Topics: Abdominal Pain; Adult; Gastritis; Humans; Nausea; Omeprazole; Vomiting

2020
An unusual referral for epigastric pain, nausea, abdominal bloating, diarrhea, and weight loss.
    Gastroenterology, 2012, Volume: 143, Issue:6

    Topics: Abdominal Pain; Adult; Anti-Ulcer Agents; Biopsy; Celiac Disease; Diarrhea; Diet, Gluten-Free; Duode

2012
Characteristics of children receiving proton pump inhibitors continuously for up to 11 years duration.
    The Journal of pediatrics, 2007, Volume: 150, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Distribution; Child; Child, Preschool; Cohort Studies;

2007
Collagenous gastritis: a rare cause of abdominal pain and iron-deficiency anemia.
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 45, Issue:5

    Topics: Abdominal Pain; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Biopsy; Child; Collagen; Collagen Diseas

2007
Successful pregnancy in association with Zollinger-Ellison syndrome.
    American journal of obstetrics and gynecology, 1995, Volume: 173, Issue:3 Pt 1

    Topics: Adult; Anti-Ulcer Agents; Female; Gastric Acid; Gastrins; Humans; Nausea; Omeprazole; Pregnancy; Pre

1995
[Reversible thrombocytopenia due to digitoxin overdose].
    Deutsche medizinische Wochenschrift (1946), 1994, Dec-16, Volume: 119, Issue:50

    Topics: Aged; Digitoxin; Drug Overdose; Female; Gastritis; Gastroscopy; Heart Failure; Humans; Nausea; Omepr

1994
A prospective follow-up study of 5669 users of lansoprazole in daily practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

1997