omeprazole has been researched along with Muscle Relaxation in 9 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to investigate effects of the proton pump inhibitors (PPIs) omeprazole, lansoprazole and pantoprazole, which are currently used for the treatment of hyperacidity and gastro-oesophageal reflux, on the reactivity of the isolated rat lower oesophageal sphincter." | 3.77 | Proton pump inhibitors omeprazole, lansoprazole and pantoprazole induce relaxation in the rat lower oesophageal sphincter. ( Buyukafsar, K; Erenmemisoglu, A; Ozkur, M; Pektas, M; Un, I; Yurtsever, AS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szczesniak, MM | 1 |
| Williams, RB | 1 |
| Brake, HM | 1 |
| Maclean, JC | 1 |
| Cole, IE | 1 |
| Cook, IJ | 1 |
| Yurtsever, AS | 1 |
| Pektas, M | 1 |
| Ozkur, M | 1 |
| Un, I | 1 |
| Erenmemisoglu, A | 1 |
| Buyukafsar, K | 1 |
| Kelicen, P | 1 |
| Pekiner, C | 1 |
| Sarioğlu, Y | 4 |
| Uma, S | 1 |
| Bagcivan, I | 2 |
| Gökçe, G | 2 |
| Ayan, S | 2 |
| Yildirim, S | 3 |
| Saraç, B | 2 |
| Kiliçarslan, H | 1 |
| Aydin, C | 1 |
| Koyuncu, A | 1 |
| Sen, M | 1 |
| Rhoden, KJ | 1 |
| Tallini, G | 1 |
| Douglas, JS | 1 |
| Cucchiara, S | 1 |
| Minella, R | 1 |
| Campanozzi, A | 1 |
| Salvia, G | 1 |
| Borrelli, O | 1 |
| Ciccimarra, E | 1 |
| Emiliano, M | 1 |
| Minhas, S | 1 |
| Cartledge, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Reza Band for the Treatment of Laryngopharyngeal Reflux[NCT03463395] | 0 participants (Actual) | Interventional | 2020-07-31 | Withdrawn (stopped due to Funding for this study has ended and we were unable to enroll any subjects) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for omeprazole and Muscle Relaxation
| Article | Year |
|---|---|
Upregulation of the esophago-UES relaxation response: a possible pathophysiological mechanism in suspected reflux laryngitis.
Topics: Adult; Aged; Anti-Ulcer Agents; Esophageal Sphincter, Upper; Esophagus; Female; Humans; Laryngophary | 2010 |
Effects of omeprazole on mechanisms of gastroesophageal reflux in childhood.
Topics: Anti-Ulcer Agents; Child; Child, Preschool; Controlled Clinical Trials as Topic; Esophagitis, Peptic | 1997 |
7 other studies available for omeprazole and Muscle Relaxation
| Article | Year |
|---|---|
Proton pump inhibitors omeprazole, lansoprazole and pantoprazole induce relaxation in the rat lower oesophageal sphincter.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Angiotensins; Animals; Carbachol; Electric Stimulation; Eso | 2011 |
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitr | 2002 |
Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Disease Models, Animal; Enzyme Inhibitors; H(+)-K( | 2002 |
Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Enzyme Inhibitors; Gallbladder; Guinea Pigs; In Vi | 2003 |
H+-K+ ATPase inhibitors cause relaxation of guinea pig and human airway smooth muscle in vitro.
Topics: Aminoquinolines; Animals; Anti-Ulcer Agents; Enzyme Inhibitors; Guinea Pigs; H(+)-K(+)-Exchanging AT | 1996 |
Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erect | 2001 |
Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum.
Topics: Animals; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Enzyme Inhibitors; Humans; Male; | 2001 |