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omeprazole and Muscle Disorders

omeprazole has been researched along with Muscle Disorders in 5 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Polymyositis occurring in patients treated with omeprazole has been signalled as a possible adverse drug reaction (ADR) by the New Zealand Intensive Medicines Monitoring Programme (IMMP) and the WHO Collaborating Centre for International Drug Monitoring: the Uppsala Monitoring Centre (UMC)."4.83Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors? ( Clark, DW; Strandell, J, 2006)
" Combining epidemiological studies with pharmacokinetic modeling, we detected and evaluated high-dimensional DDIs among 30 frequent drugs."1.48Translational High-Dimensional Drug Interaction Discovery and Validation Using Health Record Databases and Pharmacokinetics Models. ( Chiang, CW; Li, L; Ning, X; Quinney, SK; Shen, L; Wang, L; Wang, X; Zhang, P; Zhang, S, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiang, CW1
Zhang, P1
Wang, X1
Wang, L1
Zhang, S1
Ning, X1
Shen, L1
Quinney, SK1
Li, L1
Tuccori, M1
Giovannoni, S1
Giustini, SE1
Blandizzi, C1
Del Tacca, M1
Clark, DW1
Strandell, J1
Tröger, U1
Stötzel, B1
Martens-Lobenhoffer, J1
Gollnick, H1
Meyer, FP1
Garrote, FJ1
Lacambra, C1
del Ser, T1
García Díaz, B1
Obeso, G1
Solís, J1

Reviews

1 review available for omeprazole and Muscle Disorders

ArticleYear
Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors?
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adverse Drug Reaction Reporting Systems; Enzyme Inhibitors;

2006

Other Studies

4 other studies available for omeprazole and Muscle Disorders

ArticleYear
Translational High-Dimensional Drug Interaction Discovery and Validation Using Health Record Databases and Pharmacokinetics Models.
    Clinical pharmacology and therapeutics, 2018, Volume: 103, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Clonidine; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome

2018
Acute severe myopathy following a single infusion of omeprazole.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:2

    Topics: Acute Disease; Aged; Humans; Infusions, Intravenous; Male; Muscular Diseases; Omeprazole; Proton Pum

2006
Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate.
    BMJ (Clinical research ed.), 2002, Jun-22, Volume: 324, Issue:7352

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Benzimidazoles; Dermatologic Agents; Dru

2002
Subacute myopathy during omeprazole therapy.
    Lancet (London, England), 1992, Sep-12, Volume: 340, Issue:8820

    Topics: Aged; Electromyography; Female; Humans; Muscular Diseases; Omeprazole

1992