Page last updated: 2024-11-01

omeprazole and Muscle Contraction

omeprazole has been researched along with Muscle Contraction in 5 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Cotreatment with omeprazole did not reduce indomethacin-induced intestinal bleeding."1.42Suppression of contractile activity in the small intestine by indomethacin and omeprazole. ( Bhattarai, D; Dial, EJ; Lichtenberger, LM; Phan, TM; Uray, K, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Terranova, C1
Petrella, C1
Improta, G1
Severini, C1
Signore, F1
Damiani, P1
Plotti, F1
Scarpignato, C1
Angioli, R1
Lichtenberger, LM1
Bhattarai, D1
Phan, TM1
Dial, EJ1
Uray, K1
Kelicen, P1
Pekiner, C1
Sarioğlu, Y1
Uma, S1
Yenişehirli, A1
Onur, R1
Okabe, S1
Higaki, E1
Higuchi, T1
Sato, M1
Hara, K1

Other Studies

5 other studies available for omeprazole and Muscle Contraction

ArticleYear
Relaxant effect of proton pump inhibitors on in vitro myometrium from pregnant women.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apamin; Calcium; Dinoprostone; Esomeprazole; Female; Humans

2014
Suppression of contractile activity in the small intestine by indomethacin and omeprazole.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, May-01, Volume: 308, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Enteritis; Gastrointestinal Hemorrhage

2015
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
    Pharmacological research, 2002, Volume: 46, Issue:4

    Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitr

2002
Specific H+/K(+)-ATPase inhibitors decreased contractile responses of isolated rat vas deferens.
    Pharmacological research, 2006, Volume: 54, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adrenergic alpha-Agonists; Animals; Calcium; Dose-Response

2006
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulc

1986