omeprazole has been researched along with Magnesium Deficiency in 19 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Etiologic investigations led to the discovery of Giardiasis lamblia on duodenal biopsies and a long-term treatment with proton pump inhibitors (PPI) (omeprazole followed by esomeprazole), both being recently described as causal factors of hypomagnesemic hypoparathyroidism." | 3.74 | [Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?]. ( Caron, J; Durlach, V; François, M; Lévy-Bohbot, N, 2008) |
| "Two cases of severe hypomagnesaemia in adult long-term users of the PPI omeprazole, presenting with hypocalcaemic seizures." | 3.74 | Severe hypomagnesaemia in long-term users of proton-pump inhibitors. ( Cundy, T; Dissanayake, A, 2008) |
| "The enteral bioavailability of magnesium firmly bound to a fire-proof, inert SiO2-Al2O3 matrix (ground magnesia boats) was studied in magnesium-deficient albino Sprague-Dawley rats, with and without blocking gastric hydrochloric acid secretion with omeprazole." | 1.29 | Erythema formation in magnesium-deficient albino rats. A non-invasive model for the screening of anti-inflammatory agents and oral mineral supplements. ( Abele, C; Classen, CU; Classen, HG; Friedberg, KD; Haubold, W; Schimatschek, HF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Isse, N | 1 |
| Hashimoto, M | 1 |
| Koh, ZY | 1 |
| Lim, SWM | 1 |
| Lim, WS | 1 |
| Semb, S | 1 |
| Helgstrand, F | 1 |
| Hjørne, F | 1 |
| Bytzer, P | 1 |
| van den Berg, S | 1 |
| Scheer, MLJ | 1 |
| Holman, ND | 1 |
| Thongon, N | 1 |
| Penguy, J | 1 |
| Kulwong, S | 1 |
| Khongmueang, K | 1 |
| Thongma, M | 1 |
| Eberhard, J | 1 |
| Macdonald, A | 1 |
| Cundy, T | 2 |
| François, M | 1 |
| Lévy-Bohbot, N | 1 |
| Caron, J | 1 |
| Durlach, V | 1 |
| Shabajee, N | 1 |
| Lamb, EJ | 1 |
| Sturgess, I | 1 |
| Sumathipala, RW | 1 |
| Doornebal, J | 1 |
| Bijlsma, R | 1 |
| Brouwer, RM | 1 |
| Gato Diez, A | 1 |
| Córdoba Soriano, JG | 1 |
| Mora Escudero, I | 1 |
| Fernández-Fernández, FJ | 2 |
| Sesma, P | 2 |
| Caínzos-Romero, T | 2 |
| Ferreira, L | 1 |
| Ferreira-González, L | 1 |
| Callejas Díaz, A | 1 |
| Montero Hernández, E | 1 |
| Gil Navarro, M | 1 |
| Tutor-Ureta, P | 1 |
| Yebra Bango, M | 1 |
| Vargas Núñez, JA | 1 |
| Gutiérrez Macías, A | 1 |
| Ibarmia Lahuerta, J | 1 |
| Alvarez De Castro, M | 1 |
| Lizarralde Palacios, E | 1 |
| Swaminathan, K | 1 |
| Wilson, J | 1 |
| Famularo, G | 1 |
| Minisola, G | 1 |
| Bravi, MC | 1 |
| Colucci, P | 1 |
| Gasbarrone, L | 1 |
| Bai, JP | 1 |
| Hausman, E | 1 |
| Lionberger, R | 1 |
| Zhang, X | 1 |
| Dissanayake, A | 1 |
| Classen, CU | 1 |
| Abele, C | 1 |
| Schimatschek, HF | 1 |
| Friedberg, KD | 1 |
| Classen, HG | 1 |
| Haubold, W | 1 |
19 other studies available for omeprazole and Magnesium Deficiency
| Article | Year |
|---|---|
Omeprazole-induced hypomagnesaemia, causing renal tubular acidosis with hypokalaemia, hypocalcaemia, hyperlactacidaemia and hyperammonaemia.
Topics: Acidosis, Renal Tubular; Aged; Humans; Hyperammonemia; Hyperlactatemia; Hypocalcemia; Hypokalemia; M | 2020 |
An Interesting Case of "Refractory" Hypomagnesemia.
Topics: Aged, 80 and over; Gastric Mucosa; Gastroesophageal Reflux; Humans; Magnesium Deficiency; Male; Omep | 2017 |
Persistent severe hypomagnesemia caused by proton pump inhibitor resolved after laparoscopic fundoplication.
Topics: Administration, Oral; Aged; Fundoplication; Gastroesophageal Reflux; Humans; Infusions, Intravenous; | 2017 |
[Severe hypomagnesaemia due to proton pump inhibitor use].
Topics: Aged; Female; Humans; Magnesium Deficiency; Omeprazole; Proton Pump Inhibitors | 2018 |
Omeprazole suppressed plasma magnesium level and duodenal magnesium absorption in male Sprague-Dawley rats.
Topics: Animals; Anti-Ulcer Agents; Cation Transport Proteins; Claudins; Duodenum; Intestinal Absorption; Ma | 2016 |
Severe proton pump inhibitor-induced hypomagnesaemia in a mother and daughter.
Topics: Aged, 80 and over; Female; Humans; Magnesium Deficiency; Middle Aged; Mothers; Nuclear Family; Omepr | 2017 |
[Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].
Topics: Deglutition Disorders; Duodenum; Esomeprazole; Female; Giardiasis; Humans; Hypocalcemia; Hypoparathy | 2008 |
Omeprazole and refractory hypomagnesaemia.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Chronic Disease; Female; Humans; Hypocalcemia; Hypokalem | 2008 |
[An unknown but potentially serious side effect of proton pump inhibitors: hypomagnesaemia].
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Female; Humans; Hypocalcemia; Hypokalemia; Hypoparathyro | 2009 |
[Severe hypomagnesaemia due to long-term treatment with omeprazole].
Topics: Aged; Enzyme Inhibitors; Humans; Magnesium Deficiency; Male; Omeprazole; Severity of Illness Index | 2011 |
[Hypomagnesemia related to the use of omeprazole with negative result for mutation in the TRPM6 gene].
Topics: Aged; Alcoholism; Esophagitis, Peptic; Famotidine; Histamine H2 Antagonists; Humans; Intestinal Abso | 2011 |
Intermittent use of pantoprazole and famotidine in severe hypomagnesaemia due to omeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonis | 2010 |
[Omeprazole and hypomagnesemia].
Topics: Enzyme Inhibitors; Humans; Magnesium Deficiency; Male; Middle Aged; Omeprazole | 2011 |
[Severe hypomagnesemia related to omeprazole].
Topics: Aged, 80 and over; Anti-Ulcer Agents; Humans; Magnesium Deficiency; Male; Middle Aged; Omeprazole | 2011 |
Elusive cause of hypomagnesaemia.
Topics: Anti-Ulcer Agents; Humans; Hydroxycholecalciferols; Infusions, Intravenous; Magnesium Compounds; Mag | 2011 |
Tetany, hypomagnesemia, and proton-pump inhibitors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biomarkers; Female; Humans; Hypoparathyroidism; Magnesium; | 2012 |
Modeling and simulation of the effect of proton pump inhibitors on magnesium homeostasis. 1. Oral absorption of magnesium.
Topics: Administration, Oral; Computer Simulation; Homeostasis; Humans; Intestinal Absorption; Magnesium; Ma | 2012 |
Severe hypomagnesaemia in long-term users of proton-pump inhibitors.
Topics: Aged; Female; Gastroesophageal Reflux; Humans; Hypocalcemia; Magnesium Deficiency; Male; Middle Aged | 2008 |
Erythema formation in magnesium-deficient albino rats. A non-invasive model for the screening of anti-inflammatory agents and oral mineral supplements.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Cromolyn Sodium; Diet; Disease Models, A | 1993 |