Page last updated: 2024-11-01

omeprazole and Long QT Syndrome

omeprazole has been researched along with Long QT Syndrome in 2 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"To report a case of QT prolongation and syncopal episodes resulting from concomitant use of cisapride and agents known to inhibit its metabolism."1.30Syncopal episodes associated with cisapride and concurrent drugs. ( Gray, VS, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hung, AM1
Hakim, RM1
Gray, VS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development of a Mathematical Model for the Evaluation of the Potassium Kinetic During and After Hemodialysis for the Potassium Profiling in the Dialysate to Prevent Arrhythmias[NCT04563091]6 participants (Anticipated)Interventional2018-11-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Long QT Syndrome

ArticleYear
Dialysate and serum potassium in hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015, Volume: 66, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Azithromycin; Bicarbonates; Black or African American; Calcium; Coronary

2015

Other Studies

1 other study available for omeprazole and Long QT Syndrome

ArticleYear
Syncopal episodes associated with cisapride and concurrent drugs.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:6

    Topics: Accidents, Traffic; Anti-Bacterial Agents; Anti-Ulcer Agents; Cisapride; Clarithromycin; Cytochrome

1998