omeprazole has been researched along with Leucocythaemia in 3 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypericin is a photosensitizing plant pigment from Hypericum perforatum with multiple modes of light-induced biological activities due to production of singlet oxygen and/or excited-state proton transfer with consequent pH drop in the hypericin environment." | 5.31 | Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole. ( Mirossay, A; Mirossay, L; Mojzis, J; Papp, P; Sarisský, M, 2002) |
| "Hypericin is a photosensitizing plant pigment from Hypericum perforatum with multiple modes of light-induced biological activities due to production of singlet oxygen and/or excited-state proton transfer with consequent pH drop in the hypericin environment." | 1.31 | Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole. ( Mirossay, A; Mirossay, L; Mojzis, J; Papp, P; Sarisský, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, WL | 1 |
| Li, DD | 1 |
| Chen, X | 1 |
| Wang, YZ | 1 |
| Xu, JJ | 1 |
| Jiang, ZY | 1 |
| You, QD | 1 |
| Guo, XK | 1 |
| Mirossay, A | 2 |
| Mirossay, L | 2 |
| Sarisský, M | 1 |
| Papp, P | 1 |
| Mojzis, J | 2 |
| Kocisová, E | 1 |
| Radváková, I | 1 |
| Miskovský, P | 1 |
3 other studies available for omeprazole and Leucocythaemia
| Article | Year |
|---|---|
Proton pump inhibitors selectively suppress MLL rearranged leukemia cells via disrupting MLL1-WDR5 protein-protein interaction.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug | 2020 |
Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole.
Topics: Amiloride; Anthracenes; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Interactions; | 2002 |
Hypericin-induced phototoxicity of human leukemic cell line HL-60 is potentiated by omeprazole, an inhibitor of H+K+-ATPase and 5'-(N,N-dimethyl)-amiloride, an inhibitor of Na+/H+ exchanger.
Topics: Amiloride; Anthracenes; Antineoplastic Agents; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Human | 1999 |