Page last updated: 2024-11-01

omeprazole and Intestinal Obstruction

omeprazole has been researched along with Intestinal Obstruction in 6 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

Research Excerpts

ExcerptRelevanceReference
"Randomized patients with available aspirin dosing information in COGENT (N = 3,752) were divided into "low-dose" (≤ 100 mg) and "high-dose" (>100 mg) aspirin groups."2.82Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M, 2016)
"Duodenal hematoma is a rare complication of endoscopic duodenal biopsy that occurs mainly in children or adults with impaired coagulation."1.33Duodenal hematoma following endoscopic duodenal biopsy: a case report and review of the existing literature. ( Araújo-Neto, C; Braga, H; de Andrade Cairo, RC; Diniz-Santos, DR; Paes, IB; Silva, LR, 2006)
"A 46-year-old man with achalasia-like syndrome developed CREST syndrome 4 years later."1.29Achalasia-like syndrome as the first manifestation in a patient with CREST syndrome. ( Berenguer, J; Gálvez, C; Garrigues, V; Ponce, J; Valverde, J, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
García-Romera, Á1
Soto-Darias, I1
González-Hernández, S1
González-Delgado, C1
Bravo-Gutiérrez, A1
Vaduganathan, M1
Bhatt, DL1
Cryer, BL1
Liu, Y1
Hsieh, WH1
Doros, G1
Cohen, M1
Lanas, A1
Schnitzer, TJ1
Shook, TL1
Lapuerta, P1
Goldsmith, MA1
Laine, L1
Cannon, CP1
Balbir-Gurman, A1
Brook, OR1
Chermesh, I1
Braun-Moscovici, Y1
Diniz-Santos, DR1
de Andrade Cairo, RC1
Braga, H1
Araújo-Neto, C1
Paes, IB1
Silva, LR1
Garrigues, V1
Ponce, J1
Gálvez, C1
Valverde, J1
Berenguer, J1
De Francesco, V1
Stoppino, V1
Germano, MP1
Frigerio, P1
De Paolis, PL1
Faleo, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease[NCT00557921]Phase 35,000 participants (Anticipated)Interventional2007-12-31Terminated (stopped due to Terminated by Sponsor)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Intestinal Obstruction

ArticleYear
Pneumatosis cystoides intestinalis in scleroderma-related conditions.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Abdomen, Acute; Adrenal Cortex Hormones; Adult; Aged; Connective Tissue Diseases; Diagnosis, Differe

2012

Trials

1 trial available for omeprazole and Intestinal Obstruction

ArticleYear
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia;

2016

Other Studies

4 other studies available for omeprazole and Intestinal Obstruction

ArticleYear
Small bowel obstruction secondary to enteroenteric fistula: An uncommon complication in chronic NSAID users.
    Cirugia espanola, 2020, Volume: 98, Issue:4

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Female; Huma

2020
Duodenal hematoma following endoscopic duodenal biopsy: a case report and review of the existing literature.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2006, Volume: 20, Issue:1

    Topics: Biopsy; Child; Duodenum; Endoscopy; Enzyme Inhibitors; Female; Hematoma; Humans; Intestinal Obstruct

2006
Achalasia-like syndrome as the first manifestation in a patient with CREST syndrome.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Anti-Ulcer Agents; Cardia; Cisapride; Constipation; CREST Syndrome; Dilatation; Esophageal Achalasia

1996
Ulcer activity but not duodenal stenosis regresses after eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1999, Volume: 29, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Duodenal Diseases; Duodenal Ulcer; Duodenoscopy; Female; Follow-Up Studies

1999