Page last updated: 2024-11-01

omeprazole and Intestinal Diseases

omeprazole has been researched along with Intestinal Diseases in 11 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Li, K1
Cheng, X1
Jin, R1
Han, T1
Li, J1
Satoh, H1
Amagase, K1
Takeuchi, K1
Fujimori, S3
Takahashi, Y2
Tatsuguchi, A3
Sakamoto, C3
Seo, T2
Gudis, K2
Ehara, A2
Kobayashi, T2
Mitsui, K2
Yonezawa, M2
Tanaka, S2
Yamada, Y1
Endo, H1
Higurashi, T1
Hosono, K1
Sakai, E1
Sekino, Y1
Iida, H1
Sakamoto, Y1
Koide, T1
Takahashi, H1
Yoneda, M1
Tokoro, C1
Inamori, M1
Abe, Y1
Nakajima, A1
Mizukami, K1
Murakami, K1
Abe, T1
Inoue, K1
Uchida, M1
Okimoto, T1
Kodama, M1
Fujioka, T1
Maiden, L1
Thjodleifsson, B1
Theodors, A1
Gonzalez, J1
Bjarnason, I1
Scheiman, JM1
Goldstein, JL1
Eisen, GM1
Lewis, B1
Gralnek, IM1
Aisenberg, J1
Bhadra, P1
Berger, MF1
Mazumder, DN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives[NCT03291743]38 participants (Actual)Interventional2017-02-10Terminated (stopped due to Death of Principal Investigator)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for omeprazole and Intestinal Diseases

ArticleYear
Prevention of nonsteroidal anti-inflammatory drug-induced small-intestinal injury by prostaglandin: a pilot randomized controlled trial evaluated by capsule endoscopy.
    Gastrointestinal endoscopy, 2009, Volume: 69, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Diclofenac; Humans; Intestinal Di

2009
Efficacy of Lactobacillus casei treatment on small bowel injury in chronic low-dose aspirin users: a pilot randomized controlled study.
    Journal of gastroenterology, 2011, Volume: 46, Issue:7

    Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dru

2011
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
    World journal of gastroenterology, 2011, Dec-14, Volume: 17, Issue:46

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule E

2011
A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy.
    Gastroenterology, 2005, Volume: 128, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Delayed-Action Preparations; Dicl

2005
What are the effects of cyclooxygenase-2-specific inhibitors on the small bowel?
    Nature clinical practice. Gastroenterology & hepatology, 2005, Volume: 2, Issue:5

    Topics: Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Follow-

2005
Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy.
    Alimentary pharmacology & therapeutics, 2007, May-15, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Celecoxib; Drug

2007

Other Studies

5 other studies available for omeprazole and Intestinal Diseases

ArticleYear
The influence of different proton pump inhibitors and potassium-competitive acid blockers on indomethacin-induced small intestinal injury.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; DNA, Ribo

2022
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Respo

2014
Omeprazole increased small intestinal mucosal injury in two of six disease-free cases evaluated by capsule endoscopy.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2014, Volume: 26, Issue:5

    Topics: Adult; Capsule Endoscopy; Healthy Volunteers; Humans; Intestinal Diseases; Intestinal Mucosa; Intest

2014
Distribution of small intestinal mucosal injuries as a result of NSAID administration.
    European journal of clinical investigation, 2010, Volume: 40, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Diclofenac; Humans; Intestinal Di

2010
Omeprazole and enteric infection.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1994, Volume: 13, Issue:1

    Topics: Duodenal Ulcer; Gram-Negative Bacterial Infections; Humans; Intestinal Diseases; Omeprazole

1994