Page last updated: 2024-11-01

omeprazole and Intellectual Disability

omeprazole has been researched along with Intellectual Disability in 4 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"The therapeutic approach to gastroesophageal reflux disease (GERD) in intellectually disabled individuals has not been studied extensively."5.30Gastroesophageal reflux disease in intellectually disabled individuals: leads for diagnosis and the effect of omeprazole therapy. ( Bohmer, CJ; Devillé, WL; Klinkenberg-Knol, EC; Meuwissen, SG; Niezen-de Boer, MC; Tuynman, HA; Voskuil, JH, 1997)
"Children with symptoms suggesting GERD underwent prolonged 24h intraesophageal pH monitoring and/or upper GI endoscopy with biopsies before and after a 6 months of pharmaceutical (omeprazole) and nutritional (20% increment of daily caloric intake) treatments."1.34Impact of malnutrition on gastrointestinal disorders and gross motor abilities in children with cerebral palsy. ( Campanozzi, A; Capano, G; Del Giudice, E; Miele, E; Militerni, R; Romano, A; Scuccimarra, G; Staiano, A; Strisciuglio, C, 2007)
" Dosage of omeprazole used was 1."1.31Clinical efficacy of proton pump inhibitor therapy in neurologically impaired children with gastroesophageal reflux: prospective study. ( Chan, KH; Chan, YC; Cheung, KM; Ko, CH; Leung, CY; Tse, PW, 2001)
"The therapeutic approach to gastroesophageal reflux disease (GERD) in intellectually disabled individuals has not been studied extensively."1.30Gastroesophageal reflux disease in intellectually disabled individuals: leads for diagnosis and the effect of omeprazole therapy. ( Bohmer, CJ; Devillé, WL; Klinkenberg-Knol, EC; Meuwissen, SG; Niezen-de Boer, MC; Tuynman, HA; Voskuil, JH, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wallace, RA1
Schluter, PJ1
Webb, PM1
Campanozzi, A1
Capano, G1
Miele, E1
Romano, A1
Scuccimarra, G1
Del Giudice, E1
Strisciuglio, C1
Militerni, R1
Staiano, A1
Bohmer, CJ1
Niezen-de Boer, MC1
Klinkenberg-Knol, EC1
Tuynman, HA1
Voskuil, JH1
Devillé, WL1
Meuwissen, SG1
Cheung, KM1
Tse, PW1
Ko, CH1
Chan, YC1
Leung, CY1
Chan, KH1

Other Studies

4 other studies available for omeprazole and Intellectual Disability

ArticleYear
Effects of Helicobacter pylori eradication among adults with intellectual disability.
    Journal of intellectual disability research : JIDR, 2004, Volume: 48, Issue:Pt 7

    Topics: Adult; Amoxicillin; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Heli

2004
Impact of malnutrition on gastrointestinal disorders and gross motor abilities in children with cerebral palsy.
    Brain & development, 2007, Volume: 29, Issue:1

    Topics: Adolescent; Body Mass Index; Cerebral Palsy; Child; Child Nutrition Disorders; Child, Preschool; Enz

2007
Gastroesophageal reflux disease in intellectually disabled individuals: leads for diagnosis and the effect of omeprazole therapy.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:9

    Topics: Adolescent; Adult; Aged; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Child; Child, Preschool; Depres

1997
Clinical efficacy of proton pump inhibitor therapy in neurologically impaired children with gastroesophageal reflux: prospective study.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2001, Volume: 7, Issue:4

    Topics: Child; Child, Preschool; Drug Administration Schedule; Female; Follow-Up Studies; Gastroesophageal R

2001