Page last updated: 2024-11-01

omeprazole and Indigestion

omeprazole has been researched along with Indigestion in 302 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Poliprotect proved noninferior to standard-dose omeprazole in symptomatic patients with heartburn/epigastric burning without erosive esophagitis and gastroduodenal lesions."9.69Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial. ( Annibale, B; Badiali, D; Bassotti, G; Bragazzi, MC; Ciacci, C; Cicala, M; Corazziari, ES; D'Alba, L; D'Ovidio, V; Di Sabatino, A; Gasbarrini, A; Iovino, P; Marazzato, M; Neri, M; Passaretti, S; Radocchia, G; Repici, A; Ribichini, E; Riggio, O; Schippa, S, 2023)
"To compare the efficacy of curcumin versus omeprazole in improving patient reported outcomes in people with dyspepsia."9.69Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial. ( Angsusing, J; Buamahakul, T; Chumsri, C; Khamsai, S; Khongkha, W; Kongkam, P; Kosarussawadee, P; Lopimpisuth, C; Phisalprapa, P; Phutrakool, P; Pongpirul, K; Poonniam, P; Sawanyawisuth, K; Siwamogsatham, S; Sura, T; Teerachaisakul, M; Wanaratna, K, 2023)
"To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo."9.20The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015)
"Patients identified as having acid-related dyspepsia more often developed epigastric pain following acid stimulation during placebo and not during omeprazole treatment."9.13Symptomatic response to blocked and unblocked pentagastrin stimulation in functional dyspepsia. Comparison of responders and non-responders to omeprazole identified in a single-subject trial model. ( Bytzer, P; Madsen, LG, 2008)
"One hundred and nineteen patients with functional dyspepsia completed a 12-day, double-blind random-starting-day trial with an initial placebo run-in followed by switch to omeprazole on a randomized and blinded day (between days 5 and 9) with active treatment continuing for the rest of the trial."9.11Reproducibility of a symptom response to omeprazole therapy in functional dyspepsia evaluated by a random-starting-day trial design. ( Bytzer, P; Madsen, LG, 2004)
"To evaluate the efficacy of different doses of lansoprazole for the treatment of functional dyspepsia in Chinese patients."9.10Double blind, randomised, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients. ( Fung, FM; Hu, WH; Hung, WK; Lai, KC; Lam, SK; Szeto, ML; Tong, TS; Wong, BC; Wong, WM; Yee, YK; Yip, AW; Yuen, MF, 2002)
"To compare the efficacy of a "Helicobacter pylori test and treat" strategy with that of an empirical trial of omeprazole in the non-endoscopic management by empirical prescribing of young patients with dyspepsia."9.10Empirical prescribing for dyspepsia: randomised controlled trial of test and treat versus omeprazole treatment. ( Balzano, A; de Nucci, C; Manes, G; Menchise, A, 2003)
"Both sucralfate and rabeprazole therapies are effective treatment options in the patients with alkaline gastritis when compared with observation."9.10Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment. ( Cammarota, G; Candelli, M; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Nista, EC; Santarelli, L, 2003)
"The aim of this study was to compare the effect of a combination of lansoprazole, clarithromycin, and amoxicillin (LCA) versus placebo on the severity of symptoms in functional dyspepsia patients who were positive for Helicobacter pylori (H."9.10Absence of symptomatic benefit of lansoprazole, clarithromycin, and amoxicillin triple therapy in eradication of Helicobacter pylori positive, functional (nonulcer) dyspepsia. ( Cohen, L; Fedorak, RN; Lambert, J; Vanjaka, A; Veldhuyzen van Zanten, S, 2003)
"In the intention-to-treat population, a complete relief of overall primary symptoms of dyspepsia was achieved after 2 weeks in 53% of patients receiving lansoprazole and in 41% of patients receiving omeprazole (P = 0."9.09Low-dose lansoprazole provides greater relief of heartburn and epigastric pain than low-dose omeprazole in patients with acid-related dyspepsia. ( Crouch, SL; Jones, R, 1999)
"To evaluate the efficacy of 1-week triple therapy with omeprazole, clarithromycin,and tinidazole (OCT) in Helicobacter pylori-positive older patients with dyspepsia."9.09The efficacy of omeprazole-based short-term triple therapy in Helicobacter pylori-positive older patients with dyspepsia. ( Arber, N; Brill, S; Halpern, Z; Konikoff, FM; Moshkowitz, M; Reif, S, 1999)
" pylori-positive patients with non-ulcer dyspepsia were treated for 7 days with clarithromycin 500 mg b."9.09Double vs. single dose of pantoprazole in combination with clarithromycin and amoxycillin for 7 days, in eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. ( De Mascarel, A; Lamouliatte, H; Megraud, F; Samoyeau, R, 1999)
"The effect of omeprazole therapy in dyspepsia is unpredictable."9.09Which dyspepsia patients will benefit from omeprazole treatment? Analysis of a Danish multicenter trial. ( Christensen, E; Meineche-Schmidt, V, 2000)
"A total of 59 consecutive Helicobacter pylori infected non-ulcer dyspepsia patients were randomly selected to receive either one of two triple therapy regimens, including metronidazole, amoxycillin plus ranitidine bismuth citrate (RAM group) or omeprazole (OAM group)."9.09Ranitidine bismuth citrate or omeprazole-based triple therapy for Helicobacter pylori eradication in Helicobacter pylori-infected non-ulcer dyspepsia. ( Chuang, CH; Lin, XZ; Sheu, BS; Wu, JJ; Yang, HB, 2001)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."9.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
"Helicobacter pylori-positive patients (n=323) with non-ulcer dyspepsia were randomized to receive one of four 1-week regimens consisting of omeprazole, 20 mg b."9.09A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. ( Barthélemy, P; Caekaert, A; Fléjou, JF; Laurent, J; Mégraud, F, 2001)
"Patients with a history of dyspepsia or uncomplicated peptic ulcer disease and with a need for continuous NSAID treatment were randomized to receive either 20 mg omeprazole once daily or placebo."9.08Prevention of peptic ulcer and dyspeptic symptoms with omeprazole in patients receiving continuous non-steroidal anti-inflammatory drug therapy. A Nordic multicentre study. ( Anker-Hansen, O; Carling, L; Ekström, P; Lundegårdh, G; Thorhallsson, E; Unge, P; Wetterhus, S; Wingren, PE, 1996)
"To examine dyspepsia symptom relief over 16 weeks and compare an omeprazole clinical management strategy with a commonly used combination of antacid-alginate followed by H2-antagonist."9.08The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected]. ( Evans, WM; Mason, I; Millar, LJ; Sheikh, RR; Taylor, MD; Todd, PL; Turbitt, ML, 1998)
"Patients (n = 1262) with a clinical diagnosis of functional dyspepsia (persistent or recurrent epigastric pain or discomfort for at least 1 month and a normal upper gastrointestinal endoscopy) were randomized to receive omeprazole 20 mg, 10 mg or identical placebo, for 4 weeks."9.08Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies). ( Duckworth, M; Kordecki, H; Meineche-Schmidt, V; Pap, A; Paré, P; Räisänen, P; Schmid, V; Talley, NJ, 1998)
"Treatment with omeprazole provides superior symptom relief compared to ranitidine, cisapride, and placebo in the treatment of H."6.71A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study. ( Armstrong, D; Barkun, A; Chiba, N; Escobedo, S; Lee, J; Sinclair, P; Smyth, S; Thomson, A; Veldhuyzen van Zanten, SJ, 2005)
"Symptoms of gastro-oesophageal reflux are common, and currently available methods for diagnosing reflux disease are expensive and uncomfortable for the patient."6.69One-week omeprazole treatment in the diagnosis of gastro-oesophageal reflux disease. ( Bengtsson, L; Hernqvist, H; Johnsson, F; Solhaug, JH; Weywadt, L, 1998)
"Poliprotect proved noninferior to standard-dose omeprazole in symptomatic patients with heartburn/epigastric burning without erosive esophagitis and gastroduodenal lesions."5.69Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial. ( Annibale, B; Badiali, D; Bassotti, G; Bragazzi, MC; Ciacci, C; Cicala, M; Corazziari, ES; D'Alba, L; D'Ovidio, V; Di Sabatino, A; Gasbarrini, A; Iovino, P; Marazzato, M; Neri, M; Passaretti, S; Radocchia, G; Repici, A; Ribichini, E; Riggio, O; Schippa, S, 2023)
"To compare the efficacy of curcumin versus omeprazole in improving patient reported outcomes in people with dyspepsia."5.69Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial. ( Angsusing, J; Buamahakul, T; Chumsri, C; Khamsai, S; Khongkha, W; Kongkam, P; Kosarussawadee, P; Lopimpisuth, C; Phisalprapa, P; Phutrakool, P; Pongpirul, K; Poonniam, P; Sawanyawisuth, K; Siwamogsatham, S; Sura, T; Teerachaisakul, M; Wanaratna, K, 2023)
"Acute interstitial nephritis is an uncommon but important cause of acute renal failure."5.33Rabeprazole-induced acute interstitial nephritis. ( Coleman, PL; Geevasinga, N; Roger, SD, 2005)
"When omeprazole was re-started she developed fever and acute renal failure, which again settled quickly on discontinuation of omeprazole."5.30Pyrexia, anaemia and acute renal failure secondary to omeprazole. ( Arnold, IR; Ferner, RE; Landray, MJ; Ringrose, T, 1998)
"To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo."5.20The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015)
"Helicobacter pylori -positive adult patients with functional dyspepsia meeting the Rome III International Consensus criteria were randomly assigned to receive omeprazole, amoxicillin trihydrate, and clarithromycin, or omeprazole plus placebo for 10 days."5.15Helicobacter pylori eradication in functional dyspepsia: HEROES trial. ( Berwanger, O; Birkhan, OA; Bressel, M; Colombo, Bda S; Dahmer, FD; De Bona, LR; Edelweiss, MI; Folador, L; Francesconi, CF; Grando, E; Guerrieri, PP; Heck, R; Hocevar de Moura, B; Katz, N; Lunkes, RP; Marini, SS; Mazzoleni, F; Mazzoleni, LE; Milbradt, TC; Molina, CG; Prolla, JC; Rauber, J; Renck, LB; Sander, GB; Spindler, BM; Uchoa, DM; Von Reisswitz, PS, 2011)
"Patients identified as having acid-related dyspepsia more often developed epigastric pain following acid stimulation during placebo and not during omeprazole treatment."5.13Symptomatic response to blocked and unblocked pentagastrin stimulation in functional dyspepsia. Comparison of responders and non-responders to omeprazole identified in a single-subject trial model. ( Bytzer, P; Madsen, LG, 2008)
"Ninety-one Helicobacter pylori-positive patients with nonulcer dyspepsia were randomized to receive either lansoprazole, amoxicillin, and clarithromycin or lansoprazole and placebo."5.12Clinical outcomes of eradication of Helicobacter pylori in nonulcer dyspepsia in a population with a high prevalence of infection: results of a 12-month randomized, double blind, placebo-controlled study. ( Barros, SG; Cartell, A; Edelweiss, MI; Francesconi, CF; Fritscher, LG; Mazzoleni, LE; Ott, EA; Polanczyk, CA; Prolla, JC; Rivero, LF; Sander, GB; Theil, AL; Uchôa, DM; Wortmann, AC, 2006)
"Adult Helicobacter pylori-positive patients by 13C-urea breath test with uninvestigated dyspepsia symptoms were randomized to 1-week eradication treatment with omeprazole, metronidazole and clarithromycin (OMC) vs."5.11Economic evaluation of Helicobacter pylori eradication in the CADET-Hp randomized controlled trial of H. pylori-positive primary care patients with uninvestigated dyspepsia. ( Armstrong, D; Barkun, A; Chiba, N; Escobedo, S; Grace, E; Lee, J; Sinclair, P; Thomson, AB; Veldhuyzen Van Zanten, SJ, 2004)
"One hundred and nineteen patients with functional dyspepsia completed a 12-day, double-blind random-starting-day trial with an initial placebo run-in followed by switch to omeprazole on a randomized and blinded day (between days 5 and 9) with active treatment continuing for the rest of the trial."5.11Reproducibility of a symptom response to omeprazole therapy in functional dyspepsia evaluated by a random-starting-day trial design. ( Bytzer, P; Madsen, LG, 2004)
"Symptoms described with the words 'burning' or 'sour' and patients with reflux-like dyspepsia demonstrated high response to omeprazole treatment, whereas patients with abdominal pain or ulcer-like dyspepsia responded unpredictably to omeprazole."5.11Classification of dyspepsia and response to treatment with proton-pump inhibitors. ( Meineche-Schmidt, V, 2004)
"Heartburn-dominant uninvestigated dyspepsia patients from 46 primary care centres were randomized to one of two active treatment strategies: omeprazole 20 mg daily (proton pump inhibitor-start) or ranitidine 150 mg bid (H2-receptor antagonist-start) for the first 4-8 weeks, stepping up to omeprazole 40 or 20 mg daily, respectively, for 4-8 weeks for persistent symptoms."5.11Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study. ( Armstrong, D; Barkun, AN; Chakraborty, B; Chiba, N; Sinclair, P; Smyth, S; Thomson, AB; Veldhuyzen van Zanten, SJ; White, RJ, 2005)
" pylori-positive functional dyspepsia were randomized to receive pantoprazole 40 mg b."5.11Recent success of pantoprazole -or lansoprazole- based clarithromycin plus amoxicillin treatment in the eradication of Helicobacter pylori. ( Ateş, Y; Bağci, S; Ciğerim, M; Dağalp, K; Kadayifçi, A; Karslioğlu, Y; Savaş, MC; Uygun, A; Yeşilova, Z, 2004)
"Celecoxib was as effective as lansoprazole co-therapy in the prevention of recurrences of ulcer complications in subjects with a history of NSAID-related complicated peptic ulcers."5.11Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications. ( Chan, AO; Chu, KM; Hu, WH; Hui, WM; Lai, KC; Lam, SK; Wong, BC; Wong, J; Wong, WM, 2005)
"To evaluate the efficacy of different doses of lansoprazole for the treatment of functional dyspepsia in Chinese patients."5.10Double blind, randomised, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients. ( Fung, FM; Hu, WH; Hung, WK; Lai, KC; Lam, SK; Szeto, ML; Tong, TS; Wong, BC; Wong, WM; Yee, YK; Yip, AW; Yuen, MF, 2002)
" pylori positive patients with non-ulcer dyspepsia were randomised to one of the following four treatment groups: omeprazole 20 mg + clarithromycin 500 mg + amoxycillin 1000 mg (OCA); ranitidine bismuth citrate 400 mg + clarithromycin 500 mg + amoxycillin 1000 mg (RBCCA); omeprazole 20 mg + clarithromycin 500 mg + metronidazole 500 mg (OCM); ranitidine bismuth citrate 400 mg + clarithromycin 500 mg + metronidazole 500 mg (RBCCM)."5.10The impact of primary antibiotic resistance on the efficacy of ranitidine bismuth citrate- vs. omeprazole-based one-week triple therapies in H. pylori eradication--a randomised controlled trial. ( Bago, J; Bevanda, M; Bilić, A; Halle, ZB; Jandrić, D; Kućisec, N; Strinić, D; Tomić, M, 2002)
"We conducted a double blind, randomized, placebo-controlled trial in which patients with uninvestigated dyspepsia were randomized to a 6-wk course of omeprazole 20 mg p."5.10A double blind, randomized, placebo-controlled trial of proton pump inhibitor therapy in patients with uninvestigated dyspepsia. ( Ambriz, E; Huang, I; Menke, T; Rabeneck, L; Souchek, J; Wray, N; Wristers, K, 2002)
"The study was a secondary analysis of data obtained from a double-blind, randomized placebo-controlled trial, evaluating a 6-week course of omeprazole versus placebo in 140 patients with uninvestigated dyspepsia who were followed for up to 1 year."5.10Impact of upper endoscopy on satisfaction in patients with previously uninvestigated dyspepsia. ( Ambriz, E; Rabeneck, L; Souchek, J; Wristers, K, 2003)
" pylori-positive patients with non-ulcer dyspepsia received 1-week omeprazole-based triple therapy, or omeprazole plus placebos."5.10Clinical and pathological implications of IgG antibody responses to Helicobacter pylori and its virulence factors in non-ulcer dyspepsia. ( Blum, AL; Bolling-Sternevald, E; Mitchell, HM; O'Morain, CA; Stolte, M; Talley, NJ; Xia, HH, 2003)
"To compare the efficacy of a "Helicobacter pylori test and treat" strategy with that of an empirical trial of omeprazole in the non-endoscopic management by empirical prescribing of young patients with dyspepsia."5.10Empirical prescribing for dyspepsia: randomised controlled trial of test and treat versus omeprazole treatment. ( Balzano, A; de Nucci, C; Manes, G; Menchise, A, 2003)
"Data were pooled on patients (n = 826) with a diagnosis of functional dyspepsia from two placebo-controlled trials who were treated with omeprazole, 10 or 20 mg once daily, for 4 weeks."5.10Is it possible to predict treatment response to a proton pump inhibitor in functional dyspepsia? ( Bolling-Sternevald, E; Glise, H; Junghard, O; Lauritsen, K; Talley, NJ, 2003)
"Both sucralfate and rabeprazole therapies are effective treatment options in the patients with alkaline gastritis when compared with observation."5.10Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment. ( Cammarota, G; Candelli, M; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Nista, EC; Santarelli, L, 2003)
"Eight hundred patients with functional dyspepsia were randomized to receive double-blind treatment with twice-daily 30 mg lansoprazole, 1000 mg amoxicillin and 500 mg clarithromycin for 7 days (L30AC), twice-daily 15 mg lansoprazole, 1000 mg amoxicillin and 500 mg clarithromycin for 7 days (L15AC), or once-daily 15 mg lansoprazole for 14 days (LP)."5.10Helicobacter pylori eradication is beneficial in the treatment of functional dyspepsia. ( Demleitner, K; Fischbach, W; Fuchs, W; Layer, P; Leodolter, A; Malfertheiner, P; MOssner, J; Stolte, M, 2003)
"The aim of this study was to compare the effect of a combination of lansoprazole, clarithromycin, and amoxicillin (LCA) versus placebo on the severity of symptoms in functional dyspepsia patients who were positive for Helicobacter pylori (H."5.10Absence of symptomatic benefit of lansoprazole, clarithromycin, and amoxicillin triple therapy in eradication of Helicobacter pylori positive, functional (nonulcer) dyspepsia. ( Cohen, L; Fedorak, RN; Lambert, J; Vanjaka, A; Veldhuyzen van Zanten, S, 2003)
"To study whether prophylaxis with lansoprazole could prevent relapse of ulcers after eradication of Helicobacter pylori in patients with NSAID-related peptic ulcers."5.10Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users--a randomized trial. ( Chan, CK; Chan, OO; Chu, KM; Hu, HC; Hui, WM; Kwok, KF; Lai, KC; Lam, SK; Wong, BC; Wong, WM, 2003)
"In a randomized, multicentre, prospective study, a total of 352 patients with duodenal ulcer or non-ulcer dyspepsia were randomly divided into three groups according to the administered regimen: OAC250 group (omeprazole, 20 mg, amoxicillin, 1000 mg, and clarithromycin, 250 mg), OAC500 group (omeprazole, 20 mg, amoxicillin, 1000 mg, and clarithromycin, 500 mg) and OTC group (omeprazole, 20 mg, tinidazole, 500 mg, and clarithromycin, 500 mg)."5.10Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication. ( Ahn, DS; Choi, IJ; Choi, KW; Chung, IS; Chung, JM; Hong, WS; Jung, HC; Kim, JH; Lee, SI; Rew, JS; Rhee, JC; Yang, US, 2002)
"In the intention-to-treat population, a complete relief of overall primary symptoms of dyspepsia was achieved after 2 weeks in 53% of patients receiving lansoprazole and in 41% of patients receiving omeprazole (P = 0."5.09Low-dose lansoprazole provides greater relief of heartburn and epigastric pain than low-dose omeprazole in patients with acid-related dyspepsia. ( Crouch, SL; Jones, R, 1999)
"Helicobacter pylori-positive patients (224) with peptic ulcer disease or non-ulcer dyspepsia were randomized to receive one of three different omeprazole or lansoprazole-amoxycillin-clarithromycin (PPI/AC) regimens for 7 days: (1) OAC 20 regimen (n = 76), omeprazole (OPZ) 20 mg daily, amoxycillin (AMOX) 500 mg t."5.09Efficacy of 1 week omeprazole or lansoprazole-amoxycillin-clarithromycin therapy for Helicobacter pylori infection in the Japanese population. ( Miwa, H; Murai, T; Nagahara, A; Ohkura, R; Sato, K; Sato, N; Shimizu, H; Watanabe, S, 1999)
" pylori-positive patients with endoscopically defined peptic ulcer [DU (n = 65), GU (n = 12)] or non-ulcer dyspepsia (NUD, n = 43) were randomized to receive a 1-week course of twice daily omeprazole 20 mg, clarithromycin 250 mg and either metronidazole 400 mg (OCM) or tinidazole 500 mg (OCT) in a double-blind fashion."5.09Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia. ( Goddard, AF; Lawes, S; Logan, RP; Spiller, RC, 1999)
"To evaluate the efficacy of 1-week triple therapy with omeprazole, clarithromycin,and tinidazole (OCT) in Helicobacter pylori-positive older patients with dyspepsia."5.09The efficacy of omeprazole-based short-term triple therapy in Helicobacter pylori-positive older patients with dyspepsia. ( Arber, N; Brill, S; Halpern, Z; Konikoff, FM; Moshkowitz, M; Reif, S, 1999)
"Patients with functional dyspepsia from Denmark, France, Germany, The Netherlands, Hungary, and Poland (n = 567 (215 men), 18-80 years old) were followed up for 3 months after a 4-week treatment trial with omeprazole (20 mg or 10 mg) or placebo."5.09Impact of functional dyspepsia on quality of life and health care consumption after cessation of antisecretory treatment. A multicentre 3-month follow-up study. ( Bolling-Sternevald, E; Kordecki, H; Meineche-Schmidt, V; Ohlsson, L; Pap, A; Schmid, V; Talley, NJ; Wahlqvist, P; Wiklund, I, 1999)
" pylori-infected patients with nonulcer dyspepsia to receive twice-daily treatment with 20 mg of omeprazole, 1000 mg of amoxicillin, and 500 mg of clarithromycin for 14 days and 167 such patients to receive identical-appearing placebos; all patients were then followed through regular visits for 12 months."5.09Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia. ( Ballard, ED; Fennerty, MB; Talley, NJ; Vakil, N, 1999)
" pylori-positive patients with non-ulcer dyspepsia were treated for 7 days with clarithromycin 500 mg b."5.09Double vs. single dose of pantoprazole in combination with clarithromycin and amoxycillin for 7 days, in eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. ( De Mascarel, A; Lamouliatte, H; Megraud, F; Samoyeau, R, 1999)
"After a complete diagnostic workup, 792 patients with functional dyspepsia unresponsive to one week of low dose antacid treatment were randomised to two weeks of treatment with placebo, ranitidine 150 mg, omeprazole 10 mg, or omeprazole 20 mg daily."5.09Short course acid suppressive treatment for patients with functional dyspepsia: results depend on Helicobacter pylori status. The Frosch Study Group. ( Arnold, R; Blum, AL; Fischer, M; Koelz, HR; Stolte, M, 2000)
"The effect of omeprazole therapy in dyspepsia is unpredictable."5.09Which dyspepsia patients will benefit from omeprazole treatment? Analysis of a Danish multicenter trial. ( Christensen, E; Meineche-Schmidt, V, 2000)
" pylori who had functional dyspepsia were randomly assigned to 7 days of treatment with a lansoprazole-based triple therapy or placebo and then followed for 1 year."5.09Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia. ( Chan, HH; Chen, W; Cheng, JS; Chien, EJ; Hsu, PI; Hsu, PN; Ku, MK; Lai, KH; Lin, CK; Lo, CC; Lo, GH; Peng, NJ; Tseng, HH, 2001)
"A total of 59 consecutive Helicobacter pylori infected non-ulcer dyspepsia patients were randomly selected to receive either one of two triple therapy regimens, including metronidazole, amoxycillin plus ranitidine bismuth citrate (RAM group) or omeprazole (OAM group)."5.09Ranitidine bismuth citrate or omeprazole-based triple therapy for Helicobacter pylori eradication in Helicobacter pylori-infected non-ulcer dyspepsia. ( Chuang, CH; Lin, XZ; Sheu, BS; Wu, JJ; Yang, HB, 2001)
"Non-ulcer dyspepsia patients (n=199), with a normal upper endoscopy and a positive (13)C-urea breath test (UBT) were randomly assigned to either pantoprazole, clarithromycin and metronidazole (PCM) or pantoprazole, clarithromycin and eicosapen (PCE) for 7 days."5.09Fish oil (Eicosapen) is less effective than metronidazole, in combination with pantoprazole and clarithromycin, for Helicobacter pylori eradication. ( Drewe, J; Geiser, HR; Meier, R; Wettstein, A, 2001)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."5.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
" Ulcer-like dyspepsia seemed to benefit from omeprazole."5.09A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome. ( Buskens, E; de Wit, NJ; Lewin van den Broek, NT; Numans, ME; Smout, AJ; Verheij, TJ, 2001)
"Helicobacter pylori-positive patients (n=323) with non-ulcer dyspepsia were randomized to receive one of four 1-week regimens consisting of omeprazole, 20 mg b."5.09A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. ( Barthélemy, P; Caekaert, A; Fléjou, JF; Laurent, J; Mégraud, F, 2001)
"In functional dyspepsia, pantoprazole influenced the acid-induced duodenogastric feedback mechanism, but not the impaired duodenal motor response."5.09Effect of inhibition of gastric acid secretion on antropyloroduodenal motor activity and duodenal acid hypersensitivity in functional dyspepsia. ( Samsom, M; Schwartz, MP; Smout, AJ; Van Berge Henegouwen, GP, 2001)
"pylori positive (histology and/or culture) ulcer disease (n = 17; acute ulcer: n = 11) or functional dyspepsia (n = 13) were treated over one week with pantoprazole 40 mg bd, clarithromycin 250 mg bd and metronidazole 400 mg bd."5.08[Short-term triple therapy with pantoprazole, clarithromycin and metronidazole in eradication of Helicobacter pylori]. ( Becker, T; Börsch, G; Labenz, J; Peitz, U; Stolte, M; Tillenburg, B, 1995)
" pylori infection and peptic ulcer disease (n = 64) or functional dyspepsia (n = 16), with similar demographic and clinical characteristics, were treated for 1 week with either omeprazole 20 mg once in the morning and clarithromycin 250 mg and metronidazole 400 mg twice daily (OCM; n = 40) or with omeprazole 20 mg once in the morning and clarithromycin 250 mg and tetracycline 500 mg twice daily (OCT; n = 40)."5.08One-week low-dose triple therapy for the eradication of Helicobacter pylori infection. ( Becker, T; Börsch, G; Labenz, J; Rühl, GH; Sollböhmer, M; Stolte, M; Tillenburg, B, 1995)
"We report the results of seven therapeutic trials combining omeprazole, clarithromycin, amoxycillin, colloidal bismuth subcitrate and tinidazole in 198 patients (peptic ulcer disease/non-ulcerative dyspepsia, 137/61) to eradicate H."5.08Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients. ( Buset, M; De Koster, E; Deltenre, M; Jonas, C; Otero, J; van Gossum, M, 1995)
" Those patients with active duodenal ulcers present at endoscopy were given omeprazole 20 mg nocte for a further 21 days."5.08A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate. ( Broadbent, A; Chambers, S; Gould, SR; Mistry, R; Ranganath, L; Weldon, MJ, 1996)
"Patients with a history of dyspepsia or uncomplicated peptic ulcer disease and with a need for continuous NSAID treatment were randomized to receive either 20 mg omeprazole once daily or placebo."5.08Prevention of peptic ulcer and dyspeptic symptoms with omeprazole in patients receiving continuous non-steroidal anti-inflammatory drug therapy. A Nordic multicentre study. ( Anker-Hansen, O; Carling, L; Ekström, P; Lundegårdh, G; Thorhallsson, E; Unge, P; Wetterhus, S; Wingren, PE, 1996)
"Patients with active HP infection and peptic ulcer, a history of peptic ulcer, or nonulcer dyspepsia were randomized to either lansoprazole 30 mg b."5.08Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. ( Barnett, JL; Chey, WD; DelValle, J; Elta, GH; Fisher, L; Hasler, WL; Nostrant, T; Scheiman, JM, 1997)
"In a prospective study, 113 patients with peptic ulcer (n = 36) or non-ulcer dyspepsia (n = 77) were randomized to receive 1-wk treatment, composed of omeprazole 20 mg b."5.08Omeprazole plus clarithromycin and either tinidazole or tetracycline for Helicobacter pylori infection: a randomized prospective study. ( Attili, AF; Diana, F; Pugliano, F; Rinaldi, V; Zullo, A, 1997)
"To examine dyspepsia symptom relief over 16 weeks and compare an omeprazole clinical management strategy with a commonly used combination of antacid-alginate followed by H2-antagonist."5.08The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected]. ( Evans, WM; Mason, I; Millar, LJ; Sheikh, RR; Taylor, MD; Todd, PL; Turbitt, ML, 1998)
"In an open study 66 consecutive infected patients with ulcer disease or non-ulcer dyspepsia were treated with 4-day quadruple therapy after 3 days of lansoprazole pretreatment."5.08Four-day lansoprazole-quadruple therapy in the routine treatment of Helicobacter pylori infection. ( de Boer, WA; Schneeberger, PM; van Etten, RJ, 1998)
"In order to explore the optimal regimens for the eradication of Helicobacter pylori (Hp), eighty-eight patients with duodenal ulcer (DU) or non-ulcer dyspepsia and Hp infection, defined by culture and histology, received the one-week triple therapy with clarithromycin (Cla), furazolidone (Fur) plus lansoprazole (Lan) or colloidal bismuth subcitrate (CBS)."5.08[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. ( Liu, W; Lü, B; Xiao, S, 1996)
"Patients (n = 1262) with a clinical diagnosis of functional dyspepsia (persistent or recurrent epigastric pain or discomfort for at least 1 month and a normal upper gastrointestinal endoscopy) were randomized to receive omeprazole 20 mg, 10 mg or identical placebo, for 4 weeks."5.08Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies). ( Duckworth, M; Kordecki, H; Meineche-Schmidt, V; Pap, A; Paré, P; Räisänen, P; Schmid, V; Talley, NJ, 1998)
"We performed a randomized, placebo-controlled trial comparing the efficacy of treatment for two weeks with 20 mg of omeprazole orally twice daily, 500 mg of amoxicillin three times daily (with 500 mg of tetracycline three times daily substituted for amoxicillin in patients allergic to penicillin), and 400 mg of metronidazole three times daily (160 patients) with that of omeprazole alone (158 patients) for resolving symptoms of dyspepsia in patients with H."5.08Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia. ( Dickson, A; El-Nujumi, A; El-Omar, E; Hilditch, T; Kelman, A; Knill-Jones, R; McColl, K; Murray, L; Penny, C; Wirz, A, 1998)
"Thirty-five consecutive patients (median age: 50 years, 17 men and 18 women) suffering from Helicobacter pylori associated peptic ulcer disease (duodenal ulcer: n = 15, gastric ulcer: n = 13) or severe functional dyspepsia (n = 7) were enrolled in a two-center clinical trial and treated with omeprazole 20 mg bid preprandially and roxithromycin 300 mg bid postprandially over two weeks."5.07[Omeprazole modified antibiotic therapy of Helicobacter pylori infection: can clarithromycin be replaced by roxithromycin?]. ( Adamek, RJ; Börsch, G; Labenz, J; Opferkuch, W; Rühl, GH; Wegener, M, 1994)
"In a randomized, placebo-controlled, double-blind, crossover comparison, 12 patients with congestive heart failure (New York Heart Association class II) and dyspeptic complaints were treated orally for 1 week each with placebo, 40 mg omeprazole daily, and 40 mg famotidine daily."5.07Cardiovascular effects of omeprazole and famotidine. ( Halabi, A; Kirch, W, 1992)
"In an open study, 62 patients with Helicobacter pylori-associated ulcer disease or functional dyspepsia were treated for two weeks with 2 x 20 mg omeprazole preprandially and 4 x 500 mg amoxicillin suspension one hour before meals and at night."5.07Two weeks treatment with amoxicillin/omeprazole for eradication of Helicobacter pylori. ( Börsch, G; Gyenes, E; Labenz, J; Rühl, GH, 1992)
" Studies indicate that the omeprazole test is the most sensitive and cost effective test for diagnosing gastro-oesophageal reflux disease (GORD) in patients with extra-oesophageal or more "classic" symptoms suggestive of GORD."4.81Use of antisecretory agents as a trial of therapy. ( Fennerty, MB, 2002)
" In triple therapy, two studies used the same regimen in nonulcer dyspepsia patients: lansoprazole 30 mg/day for 2 weeks, amoxicillin 2 g/day for 2 weeks, and tinidazole 1 g/day for 2 weeks."4.78Effect of lansoprazole on Helicobacter pylori. ( Lamouliatte, H, 1993)
"The results of placebo-controlled clinical trials of the treatment of non-ulcer dyspepsia with antacids, H2-receptor blockers, pirenzepine, sucralfate and colloidal bismuth subcitrate are reviewed."4.78[Drug therapy of non-ulcer dyspepsia]. ( Bytzer, P, 1991)
" Those who tested positive for giardiasis (Group 1) were assigned to receive Tinidazole 2."3.79Giardia intestinalis in patients with nonulcer dyspepsia. ( Abulhasan, M; Albadry, A; Eida, M; Elshazly, TA, 2013)
"Patients who had heartburn twice a week or more were treated with 20 mg omeprazole (OPZ) once daily for 8 wk as an initial therapy (study 1)."3.77Proton pump inhibitor step-down therapy for GERD: a multi-center study in Japan. ( Fujiwara, A; Ishioka, H; Kawahara, Y; Nasu, J; Okada, H; Takenaka, R; Tsuzuki, T; Yamamoto, K; Yoshinaga, F, 2011)
"Although no strategy was the indisputable cost effective option, CanDys omeprazole may be the strategy of choiceover a clinically relevant range of WTP assumptions in the initial management of Canadian patients with uninvestigated dyspepsia."3.76A one-year economic evaluation of six alternative strategies in the management of uninvestigated upper gastrointestinal symptoms in Canadian primary care. ( Armstrong, D; Barkun, AN; Chakraborty, B; Chiba, N; Crott, R; Escobedo, S; Fallone, CA; Kalra, H; Kennedy, WA; Lachaine, J; Levinton, C; Nevin, K; Sinclair, P; Smyth, S; Thomson, A; Veldhuyzen van Zanten, S; White, R, 2010)
" Adverse events that occurred significantly more often in the first month of treatment with esomeprazole compared with months 2-6 included diarrhoea, nausea/vomiting, abdominal pain, dyspepsia, headache/migraine, intolerance, malaise/lassitude, pruritus, unspecified adverse effects and abnormal sensation."3.74Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England. ( Davies, M; Shakir, SA; Wilton, LV, 2008)
"This pragmatic, primary care study by Meineche-Schmidt in patients with presumed acid-related uninvestigated dyspepsia showed that a standard dose of omeprazole 20 mg daily was significantly more effective than a placebo in treating their self-worded main dyspepsia complaint."3.72Treat the patients' main dyspepsia complaint, not the ROME criteria. ( Chiba, N, 2004)
" pylori strain (34 duodenal ulcer and 37 nonulcer dyspepsia) received omeprazole 40 mg o."3.70Weekend therapy for the treatment of Helicobacter pylori infection. ( Agosti, R; Bocus, P; Caletti, G; Grigioni, WF; Mazzoni, C; Orcioni, GF; Paparo, GF; Poli, L; Sottili, S; Togliani, T; Tucci, A, 1998)
" A further evaluation was undertaken in patients with symptoms suggestive of GERD and in patients with non-ulcer dyspepsia, to identify factors that might predict symptom relief during treatment with omeprazole."3.70The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease. ( Bolling-Sternevald, E; Carlsson, R; Dent, J; Johnsson, F; Junghard, O; Lauritsen, K; Lundell, L; Riley, S, 1998)
" Sixty-six patients (with nonulcer dyspepsia, inactive ulcer, or active ulcer) were given lansoprazole (30 mg, h."3.69Endoscopic topical therapy for the treatment of Helicobacter pylori infection. ( Ishino, Y; Kihira, K; Kimura, K; Saifuku, K; Satoh, K; Takimoto, T; Taniguchi, Y; Yamamoto, H; Yoshida, Y, 1996)
"Randomized patients with available aspirin dosing information in COGENT (N = 3,752) were divided into "low-dose" (≤ 100 mg) and "high-dose" (>100 mg) aspirin groups."2.82Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M, 2016)
"Dyspepsia is a common symptom with a broad differential diagnosis and complex pathophysiology which annually affect about 25% of the general population."2.82Helicobacter pylori eradication effect on patients with functional dyspepsia symptoms. ( Hemati, K; Jodaki, A; Peyman, H; Sahraie, A; Yasemi, M; Yasemi, MR, 2016)
"In case of symptom recurrence, an endoscopy was performed."2.75Discontinuation of long-term proton pump inhibitor therapy in primary care patients: a randomized placebo-controlled trial in patients with symptom relapse. ( Bytzer, P; Reimer, C, 2010)
"A new questionnaire for assessing gastroesophageal reflux disease (GERD), the Frequency Scale for Symptoms of GERD, covers the 12 most common symptoms of GERD patients."2.73Proton pump inhibitors improve acid-related dyspepsia in gastroesophageal reflux disease patients. ( Horikoshi, T; Kawamura, O; Kuribayashi, S; Kusano, M; Maeda, M; Moki, F; Mori, M; Nagoshi, A; Shimoyama, Y; Sugimoto, S; Toki, M; Zai, H, 2007)
" Patients were randomized double-blindly to taper down or continue a constant dosage of omeprazole for three weeks."2.72Discontinuation of proton pump inhibitors in patients on long-term therapy: a double-blind, placebo-controlled trial. ( Abrahamsson, H; Agerforz, P; Björnsson, E; Jensen, C; Kilander, A; Mattsson, N; Simrén, M, 2006)
"Levodopa was prescribed for groups 1 and 3."2.72Does delayed gastric emptying shorten the H pylori eradication period? A double blind clinical trial. ( Alizadeh, M; Arj, A; Bagheri-Lankarani, K; Bahri-Najafi, R; Dehbashi, N; Emami, MH; Esmaeili, A; Fattahi, MR; Geramizadeh, B; Kaviani, MJ; Saberfiroozi, MM; Taghavi, AR, 2006)
" Both drugs induced similar false-negative UBTs on day 14 of dosing (P = 0."2.71Impact of long-term ranitidine and pantoprazole on accuracy of [13C]urea breath test. ( Biagini, R; Bilardi, C; Dulbecco, P; Gambaro, C; Iiritano, E; Mansi, C; Mele, MR; Savarino, V; Tessieri, L; Usai, P; Vigneri, S; Zentilin, P, 2003)
"Rabeprazole is a new proton pump inhibitor, which has been reported to induce a faster acid suppression than other drugs of the same category."2.71Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study. ( Bilardi, C; Dulbecco, P; Gambaro, C; Iiritano, E; Mansia, C; Savarino, V; Usai, P; Vigneri, S; Zentilin, P, 2003)
"Peptic ulcer was found in 6."2.71Does the 'test-and-treat' strategy work in primary health care for management of uninvestigated dyspepsia? A prospective two-year follow-up study of 1552 patients. ( Färkkilä, M; Sarna, S; Sipponen, P; Valtonen, V, 2004)
"A urea breath test was performed 1-2 months after eradication."2.71Eradication rate of Helicobacter pylori in dyspeptic patients. ( Amini, M; Khedmat, H; Yari, F, 2005)
"Treatment with omeprazole provides superior symptom relief compared to ranitidine, cisapride, and placebo in the treatment of H."2.71A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study. ( Armstrong, D; Barkun, A; Chiba, N; Escobedo, S; Lee, J; Sinclair, P; Smyth, S; Thomson, A; Veldhuyzen van Zanten, SJ, 2005)
"Helicobacter pylori gastritis is usually a lifelong disease which can cause different topographical inflammatory reactions and induce divergent effects on acid secretion in humans."2.70Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia. ( Färkkilä, M; Koskenpato, J; Sipponen, P, 2002)
"A urea breath test was performed 1 month after the end of therapy; patients and investigators were blind to the results."2.70Helicobacter pylori eradication does not worsen quality of life related to reflux symptoms: a prospective trial. ( Dhir, V; Laine, L, 2002)
"Symptoms of gastro-oesophageal reflux are common, and currently available methods for diagnosing reflux disease are expensive and uncomfortable for the patient."2.69One-week omeprazole treatment in the diagnosis of gastro-oesophageal reflux disease. ( Bengtsson, L; Hernqvist, H; Johnsson, F; Solhaug, JH; Weywadt, L, 1998)
"Omeprazole was better tolerated than misoprostol."2.69Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group. ( Barkun, A; Hawkey, CJ; Karrasch, JA; Swannell, AJ; Szczepañski, L; Walker, DG; Yeomans, ND, 1998)
"Omeprazole is an effective agent for gastroduodenal prophylaxis in patients taking NSAIDs."2.69Primary gastroduodenal prophylaxis with omeprazole for non-steroidal anti-inflammatory drug users. ( Bardhan, KD; Cullen, D; Eisner, M; Hawkey, CJ; Kogut, DG; Peacock, RA; Thomson, JM, 1998)
"Pretreatment with omeprazole did not reduce the cure rate for this new quadruple therapy."2.69A new quadruple therapy for the eradication of Helicobacter pylori. Effect of pretreatment with omeprazole on the cure rate. ( Maeda, K; Nishimura, H; Oda, K; Ohkuma, K; Okabe, N; Okada, M; Oki, K; Seo, M; Shirotani, T, 1998)
"pylori functional dyspepsia is prevalent in people over 60 years old."2.69Helicobacter pylori-positive functional dyspepsia in elderly patients: comparison of two treatments. ( Bentivegna, C; Branciforte, G; Brogna, A; Catalano, F; Chodash, HB; Dawson, BK; Luca, S; Michalos, A; Terranova, R, 1999)
"After eradication, 51 out of 53 treated rosacea patients became Hp negative."2.69Helicobacter pylori and its eradication in rosacea. ( Bielański, W; Karczewska, E; Konturek, SJ; Pytko-Polonczyk, J; Sliwowski, Z; Szlachcic, A, 1999)
"Functional dyspepsia is a heterogeneous condition and a uniform response to drug treatment is not likely."2.69Identifying responders to acid suppression in dyspepsia using a random starting day trial. ( Bonnevie, O; Breinstrup, H; Bytzer, P; Funch-Jensen, P; Hansen, JM; Matzen, P; Meineche-Schmidt, V; Rune, S; Schaffalitzky De Muckadell, OB, 2000)
"Omeprazole can enhance efficacy of single and double antibiotic protocols and is particularly effective when combined with clarithromycin and a nitroimidazole."2.68Omeprazole enhances efficacy of triple therapy in eradicating Helicobacter pylori. ( Andrews, P; Bae, H; Borody, TJ; Brandl, S; Fracchia, G; Shortis, NP, 1995)
"Some recent studies have reported high recurrence rates after apparent cure."2.68Long-term follow-up after cure of Helicobacter pylori infection with 4 days of quadruple therapy. ( De Boer, WA; Driessen, WM; Geuskens, LM; Lai, JY, 1996)
"Metronidazole resistance was induced in 8 out of 16 with a sensitive strain."2.68One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection. ( de Boer, WA; Ouwehand, ME; Schade, RW; Schneeberger, PM; Tytgat, GN; van Etten, RJ; van Unnik, AJ, 1997)
"Lansoprazole has superior anti-Helicobacter activity in vitro and possibly also in vivo; therefore we investigated quadruple therapy with lansoprazole."2.68Effectiveness of quadruple therapy using lansoprazole, instead of omeprazole, in curing Helicobacter pylori infection. ( de Boer, WA; Driessen, WM; Lai, JY; Schneeberger, PM; van de Wouw, BA; van Etten, RJ, 1996)
"We determined the effect of four times daily dosing with intravenous omeprazole on 24-h intragastric acidity, serum gastrin, and serum pepsinogen A and C in 10 fasting subjects (median age, 23."2.67Repeated intravenous bolus injections of omeprazole: effects on 24-hour intragastric pH, serum gastrin, and serum pepsinogen A and C. ( Baak, LC; Biemond, I; Jansen, JB; Lamers, CB, 1991)
"A diagnosis of toxic epidermal necrolysis (TEN) was made."2.45Toxic epidermal necrolysis and neutropaenia: complications of omeprazole. ( Burke, A; Burns, A; Handfield-Jones, S; Palmer, M; Sinha, A; Thakor, AS, 2009)
"Lansoprazole is an inhibitor of gastric acid secretion and also exhibits antibacterial activity against Helicobacter pylori in vitro."2.41Lansoprazole: an update of its place in the management of acid-related disorders. ( Jarvis, B; Matheson, AJ, 2001)
"Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells."2.41An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole. ( Bown, RL, 2002)
"Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia."2.41The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies. ( Lauritsen, K; Talley, NJ, 2002)
"Alopecia areata is a disease of the hair follicles, with strong evidence supporting autoimmune etiology."1.37Cure of alopecia areata after eradication of Helicobacter pylori: a new association? ( Campuzano-Maya, G, 2011)
" However, as with all drugs, PPIs should be dosed appropriately, and should be reserved for patients with conditions for which there is clear evidence of benefit from therapy."1.36Editorial: just how "difficult" is it to withdraw PPI treatment? ( Howden, CW; Kahrilas, PJ, 2010)
"Gastro-oesophageal reflux disease is one of the most common diseases in primary care and has a significant negative impact on patients' quality of life."1.33Validation of the Reflux Disease Questionnaire for a German population. ( Kulig, M; Leodolter, A; Malfertheiner, P; Nocon, M; Willich, SN, 2005)
"Acute interstitial nephritis is an uncommon but important cause of acute renal failure."1.33Rabeprazole-induced acute interstitial nephritis. ( Coleman, PL; Geevasinga, N; Roger, SD, 2005)
"pylori in children with type 1 diabetes mellitus improves their metabolic control."1.32Helicobacter pylori eradication rate and glycemic control in young patients with type 1 diabetes. ( Cammarota, G; Candelli, M; Crea, F; Gasbarrini, A; Gasbarrini, G; Marietti, G; Nista, EC; Petrucci, S; Pignataro, G; Rigante, D; Schiavino, A, 2004)
"Metronidazole resistance was significantly more common in women (P < 0."1.32Helicobacter pylori: antibiotic resistance and eradication rates in Suffolk, UK, 1991-2001. ( Baldwin, L; Bell, GD; Cameron, EAB; Jones, P; Powell, KU; Williams, SGJ, 2004)
"Presence of a gastroduodenal ulcer, age, gender and smoking habit did not differ significantly between the eradicated and noneradicated groups."1.31Failure of Helicobacter pylori eradication: is poor compliance the main cause? ( Baumann, R; Buri, P; Cunningham, M; Dederding, JP; Gallaz, L; Girard, L; Godin, N; Merki, H; Metry, JM; Sitavanc, R; Wermeille, J; Zelger, G, 2002)
"To evaluate management of dyspepsia, gastroduodenal ulcer and Helicobacter pylori infection in the setting of family practice."1.31[Management of dyspepsia, gastroduodenal ulcer and Helicobacter pylori infection in primary care]. ( Azagra, R; Calvet, X; Cubells, MJ; Gené, E; López, T, 2002)
"When omeprazole was re-started she developed fever and acute renal failure, which again settled quickly on discontinuation of omeprazole."1.30Pyrexia, anaemia and acute renal failure secondary to omeprazole. ( Arnold, IR; Ferner, RE; Landray, MJ; Ringrose, T, 1998)
"[14C]Urea breath tests were performed in 20 H."1.30Current or recent proton pump inhibitor therapy markedly impairs the accuracy of the [14C]urea breath test. ( El-Nujumi, A; Hilditch, TE; McColl, KE; Williams, C, 1998)
"In patients with systemic sclerosis peristaltic abnormalities may delay gastric emptying, giving rise to bacterial overgrowth, including possibly Helicobacter pylori (HP)."1.29Helicobacter pylori in patients with systemic sclerosis: detection with the 13C-urea breath test and eradication. ( Goerz, G; Humfeld, S; Reinauer, H; Reinauer, S; Ruzicka, T; Susanto, F, 1994)

Research

Studies (302)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's104 (34.44)18.2507
2000's169 (55.96)29.6817
2010's25 (8.28)24.3611
2020's4 (1.32)2.80

Authors

AuthorsStudies
Yongwatana, K1
Harinwan, K1
Chirapongsathorn, S1
Opuchar, K1
Sanpajit, T1
Piyanirun, W1
Puttapitakpong, C1
Corazziari, ES1
Gasbarrini, A5
D'Alba, L1
D'Ovidio, V1
Riggio, O1
Passaretti, S1
Annibale, B1
Cicala, M1
Repici, A1
Bassotti, G1
Ciacci, C1
Di Sabatino, A1
Neri, M2
Bragazzi, MC1
Ribichini, E1
Radocchia, G1
Iovino, P1
Marazzato, M1
Schippa, S1
Badiali, D1
Kongkam, P1
Khongkha, W1
Lopimpisuth, C1
Chumsri, C1
Kosarussawadee, P1
Phutrakool, P1
Khamsai, S1
Sawanyawisuth, K1
Sura, T1
Phisalprapa, P1
Buamahakul, T1
Siwamogsatham, S1
Angsusing, J1
Poonniam, P1
Wanaratna, K1
Teerachaisakul, M1
Pongpirul, K1
Valencia, ME1
Montejano, R1
Moreno, V2
Martín Carbonero, L1
Bernardino, JI1
Serrano, L1
Sharifi, R1
Nouri, M1
Eidi, A1
Noormohammadi, Z1
Dolatkhah, H1
Shirmohammadi, M1
Zullo, A5
Scaccianoce, G1
De Francesco, V6
Ruggiero, V1
D'Ambrosio, P1
Castorani, L1
Bonfrate, L1
Vannella, L1
Hassan, C3
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Branciforte, G1
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Dawson, BK1
Chodash, HB1
Hamlet, A1
Stage, L1
Lönroth, H1
Cahlin, C1
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Pettersson, A1
Moshkowitz, M1
Brill, S1
Konikoff, FM1
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Schubert, ML1
Grimm, KJ1
Farup, PG1
Hovde, O1
Torp, R1
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Wahlqvist, P1
Werdmuller, BF1
van der Putten, AB1
Veenendaal, RA1
Balk, AG1
Loffeld, RJ1
Zwimpfer, J1
Ballard, ED1
Fennerty, MB2
Hammett, DC1
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Greenberg, PD1
Cello, JP1
Adamsson, I1
Nord, CE1
Lundquist, P1
Sjöstedt, S1
Edlund, C1
Samoyeau, R2
De Mascarel, A2
Megraud, F4
Mamun, M1
Caddick, S1
Siddiqi, MA1
Lugannani, C1
Strickland, C1
Blondon, H1
Aydin, A1
Ersöz, G1
Tekesin, O1
Akçiçek, E1
Tuncyürek, M1
Dott, AG1
Johnson, L1
Szlachcic, A1
Sliwowski, Z1
Karczewska, E1
Pytko-Polonczyk, J1
Hirai, S1
Nishira, T1
Kikuchi, S1
Takei, Y1
Bojarski, C1
Epple, HJ1
Kirstein, FW1
Fromm, M1
Bisson, S1
Riecken, EO1
Schulzke, JD1
Feltbower, R2
Brown, J2
Mason, S2
Mason, J2
Richards, ID1
Dowell, AC1
Wittayalertpanya, S1
Wannachai, N1
Thongnopnua, P1
Mahachai, V1
Testoni, PA1
Bagnolo, F1
Rune, S1
Bonnevie, O1
Breinstrup, H1
Funch-Jensen, P1
Matzen, P1
Shuster, J1
Lerro, P1
Perrucci, V1
Morra, I1
Lombardo, L1
Gaido, F1
Ansaldi, N1
Hsu, PI1
Lai, KH1
Tseng, HH1
Lo, GH1
Lo, CC1
Lin, CK1
Cheng, JS1
Chan, HH1
Ku, MK1
Peng, NJ1
Chien, EJ1
Chen, W1
Hsu, PN1
Fakheri, H1
Malekzadeh, R1
Merat, S1
Khatibian, M1
Fazel, A1
Alizadeh, BZ1
Massarrat, S1
Ohkusa, T1
Fujiki, K1
Takashimizu, I1
Kumagai, J1
Tanizawa, T1
Eishi, Y1
Yokoyama, T1
Watanabe, M1
Smout, AJ3
Broutet, N1
Marais, A1
Salamon, R1
Lin, Z1
Chen, JD1
Parolisi, S1
Shifflett, J1
McCallum, RW1
Chuang, CH2
Sheu, BS2
Yang, HB2
Wu, JJ2
Lin, XZ1
Della Libera, E1
Rohr, MR1
Moraes, M1
Siqueira, ES1
Ferrari, AP1
Meier, R1
Wettstein, A1
Drewe, J1
Geiser, HR1
Luzza, F1
Giglio, A1
Ciliberto, E1
Belmonte, A1
Cavaliere, C1
Saccà, N1
Frandina, C1
Trimboli, V1
Pallone, F1
Yamada, T2
Hojo, M1
Cook, KF1
Wray, NP1
Lewin van den Broek, NT1
Numans, ME1
Buskens, E1
Verheij, TJ1
de Wit, NJ1
Froehlich, F1
Gonvers, JJ1
Wietlisbach, V1
Burnand, B1
Hildebrand, P1
Schneider, C1
Saraga, E1
Beglinger, C1
Vader, JP1
Stanghellini, V1
Galmiche, JP1
Fendrick, AM1
Tankovic, J1
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Lascols, C1
Soussy, CJ1
Laurent, J1
Fléjou, JF1
Caekaert, A1
Kearney, DJ1
Matheson, AJ1
Jarvis, B1
Misawa, H1
Ohtaka, K1
Schwartz, MP1
Samsom, M1
Van Berge Henegouwen, GP1
Wang, YL1
Huang, AH1
Schilling, D1
Messerer, P1
Ott, MG1
Schauwecker, P1
Zober, A1
Riemann, JF1
Bazzoli, F1
Zagari, RM1
Pozzato, P1
Fossi, S1
Ricciardiello, L1
Nicolini, G1
De Luca, L1
Berretti, D1
Alampi, G1
Di Pietro, C1
Morelli, P1
Roda, E1
Choi, IJ1
Choi, KW1
Kim, JH1
Ahn, DS1
Yang, US1
Rew, JS1
Lee, SI1
Rhee, JC1
Chung, IS1
Chung, JM1
Hong, WS1
Georgopoulos, SD1
Ladas, SD1
Karatapanis, S1
Triantafyllou, K1
Spiliadi, C1
Mentis, A1
Artikis, V1
Raptis, SA1
Duffett, S1
Drummond, M1
Crocombe, W1
Bown, RL1
Axon, A1
Van Zanten, SJ1
Ferguson, RA1
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Girard, L1
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Cubells, MJ1
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Knippig, C1
Arand, F1
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Bayerdörffer, E1
Klein, U1
Halabi, A1
Kirch, W1
Gyenes, E1
Burridge, SM1
Spencer, G1
Bolton, G1
Purser, K1
Brooks, S1
Prosser, S1
Harrison, G1
Gant, PW1
Baak, LC1

Clinical Trials (20)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparing the Efficacy and Impact on Gastrointestinal Microbiome of Reverse Hybrid Therapy and Bismuth Quadruple Therapy in Helicobacter Pylori Eradication[NCT02547038]352 participants (Actual)Interventional2015-02-28Completed
Comparison of Two Rescue Therapies for Helicobacter Pylori Infection - A Multicenter Randomized Controlled Trial[NCT02547012]51 participants (Actual)Interventional2013-11-30Completed
Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia: A Randomized Comparison of Different Prescribing Behaviors[NCT01851863]Phase 4262 participants (Actual)Interventional2013-05-31Completed
A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease[NCT00557921]Phase 35,000 participants (Anticipated)Interventional2007-12-31Terminated (stopped due to Terminated by Sponsor)
Helicobacter Pylori Eradication Therapy in Portugal: Prospective, Randomized, Blind and Multicentre Trial on the Efficacy of Quadruple Therapies and Their Clinical Impact, and Immunological and Gut Microbiota Changes[NCT05449028]230 participants (Anticipated)Interventional2022-05-01Recruiting
Rifaximin Associated With Classic Triple Therapy (Inhibitor of Proton Pump, Amoxicillin and Clarithromycin) for the Eradication of Helicobacter Pylori Infection[NCT03124199]Phase 340 participants (Actual)Interventional2014-02-28Completed
Dyspeptic Symptoms Evolution After Eradication of Helicobacter Pylori in Patients With Different Endoscopic Findings: a Randomized Double-blind Placebo-controlled Clinical Trial With 12 Months of Follow-up[NCT00404534]Phase 3407 participants (Actual)Interventional2006-10-31Completed
The Phase 2 Study of FP-10, the Food Ingredient Derived From Milk Casein, on the Eradication Rates of Helicobacter Pylori by a Triple Therapy With Lansoprazole, Amoxicillin, and Clarithromycin[NCT00281047]Phase 2/Phase 3138 participants Interventional2006-01-31Recruiting
Study of Gastroscopy Negative Dyspepsia - Effect of Acid-reducing Treatment and Information on Various Types of Dysmotility.[NCT00437346]35 participants (Actual)Interventional2007-01-31Terminated (stopped due to The project leader left our hospital and the project were shut down.)
High Eradication Rates of Helicobacter Pylori With a New Sequential Treatment[NCT00132171]Phase 31,000 participants Interventional2001-01-31Completed
Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441]Phase 4338 participants (Actual)Interventional2010-12-31Completed
A Greek, Single Center, Randomized, Double Blind Controlled Clinical Study Comparing the 10-day Versus the 14-day Concomitant Proton Pump Inhibitor [PPI] + Amoxicillin + Metronidazole + Clarithromycin (PAMC) Therapeutic Scheme as First-line Treatment Stra[NCT02959255]Phase 4364 participants (Actual)Interventional2017-01-30Completed
Comparison of Hybrid and Bismuth Containing Quadruple Therapies for Helicobacter Pylori Eradication: a Randomized Controlled Trial[NCT02541864]330 participants (Actual)Interventional2013-07-31Completed
Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection - a Randomized Controlled Trial (REHYTRI Study)[NCT02359435]440 participants (Actual)Interventional2012-10-31Completed
Double-blind, Placebo-controlled Study of the Safety and Efficacy of Eszopiclone in the Treatment of Insomnia in Patients With Chronic Low Back Pain[NCT00365976]Phase 458 participants (Actual)Interventional2006-08-31Completed
Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia[NCT00547703]5 participants (Actual)Interventional2008-02-29Terminated (stopped due to Not enough participants - only 5 since the study started)
Study of the Effect of PROGRESSive Withdrawal Esomeprazole of on Acid-related Symptoms, PROGRESS Study A Randomized, Placebo-controlled, Double Blinded Study[NCT02476097]Phase 458 participants (Anticipated)Interventional2015-06-30Active, not recruiting
A Randomized, Blinded, Placebo-Controlled Study of the Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on Gastroduodenal Healing[NCT00778193]Phase 4125 participants (Actual)Interventional2007-10-31Completed
Personalized Treatment for Refractory H Pylori Infection[NCT02547025]126 participants (Actual)Interventional2012-08-01Completed
Evaluation of Esophageal and Gastric Acid Levels in Patients Presenting With Upper Gastrointestinal Symptoms Using a Novel PH System[NCT00579410]85 participants (Actual)Observational2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants in Which H. Pylori Was Eradicated

Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (Number of Participants With Complete Eradication of Helicobacter Pylori) (NCT02547038)
Timeframe: sixth week after the end of anti- H. pylori therapy

Interventionparticipants (Number)
Pantoprazole+Bismuth+Tetra+Metro169
(Panto+Amox+Clar+Metr)+(Panto+Amox)170

Number of Participants in Which H. Pylori Was Eradicated

Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (NCT02547012)
Timeframe: six weeks after the end of anti-H pylori therapy.

Interventionparticipants (Number)
Esomeprazole+Amox+Levo+Tetra13
Esomeprazole+Amox+Levo21

Change From Baseline in Dyspepsia Symptom Questionnaire at Week 8

The severity of patients' dyspeptic symptoms were assessed using the Leeds Dyspepsia Questionnaire (LDQ) at week 0 and 8. The LDQ contains eight items about epigastric pain, retro-sternal pain, regurgitation, nausea, vomiting, belching, early satiety and dysphagia with six grades for each item and a sum of the eight symptom scores make the LDQ score.LDQ scores of 0 - 4 were classified as very mild dyspepsia, 4 - 8 as mild dyspepsia, 9 -15 as moderate dyspepsia, and > 15 as severe or very severe dyspepsia. The change of LDQ scores was calculated by LDQ scores of 8 weeks minus baseline, with lower values represent a better outcome. (NCT01851863)
Timeframe: week 0 and 8

Interventionunits on LDQ scale (Mean)
Deanxit(Psychological and GI) + Omeprazole-3.85
Deanxit(Psychological) + Omeprazole-2.51
Deanxit(Without Explanation) + Omeprazole-2.49
Proton Pump Inhibitor-1.31

Compliance of Flupentixol-Melitracen

The patients were asked to keep a diary to record their medication intake. At each visit (weeks 1, 2, 4, 8), the patient bring back the drug bottle and the diary, then the physician recorded the number of pills remaining in the bottle. Pills remained more than 20% at any visit or seven days of consecutive abstinence were adopted as the criterion for identifying therapy noncompliance. (NCT01851863)
Timeframe: weeks 1, 2, 4, 8

Interventionparticipants (Number)
Deanxit(Psychological and GI) + Omeprazole44
Deanxit(Psychological) + Omeprazole28
Deanxit(Without Explanation) + Omeprazole31

Number of Participants With Adverse Reaction

Number of participants with adverse reactions were recorded to analyze the safety profile of treatment. (NCT01851863)
Timeframe: 8 weeks

Interventionparticipants (Number)
Deanxit(Psychological and GI) + Omeprazole6
Deanxit(Psychological) + Omeprazole9
Deanxit(Without Explanation) + Omeprazole5
Proton Pump Inhibitor2

Change From Baseline in Psychiatric Symptom on Hospital Anxiety and Depression Scale at Week 8

Each patient was surveyed using the Hospital Anxiety and Depression Scale to assess the psychiatric symptom at week 0 and 8.The HADS consists of 14 items, seven of which assess anxiety, and seven assess depression. The anxiety and depression subscales were calculated independently. The patients were asked to answer each item on a four-point (0 - 3) scale. Scores of 0 to 7 on either subscale can be regarded as within the normal range, scores of 8 to 10 are suggestive of the presence of the respective state, and scores of 11 or higher indicate the probable presence of the respective mood disorder. The change of HADS scores was calculated by HADS anxiety and depression scores of 8 weeks minus baseline, with lower values indicate better outcome. (NCT01851863)
Timeframe: week 0 and 8

,,,
Interventionunits on HADS score (Mean)
HADS anxiety scoreHADS depression score
Deanxit(Psychological and GI) + Omeprazole-4.46-4.82
Deanxit(Psychological) + Omeprazole-2.29-2.25
Deanxit(Without Explanation) + Omeprazole-2.78-2.86
Proton Pump Inhibitor-1.68-1.88

Compliance With Treatment of Patients That Completed the Study

Percentage of patients that has comply with treatment, considered as intake of more than 90% of study drugs in patients who attended the post-treatment visit. (NCT03124199)
Timeframe: 1 month

Interventionpercentage of participants (Number)
Rifaximin100

Percentage of Participants With H.Pylori Infection Eradication

Percentage of Participants with H.Pylori Infection Eradication confirmed with urea breath test at least 4 weeks after the end of treatment (NCT03124199)
Timeframe: 1 month

Interventionpercentage of participants (Number)
Rifaximin61

Tolerability of Treatment

Patients with side effects present during treatment and in the 4 weeks after end of treatment (NCT03124199)
Timeframe: 1 month

Interventionparticipants (Number)
with diarrheawith metallic tasteheadachenauseaabdominal pain
Rifaximin139551

Number of Participants in Which H. Pylori Was Eradicated

Repeated endoscopy with rapid urease test, histological examination and culture or urea breath tests are conducted to assess H. pylori status. (NCT02541864)
Timeframe: at the 6th week after the end of anti- H. pylori therapy

Interventionparticipants (Number)
Pantoprazole+Bismuth+Tetra+Metro154
Hybrid Therapy154

Number of Participants in Which H. Pylori Was Eradicated

Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (NCT02359435)
Timeframe: at the 6th week after the end of anti- H. pylori therapy

Interventionparticipants (Number)
Reverse Hybrid Therapy206
Standard Triple Therapy191

Hamilton Depression Rating Scale (HAM-D-24)

The Hamilton Depression Scale - 24 Items (HAM-D-24) measures depression severity. Items are rated on a scale from 0 (symptoms not present) to a maximum of 2 to 4 (symptom extremely severe) for a total score range of 0 to 76. The higher the score, the more severe. (NCT00365976)
Timeframe: prenaprosyn baseline, postnaprosyn Baseline, Week 1, Week 2, week 4

,
Interventionunits on a scale (Mean)
prenaprosyn Baselinepostnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone6.456.384.544.142.62
Placebo7.106.575.535.076.21

Insomnia Severity Index (ISI)

The ISI is a seven-item self-report questionnaire that provides a global measure of insomnia severity based on difficulty falling or staying asleep, satisfaction with sleep, or degree of impairment with daytime functioning. The total score ranges from 0-28: 0-7 (no clinical insomnia), 8-14 (subthreshold insomnia), 15-21 (insomnia of moderate severity), and 22-28 (severe insomnia). (NCT00365976)
Timeframe: Prenaprosyn Baseline, Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
Prenaprosyn BaselinePostnaprosyn baselineWeek 1Week 2Week 4
Eszopiclone18.8518.0011.2810.618.38
Placebo20.2616.7812.8512.7413.75

Mean Sleep Onset Latency (SOL)

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionminutes (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone38.2822.3617.5015.28
Placebo34.1127.0023.1019.91

Mean Subjective Sleep Diary Derived Total Sleep Time (TST)

Nightly total sleep time was averaged from diary entries. (NCT00365976)
Timeframe: Postnaprosyn baseline, Week 1, week 2, week 4

,
InterventionMinutes (Mean)
postnaprosyn baselineweek 1week 2Week 4
Eszopiclone316.96403.47421.97411.97
Placebo380.45375.56382.11388.96

Number of Awakenings

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionawakenings (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone2.291.311.351.33
Placebo2.081.982.132.34

Patient Global Impression of Pain Ratings

Pain ratings included a global impression of pain rating (PGI) (1-5 rating with 1 being little pain and 5 is worst pain) (NCT00365976)
Timeframe: postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone4.023.543.303.08
Placebo3.903.824.013.80

Roland Morris Low Back Pain Inventory (RMLBPI)

"The Roland-Morris Low Back Pain Disability Questionnaire (RMLBPDQ) is a 24-item instrument that assesses the extent to which activities of daily living are affected by LBP. It is composed of 24 yes-no items assessing potential disabilities.~Scores range from 0 (no disability) to 24 (severe disability)." (NCT00365976)
Timeframe: prenaprosyn baseline, postnaprosyn Baseline, Week 1, Week 2, week 4

,
Interventionunits on a scale (Mean)
prenaprosyn Baselinepostnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone12.279.979.107.636.59
Placebo11.3310.309.059.327.94

Sleep Quality Ratings

Sleep quality ratings are based on a 1-10 Likert scale. Low scores represent poorer sleep quality and higher scores represent better quality sleep (NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionunits on a scale (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone4.525.996.186.38
Placebo4.444.905.335.29

Visual Analog Scale Pain Ratings (VAS)

Scores are measured on a 100 mm Visual Analog Scale (VAS). The VAS scale ranges from 0 to 100 mm with the lower score indicating less pain and the higher score indicating greater pain (NCT00365976)
Timeframe: Postnaprosyn baseline, Week 1, Week 2, Week 4

,
Interventionunits on a scale (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone48.5140.7234.7031.69
Placebo53.7951.9951.2551.60

Wake Time After Sleep Onset

(NCT00365976)
Timeframe: Postnaprosyn Baseline, Week 1, Week 2 week 4

,
Interventionminutes (Mean)
Postnaprosyn BaselineWeek 1Week 2Week 4
Eszopiclone91.5149.3437.0736.74
Placebo81.4376.7181.3276.18

Question on Whether Patient Has Had Adequate Relief of Abdominal Pain or Discomfort Reported by a Simple Yes or no Answer.

Patient would answer yes or no to a simple question asking whether they had adequate relief of abdominal pain or discomfort. This was measured at weeks 2,4 and 8 of the study but only week 8 was reported. What is being reported is the number of participants who answered yes. (NCT00547703)
Timeframe: 8 weeks

Interventionparticipants (Number)
Nortriptyline2
Placebo1

Reviews

27 reviews available for omeprazole and Indigestion

ArticleYear
[Proton pump inhibitors, a family of drugs in continuous expansion].
    Minerva gastroenterologica e dietologica, 2000, Volume: 46, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Barrett E

2000
Toxic epidermal necrolysis and neutropaenia: complications of omeprazole.
    The Australasian journal of dermatology, 2009, Volume: 50, Issue:3

    Topics: Acute Kidney Injury; Adult; Biopsy, Needle; Combined Modality Therapy; Diabetes Mellitus, Type 1; Di

2009
What's new: proton pump inhibitors and pediatrics.
    Pediatrics in review, 2003, Volume: 24, Issue:1

    Topics: Child; Dyspepsia; Gastroesophageal Reflux; Helicobacter Infections; Helicobacter pylori; Humans; Ome

2003
[The treatment of Helicobacter pylori infection in upper gastrointestinal disorders].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2003, Volume: 100, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Clinical Trials as Topic; Dyspepsia; Gastritis; Gastrointes

2003
Epigastric pain in dyspepsia and reflux disease.
    Reviews in gastroenterological disorders, 2003, Volume: 3 Suppl 4

    Topics: Abdominal Pain; Anti-Ulcer Agents; Drug Therapy, Combination; Dyspepsia; Gastroesophageal Reflux; He

2003
The role of proton pump inhibitors in NSAID-associated gastropathy and upper gastrointestinal symptoms.
    Reviews in gastroenterological disorders, 2003, Volume: 3 Suppl 4

    Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dyspepsia; Humans; Omeprazole; Peptic Ul

2003
Cost-effectiveness of a 'score and scope' strategy for the management of dyspepsia.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Cost-Benefit Analysis; Decision Trees; Diagn

2005
Interaction or relationship between Helicobacter pylori and non-steroidal anti-inflammatory drugs in upper gastrointestinal diseases.
    World journal of gastroenterology, 2006, Jun-28, Volume: 12, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiova

2006
[Functional dyspepsia: approaches to Helicobacter pylori eradication therapy].
    Leber, Magen, Darm, 1995, Volume: 25, Issue:3

    Topics: Clarithromycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyspepsia; Gastritis

1995
Effect of lansoprazole on Helicobacter pylori.
    Clinical therapeutics, 1993, Volume: 15 Suppl B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Drug Therapy, Combination; Dyspepsia; Helicoba

1993
Triple therapy and Helicobacter pylori.
    Australian family physician, 1996, Volume: 25, Issue:1

    Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination;

1996
A risk-benefit assessment of drugs used in the eradication of Helicobacter pylori infection.
    Drug safety, 1996, Volume: 15, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Clarithromycin; Drug Therapy, Combination; Dyspepsia; H

1996
The changing role of H2-receptor antagonists in acid-related diseases.
    European journal of gastroenterology & hepatology, 1996, Volume: 8 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clinical Trials as Topic

1996
Healing of nonsteroidal anti-inflammatory drug-associated ulcers and erosions, and relief of dyspeptic symptoms: a commentary on the new data.
    The American journal of medicine, 1998, Mar-30, Volume: 104, Issue:3A

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dyspepsia; Humans; Misoprostol; Omeprazo

1998
Eradication therapies for Helicobacter pylori.
    Journal of gastroenterology, 1998, Volume: 33 Suppl 10

    Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combi

1998
[25 years of gastric acid blockers].
    Nederlands tijdschrift voor geneeskunde, 1999, Dec-11, Volume: 143, Issue:50

    Topics: Anti-Ulcer Agents; Cimetidine; Dyspepsia; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans;

1999
Review article: tackling the "dyspeptic problem".
    Alimentary pharmacology & therapeutics, 2001, Volume: 15 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dyspepsia; Helicobacter pylori; Humans;

2001
Review article: managing the dyspeptic patient--an interactive discussion.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer

2001
Lansoprazole: an update of its place in the management of acid-related disorders.
    Drugs, 2001, Volume: 61, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce

2001
An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole.
    International journal of clinical practice, 2002, Volume: 56, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Digestive System Diseases; Duodenal Ulcer; Dyspepsia; Enzym

2002
Combined analysis of the ORCHID and OCAY studies: does eradication of Helicobacter pylori lead to sustained improvement in functional dyspepsia symptoms?
    Gut, 2002, Volume: 50 Suppl 4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Double-Blind M

2002
The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.
    Gut, 2002, Volume: 50 Suppl 4

    Topics: Adult; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Humans; Male; Omeprazole; Randomiz

2002
Approaches to uninvestigated dyspepsia.
    Gut, 2002, Volume: 50 Suppl 4

    Topics: Anti-Ulcer Agents; Dyspepsia; Humans; Omeprazole; Primary Health Care

2002
Use of antisecretory agents as a trial of therapy.
    Gut, 2002, Volume: 50 Suppl 4

    Topics: Anti-Ulcer Agents; Dyspepsia; Gastroesophageal Reflux; Humans; Omeprazole

2002
[Ecabet sodium].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Amoxicillin; Animals; Anti-Ulcer Agents; Diterpe

2002
[Non-ulcer dyspepsia and H. pylori].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: Amoxicillin; Clarithromycin; Dyspepsia; Gastric Acid; Gastric Emptying; Helicobacter Infections; Hel

2002
[Drug therapy of non-ulcer dyspepsia].
    Ugeskrift for laeger, 1991, Aug-05, Volume: 153, Issue:32

    Topics: Antacids; Bismuth; Dyspepsia; Histamine H2 Antagonists; Humans; Omeprazole; Pirenzepine; Sucralfate

1991

Trials

174 trials available for omeprazole and Indigestion

ArticleYear
Curcuma longa Linn versus omeprazole in treatment of functional dyspepsia: A randomized, double-blind, placebo-controlled trial.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:2

    Topics: Curcuma; Curcumin; Double-Blind Method; Dyspepsia; Humans; Omeprazole; Pain; Quality of Life; Treatm

2022
Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial.
    The American journal of gastroenterology, 2023, 11-01, Volume: 118, Issue:11

    Topics: Abdominal Pain; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Esophagitis; Heartburn; Humans; O

2023
Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial.
    BMJ evidence-based medicine, 2023, 11-22, Volume: 28, Issue:6

    Topics: Adult; Curcumin; Dyspepsia; Female; Humans; Middle Aged; Omeprazole; Pain; Proton Pump Inhibitors

2023
Dietary PUFA Increase Apoptosis in Stomach of Patients with Dyspeptic Symptoms and Infected with H. pylori.
    Lipids, 2017, Volume: 52, Issue:6

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Apoptosis; Caspase 3; Clarithromycin; Dietary Fats,

2017
Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Dose-Response Relationship, Drug;

2013
Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Dose-Response Relationship, Drug;

2013
Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Dose-Response Relationship, Drug;

2013
Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Dose-Response Relationship, Drug;

2013
Modified sequential Helicobacter pylori eradication therapy using high dose omeprazole and amoxicillin in the initial phase in the extensive metaboliser Turkish patients for CYP2C19 polymorphism is ineffective.
    Acta gastro-enterologica Belgica, 2014, Volume: 77, Issue:1

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cytochr

2014
Helicobacter pylori eradication in renal recipient: triple or quadruple therapy?
    Acta medica Iranica, 2014, Volume: 52, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Breath Tests; Drug Therapy, Combination;

2014
Effect of clinician-patient communication on compliance with flupentixol-melitracen in functional dyspepsia patients.
    World journal of gastroenterology, 2015, Apr-21, Volume: 21, Issue:15

    Topics: Adult; Aged; Anthracenes; Attitude of Health Personnel; China; Communication; Drug Combinations; Dys

2015
The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug The

2015
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia;

2016
Helicobacter pylori eradication effect on patients with functional dyspepsia symptoms.
    Minerva gastroenterologica e dietologica, 2016, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy,

2016
The response of Asian patients with functional dyspepsia to eradication of Helicobacter pylori infection.
    European journal of gastroenterology & hepatology, 2009, Volume: 21, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Asian People; Clarithromycin; Double-Blind Method;

2009
[Clinical observation on transcutaneous electrical acupoint stimulation for treatment of functional dyspepsia].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2009, Volume: 29, Issue:6

    Topics: Acupuncture Points; Adult; Aged; Benzamides; Domperidone; Dyspepsia; Female; Gastrointestinal Agents

2009
[Effectiveness of Ultop 10 mg using at treatment of functional (nonulcer) dyspepsia syndrome].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2009, Issue:6

    Topics: Adult; Anti-Ulcer Agents; Dyspepsia; Female; Humans; Male; Middle Aged; Omeprazole; Syndrome

2009
Discontinuation of long-term proton pump inhibitor therapy in primary care patients: a randomized placebo-controlled trial in patients with symptom relapse.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:10

    Topics: Adult; Aged; Dyspepsia; Endoscopy, Gastrointestinal; Female; Heart Neoplasms; Humans; Male; Middle A

2010
Helicobacter pylori eradication in functional dyspepsia: HEROES trial.
    Archives of internal medicine, 2011, Nov-28, Volume: 171, Issue:21

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Double-Blind M

2011
Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS).
    BMC gastroenterology, 2012, May-01, Volume: 12

    Topics: Algorithms; Benzamides; Diterpenes; Dose-Response Relationship, Drug; Dyspepsia; Famotidine; Gastroe

2012
Primary prevention of diclofenac associated ulcers and dyspepsia by omeprazole or triple therapy in Helicobacter pylori positive patients: a randomised, double blind, placebo controlled, clinical trial.
    Gut, 2002, Volume: 51, Issue:3

    Topics: Adult; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Clarithromycin; Dicl

2002
Efficacy of quadruple therapy with pantoprazole, bismuth, tetracycline and metronidazole as rescue treatment for Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2002
Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:7

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Breath Tests; Chronic Disease; Drug T

2002
Double blind, randomised, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients.
    Gut, 2002, Volume: 51, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

2002
The impact of primary antibiotic resistance on the efficacy of ranitidine bismuth citrate- vs. omeprazole-based one-week triple therapies in H. pylori eradication--a randomised controlled trial.
    Wiener klinische Wochenschrift, 2002, Jun-28, Volume: 114, Issue:12

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Resistance; Drug Therapy, Combi

2002
Seven-day triple therapy with omeprazole, amoxycillin and clarithromycin for Helicobacter pylori infection in haemodialysis patients.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:11

    Topics: Age Factors; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Dr

2002
Treatment of Helicobacter pylori in functional dyspepsia resistant to conventional management: a double blind randomised trial with a six month follow up.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Double-Blind Method; Drug Therapy, Combination; Dyspeps

2003
A double blind, randomized, placebo-controlled trial of proton pump inhibitor therapy in patients with uninvestigated dyspepsia.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:12

    Topics: Administration, Oral; Double-Blind Method; Dyspepsia; Endoscopy; Enzyme Inhibitors; Female; Follow-U

2002
Efficacy of triple therapy comprising rabeprazole, amoxicillin and metronidazole for second-line Helicobacter pylori eradication in Japan, and the influence of metronidazole resistance.
    Alimentary pharmacology & therapeutics, 2003, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2003
Effect of profound acid suppression in functional dyspepsia: a double-blind, randomized, placebo-controlled trial.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:12

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Humans; Hydrogen-Ion Concent

2002
Impact of upper endoscopy on satisfaction in patients with previously uninvestigated dyspepsia.
    Gastrointestinal endoscopy, 2003, Volume: 57, Issue:3

    Topics: Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Endoscopy, Gastrointestinal; Female; Follow-Up St

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
High eradication rates of Helicobacter pylori with a new sequential treatment.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2003
Impact of long-term ranitidine and pantoprazole on accuracy of [13C]urea breath test.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzimidazoles; Breath Tests; Dose-Response Relations

2003
Clinical and pathological implications of IgG antibody responses to Helicobacter pylori and its virulence factors in non-ulcer dyspepsia.
    Alimentary pharmacology & therapeutics, 2003, Apr-01, Volume: 17, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Agents; Antibodies, Bacterial; Double-Blind

2003
Empirical prescribing for dyspepsia: randomised controlled trial of test and treat versus omeprazole treatment.
    BMJ (Clinical research ed.), 2003, May-24, Volume: 326, Issue:7399

    Topics: Adult; Anti-Ulcer Agents; Dyspepsia; Endoscopy, Gastrointestinal; Female; Helicobacter Infections; H

2003
Is it possible to predict treatment response to a proton pump inhibitor in functional dyspepsia?
    Alimentary pharmacology & therapeutics, 2003, Jul-01, Volume: 18, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Health Status; Heartburn; He

2003
The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis.
    Alimentary pharmacology & therapeutics, 2003, Jul-15, Volume: 18, Issue:2

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Met

2003
Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Analysis of Variance; Anti-Ulcer Agents; Benzi

2003
Salvage therapy after two or more prior Helicobacter pylori treatment failures: the super salvage regimen.
    Helicobacter, 2003, Volume: 8, Issue:4

    Topics: Adult; Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Breath Te

2003
Helicobacter pylori eradication is beneficial in the treatment of functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2003, Sep-15, Volume: 18, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

2003
Absence of symptomatic benefit of lansoprazole, clarithromycin, and amoxicillin triple therapy in eradication of Helicobacter pylori positive, functional (nonulcer) dyspepsia.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Clarithromycin; Dose-Response Relations

2003
One-day quadruple therapy compared with 7-day triple therapy for Helicobacter pylori infection.
    Archives of internal medicine, 2003, Sep-22, Volume: 163, Issue:17

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Bismuth; B

2003
Role of antibiotic sensitivity testing before first-line Helicobacter pylori eradication treatments.
    Alimentary pharmacology & therapeutics, 2003, Oct-15, Volume: 18, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Resistance, Bac

2003
Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users--a randomized trial.
    Alimentary pharmacology & therapeutics, 2003, Oct-15, Volume: 18, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An

2003
Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Ag

2003
Beta-lactamase inhibitor enhances Helicobacter pylori eradication rate.
    Journal of internal medicine, 2004, Volume: 255, Issue:1

    Topics: Amoxicillin-Potassium Clavulanate Combination; beta-Lactamase Inhibitors; beta-Lactamases; Clarithro

2004
[Efficacy of Helicobacter pylori eradication in non-ulcer dyspepsia].
    Medicina clinica, 2004, Jan-31, Volume: 122, Issue:3

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combin

2004
Sequential treatment for Helicobacter pylori does not share the risk factors of triple therapy failure.
    Alimentary pharmacology & therapeutics, 2004, Feb-15, Volume: 19, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2004
Economic evaluation of Helicobacter pylori eradication in the CADET-Hp randomized controlled trial of H. pylori-positive primary care patients with uninvestigated dyspepsia.
    Alimentary pharmacology & therapeutics, 2004, Feb-01, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Clarithrom

2004
Pretreatment antimicrobial susceptibility testing is cost saving in the eradication of Helicobacter pylori.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:4

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Cost Savings; Cost-Ben

2003
Effectiveness and pharmaceutical cost of sequential treatment for Helicobacter pylori in patients with non-ulcer dyspepsia.
    Alimentary pharmacology & therapeutics, 2004, May-01, Volume: 19, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Benz

2004
Does the 'test-and-treat' strategy work in primary health care for management of uninvestigated dyspepsia? A prospective two-year follow-up study of 1552 patients.
    Scandinavian journal of gastroenterology, 2004, Volume: 39, Issue:4

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Dyspepsia; Endoscopy, Gastrointestinal

2004
Empirical treatment followed by a test-and-treat strategy is more cost-effective in comparison with prompt endoscopy or radiography in patients with dyspeptic symptoms: a randomized trial in a primary care setting.
    Family practice, 2004, Volume: 21, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Dyspepsia; Female; Gastroscopy; Helicobacter Infections; Helicobacter pylo

2004
Lansoprazole in the treatment of functional dyspepsia: two double-blind, randomized, placebo-controlled trials.
    The American journal of medicine, 2004, Jun-01, Volume: 116, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Dose-Response Relationship, Drug;

2004
Empiric treatment with high and standard dose of omeprazole in general practice: two-week randomized placebo-controlled trial and 12-month follow-up of health-care consumption.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:6

    Topics: Adult; Aged; Delivery of Health Care; Denmark; Dose-Response Relationship, Drug; Drug Administration

2004
The prolongation of triple therapy for Helicobacter pylori does not allow reaching therapeutic outcome of sequential scheme: a prospective, randomised study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti

2004
Reproducibility of a symptom response to omeprazole therapy in functional dyspepsia evaluated by a random-starting-day trial design.
    Alimentary pharmacology & therapeutics, 2004, Aug-01, Volume: 20, Issue:3

    Topics: Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Humans; Male; Middle Aged; Omeprazole; Re

2004
Identifying response to acid suppressive therapy in functional dyspepsia using a random starting day trial--is gastro-oesophageal reflux important?
    Alimentary pharmacology & therapeutics, 2004, Aug-15, Volume: 20, Issue:4

    Topics: Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Gastric Acid; Gastroesophageal Reflux; Hu

2004
A pilot study on duodenal acid exposure and its relationship to symptoms in functional dyspepsia with prominent nausea.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:9

    Topics: Adult; Case-Control Studies; Double-Blind Method; Duodenum; Dyspepsia; Female; Follow-Up Studies; Ga

2004
Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial.
    Gastroenterology, 2004, Volume: 127, Issue:4

    Topics: Adult; Aged; Arthritis; Celecoxib; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Dyspe

2004
Classification of dyspepsia and response to treatment with proton-pump inhibitors.
    Alimentary pharmacology & therapeutics, 2004, Nov-15, Volume: 20, Issue:10

    Topics: Anti-Ulcer Agents; Dyspepsia; Humans; Omeprazole; Proton Pump Inhibitors; Treatment Outcome

2004
A prospective study of oesophageal 24-h ambulatory pH monitoring in patients with functional dyspepsia.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:2

    Topics: Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Esophagus; Female; Humans; Hydrogen-Ion Concentra

2005
Eradication rate of Helicobacter pylori in dyspeptic patients.
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:4

    Topics: Analysis of Variance; Anti-Bacterial Agents; Breath Tests; Ciprofloxacin; Drug Therapy, Combination;

2005
[Effect of the Helicobacter pylori eradication in patients with functional dyspepsia: randomised placebo-controlled trial].
    Medicina clinica, 2005, Mar-26, Volume: 124, Issue:11

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Confidence Intervals;

2005
Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study.
    Alimentary pharmacology & therapeutics, 2005, May-15, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-Blind Method; Drug Administrat

2005
Helicobacter pylori eradication does not cause reflux oesophagitis in functional dyspeptic patients: a randomized, investigator-blinded, placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2005, May-15, Volume: 21, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Clarithromycin; Drug

2005
Low-dose rabeprazole, amoxicillin and metronidazole triple therapy for the treatment of Helicobacter pylori infection in Chinese patients.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An

2005
A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:7

    Topics: Adult; Aged; Cisapride; Cost-Benefit Analysis; Drug Costs; Dyspepsia; Female; Gastrointestinal Agent

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Recent success of pantoprazole -or lansoprazole- based clarithromycin plus amoxicillin treatment in the eradication of Helicobacter pylori.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2004, Volume: 15, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2004
Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications.
    The American journal of medicine, 2005, Volume: 118, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-

2005
Clinical outcomes of eradication of Helicobacter pylori in nonulcer dyspepsia in a population with a high prevalence of infection: results of a 12-month randomized, double blind, placebo-controlled study.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents

2006
Role of Helicobacter pylori virulence factor and genotypes in non-ulcer dyspepsia.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 1

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antigens, Bacterial; Bacterial Proteins; Clar

2006
Proton pump inhibitor or testing for Helicobacter pylori as the first step for patients presenting with dyspepsia? A cluster-randomized trial.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:6

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Denmark; Drug Therapy, Combinat

2006
Discontinuation of proton pump inhibitors in patients on long-term therapy: a double-blind, placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2006, Sep-15, Volume: 24, Issue:6

    Topics: Aged; Double-Blind Method; Drug Administration Schedule; Dyspepsia; Enzyme Inhibitors; Female; Gastr

2006
Economic evaluation of empirical antisecretory therapy versus Helicobacter pylori test for management of dyspepsia: a randomized trial in primary care.
    International journal of technology assessment in health care, 2006,Summer, Volume: 22, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Cost-Benefit Analysis; Dyspepsia; Endoscopy, Gastrointestinal; Female; Hel

2006
Does delayed gastric emptying shorten the H pylori eradication period? A double blind clinical trial.
    World journal of gastroenterology, 2006, Oct-21, Volume: 12, Issue:39

    Topics: Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Dopamine Agents;

2006
Proton pump inhibitors improve acid-related dyspepsia in gastroesophageal reflux disease patients.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Dyspepsia; Female; Gastroesophageal Reflux; Hu

2007
Cost-effectiveness analysis of two management strategies for dyspepsia.
    International journal of technology assessment in health care, 2007,Summer, Volume: 23, Issue:3

    Topics: Age Factors; Cost-Benefit Analysis; Dyspepsia; Female; Gastroscopy; Humans; Male; Middle Aged; Omepr

2007
Clinical trial: knowledge of negative Helicobacter pylori status reduces subsequent dyspepsia-related resource use.
    Alimentary pharmacology & therapeutics, 2007, Nov-01, Volume: 26, Issue:9

    Topics: Adult; Alkylating Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Cost-Benefit Ana

2007
Primary prevention of adverse gastroduodenal effects from short-term use of non-steroidal anti-inflammatory drugs by omeprazole 20 mg in healthy subjects: a randomized, double-blind, placebo-controlled study.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Duodenal Ulcer; Duodenoscopy; Dy

2008
Effect of a community screening for Helicobacter pylori: a 5-Yr follow-up study.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:5

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Community Health Services; Cost-Benefit Analy

2008
Symptomatic response to blocked and unblocked pentagastrin stimulation in functional dyspepsia. Comparison of responders and non-responders to omeprazole identified in a single-subject trial model.
    Digestive diseases (Basel, Switzerland), 2008, Volume: 26, Issue:3

    Topics: Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Ad

2008
Omeprazole enhances efficacy of triple therapy in eradicating Helicobacter pylori.
    Gut, 1995, Volume: 37, Issue:4

    Topics: Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Dyspepsia; Famotidine; F

1995
[Comparison of 2 treatment schemes to eradicate Helicobacter pylori].
    Revista medica de Chile, 1995, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Bismuth; Duodenal Ulcer; Dyspepsia; Endosco

1995
[Short-term triple therapy with pantoprazole, clarithromycin and metronidazole in eradication of Helicobacter pylori].
    Leber, Magen, Darm, 1995, Volume: 25, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

1995
Distinct profiles of gastritis in dyspepsia subgroups. Their different clinical responses to gastritis healing after Helicobacter pylori eradication.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:10

    Topics: Adult; Age Factors; Amoxicillin; Chronic Disease; Drug Therapy, Combination; Dyspepsia; Female; Gast

1994
One-week low-dose triple therapy for the eradication of Helicobacter pylori infection.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combinat

1995
Omeprazole plus amoxicillin for cure of Helicobacter pylori infection. Factors influencing the treatment success.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:12

    Topics: Adult; Aged; Amoxicillin; Analysis of Variance; Clinical Trials as Topic; Drug Therapy, Combination;

1994
Clinical evaluation of the effect of omeprazole, cimetidine, famotidine and ranitidine on histamine induced cutaneous wheal and flare response.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7

    Topics: Adult; Cimetidine; Drug Hypersensitivity; Dyspepsia; Famotidine; Female; Histamine; Histamine H2 Ant

1993
[Omeprazole modified antibiotic therapy of Helicobacter pylori infection: can clarithromycin be replaced by roxithromycin?].
    Leber, Magen, Darm, 1994, Volume: 24, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Clarithromycin; Drug Therapy, Combination; Dyspepsia; Female; Helico

1994
Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients.
    European journal of gastroenterology & hepatology, 1995, Volume: 7 Suppl 1

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Clarithromycin; Drug Therapy, Combina

1995
Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:2

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Azithromycin; Duodenal Ulcer; Dy

1996
A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Drug Therapy, C

1996
Low-dose omeprazole plus clarithromycin and either tinidazole or amoxycillin for Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:3

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Resistance,

1996
Only four days of quadruple therapy can effectively cure Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Th

1995
Long-term follow-up after cure of Helicobacter pylori infection with 4 days of quadruple therapy.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Dyspepsia; Heli

1996
Prevention of peptic ulcer and dyspeptic symptoms with omeprazole in patients receiving continuous non-steroidal anti-inflammatory drug therapy. A Nordic multicentre study.
    Scandinavian journal of gastroenterology, 1996, Volume: 31, Issue:8

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Double-Blind Method; Dyspep

1996
One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti

1997
Lansoprazole 30 mg daily versus ranitidine 150 mg b.d. in the treatment of acid-related dyspepsia in general practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective

1997
Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Bacterial Agents; Anti-Ulcer Agents; B

1997
Omeprazole plus clarithromycin and either tinidazole or tetracycline for Helicobacter pylori infection: a randomized prospective study.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Com

1997
Pantoprazole versus omeprazole in one-week low-dose triple therapy for curve of H. pylori infection.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; C

1997
Effectiveness of quadruple therapy using lansoprazole, instead of omeprazole, in curing Helicobacter pylori infection.
    Helicobacter, 1996, Volume: 1, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Antacids; Anti-Ulcer Agents; Bacterial Protein

1996
[Endocrine and exocrine gastric mucosal secretion in the course of H. pylori eradication in patients with non-ulcer dyspepsia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1997, Volume: 50 Suppl 1 Pt 2

    Topics: Amoxicillin; Bismuth; Dyspepsia; Epidermal Growth Factor; Gastric Juice; Gastric Mucosa; Gastrins; H

1997
One-week omeprazole treatment in the diagnosis of gastro-oesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:1

    Topics: Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Esophagoscopy; Female; Gastroesophageal Reflux; H

1998
Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group.
    The New England journal of medicine, 1998, Mar-12, Volume: 338, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Double-B

1998
Lansoprazole, amoxicillin, and clarithromycin triple therapy in vagotomized patients with dyspeptic complaints. A randomized, double-blind, placebo-controlled, clinical study without pretreatment diagnostic upper endoscopy.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected].
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Alginates; Anti-Ulcer Agents; Biocompati

1998
Four-day lansoprazole-quadruple therapy in the routine treatment of Helicobacter pylori infection.
    The Netherlands journal of medicine, 1998, Volume: 52, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Drug Administration Sch

1998
[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithrom

1996
Does endoscopy have a positive impact on quality of life in dyspepsia?
    Gastrointestinal endoscopy, 1998, Volume: 47, Issue:6

    Topics: Abdominal Pain; Activities of Daily Living; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer A

1998
Effects of Helicobacter pylori eradication on gastric function indices in functional dyspepsia. A prospective controlled study.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Dyspepsi

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
One-week triple therapy using omeprazole, amoxycillin and clarithromycin for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia: influence of dosage of omeprazole and clarithromycin.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dose-Response Relationship, D

1998
Primary gastroduodenal prophylaxis with omeprazole for non-steroidal anti-inflammatory drug users.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen

1998
First line treatment with omeprazole provides an effective and superior alternative strategy in the management of dyspepsia compared to antacid/alginate liquid: a multicentre study in general practice.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alginates; Antacids; Anti-Ulcer Agents; Dyspepsia; Family Practice;

1998
Cure of H. pylori infection using a 7-day triple therapy combining pantoprazole with two antibiotics.
    Helicobacter, 1998, Volume: 3, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

1998
Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention.
    Lancet (London, England), 1998, Sep-26, Volume: 352, Issue:9133

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Cl

1998
A new quadruple therapy for the eradication of Helicobacter pylori. Effect of pretreatment with omeprazole on the cure rate.
    Journal of gastroenterology, 1998, Volume: 33, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Dyspe

1998
Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies).
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:11

    Topics: Adenosine Triphosphatases; Adult; Anti-Ulcer Agents; Chi-Square Distribution; Confidence Intervals;

1998
Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia.
    The New England journal of medicine, 1998, Dec-24, Volume: 339, Issue:26

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combin

1998
Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group.
    The New England journal of medicine, 1998, Dec-24, Volume: 339, Issue:26

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Doub

1998
Randomized controlled trial of omeprazole or endoscopy in patients with persistent dyspepsia: a cost-effectiveness analysis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:12

    Topics: Adult; Cost-Benefit Analysis; Dyspepsia; Endoscopy; Female; Helicobacter Infections; Humans; Male; M

1998
Classification of dyspepsia. Identification of independent symptom components in 7270 consecutive, unselected dyspepsia patients from general practice.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:12

    Topics: Adult; Clinical Trials as Topic; Dyspepsia; Female; Gastrointestinal Agents; Humans; Male; Middle Ag

1998
Validation of seven graded diary cards for severity of dyspeptic symptoms in patients with non ulcer dyspepsia.
    The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1998, Issue:583

    Topics: Analysis of Variance; Diet Records; Double-Blind Method; Dyspepsia; Enzyme Inhibitors; Female; Human

1998
Eradication of Helicobacter pylori in functional dyspepsia: randomised double blind placebo controlled trial with 12 months' follow up. The Optimal Regimen Cures Helicobacter Induced Dyspepsia (ORCHID) Study Group.
    BMJ (Clinical research ed.), 1999, Mar-27, Volume: 318, Issue:7187

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; D

1999
Furazolidone-containing short-term triple therapies are effective in the treatment of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local;

1999
Low-dose lansoprazole provides greater relief of heartburn and epigastric pain than low-dose omeprazole in patients with acid-related dyspepsia.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Double-Blind Me

1999
Efficacy of 1 week omeprazole or lansoprazole-amoxycillin-clarithromycin therapy for Helicobacter pylori infection in the Japanese population.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

1999
[Eradication of Helicobacter pylori does not significantly improve dyspepsia].
    Presse medicale (Paris, France : 1983), 1999, Mar-27, Volume: 28, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Dyspepsia; Gastric Mucosa; Helicobacter pylori; Humans; Mu

1999
Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:5

    Topics: Adult; Aged; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Dyspeps

1999
Helicobacter pylori-positive functional dyspepsia in elderly patients: comparison of two treatments.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:5

    Topics: Aged; Aged, 80 and over; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; D

1999
A novel tablet-based 13C urea breath test for Helicobacter pylori with enhanced performance during acid suppression therapy.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:4

    Topics: Anti-Ulcer Agents; Breath Tests; Carbon Isotopes; Dyspepsia; Female; Helicobacter Infections; Helico

1999
The efficacy of omeprazole-based short-term triple therapy in Helicobacter pylori-positive older patients with dyspepsia.
    Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Chi-Square Distribution; Clarithr

1999
H. pylori and nonulcer dyspepsia: not guilty as charged.
    Gastroenterology, 1999, Volume: 117, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Dyspepsi

1999
Patients with functional dyspepsia responding to omeprazole have a characteristic gastro-oesophageal reflux pattern.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:6

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Gastroesophageal Reflux; Hel

1999
Impact of functional dyspepsia on quality of life and health care consumption after cessation of antisecretory treatment. A multicentre 3-month follow-up study.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:6

    Topics: Absenteeism; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Animals; Anti-Ulcer Agents

1999
Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia.
    The New England journal of medicine, 1999, Oct-07, Volume: 341, Issue:15

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Cla

1999
Functional (non-ulcer) dyspepsia and Helicobacter pylori infection. To treat or not to treat?
    Canadian family physician Medecin de famille canadien, 1999, Volume: 45

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combin

1999
Lack of effect of treatment for Helicobacter pylori on symptoms of nonulcer dyspepsia.
    Archives of internal medicine, 1999, Oct-25, Volume: 159, Issue:19

    Topics: Adult; Antibodies, Bacterial; Blotting, Western; Dyspepsia; Enzyme Inhibitors; Female; Helicobacter

1999
Comparative effects of omeprazole, amoxycillin plus metronidazole versus omeprazole, clarithromycin plus metronidazole on the oral, gastric and intestinal microflora in Helicobacter pylori-infected patients.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Co

1999
Double vs. single dose of pantoprazole in combination with clarithromycin and amoxycillin for 7 days, in eradication of Helicobacter pylori in patients with non-ulcer dyspepsia.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

1999
Garlic oil and Helicobacter pylori infection.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:2

    Topics: Adult; Allyl Compounds; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Disulfides; Dyspe

2000
Helicobacter pylori and its eradication in rosacea.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Dy

1999
Cure of Helicobacter pylori infection does not improve symptoms in non-ulcer dyspepsia patients-a double-blind placebo-controlled study.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:3

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Met

2000
Patients with dyspepsia benefit from eradication of Helicobacter pylori if other organic causes for dyspepsia were carefully ruled out.
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:3

    Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Bismuth; Clarithromycin; Diagnosis, Differential; Dose-

2000
Effect of population screening and treatment for Helicobacter pylori on dyspepsia and quality of life in the community: a randomised controlled trial. Leeds HELP Study Group.
    Lancet (London, England), 2000, May-13, Volume: 355, Issue:9216

    Topics: Adult; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Dyspepsia;

2000
Effect of omeprazole on gastric mucosa and serum levels of amoxicillin in patients with non-ulcer dyspepsia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2000, Volume: 83, Issue:6

    Topics: Adult; Amoxicillin; Drug Interactions; Dyspepsia; Enzyme Inhibitors; Female; Gastric Mucosa; Helicob

2000
Short course acid suppressive treatment for patients with functional dyspepsia: results depend on Helicobacter pylori status. The Frosch Study Group.
    Gut, 2000, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Aged; Algorithms; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Foll

2000
In dyspeptic patients without gastric phase III of the migrating motor complex, Helicobacter pylori eradication produces no short-term changes in interdigestive motility pattern.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Analysis of Variance; Biopsy, Needle; Breath Tests; Clarithromycin; Dru

2000
Which dyspepsia patients will benefit from omeprazole treatment? Analysis of a Danish multicenter trial.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Denmark; Dyspepsia; Female; Humans; Male; Middle Aged; O

2000
Identifying responders to acid suppression in dyspepsia using a random starting day trial.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:11

    Topics: Adult; Aged; Anti-Ulcer Agents; Drug Administration Schedule; Dyspepsia; Female; Gastroesophageal Re

2000
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

2001
Clarithromycin vs. furazolidone in quadruple therapy regimens for the treatment of Helicobacter pylori in a population with a high metronidazole resistance rate.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:3

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Clarithr

2001
cagA Status and eradication treatment outcome of anti-Helicobacter pylori triple therapies in patients with nonulcer dyspepsia.
    Journal of clinical microbiology, 2001, Volume: 39, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2001
Ranitidine bismuth citrate or omeprazole-based triple therapy for Helicobacter pylori eradication in Helicobacter pylori-infected non-ulcer dyspepsia.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:2

    Topics: Adult; Amoxicillin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Co

2001
Eradication of Helicobacter pylori infection in patients with duodenal ulcer and non-ulcer dyspepsia and analysis of one-year reinfection rates.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2001, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Duoden

2001
Fish oil (Eicosapen) is less effective than metronidazole, in combination with pantoprazole and clarithromycin, for Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Benz

2001
Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study.
    Clinical therapeutics, 2001, Volume: 23, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Bismuth; Clarit

2001
SODA (severity of dyspepsia assessment): a new effective outcome measure for dyspepsia-related health.
    Journal of clinical epidemiology, 2001, Volume: 54, Issue:8

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Female; Health Status; Humans; Male;

2001
A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2001, Volume: 51, Issue:469

    Topics: Anti-Ulcer Agents; Cimetidine; Cisapride; Clinical Protocols; Dyspepsia; Endoscopy, Gastrointestinal

2001
Helicobacter pylori eradication treatment does not benefit patients with nonulcer dyspepsia.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absenteeism; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2001
A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:11

    Topics: Administration, Oral; Adult; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Azit

2001
Helicobacter pylori eradication and standardized 3-month omeprazole therapy in functional dyspepsia.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Double-Blind Method; Drug Therapy, Combinatio

2001
Effect of inhibition of gastric acid secretion on antropyloroduodenal motor activity and duodenal acid hypersensitivity in functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chemoreceptor Cel

2001
Pretreatment gastric histology is helpful to predict the symptomatic response after H. pylori eradication in patients with nonulcer dyspepsia.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:12

    Topics: Adult; Anti-Ulcer Agents; Breath Tests; Dyspepsia; Female; Helicobacter Infections; Helicobacter pyl

2001
Low-dose lansoprazole and clarithromycin plus metronidazole vs. full-dose lansoprazole and clarithromycin plus amoxicillin for eradication of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacter

2002
Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Breath T

2002
Effectiveness of two quadruple, tetracycline- or clarithromycin-containing, second-line, Helicobacter pylori eradication therapies.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Antacids; Anti-Bacterial Agents; Bismuth; Clarithromycin; Drug Interactions

2002
The cost-effectiveness of population Helicobacter pylori screening and treatment: a Markov model using economic data from a randomized controlled trial.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Cost-Benefit Analysis; Dyspepsia; Female; Health Care

2002
Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: the Canadian adult dyspepsia empiric treatment-Helicobacter pylori positive (CADET-Hp) randomised controlled trial.
    BMJ (Clinical research ed.), 2002, Apr-27, Volume: 324, Issue:7344

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Breath Tests; Canada; Clarithromy

2002
Helicobacter pylori eradication does not worsen quality of life related to reflux symptoms: a prospective trial.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2002
[Inhibitors of proton pump in the treatment of non-ulcer functional dyspepsia of the reflux-like type].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Benzimidazoles; Dyspepsia; Enzyme Inhibi

2002
Cardiovascular effects of omeprazole and famotidine.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:9

    Topics: Aged; Cardiac Output; Double-Blind Method; Dyspepsia; Famotidine; Female; Heart Failure; Hemodynamic

1992
Two weeks treatment with amoxicillin/omeprazole for eradication of Helicobacter pylori.
    Zeitschrift fur Gastroenterologie, 1992, Volume: 30, Issue:11

    Topics: Amoxicillin; Biopsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, C

1992
Short report: omeprazole plus antibiotic combinations for the eradication of metronidazole-resistant Helicobacter pylori.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Adult; Aged; Bismuth; Circadian Rhythm; Drug Administration Schedule; Drug Resistance, Microbial; Dr

1992
Repeated intravenous bolus injections of omeprazole: effects on 24-hour intragastric pH, serum gastrin, and serum pepsinogen A and C.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:7

    Topics: Adult; Drug Administration Schedule; Dyspepsia; Female; Gastric Acidity Determination; Gastrins; Hum

1991

Other Studies

101 other studies available for omeprazole and Indigestion

ArticleYear
[Helicobacter pylori infection in the HIV + population: a comorbidity to think about].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2020, Volume: 33, Issue:1

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Ulcer Agents; Clarithromycin; Comor

2020
Giardia intestinalis in patients with nonulcer dyspepsia.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2013, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antiprotozoal Agents; Drug Therapy, Combination; Duodenum; Dyspepsia; Enzyme-Link

2013
Incidence of postoperative dyspepsia is not associated with prophylactic use of drugs.
    Sao Paulo medical journal = Revista paulista de medicina, 2014, Volume: 132, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Dyspeps

2014
Effects of Proton Pump Inhibitors on the Gastric Mucosa-Associated Microbiota in Dyspeptic Patients.
    Applied and environmental microbiology, 2016, 11-15, Volume: 82, Issue:22

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacteroidetes; Dyspepsia; Female; Firmicutes; Gastric

2016
Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia.
    Genetics and molecular research : GMR, 2016, Sep-16, Volume: 15, Issue:3

    Topics: Adult; Aged; Amoxicillin; Brazil; Clarithromycin; Cytochrome P-450 CYP2C19; Dyspepsia; Endoscopy, Ga

2016
A search for Helicobacter pyloriin localized vulvodynia.
    Gynecologic and obstetric investigation, 2008, Volume: 66, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Biopsy; Clarithromycin; Dysp

2008
I was recently diagnosed with "dyspepesia." Is this a fancy term for heartburn? Are there other ways of preventing and easing symptoms besides yoga classes to reduce stress and Prilosec for reflux?
    DukeMedicine healthnews, 2008, Volume: Suppl

    Topics: Diet; Dyspepsia; Enzyme Inhibitors; Gastroesophageal Reflux; Helicobacter pylori; Humans; Omeprazole

2008
[Comparison of Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia and peptic ulcer diseases according to proton pump inhibitors].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 52, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2008
Evidence that proton-pump inhibitor therapy induces the symptoms it is used to treat.
    Gastroenterology, 2009, Volume: 137, Issue:1

    Topics: Drug Administration Schedule; Dyspepsia; Evidence-Based Medicine; Gastric Acid; Gastric Mucosa; Gast

2009
Inappropriate use of proton pump inhibitors.
    Irish journal of medical science, 2010, Volume: 179, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Cross-Sectional Studies; Dyspepsia

2010
Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome.
    PloS one, 2010, Mar-24, Volume: 5, Issue:3

    Topics: Anti-Bacterial Agents; Case-Control Studies; Clarithromycin; Drug Resistance, Microbial; Dyspepsia;

2010
Editorial: just how "difficult" is it to withdraw PPI treatment?
    The American journal of gastroenterology, 2010, Volume: 105, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dyspepsia; Esophagitis; Gastric Acid; Gastroesophageal Refl

2010
A one-year economic evaluation of six alternative strategies in the management of uninvestigated upper gastrointestinal symptoms in Canadian primary care.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2010, Volume: 24, Issue:8

    Topics: Anti-Ulcer Agents; Canada; Cost of Illness; Cost-Benefit Analysis; Disease Management; Dyspepsia; En

2010
A case of gastric polyposis in antral area of stomach following prolonged proton-pump therapy.
    German medical science : GMS e-journal, 2010, Sep-02, Volume: 8

    Topics: Adult; Anti-Ulcer Agents; Dyspepsia; Humans; Male; Omeprazole; Polyps; Proton Pump Inhibitors; Stoma

2010
Antibiotic susceptibility patterns of Helicobacter pylori and triple therapy in a high-prevalence area.
    British journal of biomedical science, 2010, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resis

2010
It is difficult to discontinue PPI treatment in patients with GERD.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Clinical Trials as Topic; Dyspepsia; Esophagitis; Gastric A

2011
Proton pump inhibitor step-down therapy for GERD: a multi-center study in Japan.
    World journal of gastroenterology, 2011, Mar-21, Volume: 17, Issue:11

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Drug Administration Schedul

2011
Cure of alopecia areata after eradication of Helicobacter pylori: a new association?
    World journal of gastroenterology, 2011, Jul-14, Volume: 17, Issue:26

    Topics: Adult; Alopecia Areata; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Dyspepsia;

2011
[Adverse events associated with long-term use of proton pump inhibitors].
    Ugeskrift for laeger, 2012, Sep-24, Volume: 174, Issue:39

    Topics: Anti-Ulcer Agents; Bacterial Infections; Congenital Abnormalities; Dyspepsia; Fractures, Bone; Gastr

2012
Early relief of upper gastrointestinal dyspeptic symptoms: a survey of empirical therapy with pantoprazole in Canadian clinical practice.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2002, Volume: 16, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Anti-Ulcer Agents; Benzimidazoles; Canad

2002
Functional dyspepsia: bye-bye to PPIs.
    Gut, 2002, Volume: 51, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; China; Dyspepsia; Gastroesophageal R

2002
Quantification of Helicobacter pylori resistance in functional and organic dyspepsia.
    Journal of clinical pharmacy and therapeutics, 2002, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Cohort Studies; Drug

2002
Sequential eradicating therapy: a treatment that does not discriminate Helicobacter pylori strains in patients with nonulcer dyspepsia?
    The American journal of gastroenterology, 2002, Volume: 97, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti

2002
[Heartburn without esophagitis. Symptoms more important than the finding?].
    MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39

    Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul

2003
[Long-term course of reflux symptoms following Helicobacter pylori eradication].
    Deutsche medizinische Wochenschrift (1946), 2004, Mar-26, Volume: 129, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromyci

2004
Helicobacter pylori eradication rate and glycemic control in young patients with type 1 diabetes.
    Journal of pediatric gastroenterology and nutrition, 2004, Volume: 38, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Benz

2004
Helicobacter pylori: antibiotic resistance and eradication rates in Suffolk, UK, 1991-2001.
    Journal of medical microbiology, 2004, Volume: 53, Issue:Pt 6

    Topics: Adult; Age Factors; Amoxicillin; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combinati

2004
Early epigastric pain after PPI administration: exacerbation of Helicobacter pylori corpus gastritis?
    Helicobacter, 2004, Volume: 9, Issue:1

    Topics: Abdominal Pain; Anti-Ulcer Agents; Dyspepsia; Gastritis; Gastroesophageal Reflux; Helicobacter Infec

2004
Treat the patients' main dyspepsia complaint, not the ROME criteria.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:6

    Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Dyspepsia; Enzyme Inhibitors; Family

2004
Do procalcitonin and C-reactive protein levels have a place in the diagnosis and follow-up of Helicobacter pylori infections?
    Journal of medical microbiology, 2004, Volume: 53, Issue:Pt 7

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Biomarkers; Biopsy; C-Reactive Protein; Calcitonin;

2004
[Prevention of ulcer lesions under non-steroid antirheumatic agents. For each patient the appropriate stomach protection].
    MMW Fortschritte der Medizin, 2004, May-27, Volume: 146, Issue:22

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Dyspepsia; Hi

2004
[The effect of Helicobacter pylori eradication on prokinetic treatment on the quality of life in functional dyspepsia].
    Orvosi hetilap, 2004, Oct-17, Volume: 145, Issue:42

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles

2004
The use of subcutaneous omeprazole in the treatment of dyspepsia in palliative care patients.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:6

    Topics: Abdominal Pain; Aged; Anti-Ulcer Agents; Dyspepsia; Enzyme Inhibitors; Female; Humans; Injections, S

2004
Standard treatment for Helicobacter pylori infection is suboptimal in non-ulcer dyspepsia compared with duodenal ulcer in Chinese.
    Alimentary pharmacology & therapeutics, 2005, Jan-01, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Asian People; Clarithromycin; Drug Resistan

2005
Validation of the Reflux Disease Questionnaire for a German population.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Cross-Cultural Comparison; Dyspepsia; Female; Gastroesophageal Reflu

2005
Bacteriostatic and bactericidal activity of rabeprazole against Helicobacter pylori.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

2004
Rabeprazole-induced acute interstitial nephritis.
    Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Acute Kidney Injury; Anti-Ulcer Agents; Benz

2005
Helicobacter pylori status and symptom assessment two years after eradication in pediatric patients from a high prevalence area.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 40, Issue:3

    Topics: Adolescent; Age Factors; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Child;

2005
Helicobacter pylori eradication in the management of patients with idiopathic thrombocytopenic purpura.
    The American journal of medicine, 2005, Volume: 118, Issue:4

    Topics: Amoxicillin; Breath Tests; Clarithromycin; Dyspepsia; Female; Follow-Up Studies; Helicobacter Infect

2005
CagA status and Helicobacter pylori eradication among dyspeptic patients.
    Gastroenterologia y hepatologia, 2005, Volume: 28, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

2005
Improvement of gastrointestinal quality of life scores in cases of Helicobacter pylori-positive functional dyspepsia after successful eradication therapy.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Amoxicillin; Anti-Bacterial Agents; Anti-Ul

2005
Can lansoprazole, amoxicillin, and clarithromycin combination still be used as a first-line therapy for eradication of helicobacter pylori?
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2005, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adult; Amoxicillin; Anti-Bacterial Agents; A

2005
Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials.
    Alimentary pharmacology & therapeutics, 2006, Feb-15, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Dyspepsia; Female; Humans; Male; Midd

2006
Helicobacter pylori eradication in peptic dyspepsia.
    East African medical journal, 2005, Volume: 82, Issue:12

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Administration

2005
Proton pump inhibitors and acute interstitial nephritis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Kidney Injury; Adult; Age Distribution; Aged; Aged, 8

2006
Management of the dyspeptic patient: anything goes?
    The American journal of gastroenterology, 2006, Volume: 101, Issue:6

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Denmark; Drug Therapy, Combinat

2006
The management of upper gastrointestinal symptoms: is endoscopy indicated?
    The Medical journal of Australia, 2007, Feb-19, Volume: 186, Issue:4

    Topics: Age Factors; Antacids; Anti-Ulcer Agents; Dyspepsia; Endoscopy, Digestive System; Gastroesophageal R

2007
Eradication rates of helicobacter pylori infection with second-line treatment: non-ulcer dyspepsia compared to peptic ulcer disease.
    Hepato-gastroenterology, 2007, Volume: 54, Issue:76

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Dysp

2007
I was recently diagnosed with "dyspepsia". Is this just a fancy term for heartburn? Are there other ways of preventing and easing symptoms besides yoga classes to reduce stress and Prilosec for reflux?
    DukeMedicine healthnews, 2007, Volume: 13, Issue:7

    Topics: Anti-Ulcer Agents; Dyspepsia; Gastroesophageal Reflux; Humans; Meditation; Omeprazole; Stress, Physi

2007
A comparison of community pharmacists' views of over-the-counter omeprazole and simvastatin.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:12

    Topics: Anticholesteremic Agents; Attitude of Health Personnel; Community Pharmacy Services; Dyspepsia; Huma

2007
[Evidence based treatment strategy for dyspeptic symptoms].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:11

    Topics: Dyspepsia; Evidence-Based Medicine; Gastritis; Histamine H2 Antagonists; Humans; Omeprazole; Proton

2007
Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England.
    Drug safety, 2008, Volume: 31, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Cohort Studies; Diarrhea; Drug Monitoring; Dyspepsia; Engla

2008
[Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori].
    Zeitschrift fur Gastroenterologie, 1995, Volume: 33, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin

1995
Prescribing of antacids and ulcer-healing drugs in primary care in the north of England.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Aged; Antacids; Child; Child, Preschool; Drug Prescriptions; Dr

1995
Helicobacter pylori in patients with systemic sclerosis: detection with the 13C-urea breath test and eradication.
    Acta dermato-venereologica, 1994, Volume: 74, Issue:5

    Topics: Adult; Aged; Amoxicillin; Breath Tests; Carbon Isotopes; Drug Therapy, Combination; Dyspepsia; Esoph

1994
[Azithromycin-omeprazole. Treatment for the eradication of Helicobacter pylori].
    Minerva gastroenterologica e dietologica, 1994, Volume: 40, Issue:1

    Topics: Adult; Aged; Azithromycin; Drug Evaluation; Drug Therapy, Combination; Dyspepsia; Female; Helicobact

1994
Azithromycin for the cure of Helicobacter pylori infection.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:2

    Topics: Adult; Aged; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Azithromycin; Drug Therapy, Combina

1996
General practitioners' approach to dyspepsia. Survey of consultation frequencies, treatment, and investigations.
    Scandinavian journal of gastroenterology, 1996, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Age Factors; Cross-Sectional Studies; Dyspepsia; Endoscopy, Digestive System; Fem

1996
Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithrom

1996
Endoscopic topical therapy for the treatment of Helicobacter pylori infection.
    Journal of gastroenterology, 1996, Volume: 31 Suppl 9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Topical; Amoxicillin; Antacids; Anti-Ulcer

1996
[Good results with Helicobacter pylori eradication for treatment of non-ulcer dyspepsia].
    Leber, Magen, Darm, 1996, Volume: 26, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; D

1996
Evaluation of the dyspeptic patient: a cost-utility study.
    The Journal of family practice, 1997, Volume: 44, Issue:6

    Topics: Adult; Ambulatory Care; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies,

1997
Metronidazole resistance reduces efficacy of triple therapy and leads to secondary clarithromycin resistance.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:10

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Resistance, Microbial; D

1997
One-day high-dose combined therapy of Helicobacter pylori infection.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:10

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Drug Evaluation; Drug Therapy, Combination;

1997
Management in general practice of patients with persistent dyspepsia. A decision analysis.
    Journal of clinical gastroenterology, 1997, Volume: 25, Issue:4

    Topics: Decision Trees; Disease Management; Dyspepsia; Endoscopy; Gastroenterology; Humans; Omeprazole; Trea

1997
Does Helicobacter pylori infection affect gastric emptying in patients with functional dyspepsia?
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Dyspepsia; Female; Gastric Empty

1997
Weekend therapy for the treatment of Helicobacter pylori infection.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:5

    Topics: Adult; Aged; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Sc

1998
Assessment of symptomatic response as predictor of Helicobacter pylori status following eradication therapy in patients with ulcer.
    Gut, 1998, Volume: 42, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Breath T

1998
Four-day quadruple therapy as a routine treatment for Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

1997
[Is dental plaque a normal Helicobacter pylori reservoir?].
    Acta gastroenterologica Latinoamericana, 1998, Volume: 28, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Benzimidazoles; Clari

1998
Pyrexia, anaemia and acute renal failure secondary to omeprazole.
    Postgraduate medical journal, 1998, Volume: 74, Issue:873

    Topics: Acute Kidney Injury; Aged; Anemia; Anti-Inflammatory Agents; Anti-Ulcer Agents; Blood Sedimentation;

1998
The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:10

    Topics: Anti-Ulcer Agents; Dyspepsia; Endoscopy, Digestive System; Esophagitis, Peptic; Gastric Acidity Dete

1998
Current or recent proton pump inhibitor therapy markedly impairs the accuracy of the [14C]urea breath test.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:9

    Topics: Anti-Ulcer Agents; Antigens, Bacterial; Breath Tests; Dyspepsia; False Negative Reactions; False Pos

1998
Helicobacter pylori and nonulcer dyspepsia.
    The New England journal of medicine, 1998, Dec-24, Volume: 339, Issue:26

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Dyspepsia; Endoscopy, Gastroint

1998
Serum gastrin and chromogranin A during medium- and long-term acid suppressive therapy: a case-control study.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Case-Control Studies; Chromogranin A; Chromogranins; Cross-Sectional

1999
Treatment of Helicobacter pylori infection in functional dyspepsia.
    The Journal of family practice, 1999, Volume: 48, Issue:7

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Drug The

1999
Functional dyspepsia has a good prognosis irrespective of H. pylori status. Long-term follow-up of symptoms after anti H. pylori treatment.
    The Netherlands journal of medicine, 1999, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination; Dyspepsia

1999
[Symptomatic improvement of patients with nonulcer dyspepsia after Helicobacter pylori eradication].
    Praxis, 1999, Aug-15, Volume: 88, Issue:31-32

    Topics: Amoxicillin; Anti-Ulcer Agents; Breath Tests; Drug Therapy, Combination; Dyspepsia; Helicobacter Inf

1999
Is there any difference in Helicobacter pylori eradication rates in patients with active peptic ulcer, inactive peptic ulcer and functional dyspepsia?
    European journal of gastroenterology & hepatology, 1999, Volume: 11 Suppl 2

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Dy

1999
Omeprazole and excessive sweating, if unrecognised, may lead to unnecessary investigations.
    Postgraduate medical journal, 1999, Volume: 75, Issue:889

    Topics: Anti-Ulcer Agents; Dyspepsia; Humans; Hyperhidrosis; Male; Middle Aged; Omeprazole; Proton Pump Inhi

1999
Empiric eradication therapy or endoscopy in Helicobacter pylori-positive patients?
    The Journal of family practice, 1999, Volume: 48, Issue:12

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Combined Modality Therapy; Dyspepsi

1999
[Eradication of Helicobacter pylori: what is the effect on symptoms of non-ulcerous dyspepsia?].
    Presse medicale (Paris, France : 1983), 1999, Dec-11, Volume: 28, Issue:39

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dyspepsia; Female; Helicobact

1999
Rational prescribing: practice audit and drug switch in dyspepsia management.
    International journal of clinical practice, 1999, Volume: 53, Issue:8

    Topics: Cost Savings; Dyspepsia; Family Practice; Histamine H2 Antagonists; Humans; Medical Audit; Omeprazol

1999
No H pylori: less dyspepsia?
    Gut, 2000, Volume: 47, Issue:4

    Topics: Anti-Ulcer Agents; Dyspepsia; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Rese

2000
Omeprazole and nephritis.
    Nursing, 2000, Volume: 30, Issue:10

    Topics: Acute Kidney Injury; Aged; Anti-Ulcer Agents; Dyspepsia; Female; Humans; Nephritis, Interstitial; Om

2000
CagA seropositivity and the severity of Helicobacter pylori infection in dyspeptic children.
    Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:11

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Bacterial

2000
Improvement in atrophic gastritis and intestinal metaplasia in patients in whom Helicobacter pylori was eradicated.
    Annals of internal medicine, 2001, Mar-06, Volume: 134, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop

2001
Dyspepsia responsive to acid suppression therapy: reflux disease or duodenal hypersensitivity?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2000, Volume: 32 Suppl 3

    Topics: Antacids; Duodenum; Dyspepsia; Gastric Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Huma

2000
Prevalence of gastric myoelectrical abnormalities in patients with nonulcer dyspepsia and H. pylori infection: resolution after H. pylori eradication.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Dyspepsia; Electromyography;

2001
Strategy for retreatment of therapeutic failure of eradication of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2001
Noninvasive Helicobacter pylori testing for the "test-and-treat" strategy: a decision analysis to assess the effect of past infection on test choice.
    Archives of internal medicine, 2001, Sep-24, Volume: 161, Issue:17

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Antibodies, Bacterial; Antigens, Bacterial; Br

2001
Clarithromycin resistance of Helicobacter pylori has a major impact on the efficacy of the omeprazole-amoxicillin-clarithromycin therapy.
    Pathologie-biologie, 2001, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Biopsy; Clarithromycin; DNA, Bacterial; Dru

2001
Key topics in Helicobacter pylori eradication in the management of the dyspeptic patient: a panel discussion.
    European journal of gastroenterology & hepatology, 2001, Volume: 13 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Drug Resistance; Drug Therapy, Combination; Dyspepsia; Heli

2001
Helicobacter pylori eradication in functional dyspepsia: new evidence for symptomatic benefit.
    European journal of gastroenterology & hepatology, 2001, Volume: 13 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chronic Disease; Dyspepsia; Gastritis; Helicobacter Infecti

2001
The role of treatment with proton pump inhibitors and anti-Helicobacter therapy in functional dyspepsia.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Dyspepsia; Enzyme Inhibitors; Helicob

2001
Clarithromycin resistance, but not CYP2C-19 polymorphism, has a major impact on treatment success in 7-day treatment regimen for cure of H. pylori infection: a multiple logistic regression analysis.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:11

    Topics: Amoxicillin; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cytochrome P-450

2001
[Dyspepsia and Helicobacter pylori infection in employees of a large industry. Results of a prospective BASF Helicobacter pylori prevention campaign].
    Medizinische Klinik (Munich, Germany : 1983), 2002, Jan-15, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Clarithromycin; Drug Therapy, Combination; Dyspepsia; Female; Gastritis; Germany;

2002
pH-Hp: implications for dyspepsia management.
    Gut, 2002, Volume: 50 Suppl 4

    Topics: Dyspepsia; Helicobacter Infections; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Omepraz

2002
Failure of Helicobacter pylori eradication: is poor compliance the main cause?
    Gastroenterologie clinique et biologique, 2002, Volume: 26, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithrom

2002
[Management of dyspepsia, gastroduodenal ulcer and Helicobacter pylori infection in primary care].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chi-Square Distribution; Clarithromycin; Drug

2002
Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up.
    Zeitschrift fur Gastroenterologie, 2002, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breath Tests; Child; Child, Preschool; Clarithromycin; D

2002