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omeprazole and Idiopathic Pulmonary Fibrosis

omeprazole has been researched along with Idiopathic Pulmonary Fibrosis in 1 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Idiopathic Pulmonary Fibrosis: A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.

Research Excerpts

ExcerptRelevanceReference
"Forty-five participants were randomised (23 to omeprazole, 22 to placebo), with 40 (20 in each group) having cough monitoring before and after treatment."9.30Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis. ( Dutta, P; Forbes, R; Forrest, IA; Funston, W; Griffin, SM; Jones, R; Mossop, H; Pearson, J; Ryan, V; Sen, S; Simpson, AJ; Smith, JA; Ward, C, 2019)
"Forty-five participants were randomised (23 to omeprazole, 22 to placebo), with 40 (20 in each group) having cough monitoring before and after treatment."5.30Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis. ( Dutta, P; Forbes, R; Forrest, IA; Funston, W; Griffin, SM; Jones, R; Mossop, H; Pearson, J; Ryan, V; Sen, S; Simpson, AJ; Smith, JA; Ward, C, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dutta, P1
Funston, W1
Mossop, H1
Ryan, V1
Jones, R1
Forbes, R1
Sen, S1
Pearson, J1
Griffin, SM1
Smith, JA1
Ward, C1
Forrest, IA1
Simpson, AJ1

Trials

1 trial available for omeprazole and Idiopathic Pulmonary Fibrosis

ArticleYear
Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis.
    Thorax, 2019, Volume: 74, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Cough; Double-Blind Method; Feasibility Studies; Female; Forced Expi

2019