omeprazole has been researched along with Hypoxia in 5 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Evaluation of prophylactic effects of omeprazole and/or vitamin E on the formation of free oxygen radicals (FOR) and bowel histopathology in the newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC)." | 7.74 | Protective effects of vitamin E and omeprazole on the hypoxia/reoxygenation induced intestinal injury in newborn rats. ( Ariturk, E; Aydin, O; Bernay, F; Bicakci, U; Cadir, FO; Kilicoglu-Aydin, B; Rizalar, R; Tander, B, 2008) |
| "We utilized a newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC) to investigate the effects of omeprazole and/or gentamicin on the formation of free oxygen radicals (FOR) and bowel histopathology." | 7.73 | Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats. ( Aritürk, E; Aydin, BK; Aydin, O; Bernay, F; Biçakçi, U; Eren, Z; Rizalar, R; Tander, B, 2005) |
| "The effect of hypoxia on the elimination of omeprazole, a potent inhibitor of gastric acid secretion, was studied in the isolated perfused rat liver." | 7.67 | Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver. ( Jones, DB; Mihaly, GW; Morgan, DJ; Smallwood, RA; Webster, LK, 1985) |
| "Evaluation of prophylactic effects of omeprazole and/or vitamin E on the formation of free oxygen radicals (FOR) and bowel histopathology in the newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC)." | 3.74 | Protective effects of vitamin E and omeprazole on the hypoxia/reoxygenation induced intestinal injury in newborn rats. ( Ariturk, E; Aydin, O; Bernay, F; Bicakci, U; Cadir, FO; Kilicoglu-Aydin, B; Rizalar, R; Tander, B, 2008) |
| "We utilized a newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC) to investigate the effects of omeprazole and/or gentamicin on the formation of free oxygen radicals (FOR) and bowel histopathology." | 3.73 | Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats. ( Aritürk, E; Aydin, BK; Aydin, O; Bernay, F; Biçakçi, U; Eren, Z; Rizalar, R; Tander, B, 2005) |
| "The effect of hypoxia on the elimination of omeprazole, a potent inhibitor of gastric acid secretion, was studied in the isolated perfused rat liver." | 3.67 | Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver. ( Jones, DB; Mihaly, GW; Morgan, DJ; Smallwood, RA; Webster, LK, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sorokina, EA | 1 |
| Fokin, AA | 1 |
| Akhmedov, VA | 1 |
| Safechuk, VV | 1 |
| Kopeĭkin, SA | 1 |
| Trubina, TV | 1 |
| Li, XY | 1 |
| Liu, YN | 1 |
| Yuan, M | 1 |
| Li, YP | 1 |
| Yang, YZ | 1 |
| Zhu, JB | 1 |
| Biçakçi, U | 2 |
| Tander, B | 2 |
| Aritürk, E | 2 |
| Aydin, BK | 1 |
| Aydin, O | 2 |
| Rizalar, R | 2 |
| Eren, Z | 1 |
| Bernay, F | 2 |
| Cadir, FO | 1 |
| Kilicoglu-Aydin, B | 1 |
| Webster, LK | 1 |
| Jones, DB | 1 |
| Mihaly, GW | 1 |
| Morgan, DJ | 1 |
| Smallwood, RA | 1 |
5 other studies available for omeprazole and Hypoxia
| Article | Year |
|---|---|
[The role of gastric pH and tissue hypoxia in formation of gastroduodenal zone mucose changes in heartsurgical patients].
Topics: Aged; Anti-Ulcer Agents; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Gastric Mucosa | 2012 |
[Effect of high altitude hypoxia on the activity and protein expression of CYP2C9 and CYP2C19].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Altitude; Animals; Cytochrome P-450 E | 2012 |
Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Anti-Ulcer Agents; Disease Models, Animal; Enteroc | 2005 |
Protective effects of vitamin E and omeprazole on the hypoxia/reoxygenation induced intestinal injury in newborn rats.
Topics: Administration, Oral; Animals; Animals, Newborn; Anti-Ulcer Agents; Antioxidants; Disease Models, An | 2008 |
Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver.
Topics: Animals; Benzimidazoles; Hypoxia; Lactates; Lactic Acid; Liver; Male; Omeprazole; Oxidation-Reductio | 1985 |