omeprazole has been researched along with Hypoparathyroidism in 6 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Hypoparathyroidism: A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 65-year old female who had been using omeprazole for 10 years, presented with arrhythmia and paresthesia of the lower and upper limbs that had been attributed to severe hypomagnesemia, hypocalcemia, and hypoparathyroidism." | 3.81 | An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor. ( Dias-da-Silva, MR; dos Santos, LM; Guerra, RA; Lazaretti-Castro, M; Portes, Ede S; Vieira, JG, 2015) |
| " Etiologic investigations led to the discovery of Giardiasis lamblia on duodenal biopsies and a long-term treatment with proton pump inhibitors (PPI) (omeprazole followed by esomeprazole), both being recently described as causal factors of hypomagnesemic hypoparathyroidism." | 3.74 | [Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?]. ( Caron, J; Durlach, V; François, M; Lévy-Bohbot, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| dos Santos, LM | 1 |
| Guerra, RA | 1 |
| Lazaretti-Castro, M | 1 |
| Vieira, JG | 1 |
| Portes, Ede S | 1 |
| Dias-da-Silva, MR | 1 |
| François, M | 1 |
| Lévy-Bohbot, N | 1 |
| Caron, J | 1 |
| Durlach, V | 1 |
| Doornebal, J | 1 |
| Bijlsma, R | 1 |
| Brouwer, RM | 1 |
| Rodríguez Ortega, P | 1 |
| Rebollo Pérez, I | 1 |
| Laínez López, M | 1 |
| Roldán Mayorga, E | 1 |
| Hernández Lavado, R | 1 |
| Creagh Cerquera, R | 1 |
| Famularo, G | 1 |
| Minisola, G | 1 |
| Bravi, MC | 1 |
| Colucci, P | 1 |
| Gasbarrone, L | 1 |
| Epstein, M | 1 |
| McGrath, S | 1 |
| Law, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients[NCT01426165] | 5 participants (Actual) | Interventional | 2011-04-30 | Terminated (stopped due to Issues with recruitment. PI decided to terminate study) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for omeprazole and Hypoparathyroidism
| Article | Year |
|---|---|
An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor.
Topics: Aged; Arrhythmias, Cardiac; Biomarkers; Diagnosis, Differential; Down-Regulation; Electrocardiograph | 2015 |
[Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].
Topics: Deglutition Disorders; Duodenum; Esomeprazole; Female; Giardiasis; Humans; Hypocalcemia; Hypoparathy | 2008 |
[An unknown but potentially serious side effect of proton pump inhibitors: hypomagnesaemia].
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Female; Humans; Hypocalcemia; Hypokalemia; Hypoparathyro | 2009 |
Severe hypomagnesemia and hypoparathyroidism induced by omeprazole.
Topics: Humans; Hypercalciuria; Hypoparathyroidism; Male; Middle Aged; Nephrocalcinosis; Omeprazole; Proton | 2013 |
Tetany, hypomagnesemia, and proton-pump inhibitors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biomarkers; Female; Humans; Hypoparathyroidism; Magnesium; | 2012 |
Proton-pump inhibitors and hypomagnesemic hypoparathyroidism.
Topics: Aged, 80 and over; Anti-Ulcer Agents; Calcium; Female; Humans; Hypoparathyroidism; Magnesium; Male; | 2006 |