omeprazole has been researched along with Hypocalcemia in 9 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 65-year old female who had been using omeprazole for 10 years, presented with arrhythmia and paresthesia of the lower and upper limbs that had been attributed to severe hypomagnesemia, hypocalcemia, and hypoparathyroidism." | 3.81 | An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor. ( Dias-da-Silva, MR; dos Santos, LM; Guerra, RA; Lazaretti-Castro, M; Portes, Ede S; Vieira, JG, 2015) |
| " Etiologic investigations led to the discovery of Giardiasis lamblia on duodenal biopsies and a long-term treatment with proton pump inhibitors (PPI) (omeprazole followed by esomeprazole), both being recently described as causal factors of hypomagnesemic hypoparathyroidism." | 3.74 | [Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?]. ( Caron, J; Durlach, V; François, M; Lévy-Bohbot, N, 2008) |
| "Two cases of severe hypomagnesaemia in adult long-term users of the PPI omeprazole, presenting with hypocalcaemic seizures." | 3.74 | Severe hypomagnesaemia in long-term users of proton-pump inhibitors. ( Cundy, T; Dissanayake, A, 2008) |
| "Treatment with omeprazole significantly reduced serum Mg2+ and Ca2+ levels." | 1.42 | Dietary Inulin Fibers Prevent Proton-Pump Inhibitor (PPI)-Induced Hypocalcemia in Mice. ( Bindels, RJ; de Baaij, JH; Gommers, LM; Hess, MW; Hoenderop, JG, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Isse, N | 1 |
| Hashimoto, M | 1 |
| Hess, MW | 1 |
| de Baaij, JH | 1 |
| Gommers, LM | 1 |
| Hoenderop, JG | 1 |
| Bindels, RJ | 1 |
| dos Santos, LM | 1 |
| Guerra, RA | 1 |
| Lazaretti-Castro, M | 1 |
| Vieira, JG | 1 |
| Portes, Ede S | 1 |
| Dias-da-Silva, MR | 1 |
| François, M | 1 |
| Lévy-Bohbot, N | 1 |
| Caron, J | 1 |
| Durlach, V | 1 |
| Shabajee, N | 1 |
| Lamb, EJ | 1 |
| Sturgess, I | 1 |
| Sumathipala, RW | 1 |
| Doornebal, J | 1 |
| Bijlsma, R | 1 |
| Brouwer, RM | 1 |
| Subbiah, V | 1 |
| Tayek, JA | 1 |
| Cundy, T | 1 |
| Dissanayake, A | 1 |
| Aou, S | 1 |
| Ma, J | 1 |
| Shiramine, K | 1 |
| Hori, T | 1 |
9 other studies available for omeprazole and Hypocalcemia
| Article | Year |
|---|---|
Omeprazole-induced hypomagnesaemia, causing renal tubular acidosis with hypokalaemia, hypocalcaemia, hyperlactacidaemia and hyperammonaemia.
Topics: Acidosis, Renal Tubular; Aged; Humans; Hyperammonemia; Hyperlactatemia; Hypocalcemia; Hypokalemia; M | 2020 |
Dietary Inulin Fibers Prevent Proton-Pump Inhibitor (PPI)-Induced Hypocalcemia in Mice.
Topics: Animals; Calcium; Dietary Fiber; Drug Evaluation, Preclinical; Fatty Acids; Hypocalcemia; Intestinal | 2015 |
An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor.
Topics: Aged; Arrhythmias, Cardiac; Biomarkers; Diagnosis, Differential; Down-Regulation; Electrocardiograph | 2015 |
[Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].
Topics: Deglutition Disorders; Duodenum; Esomeprazole; Female; Giardiasis; Humans; Hypocalcemia; Hypoparathy | 2008 |
Omeprazole and refractory hypomagnesaemia.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Chronic Disease; Female; Humans; Hypocalcemia; Hypokalem | 2008 |
[An unknown but potentially serious side effect of proton pump inhibitors: hypomagnesaemia].
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Female; Humans; Hypocalcemia; Hypokalemia; Hypoparathyro | 2009 |
Tetany secondary to the use of a proton-pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Female; Humans; Hypocalcemia; Lansoprazole; Middle Aged; Om | 2002 |
Severe hypomagnesaemia in long-term users of proton-pump inhibitors.
Topics: Aged; Female; Gastroesophageal Reflux; Humans; Hypocalcemia; Magnesium Deficiency; Male; Middle Aged | 2008 |
The stomach is the etiologic organ for immobilization-induced hypocalcemia in rats.
Topics: Animals; Female; Gastrectomy; Gastric Fundus; Gastrins; Histamine H2 Antagonists; Hypocalcemia; Immo | 1993 |