omeprazole has been researched along with Hyperoxia in 4 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the correlation between the aryl hydrocarbon receptor (AhR) and reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) of premature infants, to demonstrate the protective role of AhR against hyperoxia-induced oxidative stress in premature infants and to provide a rational basis for the use of omeprazole (OM) as a new treatment for bronchopulmonary dysplasia (BPD)." | 8.31 | Omeprazole activates aryl hydrocarbon receptor to reduce hyperoxia-induced oxidative stress in the peripheral blood mononuclear cells from premature infants. ( Bao, Z; Dong, W; Du, F; Lei, X; Liu, X; Wang, X; Yang, X; Zhao, S, 2023) |
| "Omeprazole was administered either (1) directly to the fetus, (2) to the mother or (3) after birth to the pups in different doses (2-10 or 20 mg/kg)." | 5.43 | Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury. ( Brady, P; Deprest, J; Jimenez, J; Lesage, F; Nagatomo, T; Richter, J; Salaets, T; Toelen, J; Vanoirbeek, J, 2016) |
| "Omeprazole was administered either (1) directly to the fetus, (2) to the mother or (3) after birth to the pups in different doses (2-10 or 20 mg/kg)." | 1.43 | Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury. ( Brady, P; Deprest, J; Jimenez, J; Lesage, F; Nagatomo, T; Richter, J; Salaets, T; Toelen, J; Vanoirbeek, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, X | 1 |
| Bao, Z | 1 |
| Lei, X | 1 |
| Wang, X | 1 |
| Zhao, S | 1 |
| Du, F | 1 |
| Liu, X | 1 |
| Dong, W | 1 |
| Richter, J | 1 |
| Jimenez, J | 1 |
| Nagatomo, T | 1 |
| Toelen, J | 1 |
| Brady, P | 1 |
| Salaets, T | 1 |
| Lesage, F | 1 |
| Vanoirbeek, J | 1 |
| Deprest, J | 1 |
| Shivanna, B | 2 |
| Jiang, W | 2 |
| Wang, L | 2 |
| Couroucli, XI | 2 |
| Moorthy, B | 2 |
| Chu, C | 1 |
| Welty, SE | 1 |
4 other studies available for omeprazole and Hyperoxia
| Article | Year |
|---|---|
Omeprazole activates aryl hydrocarbon receptor to reduce hyperoxia-induced oxidative stress in the peripheral blood mononuclear cells from premature infants.
Topics: Humans; Hyperoxia; Infant; Infant, Newborn; Infant, Premature; Leukocytes, Mononuclear; Lung; Omepra | 2023 |
Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury.
Topics: Animals; Animals, Newborn; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Down-Regulatio | 2016 |
Omeprazole attenuates hyperoxic lung injury in mice via aryl hydrocarbon receptor activation and is associated with increased expression of cytochrome P4501A enzymes.
Topics: Acute Lung Injury; Animals; Blotting, Western; Chemokine CCL2; Cytochrome P-450 Enzyme System; Enzym | 2011 |
Omeprazole attenuates hyperoxic injury in H441 cells via the aryl hydrocarbon receptor.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Cell Survival; Chemokine CCL2; Cytoprotection; Epithelia | 2011 |