omeprazole has been researched along with Hernias, Diaphragmatic, Congenital in 1 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Hernias, Diaphragmatic, Congenital: Protrusion of abdominal structures into the THORAX as a result of embryologic defects in the DIAPHRAGM often present in the neonatal period. It can be isolated, syndromic, non-syndromic or be a part of chromosome abnormality. Associated pulmonary hypoplasia and PULMONARY HYPERTENSION can further complicate stabilization and surgical intervention.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Omeprazole is a proton pump inhibitor that is used in acid suppression therapy in infants." | 6.94 | Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial. ( Bestebreurtje, P; de Koning, BAE; de Wildt, SN; Knibbe, CAJ; Plötz, FB; Roeleveld, N; Tibboel, D; van de Ven, CP; van Groen, B, 2020) |
| "Omeprazole is a proton pump inhibitor that is used in acid suppression therapy in infants." | 2.94 | Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial. ( Bestebreurtje, P; de Koning, BAE; de Wildt, SN; Knibbe, CAJ; Plötz, FB; Roeleveld, N; Tibboel, D; van de Ven, CP; van Groen, B, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bestebreurtje, P | 1 |
| de Koning, BAE | 1 |
| Roeleveld, N | 1 |
| Knibbe, CAJ | 1 |
| Tibboel, D | 1 |
| van Groen, B | 1 |
| van de Ven, CP | 1 |
| Plötz, FB | 1 |
| de Wildt, SN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rectal and Oral Omeprazole Treatment of Gastroesophageal Reflux in Infants With Esophageal Atresia or Congenital Diaphragmatic Hernia; A Pharmacodynamic and Pharmacokinetic Study.[NCT00226044] | Phase 3 | 17 participants (Actual) | Interventional | 2005-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for omeprazole and Hernias, Diaphragmatic, Congenital
| Article | Year |
|---|---|
Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial.
Topics: Administration, Oral; Administration, Rectal; Esophageal Atresia; Esophageal pH Monitoring; Female; | 2020 |