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omeprazole and Hemorrhagic Shock

omeprazole has been researched along with Hemorrhagic Shock in 6 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of omeprazole in preventing gastric mucosal injury induced by hemorrhagic shock in rats and the putative mechanisms involved in this effect were investigated in the present study."7.69Protective action of omeprazole against gastric mucosal injury induced by hemorrhagic shock in rats. ( Blandizzi, C; Del Tacca, M; Gherardi, G; Marveggio, C; Natale, G, 1994)
"The determinants of gastric aminopyrine clearance were studied in a canine hemorrhagic shock model."7.67Induction of anacidity restores gastric aminopyrine clearance in canine hemorrhagic shock. ( Blum, AL; Fimmel, CJ; Hinder, RA, 1988)
"In this retrospective study, high-dose omeprazole reduced the occurrence of rebleeding, need for surgery and mortality due to hemorrhagic shock in patients with high-risk peptic ulcer bleeding, as compared with standard-dose omeprazole."3.74Continuous infusion of high-dose omeprazole is more effective than standard-dose omeprazole in patients with high-risk peptic ulcer bleeding: a retrospective study. ( Bernard-Chabert, B; DI Martino, V; Massard, J; Poynard, T; Ratziu, V; Simon-Rudler, M; Thabut, D, 2007)
" Three models of acute gastric damage (ethanol, hemorrhagic shock, and indomethacin) were examined and treatment was also carried out with the antiulcer drugs omeprazole, ranitidine, and misoprostol, to show the advantages of this histomorphometric approach."3.71Seriate histomorphometry of whole rat stomach: an accurate and reliable method for quantitative analysis of mucosal damage. ( Blandizzi, C; Del Tacca, M; Gherardi, G; Lazzeri, G; Lenzi, P; Natale, G; Pellegrini, A, 2001)
"The protective effects of the proton pump inhibitor lansoprazole on gastric mucosal damage induced by ethanol-HCl or hemorrhagic shock were investigated in the present study."3.70Acid-independent gastroprotective effects of lansoprazole in experimental mucosal injury. ( Blandizzi, C; Carignani, D; Colucci, R; Del Tacca, M; Gherardi, G; Lazzeri, G; Marveggio, C; Natale, G, 1999)
"The efficacy of omeprazole in preventing gastric mucosal injury induced by hemorrhagic shock in rats and the putative mechanisms involved in this effect were investigated in the present study."3.69Protective action of omeprazole against gastric mucosal injury induced by hemorrhagic shock in rats. ( Blandizzi, C; Del Tacca, M; Gherardi, G; Marveggio, C; Natale, G, 1994)
"The determinants of gastric aminopyrine clearance were studied in a canine hemorrhagic shock model."3.67Induction of anacidity restores gastric aminopyrine clearance in canine hemorrhagic shock. ( Blum, AL; Fimmel, CJ; Hinder, RA, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simon-Rudler, M1
Massard, J1
Bernard-Chabert, B1
DI Martino, V1
Ratziu, V1
Poynard, T1
Thabut, D1
Blandizzi, C3
Gherardi, G3
Natale, G3
Marveggio, C2
Del Tacca, M3
Benoit, R1
Grobost, O1
Lazzeri, G2
Colucci, R1
Carignani, D1
Lenzi, P1
Pellegrini, A1
Fimmel, CJ1
Hinder, RA1
Blum, AL1

Reviews

1 review available for omeprazole and Hemorrhagic Shock

ArticleYear
[Black esophagus related to acute esophageal necrosis: a new case].
    Presse medicale (Paris, France : 1983), 1999, Sep-25, Volume: 28, Issue:28

    Topics: Acute Disease; Anti-Ulcer Agents; Combined Modality Therapy; Duodenal Ulcer; Esophagoscopy; Esophagu

1999

Other Studies

5 other studies available for omeprazole and Hemorrhagic Shock

ArticleYear
Continuous infusion of high-dose omeprazole is more effective than standard-dose omeprazole in patients with high-risk peptic ulcer bleeding: a retrospective study.
    Alimentary pharmacology & therapeutics, 2007, Apr-15, Volume: 25, Issue:8

    Topics: Aged; Anti-Ulcer Agents; Blood Transfusion; Dose-Response Relationship, Drug; Endoscopy, Gastrointes

2007
Protective action of omeprazole against gastric mucosal injury induced by hemorrhagic shock in rats.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:10

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gastric Aci

1994
Acid-independent gastroprotective effects of lansoprazole in experimental mucosal injury.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Ethanol; Gastric Acid; Gastric

1999
Seriate histomorphometry of whole rat stomach: an accurate and reliable method for quantitative analysis of mucosal damage.
    Toxicology and applied pharmacology, 2001, Jul-01, Volume: 174, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Gastric Mucosa; Indomethacin; Male; Mis

2001
Induction of anacidity restores gastric aminopyrine clearance in canine hemorrhagic shock.
    Digestion, 1988, Volume: 40, Issue:1

    Topics: Aminopyrine; Animals; Disease Models, Animal; Dogs; Female; Gastric Acid; Gastric Mucosa; Male; Omep

1988