omeprazole has been researched along with Headache in 14 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
Excerpt | Relevance | Reference |
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"As can be expected, headache was reported less frequently in this study compared with clinical trials with lansoprazole." | 9.10 | Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study. ( Claessens, AA; Heerdink, ER; Lamers, CB; Leufkens, HG; van Eijk, JT, 2002) |
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer." | 9.09 | Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001) |
"To examine dyspepsia symptom relief over 16 weeks and compare an omeprazole clinical management strategy with a commonly used combination of antacid-alginate followed by H2-antagonist." | 9.08 | The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected]. ( Evans, WM; Mason, I; Millar, LJ; Sheikh, RR; Taylor, MD; Todd, PL; Turbitt, ML, 1998) |
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated." | 6.71 | Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005) |
"As can be expected, headache was reported less frequently in this study compared with clinical trials with lansoprazole." | 5.10 | Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study. ( Claessens, AA; Heerdink, ER; Lamers, CB; Leufkens, HG; van Eijk, JT, 2002) |
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer." | 5.09 | Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001) |
"To examine dyspepsia symptom relief over 16 weeks and compare an omeprazole clinical management strategy with a commonly used combination of antacid-alginate followed by H2-antagonist." | 5.08 | The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected]. ( Evans, WM; Mason, I; Millar, LJ; Sheikh, RR; Taylor, MD; Todd, PL; Turbitt, ML, 1998) |
" The most common adverse events of headache, diarrhea, and nausea have been reported in fewer than 5% of patients treated with lansoprazole or omeprazole." | 4.80 | Safety profile of the proton-pump inhibitors. ( Reilly, JP, 1999) |
"Nelfinavir was well tolerated when administered alone and when coadministered with omeprazole." | 2.73 | Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects. ( Crownover, PH; Damle, BD; Fang, AF; Glue, PW; Hewlett, D; LaBadie, RR, 2008) |
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated." | 2.71 | Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005) |
"Lansoprazole is a H+." | 2.68 | Lansoprazole versus ranitidine for the treatment of reflux oesophagitis. UK Lansoprazole Clinical Research Group. ( Bardhan, KD; Brocklebank, D; Hawkey, CJ; Long, RG; Morgan, AG; Moules, IK; Wormsley, KG, 1995) |
"To estimate the rates of common adverse events in patients treated with the proton pump inhibitors omeprazole, lansoprazole and pantoprazole in general practice in England." | 1.31 | The rates of common adverse events reported during treatment with proton pump inhibitors used in general practice in England: cohort studies. ( Dunn, NR; Freemantle, S; Martin, RM; Shakir, S, 2000) |
"Lansoprazole was mostly prescribed in patients with reflux oesophagitis (55." | 1.30 | A prospective follow-up study of 5669 users of lansoprazole in daily practice. ( Claessens, A; Heerdink, E; Lamers, CB; Leufkens, H; van Eijk, J, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (50.00) | 18.2507 |
2000's | 7 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Vakily, M | 1 |
Amer, F | 1 |
Kukulka, MJ | 1 |
Andhivarothai, N | 1 |
Huntoon, MA | 1 |
Watson, JC | 1 |
Singh, K | 1 |
Dickinson, L | 1 |
Chaikan, A | 1 |
Back, D | 1 |
Fletcher, C | 1 |
Pozniak, A | 1 |
Moyle, G | 1 |
Nelson, M | 1 |
Gazzard, B | 1 |
Herath, D | 1 |
Boffito, M | 1 |
Fang, AF | 1 |
Damle, BD | 1 |
LaBadie, RR | 1 |
Crownover, PH | 1 |
Hewlett, D | 1 |
Glue, PW | 1 |
Bardhan, KD | 1 |
Hawkey, CJ | 1 |
Long, RG | 1 |
Morgan, AG | 1 |
Wormsley, KG | 1 |
Moules, IK | 1 |
Brocklebank, D | 1 |
Sontag, SJ | 1 |
Schnell, TG | 1 |
Chejfec, G | 1 |
Kurucar, C | 1 |
Karpf, J | 1 |
Levine, G | 1 |
Meeuwisse, EJ | 1 |
Groen, FC | 1 |
Dees, A | 1 |
Smit, GH | 1 |
Ottervanger, JP | 1 |
Leufkens, H | 1 |
Claessens, A | 1 |
Heerdink, E | 1 |
van Eijk, J | 1 |
Lamers, CB | 2 |
Mason, I | 1 |
Millar, LJ | 1 |
Sheikh, RR | 1 |
Evans, WM | 1 |
Todd, PL | 1 |
Turbitt, ML | 1 |
Taylor, MD | 1 |
Reilly, JP | 1 |
Martin, RM | 1 |
Dunn, NR | 1 |
Freemantle, S | 1 |
Shakir, S | 1 |
Luzza, F | 1 |
Giglio, A | 1 |
Ciliberto, E | 1 |
Belmonte, A | 1 |
Cavaliere, C | 1 |
Saccà, N | 1 |
Frandina, C | 1 |
Fiocca, R | 1 |
Trimboli, V | 1 |
Pallone, F | 1 |
Claessens, AA | 1 |
Heerdink, ER | 1 |
van Eijk, JT | 1 |
Leufkens, HG | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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A Phase I, Randomized, Double-blind, Placebo- and Positive-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of Multiple Oral Doses of H008 (Carenoprazan Hydrochloride Tablets) in Healthy Volunteers[NCT05050188] | Phase 1 | 24 participants (Actual) | Interventional | 2021-06-24 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for omeprazole and Headache
Article | Year |
---|---|
Safety profile of the proton-pump inhibitors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Diarrhea; Drug Interactions; Gastric Muc | 1999 |
8 trials available for omeprazole and Headache
Article | Year |
---|---|
Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents | 2005 |
Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.
Topics: Adult; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Headache; HIV Infec | 2008 |
Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects.
Topics: Adolescent; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Li | 2008 |
Lansoprazole versus ranitidine for the treatment of reflux oesophagitis. UK Lansoprazole Clinical Research Group.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Double-Blind Method; Esophagitis, Peptic; Foll | 1995 |
Lansoprazole heals erosive reflux oesophagitis in patients with Barrett's oesophagus.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Double-Blind Method; Enzyme Inhibitors; | 1997 |
The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected].
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Alginates; Anti-Ulcer Agents; Biocompati | 1998 |
Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Bismuth; Clarit | 2001 |
Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Age Factors; Aged; Case-Control Studies; | 2002 |
5 other studies available for omeprazole and Headache
Article | Year |
---|---|
Intracranial hypotension following motor vehicle accident: an overlooked cause of post-traumatic head and neck pain?
Topics: Accidents, Traffic; Analgesics; Aspirin; Blood Patch, Epidural; Diplopia; Drug Therapy, Combination; | 2007 |
Lethargy with omeprazole.
Topics: Dizziness; Enzyme Inhibitors; Headache; Humans; Male; Middle Aged; Omeprazole; Sleep Stages | 1997 |
A prospective follow-up study of 5669 users of lansoprazole in daily practice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen | 1997 |
Rabeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adenosine Triphosphatases; Anti-Ulcer Agent | 1999 |
The rates of common adverse events reported during treatment with proton pump inhibitors used in general practice in England: cohort studies.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Adverse Drug Reaction Reporting Syst | 2000 |