omeprazole has been researched along with Gastrinoma in 22 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Gastrinoma: A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on the clinical signs, diagnosis and 8-year course in a 54-year-old female patient with myeloma and gastrinoma with liver metastasis and associated Cushing syndrome treated for the last 3 years with the new H+/K+-ATPase inhibitor omeprazole which has successfully suppressed the massive gastric acid hypersecretion." | 8.77 | [Long-term suppression of acid secretion with omeprazole use in metastatic gastrinoma]. ( Kummer, H; Schaub, N; Schlup, M; Wegmann, W, 1988) |
| "Evolution of gastrinoma tumoral mass, fasting serum gastrin concentrations, and gastric endocrine cells has been analyzed in 21 patients with the Zollinger-Ellison syndrome committed to long-term omeprazole treatment (up to 7." | 7.68 | Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment. ( Bonfils, S; Cadiot, G; Lehy, T; Mignon, M; Ruszniewski, P, 1993) |
| " Although the number of cases treated with omeprazole are too few to draw firm conclusions, it would appear that proton pump inhibitors are useful and should be considered for cases of gastrinoma managed medically." | 4.83 | Canine gastrinoma: a case study and literature review of therapeutic options. ( Hughes, SM, 2006) |
| "We report on the clinical signs, diagnosis and 8-year course in a 54-year-old female patient with myeloma and gastrinoma with liver metastasis and associated Cushing syndrome treated for the last 3 years with the new H+/K+-ATPase inhibitor omeprazole which has successfully suppressed the massive gastric acid hypersecretion." | 4.77 | [Long-term suppression of acid secretion with omeprazole use in metastatic gastrinoma]. ( Kummer, H; Schaub, N; Schlup, M; Wegmann, W, 1988) |
| "Evolution of gastrinoma tumoral mass, fasting serum gastrin concentrations, and gastric endocrine cells has been analyzed in 21 patients with the Zollinger-Ellison syndrome committed to long-term omeprazole treatment (up to 7." | 3.68 | Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment. ( Bonfils, S; Cadiot, G; Lehy, T; Mignon, M; Ruszniewski, P, 1993) |
| "Gastrinomas are gastrin-secreting pancreatic tumours rarely diagnosed in cats." | 1.72 | Combined surgical and medical management of a cat with gastrinoma. ( Mazepa, ASW; Myers-Nodes, J, 2022) |
| " Common causes were discarded and the hypomagnesaemia was attributed to chronic use of the proton pump inhibitor, omeprazole." | 1.40 | From hypomagnesaemia to Zollinger-Ellison syndrome: an adverse effect of a proton pump inhibitor. ( Braun, E; Eyal, A; Naffaa, ME; Sueissa, A, 2014) |
| "Primary lymph node gastrinomas are relatively rare in children and, to the best of our knowledge, have not previously been reported at this location." | 1.37 | Long-term follow-up of a child with primary lymph node gastrinoma and Zollinger-Ellison syndrome. ( Nazir, Z, 2011) |
| "Calcium gluconate was injected directly into the arteries supplying the pancreas and liver after standard selective angiography." | 1.33 | Localization of gastrinomas by selective intra-arterial calcium injection in patients on proton pump inhibitor or H2 receptor antagonist therapy. ( Bloom, SR; Dhillo, WS; Jackson, JE; Jayasena, CN; Lynn, JA; Meeran, K; Todd, JF, 2005) |
| "Intramucosal cysts were found in biopsies of non-polypoid gastric body mucosa in 71." | 1.31 | Intramucosal cysts in the gastric body of patients with Zollinger-Ellison syndrome. ( Aprile, MR; Azzoni, C; Bordi, C; Gibril, F; Jensen, RT, 2000) |
| "Cushing's syndrome was the result of ectopic adrenocorticotropic hormone production by a large cystic gastrin-producing tumour of the pancreatic tail." | 1.30 | Cushing's syndrome due to ectopic adrenocorticotropic hormone production by a non-metastatic gastrinoma after long-term conservative treatment of Zollinger-Ellison syndrome. ( Basenau, D; Becker, H; Horstmann, O; Raddatz, D; Ramadori, G, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Myers-Nodes, J | 1 |
| Mazepa, ASW | 1 |
| Norton, JA | 2 |
| Foster, DS | 1 |
| Blumgart, LH | 1 |
| Poultsides, GA | 1 |
| Visser, BC | 1 |
| Fraker, DL | 2 |
| Alexander, HR | 1 |
| Jensen, RT | 4 |
| Eyal, A | 1 |
| Sueissa, A | 1 |
| Braun, E | 1 |
| Naffaa, ME | 1 |
| Wong, H | 1 |
| Yau, T | 1 |
| Chan, P | 1 |
| Ng, IO | 1 |
| Chan, G | 1 |
| Hui, P | 1 |
| Law, WL | 1 |
| Lo, CM | 1 |
| Hedley, AJ | 1 |
| Epstein, RJ | 1 |
| Familiar, C | 1 |
| Antón, T | 1 |
| Moraga, I | 1 |
| Ramos, A | 1 |
| Marco, A | 1 |
| Nazir, Z | 1 |
| Scherübl, H | 1 |
| Schaaf, L | 1 |
| Raue, F | 1 |
| Faiss, S | 1 |
| Zeitz, M | 1 |
| Dhillo, WS | 1 |
| Jayasena, CN | 1 |
| Jackson, JE | 1 |
| Lynn, JA | 1 |
| Bloom, SR | 1 |
| Meeran, K | 1 |
| Todd, JF | 1 |
| Hughes, SM | 1 |
| Maton, PN | 2 |
| Cadiot, G | 1 |
| Lehy, T | 1 |
| Ruszniewski, P | 1 |
| Bonfils, S | 1 |
| Mignon, M | 1 |
| Gomez, G | 1 |
| Padilla, L | 1 |
| Udupi, V | 1 |
| Tarasova, N | 1 |
| Sundler, F | 1 |
| Townsend, CM | 1 |
| Thompson, JC | 1 |
| Greeley, GH | 1 |
| Altschul, M | 1 |
| Simpson, KW | 1 |
| Dykes, NL | 1 |
| Mauldin, EA | 1 |
| Reubi, JC | 1 |
| Cummings, JF | 1 |
| Raddatz, D | 1 |
| Horstmann, O | 1 |
| Basenau, D | 1 |
| Becker, H | 1 |
| Ramadori, G | 1 |
| Aprile, MR | 1 |
| Azzoni, C | 1 |
| Gibril, F | 1 |
| Bordi, C | 1 |
| Pisegna, JR | 1 |
| Slimak, GG | 1 |
| Metz, DC | 1 |
| Gardner, JD | 1 |
| Sakakibara, T | 1 |
| Inoue, K | 1 |
| Koizumi, T | 1 |
| Inoue, A | 1 |
| Kitanaka, H | 1 |
| Kaneko, E | 1 |
| Zuckerman, S | 1 |
| Lind, T | 1 |
| Olbe, L | 1 |
| Schaub, N | 1 |
| Schlup, M | 1 |
| Kummer, H | 1 |
| Wegmann, W | 1 |
5 reviews available for omeprazole and Gastrinoma
| Article | Year |
|---|---|
[About a case of multiple endocrine neoplasia type 1. Review of some clinical manifestations and treatment controversies].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Carcinoid Tumor; Combined Modality Therapy; Duodenal Neopla | 2011 |
Canine gastrinoma: a case study and literature review of therapeutic options.
Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents; Dog Diseases; Dogs; Fatal Outcome; Female; Gastri | 2006 |
Review article: the management of Zollinger-Ellison syndrome.
Topics: Diagnosis, Differential; Gastric Acid; Gastrinoma; Gastrins; Histamine H2 Antagonists; Humans; Hydro | 1993 |
New directions in the management of Zollinger-Ellison syndrome: a case study and review.
Topics: Adult; Combined Modality Therapy; Female; Gastrinoma; Histamine H2 Antagonists; Humans; Omeprazole; | 1989 |
[Long-term suppression of acid secretion with omeprazole use in metastatic gastrinoma].
Topics: Female; Gastric Juice; Gastrinoma; Humans; Liver Neoplasms; Middle Aged; Neoplasms, Multiple Primary | 1988 |
1 trial available for omeprazole and Gastrinoma
| Article | Year |
|---|---|
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; F | 1992 |
16 other studies available for omeprazole and Gastrinoma
| Article | Year |
|---|---|
Combined surgical and medical management of a cat with gastrinoma.
Topics: Animals; Cat Diseases; Cats; Duodenal Neoplasms; Female; Gastrinoma; Gastrins; Omeprazole; Pancreati | 2022 |
Incidence and Prognosis of Primary Gastrinomas in the Hepatobiliary Tract.
Topics: Adult; Bile Duct Neoplasms; Disease-Free Survival; Female; Gastrinoma; Gastrins; Hepatectomy; Humans | 2018 |
From hypomagnesaemia to Zollinger-Ellison syndrome: an adverse effect of a proton pump inhibitor.
Topics: Duodenal Neoplasms; Duodenal Ulcer; Gastrinoma; Humans; Magnesium; Male; Middle Aged; Omeprazole; Pe | 2014 |
PPI-delayed diagnosis of gastrinoma: oncologic victim of pharmacologic success.
Topics: Anti-Ulcer Agents; Appendectomy; Barrett Esophagus; Delayed Diagnosis; Gastrinoma; Gastroesophageal | 2010 |
Long-term follow-up of a child with primary lymph node gastrinoma and Zollinger-Ellison syndrome.
Topics: Abdominal Pain; Anti-Ulcer Agents; Child; Combined Modality Therapy; Diarrhea; Duodenal Ulcer; Follo | 2011 |
[Hereditary neuroendocrine gastroenteropancreatic tumors and multiple endocrine neoplasia type 1].
Topics: Anti-Ulcer Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormon | 2004 |
Localization of gastrinomas by selective intra-arterial calcium injection in patients on proton pump inhibitor or H2 receptor antagonist therapy.
Topics: Adult; Blood Specimen Collection; Calcium Gluconate; Female; Gastrinoma; Hepatic Veins; Histamine H2 | 2005 |
Zollinger-Ellison syndrome. Advances in treatment of gastric hypersecretion and the gastrinoma.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Blood Chemical Analysis; Combined Modali | 1994 |
Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment.
Topics: Adult; Aged; APUD Cells; Chi-Square Distribution; Chronic Disease; Female; Gastrinoma; Gastrins; Hum | 1993 |
Regulation of peptide YY homeostasis by gastric acid and gastrin.
Topics: Animals; Dogs; Famotidine; Female; Gastric Acid; Gastrinoma; Gastrins; Gastrointestinal Hormones; Ge | 1996 |
Evaluation of somatostatin analogues for the detection and treatment of gastrinoma in a dog.
Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents, Hormonal; Dog Diseases; Dogs; Dose-Response Relat | 1997 |
Cushing's syndrome due to ectopic adrenocorticotropic hormone production by a non-metastatic gastrinoma after long-term conservative treatment of Zollinger-Ellison syndrome.
Topics: Adrenocorticotropic Hormone; Aged; Anti-Ulcer Agents; Cushing Syndrome; Female; Gastrinoma; Gastrins | 1998 |
Intramucosal cysts in the gastric body of patients with Zollinger-Ellison syndrome.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biopsy; Cell Division; Cysts; Enterochromaffin Cells; Female; | 2000 |
From the Food and Drug Administration.
Topics: Antineoplastic Agents; Biological Products; Gastrinoma; Gastrointestinal Agents; Humans; Investigati | 2002 |
[A case of Zollinger-Ellison syndrome successfully treated with an H+-K+ ATPase inhibitor].
Topics: Adenosine Triphosphatases; Gastrinoma; Gastrins; H(+)-K(+)-Exchanging ATPase; Humans; Male; Middle A | 1989 |
Long-term follow up of patients with Zollinger-Ellison syndrome (ZES).
Topics: Aged; Female; Follow-Up Studies; Gastrinoma; Gastrins; Histamine H2 Antagonists; Humans; Male; Middl | 1989 |