Page last updated: 2024-11-01

omeprazole and Fistula

omeprazole has been researched along with Fistula in 3 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Fistula: Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.

Research Excerpts

ExcerptRelevanceReference
"Basal, pentagastrin- and histamine-stimulated acid secretion were measured in gastric fistula rats treated with the H+/K(+)-ATPase inhibitor, omeprazole, and the H2-receptor antagonist, ranitidine."7.68Time course of inhibition of gastric acid secretion by omeprazole and ranitidine in gastric fistula rats. ( Girma, K; Nilsson, G; Romell, B; Seensalu, R, 1990)
" One of 21 patients receiving omeprazole developed a fistula in comparison to 6 of 19 patients in the placebo group (pā€‰=ā€‰."5.20Effect of perioperative proton pump inhibitors on the incidence of pharyngocutaneous fistula after total laryngectomy: a prospective randomized controlled trial. ( Fagan, JJ; Stephenson, KA, 2015)
"Basal, pentagastrin- and histamine-stimulated acid secretion were measured in gastric fistula rats treated with the H+/K(+)-ATPase inhibitor, omeprazole, and the H2-receptor antagonist, ranitidine."3.68Time course of inhibition of gastric acid secretion by omeprazole and ranitidine in gastric fistula rats. ( Girma, K; Nilsson, G; Romell, B; Seensalu, R, 1990)
"Pretreatment with omeprazole to suppress completely gastric acid secretion in the diverted state resulted in a decline in pancreatic secretion similar to that observed after opening the GF."1.28The importance of gastric secretion in the feedback control of interdigestive and postprandial pancreatic secretion in rats. ( Bilski, J; Konturek, SJ; Krzyzek, E, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stephenson, KA1
Fagan, JJ1
Konturek, SJ1
Krzyzek, E1
Bilski, J1
Seensalu, R1
Girma, K1
Romell, B1
Nilsson, G1

Trials

1 trial available for omeprazole and Fistula

ArticleYear
Effect of perioperative proton pump inhibitors on the incidence of pharyngocutaneous fistula after total laryngectomy: a prospective randomized controlled trial.
    Head & neck, 2015, Volume: 37, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cutaneous Fistula; Double-Blind Method; Female; Fistula; Humans; Lar

2015

Other Studies

2 other studies available for omeprazole and Fistula

ArticleYear
The importance of gastric secretion in the feedback control of interdigestive and postprandial pancreatic secretion in rats.
    Regulatory peptides, 1991, Oct-01, Volume: 36, Issue:1

    Topics: Animals; Benzodiazepinones; Devazepide; Duodenum; Eating; Esters; Fistula; Gabexate; Gastric Juice;

1991
Time course of inhibition of gastric acid secretion by omeprazole and ranitidine in gastric fistula rats.
    European journal of pharmacology, 1990, May-03, Volume: 180, Issue:1

    Topics: Animals; Fistula; Gastric Acid; Gastrins; Histamine; In Vitro Techniques; Male; Omeprazole; Ranitidi

1990