omeprazole has been researched along with Experimental Hepatoma in 6 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In Experiment 2, the same experiment as Experiment 1 was performed, but the dosage of OPZ was 0 or 276 mg/kg." | 1.38 | Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action. ( Hayashi, H; Ishii, Y; Mitsumori, K; Morita, R; Shibutani, M; Shimamoto, K; Suzuki, K; Taniai, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, H | 2 |
| Shimamoto, K | 1 |
| Taniai, E | 2 |
| Ishii, Y | 1 |
| Morita, R | 2 |
| Suzuki, K | 2 |
| Shibutani, M | 2 |
| Mitsumori, K | 2 |
| Hayashi, M | 1 |
| Nakamura, D | 1 |
| Wakita, A | 1 |
| Kikuchi, H | 1 |
| Kato, H | 1 |
| Mizuno, M | 1 |
| Hossain, A | 1 |
| Ikawa, S | 1 |
| Miyazaki, J | 1 |
| Watanabe, M | 1 |
| Dzeletovic, N | 1 |
| McGuire, J | 1 |
| Daujat, M | 1 |
| Tholander, J | 1 |
| Ema, M | 1 |
| Fujii-Kuriyama, Y | 1 |
| Bergman, J | 1 |
| Maurel, P | 1 |
| Poellinger, L | 1 |
| Backlund, M | 2 |
| Johansson, I | 1 |
| Mkrtchian, S | 1 |
| Ingelman-Sundberg, M | 2 |
| Weidolf, L | 1 |
6 other studies available for omeprazole and Experimental Hepatoma
| Article | Year |
|---|---|
Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehyde Dehydrogenase 1 Family; Animals; Carcino | 2012 |
Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone.
Topics: Animals; beta-Naphthoflavone; Carbon Tetrachloride; Carcinogens; Cyclooxygenase 2; Cytochrome P-450 | 2012 |
Differences in inducibility of CYP1A1-mRNA by benzimidazole compounds between human and mouse cells: evidences of a human-specific signal transduction pathway for CYP1A1 induction.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Carcinoma, Hepatocellular; Cell Li | 1996 |
Regulation of dioxin receptor function by omeprazole.
Topics: Animals; Binding Sites; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Gene Expression Regulation, Enzy | 1997 |
Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.
Topics: Animals; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; Gene Expressi | 1997 |
Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells.
Topics: Animals; Benzimidazoles; Carbamates; Cytochrome P-450 CYP1A1; Gene Expression Regulation; Liver Neop | 1999 |