Page last updated: 2024-11-01

omeprazole and Esophagitis

omeprazole has been researched along with Esophagitis in 177 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Poliprotect proved noninferior to standard-dose omeprazole in symptomatic patients with heartburn/epigastric burning without erosive esophagitis and gastroduodenal lesions."9.69Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial. ( Annibale, B; Badiali, D; Bassotti, G; Bragazzi, MC; Ciacci, C; Cicala, M; Corazziari, ES; D'Alba, L; D'Ovidio, V; Di Sabatino, A; Gasbarrini, A; Iovino, P; Marazzato, M; Neri, M; Passaretti, S; Radocchia, G; Repici, A; Ribichini, E; Riggio, O; Schippa, S, 2023)
" Here, we compare the efficacy of the gastromucoprotective drug irsogladine with omeprazole in preventing NSAID-induced esophagitis, peptic ulcers, and small-intestinal mucosal injury in healthy subjects."9.17Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. ( Abe, Y; Higuchi, K; Inoue, T; Ishida, K; Kawakami, K; Kojima, Y; Kuramoto, T; Murano, M; Narabayashi, K; Nouda, S; Takeuchi, T; Tokioka, S; Umegaki, E; Yoda, Y, 2013)
" The primary objective was to compare the efficacy of rabeprazole (20 mg) and omeprazole (20 mg) regarding onset of heartburn control during the first 7 days of treatment in patients with erosive oesophagitis."9.12Effect of rabeprazole and omeprazole on the onset of gastro-oesophageal reflux disease symptom relief during the first seven days of treatment. ( Bytzer, P; Kennerly, P; Miller, N; Morocutti, A; Ravic, M, 2006)
"Gastro-oesophageal reflux disease patients (349) with endoscopically documented healed erosive oesophagitis (grade 0 or 1) were randomly assigned to receive pantoprazole (10, 20 or 40 mg/q."9.11Prevention of erosive oesophagitis relapse with pantoprazole. ( Bochenek, W; Fraga, P; Mack, M; Richter, JE; Sabesin, SM, 2004)
"To compare the gastric acid inhibition effects of lansoprazole 30 mg administered either intravenous or orally in erosive oesophagitis patients."9.11Intravenous and oral lansoprazole are equivalent in suppressing stimulated acid output in patient volunteers with erosive oesophagitis. ( Chiu, YL; Kovacs, TO; Lee, CQ; Metz, DC; Pilmer, BL, 2004)
"Sixty-seven patients (49 with Zollinger-Ellison syndrome [ZES], 18 without), with basal acid output (BAO) >15 mmol/h or >5 mmol/h if post-antrectomy (n = 9, all ZES), were treated with individually optimized doses of lansoprazole (7."9.11Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study. ( Hirschowitz, BI; Mohnen, J; Simmons, J, 2005)
"To compare the safety and efficacy of pantoprazole with ranitidine for the maintenance of endoscopically documented healed (grade 0 or 1) erosive oesophagitis."9.10Pantoprazole maintenance therapy prevents relapse of erosive oesophagitis. ( Bochenek, WJ; Metz, DC, 2003)
"To assess the efficacy of lansoprazole for the relief of symptoms due to gastroesophageal reflux disease (GERD) in children 1 to 11 years of age."9.10Efficacy of lansoprazole in the treatment of gastroesophageal reflux disease in children. ( Book, L; Ferry, G; Gunasekaran, T; Huang, B; Keith, R; Tolia, V, 2002)
"To evaluate the efficacy and tolerability of rabeprazole 10 mg and 20 mg versus placebo for the prevention of endoscopically demonstrable relapse in patients previously diagnosed with erosive or ulcerative gastro-oesophageal reflux disease (GORD) who had no oesophageal erosions or ulcerations at study entry."9.09Rabeprazole for the prevention of recurrent erosive or ulcerative gastro-oesophageal reflux disease. Rabeprazole Study Group. ( Birbara, C; Breiter, J; Hahne, W; Perdomo, C, 2000)
"To determine efficacy of lansoprazole, a relatively new proton pump inhibitor, on symptoms and oesophagitis in a group of children with gastro-oesophageal reflux disease refractory to H2 receptor antagonists."9.09Lansoprazole in the treatment of gastro-oesophageal reflux disease in childhood. ( Cucchiara, S; De Rosa, I; Franco, MT; Iula, VD; Salvia, G; Spadaro, R; Terrin, G, 2000)
"A total of 318 gastroesophageal reflux patients whose erosive esophagitis was healed in a comparative study of esomeprazole 40 mg, 20 mg, or omeprazole 20 mg, were randomized to maintenance therapy with once daily esomeprazole 40 mg, 20 mg, or 10 mg, or placebo in a U."9.09Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety. ( Benjamin, SB; Damico, D; Goldstein, JL; Hamelin, B; Johnson, DA; Lamet, M; Vakil, NB; Whipple, J, 2001)
"In patients with gastroesophageal reflux disease (GERD), esomeprazole, the S-isomer of omeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the racemic parent compound."9.09Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial. ( Breiter, JR; Hamelin, B; Hwang, C; Johanson, J; Kahrilas, PJ; Levine, JG; Marino, V; Maton, P; Richter, JE, 2001)
"To investigate whether pantoprazole also reduces bile reflux and whether this is paralleled by a change in oesophageal motility."9.09Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis. ( Brundler, R; Gaia, C; Gut, A; Halter, F; Inauen, W; Netzer, P, 2001)
"This randomized, double-blind, multicenter study was conducted to confirm a previous finding that lansoprazole relieves heartburn faster than omeprazole in patients with erosive esophagitis."9.09Comparing lansoprazole and omeprazole in onset of heartburn relief: results of a randomized, controlled trial in erosive esophagitis patients. ( Huang, B; Kahrilas, PJ; Kovacs, TO; Pencyla, JL; Richter, JE; Sontag, SJ, 2001)
"Six hundred and four patients with endoscopically proven oesophagitis and a recent history of heartburn were randomly assigned to receive lansoprazole 30 mg or omeprazole 20 mg daily for 4-8 weeks."9.08Rapid symptom relief in reflux oesophagitis: a comparison of lansoprazole and omeprazole. ( Mee, AS; Rowley, JL, 1996)
"Previous studies have demonstrated greater efficacy for omeprazole compared with cimetidine in patients with endoscopically verified oesophagitis, but excluded the substantial group of gastro-oesophageal reflux disease (GERD) patients with reflux symptoms but without endoscopic abnormality."9.08Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis. ( Axon, AT; Bate, CM; Emmas, CE; Green, JR; Murray, FE; Taylor, MD; Tildesley, G, 1997)
"Following endoscopy 424 patients presenting with heartburn as the predominant symptom of gastro-oesophageal reflux disease were randomized to treatment with omeprazole 20 or 10 mg once daily, or cisapride 10 mg four times daily, in a double-blind, double-dummy, parallel group, multicentre study."9.08Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. ( Barthelemy, P; Galmiche, JP; Hamelin, B, 1997)
"After endoscopy, patients without endoscopic oesophagitis were randomized to omeprazole 20 mg (Ome20), omeprazole 10 mg (Ome10) or placebo once daily for 4 weeks (n = 261) and those with oesophagitis (except circumferential/ulcerative) were randomized to receive either Ome20 or Ome10 once daily for 4 weeks (n = 277)."9.08Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole. International GORD Study Group. ( Carlsson, R; Dalväg, A; de Groot, G; Dent, J; Hatlebakk, J; Haug, K; Junghard, O; Riley, S; Sheikh, R; van Oudvorst, A; Watts, R; Wiklund, I, 1998)
"After healing and symptom relief had been obtained on open therapy with lansoprazole 30 mg daily, 103 patients with reflux oesophagitis grade 1 or 2 were randomized to maintenance therapy with lansoprazole 15 or 30 mg daily, and time until recurrence of symptoms and/or endoscopic changes was recorded."9.08Prognostic factors for relapse of reflux oesophagitis and symptoms during 12 months of therapy with lansoprazole. ( Berstad, A; Hatlebakk, JG, 1997)
" is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis."9.08Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis. ( Axon, AT; Bate, CM; Emmas, C; Green, JR; Murrays, FE; Owen, SM; Taylor, MD; Tildesley, G, 1998)
"To investigate the efficacy of daily maintenance treatment with omeprazole 10 mg in reducing the relapse rate of healed erosive oesophagitis."9.08Erosive oesophagitis: outcome of repeated long term maintenance treatment with low dose omeprazole 10 mg or placebo. ( Bardhan, KD; Bishop, A; Brooks, A; Cherian, P; D'Silva, J; Gillon, KR; Jones, RB; Morris, P; Patterson, J; Polak, J; Thompson, M; Vaishnavi, A; Wason, C, 1998)
"Lansoprazole (LAN) and omeprazole (OME) heal esophagitis effectively and to similar extents, but LAN has a faster effect on the relief of symptoms of gastroesophageal reflux."9.08Comparison of the effect of lansoprazole and omeprazole on intragastric acidity and gastroesophageal reflux in patients with gastroesophageal reflux disease. ( Hammarlund, B; Iwarzon, M; Janczewska, I; Sagar, M; Seensalu, R; Sjöstedt, S, 1998)
"Thirty-four dysphagic patients with peptic stricture and erosive esophagitis were dilated and randomized to omeprazole 20 mg every day versus H2RA (ranitidine 150 mg twice daily or famotidine 20 mg twice daily)."9.07Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis. ( Champion, G; Koehler, RE; Marks, RD; Mills, TP; Richter, JE; Rizzo, J; Spenney, JG, 1994)
"To determine whether the patients with refractory posterior laryngitis respond to treatment with omeprazole."9.07Omeprazole for the treatment of posterior laryngitis. ( Hanson, D; Kahrilas, PJ; Kamel, PL, 1994)
"Patients (106) with peptic ulceration of the oesophagus, stomach and duodenum, unresponsive to 3 or more months of high-dose treatment with ranitidine, were initially given pantoprazole (40-80 mg, p."9.07Long-term therapy with pantoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Brunner, G; Harke, U, 1994)
"Forty-two patients with peptic ulceration of the duodenum, stomach or oesophagus, who had not responded to 3 or more months of high-dose treatment with ranitidine (450 or 600 mg/day), were treated with oral lansoprazole at 30-60 mg daily."9.07An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Arnold, R; Brunner, G; Fuchs, W; Hennig, U, 1993)
"Forty-four patients with esophagitis refractory to standard H2-blocker therapy, who had healed after a 4- to 16-wk course with either 20-40 mg omeprazole or ranitidine at doses of 300-600 mg daily in a randomized double-blind study, commenced a 3-month maintenance course of therapy with 40 mg bid famotidine."9.07High-dose famotidine in the maintenance treatment of refractory esophagitis: results of a "medium-term" open study. ( Bianchi-Porro, G; Bonavina, L; Pace, F; Peracchia, A; Sangaletti, O; Termini, R; Vigneri, S, 1991)
"An intravenous formulation of lansoprazole, a proton pump inhibitor, is approved for use in patients with erosive oesophagitis who are temporarily unable to take oral lansoprazole."8.82Intravenous lansoprazole: in erosive oesophagitis. ( Dando, TM; Plosker, GL, 2004)
"To compare the safety and efficacy of pantoprazole, placebo and the H2 antagonist nizatidine in relieving symptoms in patients with erosive oesophagitis."8.82Pantoprazole provides rapid and sustained symptomatic relief in patients treated for erosive oesophagitis. ( Bochenek, WJ; Fraga, PD; Mack, ME; Metz, DC, 2004)
"Omeprazole and lansoprazole are used to treat erosive oesophagitis in the respective daily doses of 20 and 30 mg."8.81Meta-analysis of randomized controlled trials comparing standard clinical doses of omeprazole and lansoprazole in erosive oesophagitis. ( Howden, CW; Leontiadis, GI; Sharma, VK, 2001)
"Individual data from 1154 patients included in five independently conducted, randomized, long-term clinical trials of the efficacy of different dosage regimens of omeprazole, standard ranitidine treatment and placebo for the prevention of relapse of oesophagitis were pooled for this meta-analysis."8.79Prognostic factors influencing relapse of oesophagitis during maintenance therapy with antisecretory drugs: a meta-analysis of long-term omeprazole trials. ( Carlsson, R; Dent, J; Frison, L; Galmiche, JP; Lundell, L, 1997)
"Two cases of esophagitis associated with the use of alendronate are described."8.79[Alendronate-induced esophagitis. A report of 2 cases]. ( Girelli, CM; Reguzzoni, G; Rocca, F, 1997)
"To determine prospectively the dose of omeprazole needed to maintain remission of erosive oesophagitis and reflux symptoms in children."7.78Long-term maintenance treatment with omeprazole in children with healed erosive oesophagitis: a prospective study. ( Hassall, E; Henderson, C; Koletzko, S; Lundborg, P; Radke, M; Shepherd, R, 2012)
"Twenty-nine children with moderate to severe erosive oesophagitis and abnormal oesophageal bile reflux were studied before and after treatment with omeprazole 1 mg/kg per day."7.73Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole. ( Brecelj, J; Heuschkel, R; Homan, M; Orel, R, 2006)
"Heartburn was controlled on lansoprazole 30 mg/per day in 76."7.72Symptomatic and endoscopic outcome of heartburn 3-4.5 years after starting lansoprazole therapy: a prospective study of 142 patients. ( Abu Farsakh, N, 2003)
"To evaluate the cost effectiveness of on-demand treatment with esomeprazole 20mg compared with two alternative omeprazole treatment strategies for the long-term management of patients with gastro-oesophageal reflux disease (GORD) without oesophagitis."7.71Cost effectiveness of proton pump inhibitors in gastro-oesophageal reflux disease without oesophagitis: comparison of on-demand esomeprazole with conventional omeprazole strategies. ( Green, J; Higgins, A; Junghard, O; Wahlqvist, P, 2002)
" We report data from patients with refractory reflux esophagitis who were undergoing maintenance therapy with >/=20 mg omeprazole daily for a mean period of 6."7.70Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. ( Dent, J; Frame, MH; Havu, N; Klinkenberg-Knol, EC; Lloyd, D; Mitchell, B; Nelis, F; Prichard, P; Romàn, J; Snel, P; Walan, A, 2000)
"To compare the omeprazole test to ambulatory 24-h oesophageal pH monitoring in diagnosing GERD in symptomatic patients using endoscopically proven erosive oesophagitis as a gold standard."7.70The omeprazole test is as sensitive as 24-h oesophageal pH monitoring in diagnosing gastro-oesophageal reflux disease in symptomatic patients with erosive oesophagitis. ( Camargo, L; Fass, R; Fennerty, MB; Ofman, JJ; Sampliner, RE; Wendel, C, 2000)
"Forty five patients with refractory oesophagitis, defined as persisting erosive changes or ulceration despite a minimum of three months' treatment with cimetidine 3."7.68Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine. ( Bardhan, KD; Carroll, NJ; Daly, MJ; Dhande, DS; Hinchliffe, RF; Jones, RB; Morris, P; Thompson, M, 1990)
"Fifty-five patients (17 with nonerosive GERD and 38 with low-grade esophagitis) were treated with rabeprazole, 20 mg/day."6.71On-demand therapy with rabeprazole in nonerosive and erosive gastroesophageal reflux disease in clinical practice: effectiveness, health-related quality of life, and patient satisfaction. ( Argüello, L; Bastida, G; Garrigues, V; Ortiz, V; Ponce, J; Ponce, M, 2004)
" Safety for all study participants was monitored by adverse event reports and laboratory evaluations."6.70Safety of lansoprazole in the treatment of gastroesophageal reflux disease in children. ( Fitzgerald, J; Hassall, E; Huang, B; Kane, R; Pilmer, B; Tolia, V, 2002)
" Dosing was adjusted by monitoring intragastric pH, and esophagoscopy was repeated after 8-12 weeks of omeprazole treatment."6.69Histological esophagitis: clinical and histological response to omeprazole in children. ( Calenda, KA; Dayal, Y; Mobassaleh, M; Strauss, RS, 1999)
"Both omeprazole doses were significantly superior to placebo in complete endoscopic healing."6.67Two doses of omeprazole versus placebo in symptomatic erosive esophagitis: the U.S. Multicenter Study. ( Ahtaridis, G; Behar, J; Berenson, MM; Hirschowitz, BI; Holt, S; Ippoliti, AF; McCullough, A; Richter, JE; Robinson, MG; Sontag, SJ, 1992)
"Lansoprazole has a wide margin of safety and is well tolerated when administered as monotherapy in short- and long-term clinical trials."6.41Lansoprazole for maintenance of remission of erosive oesophagitis. ( Ballard, ED; Freston, JW; Huang, B; Jackson, RL, 2002)
"Poliprotect proved noninferior to standard-dose omeprazole in symptomatic patients with heartburn/epigastric burning without erosive esophagitis and gastroduodenal lesions."5.69Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial. ( Annibale, B; Badiali, D; Bassotti, G; Bragazzi, MC; Ciacci, C; Cicala, M; Corazziari, ES; D'Alba, L; D'Ovidio, V; Di Sabatino, A; Gasbarrini, A; Iovino, P; Marazzato, M; Neri, M; Passaretti, S; Radocchia, G; Repici, A; Ribichini, E; Riggio, O; Schippa, S, 2023)
"Drug-induced esophagitis is an uncommon diagnosis in the pediatric population."5.56L-arginine-induced esophagitis, report of six cases. ( Casaubón-Garcín, PR; Ferreiro-Marin, A; González-Cruz, MÁ; Parra, PR, 2020)
" It is unclear if polymyositis was triggered by interaction of the statin with omeprazole and/or gemfibrozil, or if it developed secondary to long-term use of atorvastatin only."5.39Statin-associated polymyositis following omeprazole treatment. ( Flores, RM; Kanth, R; Shah, MS, 2013)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."5.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)
"Cimetidine treatment was successful for seven years but dose reduction was followed by intractable hemorrhage which did not respond to H2-receptor antagonists."5.27Long term management of hemorrhagic esophagitis with cimetidine and omeprazole. ( Bonnin, M; Hetzel, DJ, 1986)
" Here, we compare the efficacy of the gastromucoprotective drug irsogladine with omeprazole in preventing NSAID-induced esophagitis, peptic ulcers, and small-intestinal mucosal injury in healthy subjects."5.17Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. ( Abe, Y; Higuchi, K; Inoue, T; Ishida, K; Kawakami, K; Kojima, Y; Kuramoto, T; Murano, M; Narabayashi, K; Nouda, S; Takeuchi, T; Tokioka, S; Umegaki, E; Yoda, Y, 2013)
" The primary objective was to compare the efficacy of rabeprazole (20 mg) and omeprazole (20 mg) regarding onset of heartburn control during the first 7 days of treatment in patients with erosive oesophagitis."5.12Effect of rabeprazole and omeprazole on the onset of gastro-oesophageal reflux disease symptom relief during the first seven days of treatment. ( Bytzer, P; Kennerly, P; Miller, N; Morocutti, A; Ravic, M, 2006)
"Patients with chronic GORD and oesophagitis verified at endoscopy were allocated to treatment with omeprazole (154 patients) or antireflux surgery (144)."5.12Seven-year follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitis. ( Hatlebakk, JG; Lundell, L; Malm, A; Miettinen, P; Myrvold, HE; Sutherland, I; Walan, A; Wallin, L, 2007)
"A total of 320 patients over 65 years with endoscopically diagnosed esophagitis were randomly assigned to one of the following treatments for 8 wk: (1) omeprazole 20 mg/d; (2) lansoprazole 30 mg/d; (3) pantoprazole 40 mg/d, or (4) rabeprazole 20 mg/d."5.12Comparison of four proton pump inhibitors for the short-term treatment of esophagitis in elderly patients. ( Andriulli, A; Annese, V; D'Ambrosio, LP; Di Mario, F; Franceschi, M; Leandro, G; Paris, F; Pilotto, A; Scarcelli, C; Seripa, D, 2007)
"Gastro-oesophageal reflux disease patients (349) with endoscopically documented healed erosive oesophagitis (grade 0 or 1) were randomly assigned to receive pantoprazole (10, 20 or 40 mg/q."5.11Prevention of erosive oesophagitis relapse with pantoprazole. ( Bochenek, W; Fraga, P; Mack, M; Richter, JE; Sabesin, SM, 2004)
"To compare the gastric acid inhibition effects of lansoprazole 30 mg administered either intravenous or orally in erosive oesophagitis patients."5.11Intravenous and oral lansoprazole are equivalent in suppressing stimulated acid output in patient volunteers with erosive oesophagitis. ( Chiu, YL; Kovacs, TO; Lee, CQ; Metz, DC; Pilmer, BL, 2004)
"Sixty-seven patients (49 with Zollinger-Ellison syndrome [ZES], 18 without), with basal acid output (BAO) >15 mmol/h or >5 mmol/h if post-antrectomy (n = 9, all ZES), were treated with individually optimized doses of lansoprazole (7."5.11Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study. ( Hirschowitz, BI; Mohnen, J; Simmons, J, 2005)
"To compare the safety and efficacy of pantoprazole with ranitidine for the maintenance of endoscopically documented healed (grade 0 or 1) erosive oesophagitis."5.10Pantoprazole maintenance therapy prevents relapse of erosive oesophagitis. ( Bochenek, WJ; Metz, DC, 2003)
"To assess the efficacy of lansoprazole for the relief of symptoms due to gastroesophageal reflux disease (GERD) in children 1 to 11 years of age."5.10Efficacy of lansoprazole in the treatment of gastroesophageal reflux disease in children. ( Book, L; Ferry, G; Gunasekaran, T; Huang, B; Keith, R; Tolia, V, 2002)
"Gastric and oesophageal pH were determined in 26 subjects with gastro-oesophageal reflux disease at baseline and on days 1, 2 and 8 of treatment with 20 mg omeprazole or 20 mg rabeprazole in a randomized, two-way cross-over fashion."5.10The basis for the decreased response to proton pump inhibitors in gastro-oesophageal reflux disease patients without erosive oesophagitis. ( Gallo-Torres, H; Gardner, JD; Miner, PB; Robinson, M; Sloan, S, 2003)
"A hypothesis suggesting that profound acid inhibition therapy facilitates and hastens the development of gastric glandular atrophy in patients infected with Helicobacter pylori was investigated in this randomized study comparing omeprazole therapy with antireflux surgery (ARS) for chronic gastroesophageal reflux disease (GERD)."5.09Lack of effect of acid suppression therapy on gastric atrophy. Nordic Gerd Study Group. ( Andersson, A; Hattlebakk, J; Havu, N; Janatuinen, E; Levander, K; Liedman, B; Lundell, L; Miettinen, P; Myrvold, HE; Nyström, P; Pedersen, SA; Thor, K, 1999)
"To evaluate the efficacy and tolerability of rabeprazole 10 mg and 20 mg versus placebo for the prevention of endoscopically demonstrable relapse in patients previously diagnosed with erosive or ulcerative gastro-oesophageal reflux disease (GORD) who had no oesophageal erosions or ulcerations at study entry."5.09Rabeprazole for the prevention of recurrent erosive or ulcerative gastro-oesophageal reflux disease. Rabeprazole Study Group. ( Birbara, C; Breiter, J; Hahne, W; Perdomo, C, 2000)
"To determine efficacy of lansoprazole, a relatively new proton pump inhibitor, on symptoms and oesophagitis in a group of children with gastro-oesophageal reflux disease refractory to H2 receptor antagonists."5.09Lansoprazole in the treatment of gastro-oesophageal reflux disease in childhood. ( Cucchiara, S; De Rosa, I; Franco, MT; Iula, VD; Salvia, G; Spadaro, R; Terrin, G, 2000)
"A total of 318 gastroesophageal reflux patients whose erosive esophagitis was healed in a comparative study of esomeprazole 40 mg, 20 mg, or omeprazole 20 mg, were randomized to maintenance therapy with once daily esomeprazole 40 mg, 20 mg, or 10 mg, or placebo in a U."5.09Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety. ( Benjamin, SB; Damico, D; Goldstein, JL; Hamelin, B; Johnson, DA; Lamet, M; Vakil, NB; Whipple, J, 2001)
"In patients with gastroesophageal reflux disease (GERD), esomeprazole, the S-isomer of omeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the racemic parent compound."5.09Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial. ( Breiter, JR; Hamelin, B; Hwang, C; Johanson, J; Kahrilas, PJ; Levine, JG; Marino, V; Maton, P; Richter, JE, 2001)
"To investigate whether pantoprazole also reduces bile reflux and whether this is paralleled by a change in oesophageal motility."5.09Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis. ( Brundler, R; Gaia, C; Gut, A; Halter, F; Inauen, W; Netzer, P, 2001)
"This randomized, double-blind, multicenter study was conducted to confirm a previous finding that lansoprazole relieves heartburn faster than omeprazole in patients with erosive esophagitis."5.09Comparing lansoprazole and omeprazole in onset of heartburn relief: results of a randomized, controlled trial in erosive esophagitis patients. ( Huang, B; Kahrilas, PJ; Kovacs, TO; Pencyla, JL; Richter, JE; Sontag, SJ, 2001)
"Six hundred and four patients with endoscopically proven oesophagitis and a recent history of heartburn were randomly assigned to receive lansoprazole 30 mg or omeprazole 20 mg daily for 4-8 weeks."5.08Rapid symptom relief in reflux oesophagitis: a comparison of lansoprazole and omeprazole. ( Mee, AS; Rowley, JL, 1996)
" Eighty-eight patients with healed erosive/ulcerative oesophagitis and relief of heartburn after pre-treatment with omeprazole received maintenance treatment."5.08Efficacy of a pectin-based anti-reflux agent on acid reflux and recurrence of symptoms and oesophagitis in gastro-oesophageal reflux disease. ( Aalykke, C; Havelund, T; Rasmussen, L, 1997)
"Previous studies have demonstrated greater efficacy for omeprazole compared with cimetidine in patients with endoscopically verified oesophagitis, but excluded the substantial group of gastro-oesophageal reflux disease (GERD) patients with reflux symptoms but without endoscopic abnormality."5.08Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis. ( Axon, AT; Bate, CM; Emmas, CE; Green, JR; Murray, FE; Taylor, MD; Tildesley, G, 1997)
"Following endoscopy 424 patients presenting with heartburn as the predominant symptom of gastro-oesophageal reflux disease were randomized to treatment with omeprazole 20 or 10 mg once daily, or cisapride 10 mg four times daily, in a double-blind, double-dummy, parallel group, multicentre study."5.08Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. ( Barthelemy, P; Galmiche, JP; Hamelin, B, 1997)
"After endoscopy, patients without endoscopic oesophagitis were randomized to omeprazole 20 mg (Ome20), omeprazole 10 mg (Ome10) or placebo once daily for 4 weeks (n = 261) and those with oesophagitis (except circumferential/ulcerative) were randomized to receive either Ome20 or Ome10 once daily for 4 weeks (n = 277)."5.08Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole. International GORD Study Group. ( Carlsson, R; Dalväg, A; de Groot, G; Dent, J; Hatlebakk, J; Haug, K; Junghard, O; Riley, S; Sheikh, R; van Oudvorst, A; Watts, R; Wiklund, I, 1998)
"After healing and symptom relief had been obtained on open therapy with lansoprazole 30 mg daily, 103 patients with reflux oesophagitis grade 1 or 2 were randomized to maintenance therapy with lansoprazole 15 or 30 mg daily, and time until recurrence of symptoms and/or endoscopic changes was recorded."5.08Prognostic factors for relapse of reflux oesophagitis and symptoms during 12 months of therapy with lansoprazole. ( Berstad, A; Hatlebakk, JG, 1997)
" is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis."5.08Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis. ( Axon, AT; Bate, CM; Emmas, C; Green, JR; Murrays, FE; Owen, SM; Taylor, MD; Tildesley, G, 1998)
"To investigate the efficacy of daily maintenance treatment with omeprazole 10 mg in reducing the relapse rate of healed erosive oesophagitis."5.08Erosive oesophagitis: outcome of repeated long term maintenance treatment with low dose omeprazole 10 mg or placebo. ( Bardhan, KD; Bishop, A; Brooks, A; Cherian, P; D'Silva, J; Gillon, KR; Jones, RB; Morris, P; Patterson, J; Polak, J; Thompson, M; Vaishnavi, A; Wason, C, 1998)
"Thirteen patients with esophagitis were given omeprazole for 90 days."5.08Treatment with proton pump inhibitors induces tolerance to histamine-2 receptor antagonists in Helicobacter pylori-negative patients. ( Arnestad, JS; Brenna, E; Qvigstad, G; Waldum, HL, 1998)
"Lansoprazole (LAN) and omeprazole (OME) heal esophagitis effectively and to similar extents, but LAN has a faster effect on the relief of symptoms of gastroesophageal reflux."5.08Comparison of the effect of lansoprazole and omeprazole on intragastric acidity and gastroesophageal reflux in patients with gastroesophageal reflux disease. ( Hammarlund, B; Iwarzon, M; Janczewska, I; Sagar, M; Seensalu, R; Sjöstedt, S, 1998)
"Thirty-four dysphagic patients with peptic stricture and erosive esophagitis were dilated and randomized to omeprazole 20 mg every day versus H2RA (ranitidine 150 mg twice daily or famotidine 20 mg twice daily)."5.07Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis. ( Champion, G; Koehler, RE; Marks, RD; Mills, TP; Richter, JE; Rizzo, J; Spenney, JG, 1994)
"To determine whether the patients with refractory posterior laryngitis respond to treatment with omeprazole."5.07Omeprazole for the treatment of posterior laryngitis. ( Hanson, D; Kahrilas, PJ; Kamel, PL, 1994)
"Patients (106) with peptic ulceration of the oesophagus, stomach and duodenum, unresponsive to 3 or more months of high-dose treatment with ranitidine, were initially given pantoprazole (40-80 mg, p."5.07Long-term therapy with pantoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Brunner, G; Harke, U, 1994)
"Forty-two patients with peptic ulceration of the duodenum, stomach or oesophagus, who had not responded to 3 or more months of high-dose treatment with ranitidine (450 or 600 mg/day), were treated with oral lansoprazole at 30-60 mg daily."5.07An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Arnold, R; Brunner, G; Fuchs, W; Hennig, U, 1993)
"Forty-four patients with esophagitis refractory to standard H2-blocker therapy, who had healed after a 4- to 16-wk course with either 20-40 mg omeprazole or ranitidine at doses of 300-600 mg daily in a randomized double-blind study, commenced a 3-month maintenance course of therapy with 40 mg bid famotidine."5.07High-dose famotidine in the maintenance treatment of refractory esophagitis: results of a "medium-term" open study. ( Bianchi-Porro, G; Bonavina, L; Pace, F; Peracchia, A; Sangaletti, O; Termini, R; Vigneri, S, 1991)
"An intravenous formulation of lansoprazole, a proton pump inhibitor, is approved for use in patients with erosive oesophagitis who are temporarily unable to take oral lansoprazole."4.82Intravenous lansoprazole: in erosive oesophagitis. ( Dando, TM; Plosker, GL, 2004)
"To compare the safety and efficacy of pantoprazole, placebo and the H2 antagonist nizatidine in relieving symptoms in patients with erosive oesophagitis."4.82Pantoprazole provides rapid and sustained symptomatic relief in patients treated for erosive oesophagitis. ( Bochenek, WJ; Fraga, PD; Mack, ME; Metz, DC, 2004)
" The newest PPI, esomeprazole, brings a statistically significant increase in healing of mucosal injury and symptom relief in patients with erosive esophagitis, compared with omeprazole and lansoprazole."4.81Pharmacologic management of gastroesophageal reflux disease. ( Katz, PO; Ramakrishnan, A, 2002)
"To summarize the published data on lansoprazole, a proton pump inhibitor approved by the Food and Drug Administration for use in the treatment of duodenal ulcer, erosive esophagitis, and pathologic hypersecretory conditions (e."4.79Lansoprazole: a proton pump inhibitor. ( Garnett, WR, 1996)
"Individual data from 1154 patients included in five independently conducted, randomized, long-term clinical trials of the efficacy of different dosage regimens of omeprazole, standard ranitidine treatment and placebo for the prevention of relapse of oesophagitis were pooled for this meta-analysis."4.79Prognostic factors influencing relapse of oesophagitis during maintenance therapy with antisecretory drugs: a meta-analysis of long-term omeprazole trials. ( Carlsson, R; Dent, J; Frison, L; Galmiche, JP; Lundell, L, 1997)
"Two cases of esophagitis associated with the use of alendronate are described."4.79[Alendronate-induced esophagitis. A report of 2 cases]. ( Girelli, CM; Reguzzoni, G; Rocca, F, 1997)
"After antifungal treatment with fluconazole, the patient's clinical symptoms gradually disappeared with the healing of gastric ulcer, which never recurred in this patient until 3 months after follow-up."3.91A rare case report of fungal esophagitis combined with giant gastric ulcer in an immunocompetent patient. ( Jianping, C; Juan, D; Liang, M; Liwen, Z; Yanbo, D; Yun, Z, 2019)
"Twenty-nine children with moderate to severe erosive oesophagitis and abnormal oesophageal bile reflux were studied before and after treatment with omeprazole 1 mg/kg per day."3.73Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole. ( Brecelj, J; Heuschkel, R; Homan, M; Orel, R, 2006)
"Heartburn was controlled on lansoprazole 30 mg/per day in 76."3.72Symptomatic and endoscopic outcome of heartburn 3-4.5 years after starting lansoprazole therapy: a prospective study of 142 patients. ( Abu Farsakh, N, 2003)
"To evaluate the cost effectiveness of on-demand treatment with esomeprazole 20mg compared with two alternative omeprazole treatment strategies for the long-term management of patients with gastro-oesophageal reflux disease (GORD) without oesophagitis."3.71Cost effectiveness of proton pump inhibitors in gastro-oesophageal reflux disease without oesophagitis: comparison of on-demand esomeprazole with conventional omeprazole strategies. ( Green, J; Higgins, A; Junghard, O; Wahlqvist, P, 2002)
"Patients with grade II-III oesophagitis underwent ambulatory motility/pH monitoring (using a Konigsberg catheter with four pressure transducers at 5 cm intervals) and solid bolus scintigraphy before and after treatment with omeprazole 20 mg b."3.70The effect of healing oesophagitis on oesophageal motor function as determined by oesophageal scintigraphy and ambulatory oesophageal motility/pH monitoring. ( Collins, JS; Ferguson, WR; Love, AH; McDougall, NI; McFarland, RJ; Mooney, RB, 1998)
" We report data from patients with refractory reflux esophagitis who were undergoing maintenance therapy with >/=20 mg omeprazole daily for a mean period of 6."3.70Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. ( Dent, J; Frame, MH; Havu, N; Klinkenberg-Knol, EC; Lloyd, D; Mitchell, B; Nelis, F; Prichard, P; Romàn, J; Snel, P; Walan, A, 2000)
"To compare the omeprazole test to ambulatory 24-h oesophageal pH monitoring in diagnosing GERD in symptomatic patients using endoscopically proven erosive oesophagitis as a gold standard."3.70The omeprazole test is as sensitive as 24-h oesophageal pH monitoring in diagnosing gastro-oesophageal reflux disease in symptomatic patients with erosive oesophagitis. ( Camargo, L; Fass, R; Fennerty, MB; Ofman, JJ; Sampliner, RE; Wendel, C, 2000)
"In a previous study we reported lack of improvement in oesophageal motor function after complete healing of oesophagitis achieved by treatment with omeprazole for a median duration of 12 weeks."3.69Prolonged remission of oesophagitis does not alter the magnitude of oesophageal acid exposure. ( Colin-Jones, DG; Singh, P; Taylor, RH, 1994)
"To investigate whether healing of the esophagitis was associated with an improvement in esophageal clearance function, 15 patients with endoscopic and histologically confirmed erosive esophagitis were studied both before and after 1-month treatment with 40 mg/day of omeprazole."3.69Esophageal clearance function following treatment of esophagitis. ( Bancewicz, J; Heggie, L; O'Hanrahan, T; Thompson, DG; Williams, D, 1994)
" Gastrin cells are normally inhibited by gastric acid and in this study we have examined how suppression of acid by treatment with omeprazole for 6-8 weeks influences gastrin production in patients with oesophagitis."3.68Increased tissue concentrations of the gastrin precursor in patients treated with omeprazole. ( Bridson, J; Dockray, GJ; Nemeth, J; Varro, A; Walker, R, 1992)
"Dysphonia is a significant problem in GER."2.75Effectiveness of voice therapy in reflux-related voice disorders. ( Bhatia, SJ; Gore, G; Hattiangadi, G; Keer, V; Murugesh, M; Ramesh, VS; Sandur, V; Vashani, K, 2010)
"Fifty-five patients (17 with nonerosive GERD and 38 with low-grade esophagitis) were treated with rabeprazole, 20 mg/day."2.71On-demand therapy with rabeprazole in nonerosive and erosive gastroesophageal reflux disease in clinical practice: effectiveness, health-related quality of life, and patient satisfaction. ( Argüello, L; Bastida, G; Garrigues, V; Ortiz, V; Ponce, J; Ponce, M, 2004)
" Safety for all study participants was monitored by adverse event reports and laboratory evaluations."2.70Safety of lansoprazole in the treatment of gastroesophageal reflux disease in children. ( Fitzgerald, J; Hassall, E; Huang, B; Kane, R; Pilmer, B; Tolia, V, 2002)
" Dosing was adjusted by monitoring intragastric pH, and esophagoscopy was repeated after 8-12 weeks of omeprazole treatment."2.69Histological esophagitis: clinical and histological response to omeprazole in children. ( Calenda, KA; Dayal, Y; Mobassaleh, M; Strauss, RS, 1999)
"Posttreatment clarithromycin resistance is common in patients who do not experience success with therapy."2.68Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. ( Axon, AT; Chalmers, DM; Dixon, MF; Langworthy, H; Moayyedi, P; Shanahan, K; Tompkins, DS, 1996)
"Omeprazole was superior to placebo in healing of esophagitis."2.67Macroscopic healing of esophagitis does not improve esophageal motility. ( Bondy, DC; Flowers, MA; Frei, JV; Howard, JM; McDonald, TJ; Reynolds, RP; Tilbe, K, 1994)
"Both omeprazole doses were significantly superior to placebo in complete endoscopic healing."2.67Two doses of omeprazole versus placebo in symptomatic erosive esophagitis: the U.S. Multicenter Study. ( Ahtaridis, G; Behar, J; Berenson, MM; Hirschowitz, BI; Holt, S; Ippoliti, AF; McCullough, A; Richter, JE; Robinson, MG; Sontag, SJ, 1992)
"Pediatric patients with gastroesophageal reflux disease and certain chronic comorbidities appear to have the greatest need of maintenance PPI treatment after healing of reflux esophagitis."2.46Maintenance treatment with proton pump inhibitors for reflux esophagitis in pediatric patients: a systematic literature analysis. ( Henderson, C; Illueca, M; Lundborg, P; Wernersson, B, 2010)
"Esomeprazole 40 mg was found to provide significantly higher healing rates at 4 weeks [OR 1."2.45Systematic review: standard- and double-dose proton pump inhibitors for the healing of severe erosive oesophagitis -- a mixed treatment comparison of randomized controlled trials. ( DAS, R; Edwards, SJ; Lind, T; Lundell, L, 2009)
"To review the literature on the treatment of gastroesophageal reflux disease (GERD) with emphasis on pharmacological aspects."2.43Treatment of gastroesophageal reflux disease. ( Camargos, PA; Guimarães, EV; Marguet, C, 2006)
"It has been shown that GERD has a significant impact on patients' quality of life; therefore, improvement of quality of life is one of the major goals of GERD treatment."2.42The impact of gastroesophageal reflux disease on quality of life. ( Kamolz, T; Pointner, R; Velanovich, V, 2003)
"Rabeprazole is a newer generation proton pump inhibitor that suppresses the gastric proton pump and acid secretion more rapidly than does omeprazole, lansoprazole or pantoprazole."2.42Review article: relief of symptoms in gastric acid-related diseases--correlation with acid suppression in rabeprazole treatment. ( Miner, P, 2004)
"It is more effective in treating erosive esophagitis in patients with GERD than omeprazole."2.41Esomeprazole magnesium (Nexium). ( Baker, DE, 2001)
"Esomeprazole is an effective agent in the treatment of gastroesophageal reflux disease (GERD) and erosive esophagitis."2.41Esomeprazole: update and clinical review. ( Baker, DE, 2002)
"Pantoprazole is a gastric hydrogen-potassium adenosine triphosphatase (H+/K(+)-ATPase) inhibitor."2.41Pantoprazole. ( Poole, P, 2001)
"Gastroesophageal reflux is a normal phenomenon recognized in infants as "spitting up."2.41Gastroesophageal reflux in infants and children. When to reassure and when to go further. ( Jones, AB, 2001)
"Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells."2.41An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole. ( Bown, RL, 2002)
"Lansoprazole has a wide margin of safety and is well tolerated when administered as monotherapy in short- and long-term clinical trials."2.41Lansoprazole for maintenance of remission of erosive oesophagitis. ( Ballard, ED; Freston, JW; Huang, B; Jackson, RL, 2002)
"Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion."2.40Lansoprazole. An update of its pharmacological properties and clinical efficacy in the management of acid-related disorders. ( Langtry, HD; Wilde, MI, 1997)
"Reflux esophagitis is a chronic condition and after stopping antisecretory treatment, including lansoprazole, most patients relapse in terms of symptoms and endoscopical lesions, which suggests the need for long-term treatment."2.38Treatment of gastroesophageal (acid) reflux with lansoprazole: an overview. ( Di Fede, F; Dobrilla, G, 1993)
"Omeprazole was healthcare professional (HCP)-preferred first-line treatment (60."1.72Patient journey in erosive oesophagitis: real-world perspectives from US physicians and patients. ( Atkinson, C; Brunton, S; Howden, CW; Jacob, R; Mark Fendrick, A; Pelletier, C; Spechler, SJ; Vaezi, MF, 2022)
"Drug-induced esophagitis is an uncommon diagnosis in the pediatric population."1.56L-arginine-induced esophagitis, report of six cases. ( Casaubón-Garcín, PR; Ferreiro-Marin, A; González-Cruz, MÁ; Parra, PR, 2020)
" It is unclear if polymyositis was triggered by interaction of the statin with omeprazole and/or gemfibrozil, or if it developed secondary to long-term use of atorvastatin only."1.39Statin-associated polymyositis following omeprazole treatment. ( Flores, RM; Kanth, R; Shah, MS, 2013)
" However, as with all drugs, PPIs should be dosed appropriately, and should be reserved for patients with conditions for which there is clear evidence of benefit from therapy."1.36Editorial: just how "difficult" is it to withdraw PPI treatment? ( Howden, CW; Kahrilas, PJ, 2010)
"Pre-existing nonerosive gastroesophageal reflux disease, smoking, and older age are important predictors of de novo development of erosive esophagitis."1.36De novo erosive esophagitis in duodenal ulcer patients related to pre-existing reflux symptoms, smoking, and patient age, but not to Helicobacter pylori eradication: a one-year follow-up study. ( Jonaitis, L; Kiudelis, G; Kupčinskas, J; Kupčinskas, L, 2010)
"Gastroesophageal reflux is a well-recognized complication of obesity."1.35Case reports--resolution of Barrett's disease and esophageal epithelial atypia after gastric bypass and LAP-BAND. ( Chang, CG; Perez, E, 2009)
" A retrospective review of children receiving PPI therapy continuously for 1 year or more with baseline and follow-up esophageal and gastric biopsies on treatment was conducted to assess type, frequency, and duration of PPI dosing, symptom relief, gastrin levels, histologic findings, and adverse events."1.35Long-term proton pump inhibitor use in children: a retrospective review of safety. ( Boyer, K; Tolia, V, 2008)
"To determine the role of duodenogastro-esophageal reflux (DGER) in the pathogenesis of refractory gastro-esophageal reflux disease (GERD) in children."1.34Duodenogastro-esophageal reflux in children with refractory gastro-esophageal reflux disease. ( De Greef, T; Ectors, N; Haesendonck, N; Hoffman, I; Tack, J; Tertychnyy, A, 2007)
"Oesophagitis was induced by pyloric ligation in wild-type and VR-1 deficient mice."1.33Attenuation of acid induced oesophagitis in VR-1 deficient mice. ( de la Fuente, SG; Fujino, K; Mantyh, CR; Takahashi, T; Takami, Y, 2006)
"Cough was significantly less severe in NEE adolescents than in younger children."1.33Presenting symptoms of nonerosive and erosive esophagitis in pediatric patients. ( Amer, F; Chiu, YL; Gupta, SK; Hassall, E; Heyman, MB, 2006)
"We report on two patients with schizoaffective disorder who received omeprazole in addition to clozapine because of gastrointestinal complaints."1.32Omeprazole reduces clozapine plasma concentrations. A case report. ( Bergemann, N; Frick, A; Kopitz, J, 2003)
"In refractory cases of GERD, eosinophilic esophagitis must be considered before any surgical measure."1.32Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice. ( Cury, EK; Faintuch, S; Schraibman, V, 2004)
"pylori and oesophagitis is mediated by the effect of H."1.31Should we eradicate Helicobacter pylori in patients with recurrent gastro-oesophageal reflux disease? ( Bianchi Porro, G; Pace, F, 2000)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."1.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)
"Omeprazole has shown remarkable efficacy and safety in the treatment of patients with gastroesophageal reflux disease (GERD); similarly, laparoscopic techniques have allowed less morbidity in patients undergoing fundoplication procedures."1.30Choice of long-term strategy for the management of patients with severe esophagitis: a cost-utility analysis. ( Centor, RM; Heudebert, GR; Marks, R; Wilcox, CM, 1997)
"Cytology from Barrett's esophagus can be misleading in the presence of severe inflammation."1.30Brush cytology in the diagnosis of neoplasia in Barrett's esophagus. ( Alderson, D; Hardwick, RH; Lott, M; Morgan, RJ; Warren, BF, 1997)
"Reflux esophagitis is frequently associated with peristaltic dysfunction, which increases with the severity of inflammatory lesions."1.30Healing of severe esophagitis improves esophageal peristaltic dysfunction. ( Deprez, P; Fiasse, R, 1999)
" The pharmacokinetic parameters of omeprazole were: systemic clearance, 0."1.29Pharmacokinetics of intravenous omeprazole in children. ( Andre, J; Baudouin, V; Bellaich, M; Faure, C; Jacqz-Aigrain, E; Navarro, J; Rohrlich, P, 1994)
"Oesophagitis was treated with omeprazole 40 mg/day for a median duration of 12 weeks."1.28Oesophageal motor function before and after healing of oesophagitis. ( Adamopoulos, A; Colin-Jones, DG; Singh, P; Taylor, RH, 1992)
"Cimetidine treatment was successful for seven years but dose reduction was followed by intractable hemorrhage which did not respond to H2-receptor antagonists."1.27Long term management of hemorrhagic esophagitis with cimetidine and omeprazole. ( Bonnin, M; Hetzel, DJ, 1986)

Research

Studies (177)

TimeframeStudies, this research(%)All Research%
pre-19904 (2.26)18.7374
1990's69 (38.98)18.2507
2000's84 (47.46)29.6817
2010's16 (9.04)24.3611
2020's4 (2.26)2.80

Authors

AuthorsStudies
Vaezi, MF1
Brunton, S1
Mark Fendrick, A1
Howden, CW3
Atkinson, C1
Pelletier, C1
Jacob, R1
Spechler, SJ2
Corazziari, ES1
Gasbarrini, A1
D'Alba, L1
D'Ovidio, V1
Riggio, O1
Passaretti, S1
Annibale, B1
Cicala, M1
Repici, A1
Bassotti, G1
Ciacci, C1
Di Sabatino, A1
Neri, M1
Bragazzi, MC1
Ribichini, E1
Radocchia, G1
Iovino, P1
Marazzato, M1
Schippa, S1
Badiali, D1
Roa Colomo, A1
García Robles, A1
Ruiz Escolano, E1
Levy, AN1
Ali, N1
Andrici, J1
Hamilton, MJ1
Parra, PR1
González-Cruz, MÁ1
Ferreiro-Marin, A1
Casaubón-Garcín, PR1
Liang, M1
Liwen, Z1
Juan, D1
Yun, Z1
Yanbo, D1
Jianping, C1
Mazzoleni, F1
Mazzoleni, LE1
de Magalhães Francesconi, CF1
Sander, GB1
Von Reisswitz, PS1
Milbradt, TC1
da Veiga Chaves Picon, R1
Uchoa, DM1
De Bona, LR1
Andreolla, HF1
Breyer, HP1
Spinato Torresini, R1
Ott, EA1
Wortmann, AC1
de Lucena Theil, A1
Stifft, J1
Zenker, RP1
Krumel, CF1
Michalczuk, MT1
De Araujo, A1
Canevese, AP1
Volpato, N1
da Silva, CA1
Schaefer, PG1
Titton, NF1
Longo, L1
Edelweiss, MI1
Simon, D1
Talley, NJ1
Beales, ILP1
Kanth, R1
Shah, MS1
Flores, RM1
Kuramoto, T1
Umegaki, E1
Nouda, S1
Narabayashi, K1
Kojima, Y1
Yoda, Y1
Ishida, K1
Kawakami, K1
Abe, Y1
Takeuchi, T1
Inoue, T1
Murano, M1
Tokioka, S1
Higuchi, K1
Banerjee, R1
Reddy, DN1
Castelluccio, MS1
Hermida, R1
Ayunta, H1
Manzotti, L1
Cháves, E1
Romo, R1
Perelstein, G1
Vashani, K1
Murugesh, M1
Hattiangadi, G1
Gore, G1
Keer, V1
Ramesh, VS1
Sandur, V1
Bhatia, SJ1
Edwards, SJ1
Lind, T2
Lundell, L5
DAS, R1
Vandenplas, Y1
Hauser, B1
Devreker, T1
Urbain, D1
Reynaert, H1
Cohen, H1
Tomasso, G1
Luisa Cafferata, M1
Zapata, C1
Sharma, P1
Armstrong, D1
Moraes-Filho, JP1
Blasco, C1
Corti, R1
Estape, G1
Leite Luna, L1
Ortuño, R1
Sakai, P1
Salis, G1
Taullard, D1
Trakal, E1
Valdovinos, M1
Vergara, M1
Gónzalez, O1
González F, CG1
Torres, J1
Molina U, R1
Harris, PR1
Chang, CG1
Perez, E1
Yaghoobi, M1
Padol, S1
Yuan, Y1
Hunt, RH1
de Leone, A2
Tonini, M2
Dominici, P2
Grossi, E2
Pace, F4
Kahrilas, PJ4
Illueca, M1
Wernersson, B1
Henderson, C2
Lundborg, P2
Jonaitis, L1
Kupčinskas, J1
Kiudelis, G1
Kupčinskas, L1
Bjornsson, E1
Riegler, G1
Hassall, E4
Shepherd, R1
Koletzko, S1
Radke, M1
Baker, DE2
Dabney-Smith, K1
Nam, J1
Ghazale, A1
Cai, Q1
Metz, DC3
Bochenek, WJ2
Siupsinskiene, N1
Adamonis, K1
Orr, CF1
Rowe, DB1
Tolia, V3
Fitzgerald, J1
Huang, B4
Pilmer, B1
Kane, R1
Ferry, G1
Gunasekaran, T1
Keith, R1
Book, L1
Ramaswamy, K1
Jacobson, K1
Jevon, G1
Israel, D1
Karlstadt, RG1
Walker, K1
Kamolz, T1
Pointner, R1
Velanovich, V1
Frick, A1
Kopitz, J1
Bergemann, N1
Gardner, JD1
Gallo-Torres, H1
Sloan, S1
Robinson, M1
Miner, PB1
Füessl, HS3
Orr, WC1
Abu Farsakh, N1
Cury, EK1
Schraibman, V1
Faintuch, S1
Kountouras, J1
Zavos, C1
Chatzopoulos, D1
Ponce, J1
Argüello, L1
Bastida, G1
Ponce, M1
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Garrigues, V1
Richter, JE6
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Kovacs, TO2
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Seripa, D1
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Bygum, A1
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Julián, L1
Antonio Gil Ruiz, J1
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Navarro, J1
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Berthou, F1
Carlhant, D1
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Gouerou, H1
Singh, P2
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Howard, JM1
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Flowers, MA1
McDonald, TJ1
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Garnett, WR1
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Galmiche, JP3
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Frison, L1
Girelli, CM1
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Rocca, F1
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Wilde, MI1
Rencken, IO1
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Gooding, CA1
Bate, CM2
Green, JR2
Axon, AT3
Murray, FE1
Tildesley, G2
Emmas, CE1
Taylor, MD2
Barthelemy, P1
Hamelin, B3
Borum, ML1
Cannava, M1
Moayyedi, P1
Langworthy, H1
Shanahan, K1
Tompkins, DS1
Dixon, MF1
Chalmers, DM1
Hardwick, RH1
Morgan, RJ1
Warren, BF1
Lott, M1
Alderson, D1
Franko, TG1
el-Nujumi, A1
Williams, C1
Ardill, JE1
Oien, K1
McColl, KE1
Walters, JK1
Zimmermann, AE1
Souney, PF1
Katona, BG1
Watts, R1
Riley, S1
Sheikh, R1
Hatlebakk, J1
Haug, K1
de Groot, G1
van Oudvorst, A1
Dalväg, A1
Junghard, O3
Wiklund, I1
Berstad, A1
Murrays, FE1
Owen, SM1
Emmas, C1
McDougall, NI1
Mooney, RB1
Ferguson, WR1
Collins, JS1
McFarland, RJ1
Love, AH1
Israel, DM1
Bardhan, KD2
Cherian, P1
Vaishnavi, A1
Jones, RB2
Thompson, M2
Morris, P2
Brooks, A1
D'Silva, J1
Gillon, KR1
Wason, C1
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Polak, J1
Bishop, A1
Qvigstad, G1
Arnestad, JS1
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Janczewska, I2
Sagar, M2
Sjöstedt, S1
Hammarlund, B1
Iwarzon, M1
Seensalu, R2
Deprez, P1
Fiasse, R1
Strauss, RS1
Calenda, KA1
Dayal, Y1
Mobassaleh, M1
Bloom, BS1
Hillman, AL1
LaMont, B1
Liss, C1
Schwartz, JS1
Stever, GJ1
Ljungdahl, A1
Bertilsson, L1
Glise, H1
Lauritsen, K1
Pedersen, SA2
Anker-Hansen, O1
Stubberöd, A1
Eriksson, G1
Cockayne, SE1
Glet, RJ1
Gawkrodger, DJ1
McDonagh, AJ1
Thor, K1
Andersson, A1
Hattlebakk, J1
Havu, N2
Janatuinen, E1
Levander, K1
Liedman, B1
Nyström, P1
Diehl, KL1
Geyer, P1
Martens, E1
Sipilä, J1
Parkkola, R1
Varpula, M1
Feldman, M1
Cryer, B1
Sammer, D1
Lee, E1
Martín de Argila, C1
Boixeda de Miquel, D1
Moreira Vicente, V1
García Plaza, A1
Klinkenberg-Knol, EC1
Nelis, F1
Snel, P1
Mitchell, B1
Prichard, P1
Lloyd, D1
Frame, MH1
Romàn, J1
Chocarro Martínez, A1
Galindo Tobal, F1
Ruiz-Irastorza, G1
González López, A1
Alvarez Navia, F1
Ochoa Sangrador, C1
Martín Arribas, MI1
Ofman, JJ1
Camargo, L1
Wendel, C1
Fennerty, MB1
Vernet Vernet, M1
Roca Figueras, G1
Jovell Fernández, E1
Iglesias Rodríguez, M1
Ureña Tapia, MM1
Roca Fusalba, A1
Bianchi Porro, G1
Birbara, C1
Breiter, J1
Perdomo, C1
Hahne, W1
Holloway, RH1
Franco, MT1
Salvia, G1
Terrin, G1
Spadaro, R1
De Rosa, I1
Iula, VD1
Cucchiara, S1
Todd, JA1
Weston, T1
MacDonald, TM1
Johnston, DA1
Dillon, JF1
Sharma, VK1
Leontiadis, GI1
Johnson, DA1
Benjamin, SB1
Vakil, NB1
Goldstein, JL1
Lamet, M1
Whipple, J1
Damico, D1
Schwetz, BA1
Johanson, J1
Maton, P1
Breiter, JR1
Marino, V1
Levine, JG1
Poole, P1
Van Biervliet, S1
Van Winckel, M1
Robberecht, E1
Kerremans, I1
Netzer, P1
Gut, A1
Brundler, R1
Gaia, C1
Halter, F1
Inauen, W1
Geboes, K1
Dekker, W1
Mulder, CJ1
Nusteling, K1
Sontag, SJ2
Pencyla, JL1
Jones, AB1
Maekawa, T1
Ohji, G1
Inoue, R1
Shimoyama, M1
Shimada, T1
Misaki, F1
Vigneri, S2
Scarpignato, C1
Savarino, V1
Lu, CL1
Chen, TS1
Chen, CY1
Chang, FY1
Kang, LJ1
Lee, SD1
Hinder, RA1
Bown, RL1
Wahlqvist, P1
Higgins, A1
Green, J1
Freston, JW1
Jackson, RL1
Ballard, ED1
Ramakrishnan, A1
Sheth, NP1
Varughese, LA1
Mazur, LJ1
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Venkatesan, P1
Kaloustian, E1
Veyssier, P1
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Bridson, J1
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Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Long-Term Study of the Efficacy and Safety of Lansoprazole in the Treatment of Zollinger-Ellison and Other Acid Hypersecretors[NCT00204373]Phase 472 participants (Actual)Interventional2003-03-31Completed
Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features in a Primary Care Setting: A Pragmatic, Randomized, Single Blind Study[NCT04028466]Phase 482 participants (Actual)Interventional2019-05-26Terminated (stopped due to Budget for the study was withdrawn and discontinued)
Capsaicin-sensitive Transient Receptor Potential Vanilloid One (TRPV1) and Tyrosine Kinase (TrkA) Receptor Expression in Children With Retrosternal Pain[NCT00677378]77 participants (Actual)Observational2006-12-31Completed
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
Proton Pump Inhibitors in the Prevention of Iron Reaccumulation in Patient With Hereditary Hemochromatosis[NCT01524757]48 participants (Anticipated)Interventional2012-03-31Not yet recruiting
Study of a Dietary Supplement for Reflux During Sleep[NCT02274636]50 participants (Anticipated)Interventional2014-10-31Not yet recruiting
A Phase I, Randomized, Double-blind, Placebo- and Positive-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of Multiple Oral Doses of H008 (Carenoprazan Hydrochloride Tablets) in Healthy Volunteers[NCT05050188]Phase 124 participants (Actual)Interventional2021-06-24Completed
Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention[NCT00413309]30 participants (Anticipated)Interventional2006-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Long-term Medical(Non-surgical)Control of Gastric Acid Production Assessed From Time of Study Enrollment, up to 240 Months Post Enrollment.

number of participants with control of gastric acid production (NCT00204373)
Timeframe: up to 240 months from study enrollment

Interventionparticipants (Number)
Single Group72

The Median Survival From the Time of Diagnosis.

The median survival from the time of diagnosis (NCT00204373)
Timeframe: survival or up to 240 months

Interventionyears (Median)
Single Group6.6

Reviews

36 reviews available for omeprazole and Esophagitis

ArticleYear
Systematic review: standard- and double-dose proton pump inhibitors for the healing of severe erosive oesophagitis -- a mixed treatment comparison of randomized controlled trials.
    Alimentary pharmacology & therapeutics, 2009, Sep-15, Volume: 30, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Esomep

2009
Latin american consensus on gastroesophageal reflux disease: an update on therapy.
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:2

    Topics: Alginates; Antacids; Anti-Ulcer Agents; Cohort Studies; Consensus; Dose-Response Relationship, Drug;

2010
Impact of oesophagitis classification in evaluating healing of erosive oesophagitis after therapy with proton pump inhibitors: a pooled analysis.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Databases, Factual; Endoscopy, Gastrointestinal; Esomeprazo

2010
Maintenance treatment with proton pump inhibitors for reflux esophagitis in pediatric patients: a systematic literature analysis.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 51, Issue:6

    Topics: Anti-Ulcer Agents; Child; Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole; Outcome Assessme

2010
Esomeprazole magnesium (Nexium).
    Reviews in gastroenterological disorders, 2001, Volume: 1, Issue:1

    Topics: Anti-Ulcer Agents; Esomeprazole; Esophagitis; Gastroesophageal Reflux; Helicobacter Infections; Huma

2001
Esomeprazole: update and clinical review.
    Reviews in gastroenterological disorders, 2002,Fall, Volume: 2, Issue:4

    Topics: Anti-Ulcer Agents; Clinical Trials as Topic; Drug Labeling; Enzyme Inhibitors; Esomeprazole; Esophag

2002
The impact of gastroesophageal reflux disease on quality of life.
    Surgical endoscopy, 2003, Volume: 17, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Combined Modality Therapy; Cross-Over St

2003
Sleep issues in gastroesophageal reflux disease: beyond simple heartburn control.
    Reviews in gastroenterological disorders, 2003, Volume: 3 Suppl 4

    Topics: Antacids; Esophagitis; Gastroesophageal Reflux; Heartburn; Humans; Omeprazole; Proton Pump Inhibitor

2003
Intravenous lansoprazole: in erosive oesophagitis.
    Drugs, 2004, Volume: 64, Issue:18

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Ulcer Agents; Clinical Trials as

2004
Review article: relief of symptoms in gastric acid-related diseases--correlation with acid suppression in rabeprazole treatment.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20 Suppl 6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Esophagitis; Gastric Aci

2004
Pantoprazole provides rapid and sustained symptomatic relief in patients treated for erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2004, Nov-15, Volume: 20, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Antacids; Anti-Ulcer Agents; Benzimidazoles; D

2004
Effectiveness of proton pump inhibitors: beyond cost.
    Reviews in gastroenterological disorders, 2004, Volume: 4 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Enzyme Inhibitors; Esophagitis; Gastroesoph

2004
Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: a meta-analysis.
    World journal of gastroenterology, 2005, Jul-14, Volume: 11, Issue:26

    Topics: Esophagitis; Histamine H2 Antagonists; Humans; Omeprazole; Proton Pump Inhibitors; Randomized Contro

2005
Treatment of gastroesophageal reflux disease.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Adult; Anti-Ulcer Agents; Barre

2006
Acid-related disorders and use of antisecretory medication.
    Danish medical bulletin, 2007, Volume: 54, Issue:1

    Topics: Anti-Ulcer Agents; Denmark; Drug Utilization; Enzyme Inhibitors; Esophagitis; Esophagoscopy; Female;

2007
Treatment of gastroesophageal (acid) reflux with lansoprazole: an overview.
    Clinical therapeutics, 1993, Volume: 15 Suppl B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Esophagitis; Gastric Acid; Gastr

1993
The medical management of gastro-oesophageal reflux.
    Drug and therapeutics bulletin, 1996, Volume: 34, Issue:1

    Topics: Anti-Ulcer Agents; Dopamine Antagonists; Esophagitis; Gastroesophageal Reflux; Histamine H2 Antagoni

1996
Lansoprazole: a proton pump inhibitor.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Interactions; Esophagitis; Humans;

1996
Prognostic factors influencing relapse of oesophagitis during maintenance therapy with antisecretory drugs: a meta-analysis of long-term omeprazole trials.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Ulcer Agents; Esophagitis; Esophagosco

1997
[Alendronate-induced esophagitis. A report of 2 cases].
    Recenti progressi in medicina, 1997, Volume: 88, Issue:5

    Topics: Alendronate; Esophagitis; Female; Humans; Middle Aged; Omeprazole; Osteoporosis, Postmenopausal; Suc

1997
Lansoprazole. An update of its pharmacological properties and clinical efficacy in the management of acid-related disorders.
    Drugs, 1997, Volume: 54, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Esophagitis; Gastrointestinal Diseases;

1997
Proton-pump inhibitors for gastric acid-related disease.
    Cleveland Clinic journal of medicine, 1998, Volume: 65, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Esophagitis; Gastric Acid; Helicobacter

1998
Omerprazole and other proton pump inhibitors: pharmacology, efficacy, and safety, with special reference to use in children.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 27, Issue:5

    Topics: Barrett Esophagus; Child; Enzyme Inhibitors; Esophagitis; Humans; Lung Diseases; Omeprazole; Peptic

1998
[Indications and use of omeprazole in esophago-gastro-duodenal diseases].
    Revista clinica espanola, 1999, Volume: 199, Issue:11

    Topics: Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Esophageal Diseases; Esophagitis; Gastritis;

1999
Endoscopy-negative reflux disease.
    Bailliere's best practice & research. Clinical gastroenterology, 2000, Volume: 14, Issue:5

    Topics: Anti-Ulcer Agents; Esophagitis; Esophagoscopy; Female; Gastroesophageal Reflux; Humans; Male; Omepra

2000
Meta-analysis of randomized controlled trials comparing standard clinical doses of omeprazole and lansoprazole in erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Esophagitis; Humans; Lansoprazole; Omepr

2001
Pantoprazole.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Jun-01, Volume: 58, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Enzyme Inhibitors; Esoph

2001
Gastroesophageal reflux in infants and children. When to reassure and when to go further.
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Child; Child, Preschool; Enzyme Inhibitors; Esophagitis; Gastroesophageal Reflux; Humans; Infant; Om

2001
Improving opportunities for effective management of gastro-oesophageal reflux disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:8

    Topics: Anti-Ulcer Agents; Biological Availability; Esomeprazole; Esophagitis; Gastric Mucosa; Gastroesophag

2001
An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole.
    International journal of clinical practice, 2002, Volume: 56, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Digestive System Diseases; Duodenal Ulcer; Dyspepsia; Enzym

2002
Lansoprazole for maintenance of remission of erosive oesophagitis.
    Drugs, 2002, Volume: 62, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Clinical Trials as Topic; Esophagitis; H

2002
Pharmacologic management of gastroesophageal reflux disease.
    Current gastroenterology reports, 2002, Volume: 4, Issue:3

    Topics: Barrett Esophagus; Esomeprazole; Esophagitis; Female; Gastroesophageal Reflux; Humans; Omeprazole; P

2002
Is omeprazole helpful in the management of children with reflux oesophagitis?
    Archives of disease in childhood, 2002, Volume: 87, Issue:1

    Topics: Esophagitis; Gastroesophageal Reflux; Humans; Infant; Male; Omeprazole; Proton Pump Inhibitors

2002
[Intragastric pH modifications induced by antisecretory treatments].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Duodenal Ulcer; Esophagitis; Gastric Acidity Determination; Gastroesophageal Reflux; Histamine H2 An

1991
[Effects of antisecretory therapy on serum gastrin and argyrophil cells of the fundus mucosa].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Cimetidine; Duodenal Ulcer; Esophagitis; Gastric Mucosa; Gastrins; Humans; Omeprazole; Ranitidine; V

1991
Therapeutic achlorhydria and risk of gastric cancer.
    Gastroenterologia Japonica, 1989, Volume: 24, Issue:5

    Topics: Animals; Biomechanical Phenomena; Carcinogens; Esophagitis; Gastric Acid; Humans; Omeprazole; Peptic

1989

Trials

49 trials available for omeprazole and Esophagitis

ArticleYear
Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial.
    The American journal of gastroenterology, 2023, 11-01, Volume: 118, Issue:11

    Topics: Abdominal Pain; Anti-Ulcer Agents; Double-Blind Method; Dyspepsia; Esophagitis; Heartburn; Humans; O

2023
Potential roles of Helicobacter pylori treatment, body mass index and waist circumference in the causation of erosive esophagitis: a randomized clinical trial (HEROES-GERD).
    International journal of obesity (2005), 2020, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; B

2020
Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study.
    BMC gastroenterology, 2013, May-14, Volume: 13

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Endoscopy, Gastrointe

2013
Effectiveness of voice therapy in reflux-related voice disorders.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2010, Volume: 23, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Dysphonia; Esophagitis; Female; Gastroesophageal Reflux; Hoarseness; Human

2010
The proton pump inhibitor test for gastroesophageal reflux disease: optimal cut-off value and duration.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2010, Volume: 42, Issue:11

    Topics: Adult; Drug Administration Schedule; Esophageal pH Monitoring; Esophagitis; Esophagoscopy; Female; G

2010
Gastroesophageal reflux disease management according to contemporary international guidelines: a translational study.
    World journal of gastroenterology, 2011, Mar-07, Volume: 17, Issue:9

    Topics: Adult; Esophagitis; Female; Gastroesophageal Reflux; Guidelines as Topic; Heartburn; Humans; Male; M

2011
Pantoprazole maintenance therapy prevents relapse of erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2003, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aluminum Hydroxide; Anti-Ulcer Agents; Benzimi

2003
Safety of lansoprazole in the treatment of gastroesophageal reflux disease in children.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Child; Child, Preschool; Dose-Response R

2002
Efficacy of lansoprazole in the treatment of gastroesophageal reflux disease in children.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Child; Child, Preschool; Endoscopy, Gast

2002
The basis for the decreased response to proton pump inhibitors in gastro-oesophageal reflux disease patients without erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2003, Nov-01, Volume: 18, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles;

2003
On-demand therapy with rabeprazole in nonerosive and erosive gastroesophageal reflux disease in clinical practice: effectiveness, health-related quality of life, and patient satisfaction.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Esophagitis; Fema

2004
Prevention of erosive oesophagitis relapse with pantoprazole.
    Alimentary pharmacology & therapeutics, 2004, Sep-01, Volume: 20, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Double-Blind Method; Eso

2004
Intravenous and oral lansoprazole are equivalent in suppressing stimulated acid output in patient volunteers with erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2004, Oct-15, Volume: 20, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Aged; Anti-Ulcer A

2004
Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Esophagitis

2005
Effect of rabeprazole and omeprazole on the onset of gastro-oesophageal reflux disease symptom relief during the first seven days of treatment.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Double-Blind Method; Enzyme Inhibitors; Esophagitis; Female

2006
Seven-year follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitis.
    The British journal of surgery, 2007, Volume: 94, Issue:2

    Topics: Aged; Anti-Ulcer Agents; Esophagitis; Female; Follow-Up Studies; Fundoplication; Gastroesophageal Re

2007
Comparison of four proton pump inhibitors for the short-term treatment of esophagitis in elderly patients.
    World journal of gastroenterology, 2007, Sep-07, Volume: 13, Issue:33

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Endoscopy, Gast

2007
Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis.
    Gastroenterology, 1994, Volume: 106, Issue:4

    Topics: Aged; Cost-Benefit Analysis; Esophageal Stenosis; Esophagitis; Female; Histamine H2 Antagonists; Hum

1994
Does long-term inhibition of gastric acid secretion with omeprazole lead to small intestinal bacterial overgrowth?
    The Netherlands journal of medicine, 1994, Volume: 45, Issue:3

    Topics: Adult; Aged; Bacteria; Breath Tests; Esophagitis; Female; Gastric Acid; Humans; Intestine, Small; Ma

1994
Macroscopic healing of esophagitis does not improve esophageal motility.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:3

    Topics: Double-Blind Method; Esophagitis; Esophagoscopy; Esophagus; Female; Humans; Male; Manometry; Middle

1994
Omeprazole for the treatment of posterior laryngitis.
    The American journal of medicine, 1994, Volume: 96, Issue:4

    Topics: Adult; Aged; Esophagitis; Female; Gastroesophageal Reflux; Humans; Laryngitis; Laryngoscopy; Male; M

1994
Long-term therapy with pantoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Duodenal Ulcer; Enterochromaffin Cells; Eso

1994
An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Drug A

1993
Rapid symptom relief in reflux oesophagitis: a comparison of lansoprazole and omeprazole.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and

1996
Efficacy of a pectin-based anti-reflux agent on acid reflux and recurrence of symptoms and oesophagitis in gastro-oesophageal reflux disease.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:5

    Topics: Aged; Anti-Ulcer Agents; Antidiarrheals; Cross-Over Studies; Double-Blind Method; Endoscopy, Digesti

1997
Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cimetidine; Double-Blind Method; Esophagitis; Female; Ga

1997
Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Enzyme Inhibitors; Esophagitis; Female; Ga

1997
Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori.
    Helicobacter, 1996, Volume: 1, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alcohol Drinking; Amoxicillin; Clarithromycin; Drug Therapy

1996
Eradicating Helicobacter pylori reduces hypergastrinaemia during long-term omeprazole treatment.
    Gut, 1998, Volume: 42, Issue:2

    Topics: Adult; Alginates; Aluminum Hydroxide; Amoxicillin; Antacids; Anti-Ulcer Agents; Drug Combinations; D

1998
Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole. International GORD Study Group.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Endoscopy; Esophagitis; Female; Fol

1998
Prognostic factors for relapse of reflux oesophagitis and symptoms during 12 months of therapy with lansoprazole.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Enzyme Inhibitors; Esophagitis; G

1997
Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:1

    Topics: Administration, Oral; Anti-Ulcer Agents; Chi-Square Distribution; Cimetidine; Double-Blind Method; E

1998
Erosive oesophagitis: outcome of repeated long term maintenance treatment with low dose omeprazole 10 mg or placebo.
    Gut, 1998, Volume: 43, Issue:4

    Topics: Anti-Ulcer Agents; Double-Blind Method; Drug Administration Schedule; Endoscopy, Gastrointestinal; E

1998
Treatment with proton pump inhibitors induces tolerance to histamine-2 receptor antagonists in Helicobacter pylori-negative patients.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:12

    Topics: Adult; Aged; Chromogranin A; Chromogranins; Drug Tolerance; Esophagitis; Female; Gastric Acid; Gastr

1998
Comparison of the effect of lansoprazole and omeprazole on intragastric acidity and gastroesophageal reflux in patients with gastroesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Cross-Over Studies; Double-Blind Method; Esoph

1998
Histological esophagitis: clinical and histological response to omeprazole in children.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:1

    Topics: Adolescent; Anti-Ulcer Agents; Child; Child, Preschool; Esophagitis; Esophagoscopy; Female; Gastrins

1999
Omeprazole or ranitidine plus metoclopramide for patients with severe erosive oesophagitis. A cost-effectiveness analysis.
    PharmacoEconomics, 1995, Volume: 8, Issue:4

    Topics: Anti-Ulcer Agents; Antiemetics; Cost-Benefit Analysis; Double-Blind Method; Drug Combinations; Esoph

1995
On demand therapy with omeprazole for the long-term management of patients with heartburn without oesophagitis--a placebo-controlled randomized trial.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Denmark; Double-Blind Method; Drug Administration Schedule; Esophagi

1999
Lack of effect of acid suppression therapy on gastric atrophy. Nordic Gerd Study Group.
    Gastroenterology, 1999, Volume: 117, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Atrophy; Esophagitis; Female; Gastric Mucosa; Gastrins;

1999
Influence of H. pylori infection on meal-stimulated gastric acid secretion and gastroesophageal acid reflux.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

1999
Rabeprazole for the prevention of recurrent erosive or ulcerative gastro-oesophageal reflux disease. Rabeprazole Study Group.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Analysis of Variance; Benzimidazoles; Dose-Res

2000
Lansoprazole in the treatment of gastro-oesophageal reflux disease in childhood.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2000, Volume: 32, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Child; Child, Preschool; Enzyme Inhibitors; Eso

2000
Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biopsy, Needle; Confidence Intervals; Dose-Res

2001
Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:3

    Topics: Adult; Aged; Double-Blind Method; Enzyme Inhibitors; Esomeprazole; Esophagitis; Female; Gastroesopha

2001
Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

2001
Long-term lansoprazole treatment for gastro-oesophageal reflux disease: clinical efficacy and influence on gastric mucosa.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Drug Administration Schedule; Endoscopy; Enzyme Inhib

2001
Comparing lansoprazole and omeprazole in onset of heartburn relief: results of a randomized, controlled trial in erosive esophagitis patients.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

2001
Two doses of omeprazole versus placebo in symptomatic erosive esophagitis: the U.S. Multicenter Study.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Dose-Response Relationship, Drug; Esophagitis; Esophagosco

1992
High-dose famotidine in the maintenance treatment of refractory esophagitis: results of a "medium-term" open study.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:11

    Topics: Adult; Double-Blind Method; Esophagitis; Esophagoscopy; Famotidine; Female; Humans; Male; Middle Age

1991

Other Studies

92 other studies available for omeprazole and Esophagitis

ArticleYear
Patient journey in erosive oesophagitis: real-world perspectives from US physicians and patients.
    BMJ open gastroenterology, 2022, Volume: 9, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Esophagitis; Gastroesoph

2022
Black esophagus, is it as bad as it seems?
    Gastroenterologia y hepatologia, 2019, Volume: 42, Issue:10

    Topics: Alcoholism; Colonic Pseudo-Obstruction; Esophagitis; Esophagoscopy; Food, Formulated; Gastrointestin

2019
It's What's Up Front That Counts-Part Two: Esophageal Crohn's Disease Complicated by Recurrent Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Adalimumab; Anti-Bacterial Agents; Anti-Inflammatory Agents; Budesonide; Colonoscopy; Colostomy; Con

2019
L-arginine-induced esophagitis, report of six cases.
    Boletin medico del Hospital Infantil de Mexico, 2020, Volume: 77, Issue:1

    Topics: Adolescent; Arginine; Chest Pain; Child; Deglutition Disorders; Esophageal Mucosa; Esophagitis; Fema

2020
A rare case report of fungal esophagitis combined with giant gastric ulcer in an immunocompetent patient.
    Medicine, 2019, Volume: 98, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Antifungal Agents; Endoscopy, Gastrointestinal; Esophagitis; Fluconazole; H

2019
Successful Treatment of Refractory Lymphocytic Esophagitis With Vedolizumab.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:9

    Topics: Adult; Antibodies, Monoclonal, Humanized; Budesonide; Deglutition Disorders; Endoscopy, Digestive Sy

2019
Statin-associated polymyositis following omeprazole treatment.
    Clinical medicine & research, 2013, Volume: 11, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Drug Interactions; Esophagitis; Gemfibrozil; Heptanoic Acids

2013
Minimal-change esophagitis on narrow-band imaging.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:8

    Topics: Endoscopy, Gastrointestinal; Esophagitis; Humans; Male; Middle Aged; Omeprazole

2008
[Upper gastrointestinal bleeding of infrequent cause].
    Acta gastroenterologica Latinoamericana, 2008, Volume: 38, Issue:2

    Topics: Acute Disease; Aged, 80 and over; Ampicillin; Anti-Ulcer Agents; Esophagitis; Fatal Outcome; Gastroi

2008
A biodegradable esophageal stent in the treatment of a corrosive esophageal stenosis in a child.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 49, Issue:2

    Topics: Absorbable Implants; Burns, Chemical; Caustics; Child; Esophageal Stenosis; Esophagitis; Esophagosco

2009
[Eosinophilic esophagitis: report of three cases].
    Revista medica de Chile, 2009, Volume: 137, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Adolescent; Child; Cyclopropanes; Eosinophilia; E

2009
Case reports--resolution of Barrett's disease and esophageal epithelial atypia after gastric bypass and LAP-BAND.
    Obesity surgery, 2009, Volume: 19, Issue:11

    Topics: Anti-Ulcer Agents; Barrett Esophagus; Esophagitis; Esophagoscopy; Gastrectomy; Gastric Bypass; Gastr

2009
Editorial: just how "difficult" is it to withdraw PPI treatment?
    The American journal of gastroenterology, 2010, Volume: 105, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dyspepsia; Esophagitis; Gastric Acid; Gastroesophageal Refl

2010
De novo erosive esophagitis in duodenal ulcer patients related to pre-existing reflux symptoms, smoking, and patient age, but not to Helicobacter pylori eradication: a one-year follow-up study.
    Medicina (Kaunas, Lithuania), 2010, Volume: 46, Issue:7

    Topics: Adult; Age Factors; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Cl

2010
It is difficult to discontinue PPI treatment in patients with GERD.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Clinical Trials as Topic; Dyspepsia; Esophagitis; Gastric A

2011
Long-term maintenance treatment with omeprazole in children with healed erosive oesophagitis: a prospective study.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagiti

2012
Severe esophagitis healed in less than a week with intravenous pantoprazole.
    Journal of clinical gastroenterology, 2003, Volume: 36, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Enzyme Inhibitors; Esophagitis; Fema

2003
Diagnostic test with omeprazole in patients with posterior laryngitis.
    Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Diet; Endoscopy, Gastrointestinal; Esophagitis; Female;

2003
Helicobacter pylori hiccup.
    Internal medicine journal, 2003, Volume: 33, Issue:3

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combinat

2003
Esophageal Crohn disease in children: a clinical spectrum.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 36, Issue:4

    Topics: Child; Child, Preschool; Colonoscopy; Crohn Disease; Endoscopy, Digestive System; Esophagitis; Esoph

2003
Update on prescribing information for pantoprazole.
    American family physician, 2003, Mar-15, Volume: 67, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Digoxin;

2003
Omeprazole reduces clozapine plasma concentrations. A case report.
    Pharmacopsychiatry, 2003, Volume: 36, Issue:3

    Topics: Adult; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Drug Antagonism; Esophagitis; Femal

2003
[Heartburn without esophagitis. Symptoms more important than the finding?].
    MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39

    Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul

2003
Symptomatic and endoscopic outcome of heartburn 3-4.5 years after starting lansoprazole therapy: a prospective study of 142 patients.
    Journal of gastroenterology, 2003, Volume: 38, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Endoscopy, Gastrointestinal; Esophagitis; Female; He

2003
Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biopsy; Child; Cimetidine; Diagnosis, Differential; Enzyme

2004
H pylori infection and reflux oesophagitis.
    Gut, 2004, Volume: 53, Issue:6

    Topics: Cohort Studies; Drug Therapy, Combination; Esophagitis; Gastroesophageal Reflux; Gastrointestinal Ag

2004
[The best strategies against reflux disease. Acid stomach and the sequelae].
    MMW Fortschritte der Medizin, 2004, Oct-28, Volume: 146, Issue:44

    Topics: Anti-Ulcer Agents; Barrett Esophagus; Chest Pain; Esophagitis; Gastroesophageal Reflux; Helicobacter

2004
Rebound acid hypersecretion after long-term inhibition of gastric acid secretion.
    Alimentary pharmacology & therapeutics, 2005, Jan-15, Volume: 21, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Antacids; Anti-Ulcer Agents; Enterochromaffin-

2005
Simultaneous herpetic and candidal esophagitis in an immunocompetent teenager.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 40, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acyclovir; Adolescent; Antifungal Agents; Antiviral Agents;

2005
Reversibility of GERD ultrastructural alterations and relief of symptoms after omeprazole treatment.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:3

    Topics: Adult; Biopsy; Epithelial Cells; Esophagitis; Female; Gastroesophageal Reflux; Heartburn; Humans; Ma

2005
Attenuation of acid induced oesophagitis in VR-1 deficient mice.
    Gut, 2006, Volume: 55, Issue:1

    Topics: Acute Disease; Animals; Anti-Ulcer Agents; Capsaicin; Endocytosis; Esophagitis; Famotidine; Hydrogen

2006
[Acid inhibitors for asthma patients].
    MMW Fortschritte der Medizin, 2005, Oct-20, Volume: 147, Issue:42

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Ulcer Agents; Asthma; Child; Eosinoph

2005
Proton pump inhibitor failure in gastro-oesophageal reflux disease--what about eosinophilic oesophagitis?
    Alimentary pharmacology & therapeutics, 2006, Apr-15, Volume: 23, Issue:8

    Topics: Adult; Eosinophilia; Esophagitis; Esophagoscopy; Gastroesophageal Reflux; Humans; Male; Omeprazole;

2006
Healing rates for moderate and severe oesophagitis.
    Alimentary pharmacology & therapeutics, 2006, May-01, Volume: 23, Issue:9

    Topics: Enzyme Inhibitors; Esophagitis; Humans; Omeprazole; Proton Pump Inhibitors; Treatment Outcome

2006
Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 42, Issue:4

    Topics: Adolescent; Anti-Ulcer Agents; Bile Reflux; Child; Child, Preschool; Esophagitis; Female; Gastroesop

2006
Presenting symptoms of nonerosive and erosive esophagitis in pediatric patients.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Anorexia; Anti-Ulcer Agents; Ch

2006
Esophageal intramural pseudodiverticulosis with esophageal strictures successfully treated with dilation therapy.
    The Annals of thoracic surgery, 2006, Volume: 82, Issue:3

    Topics: Aged; Antifungal Agents; Candidiasis; Catheterization; Chronic Disease; Deglutition Disorders; Diagn

2006
Getting categorical on GERD.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:5

    Topics: Anti-Ulcer Agents; Barrett Esophagus; Disease Progression; Esophageal Neoplasms; Esophagitis; Esopha

2007
Long-term proton pump inhibitor use in children: a retrospective review of safety.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Child; Child, Preschool; Esophagitis; Female; Gastrins; Hum

2008
Duodenogastro-esophageal reflux in children with refractory gastro-esophageal reflux disease.
    The Journal of pediatrics, 2007, Volume: 151, Issue:3

    Topics: Adolescent; Anti-Ulcer Agents; Breath Tests; Child; Duodenum; Endoscopy, Digestive System; Endoscopy

2007
Subacute cutaneous lupus erythematosus induced or exacerbated by proton pump inhibitors.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Autoantibodies; Duodenal Ulcer; Esophagitis; Female; Humans

2008
[Esophageal Crohn's disease].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Algorithms; Anti-Ulcer Agents; Crohn Disease; Cyclosporine; Endoscop

2008
Second proton-pump inhibitor marketed.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Aug-01, Volume: 52, Issue:15

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Esophagitis; Humans; Lan

1995
[Stenosing esophagitis in Zollinger-Ellison syndrome].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:11

    Topics: Esophageal Stenosis; Esophagectomy; Esophagitis; Gastrectomy; Humans; Male; Middle Aged; Omeprazole;

1994
Treatment of pyrosis does not insure adequate control of gastric acid reflux.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:4

    Topics: Barrett Esophagus; Chronic Disease; Esophagitis; Gastroesophageal Reflux; Heartburn; Humans; Hydroge

1995
Long-term treatment of erosive esophagitis with omeprazole: does it work?
    Gastroenterology, 1995, Volume: 108, Issue:2

    Topics: Administration, Oral; Cohort Studies; Drug Administration Schedule; Esophagitis; Follow-Up Studies;

1995
Pharmacokinetics of intravenous omeprazole in children.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Critical Illness; Esophagitis; Gastric Acidity Determina

1994
24-hour pH monitoring in symptomatic patients without erosive esophagitis who did not respond to antireflux treatment.
    Journal of clinical gastroenterology, 1994, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Esophagitis; Esophagus; Female; Gastroesophageal

1994
Four-week treatment with omeprazole increases the metabolism of caffeine.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:3

    Topics: Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Esophagitis; Fe

1994
Prolonged remission of oesophagitis does not alter the magnitude of oesophageal acid exposure.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:1

    Topics: Adult; Aged; Esophagitis; Esophagitis, Peptic; Esophagus; Female; Humans; Hydrogen-Ion Concentration

1994
Comparison of omeprazole and famotidine on esophageal pH in patients with moderate to severe esophagitis: a cross-over study.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:5

    Topics: Adult; Aged; Esophagitis; Esophagus; Famotidine; Female; Gastric Acid; Gastroesophageal Reflux; Huma

1994
Esophageal clearance function following treatment of esophagitis.
    Gastroenterology, 1994, Volume: 106, Issue:1

    Topics: Adult; Differential Threshold; Esophagitis; Esophagogastric Junction; Esophagus; Humans; Manometry;

1994
Surgery for uncomplicated gastro-oesophageal reflux.
    Gut, 1993, Volume: 34, Issue:3

    Topics: Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole

1993
Treatment of refractory ulcerative oesophagitis with omeprazole.
    Archives of disease in childhood, 1993, Volume: 68, Issue:4

    Topics: Esophagitis; Humans; Infant; Male; Omeprazole

1993
[Efficacy and good tolerance of omeprazole in a case of refractory ulcerative esophagitis in the child].
    Archives francaises de pediatrie, 1993, Volume: 50, Issue:1

    Topics: Child, Preschool; Drug Tolerance; Esophagitis; Humans; Male; Omeprazole; Ulcer

1993
[Gastroesophageal reflux (round table I)].
    L'union medicale du Canada, 1995, Volume: 124, Issue:1

    Topics: Anti-Ulcer Agents; Diagnosis, Differential; Esophagitis; Gastric Acid; Gastroesophageal Reflux; Hist

1995
Choice of long-term strategy for the management of patients with severe esophagitis: a cost-utility analysis.
    Gastroenterology, 1997, Volume: 112, Issue:4

    Topics: Adult; Cost-Benefit Analysis; Esophagitis; Fundoplication; Health Care Costs; Humans; Markov Chains;

1997
Video time lapse endoscopy.
    Gastrointestinal endoscopy, 1997, Volume: 45, Issue:6

    Topics: Anti-Ulcer Agents; Endoscopy, Digestive System; Esophagitis; Gastroesophageal Reflux; Humans; Image

1997
Ringed esophagus (feline esophagus) in childhood.
    Pediatric radiology, 1997, Volume: 27, Issue:9

    Topics: Adolescent; Anti-Ulcer Agents; Endoscopy; Esophagitis; Esophagus; Humans; Male; Omeprazole; Radiogra

1997
Diffuse alopecia associated with omeprazole.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:9

    Topics: Alopecia; Anti-Ulcer Agents; Enzyme Inhibitors; Esophagitis; Female; Gastric Acid; Hair; Humans; Mid

1997
Brush cytology in the diagnosis of neoplasia in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1997, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cell Count; Cell Nucleus; Chromatin; C

1997
The use of omeprazole in the pediatric population.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:4

    Topics: Adolescent; Anti-Ulcer Agents; Child; Child, Preschool; Esophagitis; Female; Humans; Male; Omeprazol

1998
The effect of healing oesophagitis on oesophageal motor function as determined by oesophageal scintigraphy and ambulatory oesophageal motility/pH monitoring.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:9

    Topics: Adult; Anti-Ulcer Agents; Esophageal Motility Disorders; Esophagitis; Esophagus; Female; Humans; Hyd

1998
Healing of severe esophagitis improves esophageal peristaltic dysfunction.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Esophagitis; Esophagus; Humans; Hydrogen-Ion Concentration; Middle A

1999
Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:4

    Topics: Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme

1999
Severe erythrodermic reactions to the proton pump inhibitors omeprazole and lansoprazole.
    The British journal of dermatology, 1999, Volume: 141, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Dermatitis, Exfoliative; Drug Erup

1999
[Diagnostic omeprazole test in suspected reflux-associated chronic cough].
    Pneumologie (Stuttgart, Germany), 1999, Volume: 53, Issue:9

    Topics: Adult; Aged; Cough; Diagnosis, Differential; Enzyme Inhibitors; Esophagitis; Female; Gastroesophagea

1999
[Esophagitis complicated with angina pectoris and mediastinitis].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:19

    Topics: Angina Pectoris; Antacids; Diagnosis, Differential; Esophagitis; Esophagoscopy; Humans; Male; Medias

1996
Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa.
    Gastroenterology, 2000, Volume: 118, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Child; Drug Resist

2000
Risk factors for esophageal candidiasis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2000, Volume: 19, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Candidiasis; Case-Control Studies

2000
The omeprazole test is as sensitive as 24-h oesophageal pH monitoring in diagnosing gastro-oesophageal reflux disease in symptomatic patients with erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:4

    Topics: Adult; Aged; Anti-Ulcer Agents; Esophagitis; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion C

2000
[Analysis of indications and diagnosis of the gastroscopies requested by primary care physicians].
    Atencion primaria, 2000, Mar-15, Volume: 25, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Diagnosis, Differential; Drug

2000
Should we eradicate Helicobacter pylori in patients with recurrent gastro-oesophageal reflux disease?
    European journal of gastroenterology & hepatology, 2000, Volume: 12 Suppl 1

    Topics: Esophagitis; Gastritis; Gastroesophageal Reflux; Helicobacter Infections; Helicobacter pylori; Human

2000
The prescribing of acid suppressants prior to the endoscopic diagnosis of Barrett's oesophagus and oesophagitis.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: Antacids; Barrett Esophagus; Cimetidine; Drug Prescriptions; Endoscopy; Esophagitis; Female; Humans;

2001
From the Food and Drug Administration.
    JAMA, 2001, Apr-04, Volume: 285, Issue:13

    Topics: Anti-Ulcer Agents; Diphtheria-Tetanus-acellular Pertussis Vaccines; Epidermolysis Bullosa Dystrophic

2001
High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:9

    Topics: Digestive System Surgical Procedures; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagea

2001
Pill-induced esophagitis caused by lansoprazole.
    Journal of gastroenterology, 2001, Volume: 36, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Esophagitis; Female; Humans; Lans

2001
Treatment of erosive oesophagitis with omeprazole: a comparison with different delivery system.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:8

    Topics: Anti-Ulcer Agents; Drug Delivery Systems; Esophagitis; Gastroesophageal Reflux; Helicobacter Infecti

2001
Proton pump inhibitors or surgery for gastro-oesophageal reflux disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2002, Volume: 34, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Clinical Trials as Topic; Enzyme Inhibit

2002
Cost effectiveness of proton pump inhibitors in gastro-oesophageal reflux disease without oesophagitis: comparison of on-demand esomeprazole with conventional omeprazole strategies.
    PharmacoEconomics, 2002, Volume: 20, Issue:4

    Topics: Adult; Cost-Benefit Analysis; Enzyme Inhibitors; Esomeprazole; Esophagitis; Female; Gastroesophageal

2002
High dose Omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2002, Volume: 37, Issue:6

    Topics: Esophageal Atresia; Esophageal Stenosis; Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole

2002
Chickenpox oesophagitis and haematemesis in an immunocompetent adult.
    The Journal of infection, 2002, Volume: 44, Issue:3

    Topics: Acyclovir; Adult; Antiviral Agents; Chickenpox; Esophagitis; Hematemesis; Herpesvirus 3, Human; Huma

2002
[Severe hyponatremia: possible role of omeprazole].
    Presse medicale (Paris, France : 1983), 1992, May-23, Volume: 21, Issue:19

    Topics: Aged; Duodenal Ulcer; Esophagitis; Humans; Hyponatremia; Male; Omeprazole; Stomach Diseases

1992
Increased tissue concentrations of the gastrin precursor in patients treated with omeprazole.
    European journal of clinical investigation, 1992, Volume: 22, Issue:10

    Topics: Amino Acid Sequence; Esophagitis; Female; Gastric Mucosa; Gastrins; Humans; Male; Middle Aged; Molec

1992
Oesophageal motor function before and after healing of oesophagitis.
    Gut, 1992, Volume: 33, Issue:12

    Topics: Adult; Aged; Esophagitis; Esophagus; Female; Humans; Hydrogen-Ion Concentration; Male; Manometry; Mi

1992
Sexual disturbances during omeprazole therapy.
    Lancet (London, England), 1991, Oct-19, Volume: 338, Issue:8773

    Topics: Aged; Esophagitis; Humans; Male; Omeprazole; Priapism

1991
Omeprazole.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1991, Volume: 21, Issue:2

    Topics: Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole; Stomach Ulcer

1991
[Omeprazole: crucial progress in the treatment of esophagitis in progressive systemic scleroderma].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5

    Topics: Esophagitis; Female; Humans; Middle Aged; Omeprazole; Scleroderma, Systemic

1991
Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine.
    Gut, 1990, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Esophagitis; Female; Humans; Male; Middle Aged; Omeprazo

1990
[Advances in the knowledge of peptic-acid dependent diseases].
    Acta gastroenterologica Latinoamericana, 1989, Volume: 19, Issue:3

    Topics: Congresses as Topic; Esophagitis; Gastric Acid; Humans; Omeprazole; Peptic Ulcer

1989
Treatment of oesophagitis in scleroderma with omeprazole.
    British journal of rheumatology, 1989, Volume: 28, Issue:6

    Topics: Esophagitis; Humans; Omeprazole; Pilot Projects; Scleroderma, Systemic

1989
Long term management of hemorrhagic esophagitis with cimetidine and omeprazole.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:2

    Topics: Anemia; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Esophagitis; Gastrointestinal Hemorrhage; Hum

1986