omeprazole has been researched along with Esophageal and Gastric Varices in 12 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " All healed with further omeprazole and healing persisted with long-term administration (20 mg/day)." | 1.28 | Bleeding from staple line erosion after esophageal transection: effect of omeprazole. ( Burroughs, AK; Hobbs, KE; Kaye, GL; McCormick, PA; McIntyre, N; Siringo, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hrabovský, V | 1 |
| Mendlová, A | 1 |
| Zadák, Z | 1 |
| Bláha, V | 1 |
| Hyšpler, R | 1 |
| Tichá, A | 1 |
| Svagera, Z | 1 |
| Lo, GH | 1 |
| Perng, DS | 1 |
| Chang, CY | 1 |
| Tai, CM | 1 |
| Wang, HM | 1 |
| Lin, HC | 1 |
| Zhou, Y | 1 |
| Qiao, L | 1 |
| Wu, J | 1 |
| Hu, H | 1 |
| Xu, C | 1 |
| Yarze, JC | 1 |
| Shaheen, NJ | 1 |
| Stuart, E | 1 |
| Schmitz, SM | 1 |
| Mitchell, KL | 1 |
| Fried, MW | 1 |
| Zacks, S | 1 |
| Russo, MW | 1 |
| Galanko, J | 1 |
| Shrestha, R | 1 |
| Ashley, SW | 1 |
| Cheung, LY | 1 |
| Garg, PK | 1 |
| Sidhu, SS | 1 |
| Bhargava, DK | 1 |
| Jaspersen, D | 2 |
| Körner, T | 2 |
| Schorr, W | 2 |
| Hammar, CH | 2 |
| Tanaka, J | 1 |
| Fujimoto, K | 1 |
| Iwakiri, R | 1 |
| Koyama, T | 1 |
| Sakata, H | 1 |
| Ohyama, T | 1 |
| Mizuguchi, M | 1 |
| Tokunaga, O | 1 |
| Johlin, FC | 1 |
| Labrecque, DR | 1 |
| Neil, GA | 1 |
| Kaye, GL | 1 |
| McCormick, PA | 1 |
| Siringo, S | 1 |
| Hobbs, KE | 1 |
| McIntyre, N | 1 |
| Burroughs, AK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled Trial of Ligation Plus Vasoconstrictor vs.Ligation Plus Proton Pump Inhibitor in the Control of Acute Esophageal Variceal Bleeding[NCT01112852] | Phase 4 | 118 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| Comparative Effectiveness Research: Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails to Treat the Patients With Acute Variceal Bleeding[NCT02311608] | 1,320 participants (Anticipated) | Observational | 2014-02-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for omeprazole and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast | 2013 |
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast | 2013 |
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast | 2013 |
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast | 2013 |
Comparison of the efficacy of octreotide, vasopressin, and omeprazole in the control of acute bleeding in patients with portal hypertensive gastropathy: a controlled study.
Topics: Adult; Aged; Drug Evaluation; Enzyme Inhibitors; Esophageal and Gastric Varices; Female; Gastrointes | 2002 |
Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: a randomized, controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Double-Blind Method; Esophageal and Gastric | 2005 |
Role of omeprazole in prevention and treatment of postendoscopic variceal sclerotherapy esophageal complications. Double-blind randomized study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Esophageal and Gastric Varices; Eso | 1995 |
Omeprazole in the management of sclerotherapy-induced esophageal ulcers resistant to H2 blocker treatment.
Topics: Adult; Aged; Aged, 80 and over; Drug Resistance; Esophageal and Gastric Varices; Esophageal Diseases | 1995 |
7 other studies available for omeprazole and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations.
Topics: Acute Disease; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Combined Modal | 2012 |
Septic complications after variceal cyanoacrylate injection.
Topics: Anti-Ulcer Agents; Cyanoacrylates; Esophageal and Gastric Varices; Hemostasis, Endoscopic; Humans; O | 2005 |
The SSAT-AGA (Society for Surgery of the Alimentary Tract-American Gastroenterological Association). New Orleans, May 20-23, 1984.
Topics: Animals; Benzimidazoles; Colitis, Ulcerative; Colon; Common Bile Duct; Crohn Disease; Digestive Syst | 1984 |
Hyperplastic polyps following treatment of acute gastric ulcers.
Topics: Esophageal and Gastric Varices; Famotidine; Female; Humans; Hyperplasia; Middle Aged; Omeprazole; Po | 1994 |
[Omeprazole in H2-receptor blockader-refractory sclerosing ulcers of the esophagus].
Topics: Esophageal and Gastric Varices; Esophageal Stenosis; Humans; Omeprazole; Polidocanol; Polyethylene G | 1993 |
Omeprazole heals mucosal ulcers associated with endoscopic injection sclerotherapy.
Topics: Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Esophageal Diseases; Female; Humans; Male; M | 1992 |
Bleeding from staple line erosion after esophageal transection: effect of omeprazole.
Topics: Adult; Aged; Depression, Chemical; Drug Evaluation; Esophageal and Gastric Varices; Esophagus; Femal | 1992 |