Page last updated: 2024-11-01

omeprazole and Esophageal Varices

omeprazole has been researched along with Esophageal Varices in 12 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
" All healed with further omeprazole and healing persisted with long-term administration (20 mg/day)."1.28Bleeding from staple line erosion after esophageal transection: effect of omeprazole. ( Burroughs, AK; Hobbs, KE; Kaye, GL; McCormick, PA; McIntyre, N; Siringo, S, 1992)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's6 (50.00)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hrabovský, V1
Mendlová, A1
Zadák, Z1
Bláha, V1
Hyšpler, R1
Tichá, A1
Svagera, Z1
Lo, GH1
Perng, DS1
Chang, CY1
Tai, CM1
Wang, HM1
Lin, HC1
Zhou, Y1
Qiao, L1
Wu, J1
Hu, H1
Xu, C1
Yarze, JC1
Shaheen, NJ1
Stuart, E1
Schmitz, SM1
Mitchell, KL1
Fried, MW1
Zacks, S1
Russo, MW1
Galanko, J1
Shrestha, R1
Ashley, SW1
Cheung, LY1
Garg, PK1
Sidhu, SS1
Bhargava, DK1
Jaspersen, D2
Körner, T2
Schorr, W2
Hammar, CH2
Tanaka, J1
Fujimoto, K1
Iwakiri, R1
Koyama, T1
Sakata, H1
Ohyama, T1
Mizuguchi, M1
Tokunaga, O1
Johlin, FC1
Labrecque, DR1
Neil, GA1
Kaye, GL1
McCormick, PA1
Siringo, S1
Hobbs, KE1
McIntyre, N1
Burroughs, AK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Controlled Trial of Ligation Plus Vasoconstrictor vs.Ligation Plus Proton Pump Inhibitor in the Control of Acute Esophageal Variceal Bleeding[NCT01112852]Phase 4118 participants (Actual)Interventional2006-12-31Completed
Comparative Effectiveness Research: Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails to Treat the Patients With Acute Variceal Bleeding[NCT02311608]1,320 participants (Anticipated)Observational2014-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for omeprazole and Esophageal Varices

ArticleYear
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast

2013
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast

2013
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast

2013
Controlled trial of ligation plus vasoconstrictor versus proton pump inhibitor in the control of acute esophageal variceal bleeding.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Combined Modality Therapy; Esophageal and Gast

2013
Comparison of the efficacy of octreotide, vasopressin, and omeprazole in the control of acute bleeding in patients with portal hypertensive gastropathy: a controlled study.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:9

    Topics: Adult; Aged; Drug Evaluation; Enzyme Inhibitors; Esophageal and Gastric Varices; Female; Gastrointes

2002
Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: a randomized, controlled trial.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Double-Blind Method; Esophageal and Gastric

2005
Role of omeprazole in prevention and treatment of postendoscopic variceal sclerotherapy esophageal complications. Double-blind randomized study.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Esophageal and Gastric Varices; Eso

1995
Omeprazole in the management of sclerotherapy-induced esophageal ulcers resistant to H2 blocker treatment.
    Journal of gastroenterology, 1995, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Drug Resistance; Esophageal and Gastric Varices; Esophageal Diseases

1995

Other Studies

7 other studies available for omeprazole and Esophageal Varices

ArticleYear
Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations.
    Wiener klinische Wochenschrift, 2012, Volume: 124, Issue:23-24

    Topics: Acute Disease; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Combined Modal

2012
Septic complications after variceal cyanoacrylate injection.
    Gastrointestinal endoscopy, 2005, Volume: 61, Issue:1

    Topics: Anti-Ulcer Agents; Cyanoacrylates; Esophageal and Gastric Varices; Hemostasis, Endoscopic; Humans; O

2005
The SSAT-AGA (Society for Surgery of the Alimentary Tract-American Gastroenterological Association). New Orleans, May 20-23, 1984.
    Surgical gastroenterology, 1984, Volume: 3, Issue:2

    Topics: Animals; Benzimidazoles; Colitis, Ulcerative; Colon; Common Bile Duct; Crohn Disease; Digestive Syst

1984
Hyperplastic polyps following treatment of acute gastric ulcers.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:6

    Topics: Esophageal and Gastric Varices; Famotidine; Female; Humans; Hyperplasia; Middle Aged; Omeprazole; Po

1994
[Omeprazole in H2-receptor blockader-refractory sclerosing ulcers of the esophagus].
    Deutsche medizinische Wochenschrift (1946), 1993, May-07, Volume: 118, Issue:18

    Topics: Esophageal and Gastric Varices; Esophageal Stenosis; Humans; Omeprazole; Polidocanol; Polyethylene G

1993
Omeprazole heals mucosal ulcers associated with endoscopic injection sclerotherapy.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:9

    Topics: Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Esophageal Diseases; Female; Humans; Male; M

1992
Bleeding from staple line erosion after esophageal transection: effect of omeprazole.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:6

    Topics: Adult; Aged; Depression, Chemical; Drug Evaluation; Esophageal and Gastric Varices; Esophagus; Femal

1992