Page last updated: 2024-11-01

omeprazole and Esophageal Stricture

omeprazole has been researched along with Esophageal Stricture in 40 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Omeprazole reduced the risk of short-term developing esophageal strictures following grade 2b and 3a corrosive esophageal injuries."9.41A prospective randomized controlled trial of omeprazole for preventing esophageal stricture in grade 2b and 3a corrosive esophageal injuries. ( Awsakulsutthi, S; Boochangkool, N; Havanond, C; Mahawongkajit, P; Mingmalairak, C; Tomtitchong, P, 2021)
"Better control of gastric acid secretion with omeprazole appeared to decrease the need for dilatation of oesophageal strictures complicating gastro-oesophageal reflux disease in our hospital-based endoscopy service."9.09Omeprazole therapy decreases the need for dilatation of peptic oesophageal strictures. ( Barbezat, GO; Lubcke, R; Schlup, M, 1999)
"To determine the efficacy of lansoprazole 30 mg given in the morning compared with high-dose ranitidine 300 mg twice daily in the treatment of patients with oesophageal strictures."9.08Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine. ( Christian, J; Foster, CS; Garrett, AD; Gough, AL; Langworthy, CH; Swarbrick, ET, 1996)
"Thirty-four dysphagic patients with peptic stricture and erosive esophagitis were dilated and randomized to omeprazole 20 mg every day versus H2RA (ranitidine 150 mg twice daily or famotidine 20 mg twice daily)."9.07Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis. ( Champion, G; Koehler, RE; Marks, RD; Mills, TP; Richter, JE; Rizzo, J; Spenney, JG, 1994)
"Omeprazole reduced the risk of short-term developing esophageal strictures following grade 2b and 3a corrosive esophageal injuries."5.41A prospective randomized controlled trial of omeprazole for preventing esophageal stricture in grade 2b and 3a corrosive esophageal injuries. ( Awsakulsutthi, S; Boochangkool, N; Havanond, C; Mahawongkajit, P; Mingmalairak, C; Tomtitchong, P, 2021)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."5.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)
" After appropriate assessment with esophageal manometry and 24 h ambulatory pHmetry, patients with documented gastroesophageal reflux disease (GERD) were treated with omeprazole continuously."5.12Single-session, graded esophageal dilation without fluoroscopy in outpatients with lower esophageal (Schatzki's) rings: a prospective, long-term follow-up study. ( Bergele, C; Mantides, A; Sgouros, SN; Stefanidis, G; Vassiliadis, K; Vlachogiannakos, J, 2007)
"Better control of gastric acid secretion with omeprazole appeared to decrease the need for dilatation of oesophageal strictures complicating gastro-oesophageal reflux disease in our hospital-based endoscopy service."5.09Omeprazole therapy decreases the need for dilatation of peptic oesophageal strictures. ( Barbezat, GO; Lubcke, R; Schlup, M, 1999)
"To determine the efficacy of lansoprazole 30 mg given in the morning compared with high-dose ranitidine 300 mg twice daily in the treatment of patients with oesophageal strictures."5.08Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine. ( Christian, J; Foster, CS; Garrett, AD; Gough, AL; Langworthy, CH; Swarbrick, ET, 1996)
"In our study omeprazole was superior to either lansoprazole or pantoprazole in the maintenance treatment of complicated gastro-oesophageal reflux disease."5.08A comparison of omeprazole, lansoprazole and pantoprazole in the maintenance treatment of severe reflux oesophagitis. ( Diehl, KL; Geyer, P; Jaspersen, D; Martens, E; Schoeppner, H, 1998)
"Thirty-four dysphagic patients with peptic stricture and erosive esophagitis were dilated and randomized to omeprazole 20 mg every day versus H2RA (ranitidine 150 mg twice daily or famotidine 20 mg twice daily)."5.07Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis. ( Champion, G; Koehler, RE; Marks, RD; Mills, TP; Richter, JE; Rizzo, J; Spenney, JG, 1994)
"The height of patients may help to predict the risks and the prescription of omeprazole may help to minimize the risks of 2b and 3a post-corrosive esophageal stricture."3.88Risk Factors for Esophageal Stricture in Grade 2b and 3a Corrosive Esophageal Injuries. ( Awsakulsutthi, S; Boochangkool, N; Havanond, C; Kanlerd, A; Limpavitayaporn, P; Mahawongkajit, P; Mingmalairak, C; Tomtitchong, P, 2018)
"To review the literature on the treatment of gastroesophageal reflux disease (GERD) with emphasis on pharmacological aspects."2.43Treatment of gastroesophageal reflux disease. ( Camargos, PA; Guimarães, EV; Marguet, C, 2006)
"Peptic esophageal strictures are a common sequelae of long-standing reflux esophagitis."2.38Peptic strictures of the esophagus. ( Marks, RD; Richter, JE, 1993)
"Although the key features of eosinophilic esophagitis have been increasingly described over recent years, this entity is still often not considered and consequently diagnosis is often either not made or delayed."1.38Eosinophilic esophagitis and food impaction: an instructive case. ( Day, A; Lemberg, D; Tilakaratne, S, 2012)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."1.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)
"Cytology from Barrett's esophagus can be misleading in the presence of severe inflammation."1.30Brush cytology in the diagnosis of neoplasia in Barrett's esophagus. ( Alderson, D; Hardwick, RH; Lott, M; Morgan, RJ; Warren, BF, 1997)
"Only surgery improved regurgitation."1.30The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture. ( Gadenstaetter, M; Glaser, K; Hinder, RA; Profanter, C; Wetscher, GJ, 1999)
"Between 1965 and 1990 200 patients were treated for peptic esophageal stricture by surgery or bougienage with antisecretory medication."1.29Peptic esophageal stricture: is surgery still necessary? ( Bischof, G; Feil, W; Riegler, M; Schiessel, R; Wenzl, E, 1996)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's23 (57.50)18.2507
2000's13 (32.50)29.6817
2010's2 (5.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Mitchell, TK1
Hall, NJ1
Yardley, I1
Cole, C1
Hardy, P1
King, A1
Murray, D1
Nuthall, E1
Roehr, C1
Stanbury, K1
Williams, R1
Pearce, J1
Woolfall, K1
Mahawongkajit, P2
Tomtitchong, P2
Boochangkool, N2
Mingmalairak, C2
Awsakulsutthi, S2
Havanond, C2
Limpavitayaporn, P1
Kanlerd, A1
Vandenplas, Y1
Hauser, B1
Devreker, T1
Urbain, D1
Reynaert, H1
Tilakaratne, S1
Day, A1
Lemberg, D1
Ward, EM1
Achem, SR1
Nayyar, AK1
Royston, C1
Bardhan, KD1
Allakhverdian, AS1
Mazurin, VS1
Morozov, SV1
Isakov, VA1
Ibrahim, A1
Cole, RA1
Qureshi, WA1
Helaly, AZ1
Jamecci, A1
Graham, DY1
Ayub, K1
Panjehpour, M1
Overholt, BF1
Teraishi, F1
Fujiwara, T1
Jikuhara, A1
Kamitani, S1
Morino, Y1
Sato, K1
Tanaka, N1
Guimarães, EV1
Marguet, C1
Camargos, PA1
Sgouros, SN1
Vassiliadis, K1
Bergele, C1
Vlachogiannakos, J1
Stefanidis, G1
Mantides, A1
Garg, PK1
Sidhu, SS1
Bhargava, DK1
Cadiot, G1
Hélie, C1
Vallot, T1
Marmuse, JP1
Cosnes, J1
Riché, A1
Mignon, M1
Marks, RD2
Richter, JE2
Rizzo, J1
Koehler, RE1
Spenney, JG1
Mills, TP1
Champion, G1
Smith, PM1
Kerr, GD1
Cockel, R1
Ross, BA1
Bate, CM1
Brown, P1
Dronfield, MW1
Green, JR1
Hislop, WS1
Theodossi, A1
Foster, DR1
Jaspersen, D5
Körner, T2
Schorr, W3
Hammar, CH3
Blaurock, M1
Bischof, G1
Feil, W1
Riegler, M1
Wenzl, E1
Schiessel, R1
Swarbrick, ET1
Gough, AL1
Foster, CS1
Christian, J1
Garrett, AD1
Langworthy, CH1
Silvis, SE1
Farahmand, M1
Johnson, JA1
Ansel, HJ1
Ho, SB1
Lambert, R1
Schwacha, H1
Brennenstuhl, M1
Raschka, C1
Hardwick, RH1
Morgan, RJ1
Warren, BF1
Lott, M1
Alderson, D1
De Peppo, F1
Zaccara, A1
Dall'Oglio, L1
Federici di Abriola, G1
Ponticelli, A1
Marchetti, P1
Lucchetti, MC1
Rivosecchi, M1
Diehl, KL2
Schoeppner, H1
Geyer, P2
Martens, E2
Arps, H1
Borum, ML1
Marks, ZH1
Wetscher, GJ1
Glaser, K1
Gadenstaetter, M1
Profanter, C1
Hinder, RA1
Barbezat, GO1
Schlup, M1
Lubcke, R1
Yokohama, S1
Ishizeki, K1
Tamori, K1
Inaba, M1
Tani, M1
Makino, I1
Van Biervliet, S1
Van Winckel, M1
Robberecht, E1
Kerremans, I1
Chattopadhyay, A1
Singh, S1
Sood, A1
Wanchu, A1
Bambery, P1
Sheth, NP1
Carr, SJ1
Wicks, AC1
Lundell, L1
Koop, H1
Katschinski, M1
Arnold, R1

Reviews

5 reviews available for omeprazole and Esophageal Stricture

ArticleYear
Gastric heterotopia in the proximal esophagus complicated by stricture.
    Gastrointestinal endoscopy, 2003, Volume: 57, Issue:1

    Topics: Anti-Ulcer Agents; Choristoma; Dilatation; Esophageal Stenosis; Esophagoscopy; Humans; Male; Middle

2003
Treatment of gastroesophageal reflux disease.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Adult; Anti-Ulcer Agents; Barre

2006
Peptic strictures of the esophagus.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:8

    Topics: Behavior Therapy; Causality; Cimetidine; Diagnosis, Differential; Dilatation; Esophageal Stenosis; E

1993
Esophageal stricture from idiopathic ulcers in an AIDS patient: a case report and review of the literature.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Ulcer Agents; Biopsy; Endoscopy, Digestive System; E

1999
Acid suppression in the long-term treatment of peptic stricture and Barrett's oesophagus.
    Digestion, 1992, Volume: 51 Suppl 1

    Topics: Barrett Esophagus; Dilatation; Esophageal Stenosis; Gastric Acid; Gastric Acidity Determination; Gas

1992

Trials

12 trials available for omeprazole and Esophageal Stricture

ArticleYear
A prospective randomized controlled trial of omeprazole for preventing esophageal stricture in grade 2b and 3a corrosive esophageal injuries.
    Surgical endoscopy, 2021, Volume: 35, Issue:6

    Topics: Adult; Aftercare; Burns, Chemical; Caustics; Esophageal Stenosis; Humans; Omeprazole; Patient Discha

2021
[Antisecretory therapy for prevention of stenoses of bougienage after-burn of esophageal strictures].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2003, Issue:4

    Topics: Adult; Aged; Anti-Ulcer Agents; Burns, Chemical; Esophageal Stenosis; Esophagoscopy; Esophagus; Fema

2003
Schatzki's ring: to cut or break an unresolved problem.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Deglutition Disorders; Dilatation; Electrosurgery; En

2004
Single-session, graded esophageal dilation without fluoroscopy in outpatients with lower esophageal (Schatzki's) rings: a prospective, long-term follow-up study.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:5

    Topics: Aged; Ambulatory Care; Deglutition Disorders; Dilatation; Enzyme Inhibitors; Esophageal Stenosis; Es

2007
Role of omeprazole in prevention and treatment of postendoscopic variceal sclerotherapy esophageal complications. Double-blind randomized study.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Esophageal and Gastric Varices; Eso

1995
Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis.
    Gastroenterology, 1994, Volume: 106, Issue:4

    Topics: Aged; Cost-Benefit Analysis; Esophageal Stenosis; Esophagitis; Female; Histamine H2 Antagonists; Hum

1994
A comparison of omeprazole and ranitidine in the prevention of recurrence of benign esophageal stricture. Restore Investigator Group.
    Gastroenterology, 1994, Volume: 107, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Dilatation; Double-Blind Method; Esophageal

1994
Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dilatation; Double-Blind Method; Drug Ad

1996
A randomized blinded comparison of omeprazole and ranitidine in the treatment of chronic esophageal stricture secondary to acid peptic esophagitis.
    Gastrointestinal endoscopy, 1996, Volume: 43, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Chi-Square Distribution; Chronic Disease; Combined Modality Therapy; Dilata

1996
Omeprazole in the treatment of patients with complicated gastro-oesophageal reflux disease.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:10

    Topics: Antacids; Anti-Ulcer Agents; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Female; Follow-Up

1996
A comparison of omeprazole, lansoprazole and pantoprazole in the maintenance treatment of severe reflux oesophagitis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Deglutition

1998
Omeprazole therapy decreases the need for dilatation of peptic oesophageal strictures.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Dilatation; Enzyme Inhibitors; Esophageal Stenosi

1999

Other Studies

23 other studies available for omeprazole and Esophageal Stricture

ArticleYear
Mixed-methods feasibility study to inform a randomised controlled trial of proton pump inhibitors to reduce strictures following neonatal surgery for oesophageal atresia.
    BMJ open, 2023, 04-20, Volume: 13, Issue:4

    Topics: Adult; Attitude of Health Personnel; Chemoprevention; Constriction, Pathologic; Esophageal Atresia;

2023
Risk Factors for Esophageal Stricture in Grade 2b and 3a Corrosive Esophageal Injuries.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Body Height; Burns, Chemical; Caustics; Child; Endoscopy, Gastrointestinal; Esoph

2018
A biodegradable esophageal stent in the treatment of a corrosive esophageal stenosis in a child.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 49, Issue:2

    Topics: Absorbable Implants; Burns, Chemical; Caustics; Child; Esophageal Stenosis; Esophagitis; Esophagosco

2009
Eosinophilic esophagitis and food impaction: an instructive case.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2012, Volume: 23, Issue:3

    Topics: Adolescent; Androstadienes; Anti-Inflammatory Agents; Anti-Ulcer Agents; Deglutition Disorders; Drug

2012
Oesophageal acid-peptic strictures in the histamine H2 receptor antagonist and proton pump inhibitor era.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Catheterization; Esophageal Stenosis; Female; Gas

2003
Porfimer sodium photodynamic therapy for management of Barrett's esophagus with high-grade dysplasia.
    Lasers in surgery and medicine, 2006, Volume: 38, Issue:5

    Topics: Anti-Ulcer Agents; Barrett Esophagus; Catheter Ablation; Dihematoporphyrin Ether; Esophageal Neoplas

2006
Esophageal intramural pseudodiverticulosis with esophageal strictures successfully treated with dilation therapy.
    The Annals of thoracic surgery, 2006, Volume: 82, Issue:3

    Topics: Aged; Antifungal Agents; Candidiasis; Catheterization; Chronic Disease; Deglutition Disorders; Diagn

2006
[Stenosing esophagitis in Zollinger-Ellison syndrome].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:11

    Topics: Esophageal Stenosis; Esophagectomy; Esophagitis; Gastrectomy; Humans; Male; Middle Aged; Omeprazole;

1994
Strecker esophageal stent.
    Clinical radiology, 1994, Volume: 49, Issue:11

    Topics: Aged; Aged, 80 and over; Esophageal Stenosis; Female; Humans; Omeprazole; Stents

1994
[Bouginage of peptic esophageal stenoses. Results of one year with long-term omeprazole medication].
    Fortschritte der Medizin, 1994, Apr-10, Volume: 112, Issue:10

    Topics: Adult; Aged; Combined Modality Therapy; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Esopha

1994
[Omeprazole in H2-receptor blockader-refractory sclerosing ulcers of the esophagus].
    Deutsche medizinische Wochenschrift (1946), 1993, May-07, Volume: 118, Issue:18

    Topics: Esophageal and Gastric Varices; Esophageal Stenosis; Humans; Omeprazole; Polidocanol; Polyethylene G

1993
Peptic esophageal stricture: is surgery still necessary?
    Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Combined Modality Therapy

1996
Towards an increased efficacy of acid inhibition in the treatment of erosive oesophagitis.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:10

    Topics: Antacids; Anti-Ulcer Agents; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Histamine H2 Anta

1996
Brush cytology in the diagnosis of neoplasia in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1997, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cell Count; Cell Nucleus; Chromatin; C

1997
Stenting for caustic strictures: esophageal replacement replaced.
    Journal of pediatric surgery, 1998, Volume: 33, Issue:1

    Topics: Anti-Bacterial Agents; Burns, Chemical; Case-Control Studies; Catheterization; Child, Preschool; Dex

1998
[Benign proximal esophageal stenosis--mostly a complication of gastroesophageal reflux disease].
    Deutsche medizinische Wochenschrift (1946), 1999, Feb-26, Volume: 124, Issue:8

    Topics: Anti-Ulcer Agents; Diagnosis, Differential; Dilatation; Endoscopy, Digestive System; Esophageal Sten

1999
The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture.
    American journal of surgery, 1999, Volume: 177, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Cisapride;

1999
[Administration of proton pump inhibitor caused esophageal stenosis in two patients with severe reflux esophagitis].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2001, Volume: 98, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Drug Administration Schedule; Esophageal Stenosis; Es

2001
High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:9

    Topics: Digestive System Surgical Procedures; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagea

2001
Cervical osteophyte induced dysphagia.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: Anti-Ulcer Agents; Cervical Vertebrae; Cisapride; Deglutition Disorders; Esophageal Stenosis; Gastro

2001
High dose Omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2002, Volume: 37, Issue:6

    Topics: Esophageal Atresia; Esophageal Stenosis; Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole

2002
Omeprazole and oesophageal stricture.
    Lancet (London, England), 1992, Feb-01, Volume: 339, Issue:8788

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Dilatation; Esophageal Stenosis; Humans;

1992
[Conservative treatment of florid peptic esophageal stenosis. Complete elimination by dilatation and omeprazole in H2-blocker refractory cases].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Nov-15, Volume: 86, Issue:11

    Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Dilatation; Esophageal Stenosis; Esophagitis, Pe

1991