omeprazole has been researched along with Esophageal Neoplasms in 54 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (31.48) | 18.2507 |
| 2000's | 27 (50.00) | 29.6817 |
| 2010's | 6 (11.11) | 24.3611 |
| 2020's | 4 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Szachnowicz, S | 1 |
| Duarte, AF | 1 |
| Nasi, A | 1 |
| da Rocha, JRM | 1 |
| Seguro, FB | 1 |
| Bianchi, ET | 1 |
| Tustumi, F | 1 |
| de Moura, EGH | 1 |
| Sallum, RAA | 1 |
| Cecconello, I | 1 |
| Wronska, E | 1 |
| Polkowski, M | 1 |
| Orlowska, J | 1 |
| Mroz, A | 1 |
| Wieszczy, P | 1 |
| Regula, J | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 3 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 7 |
| Xue, L | 1 |
| Liu, L | 2 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 6 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Wang, Y | 3 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 4 |
| Chen, Y | 4 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
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| Liu, C | 3 |
| Lin, Y | 1 |
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| Wu, Y | 1 |
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| Yan, H | 2 |
| Ma, J | 1 |
| Fernández-Cuadros, ME | 1 |
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| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
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| Pérez-Moro, OS | 1 |
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| Wendel Garcia, PD | 1 |
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| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Argon Plasma Coagulation for Barrett's Esophagus With Low Grade Dysplasia: A Randomized Trial With Long Term Follow-up Evaluating the Impact of Power Setting and Proton Pump Inhibitor Dose[NCT04154748] | 71 participants (Actual) | Interventional | 2002-06-04 | Completed | |||
| Evaluating Efficacy and Safety of Combined Thread Embedding and Auricular Acupuncture in Gastroesophageal Reflux Disease With Liver Qi Invading Stomach Pattern: A Randomized Controlled Trial[NCT06157424] | 66 participants (Anticipated) | Interventional | 2023-12-06 | Recruiting | |||
| Evaluation of MicroRNA Expression in Blood and Cytology Specimens as a Novel Method for Detecting Barrett's Esophagus[NCT02464930] | 220 participants (Anticipated) | Observational | 2015-04-30 | Recruiting | |||
| Endoscopic Resection or Ablation for Patients With Dysplasia or Intramucosal Cancer in Barrett's Esophagus[NCT01572987] | 12 participants (Actual) | Interventional | 2011-09-30 | Terminated (stopped due to Recruitment goals not being met) | |||
| Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy for Screening of Barrett's Esophagus: A Prospective Tandem Study[NCT03167970] | 21 participants (Actual) | Observational | 2017-05-03 | Completed | |||
| A Phase II, Multi-Center Study of Interventional Spray Cryotherapy for Early-Stage Esophageal Cancer (ICE-CANCER)[NCT01868139] | 1 participants (Actual) | Interventional | 2013-06-30 | Terminated (stopped due to insufficient accrual) | |||
| Evaluating Gastro-oesophageal Reflux After Palliative Stenting for Malignant Distal Oesophageal Obstruction Using Anti-Reflux Stents: a Randomised Controlled Trial[NCT05303298] | 72 participants (Anticipated) | Interventional | 2022-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for omeprazole and Esophageal Neoplasms
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Gastroesophageal Reflux Disease: A Review.
Topics: Adenocarcinoma; Barrett Esophagus; Diagnosis, Differential; Esophageal Neoplasms; Fundoplication; Ga | 2020 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Clinical practice. Barrett's esophagus.
Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E | 2009 |
Does antireflux surgery prevent progression of Barrett's esophagus?
Topics: Adenocarcinoma; Barrett Esophagus; Cohort Studies; Combined Modality Therapy; Disease Progression; E | 2011 |
Do proton pump inhibitors protect against cancer progression in GERD?
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Barrett Esop | 2013 |
Reflux disease and Barrett's esophagus.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Endos | 2003 |
Review article: test and treat or treat and test in reflux disease?
Topics: Adenocarcinoma; Ambulatory Care; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neoplasms; Gastroe | 2003 |
[The clinical strategy for the Barrett's esophagus].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Ba | 2005 |
Review article: putting immediate-release proton-pump inhibitors into clinical practice--improving nocturnal acid control and avoiding the possible complications of excessive acid exposure.
Topics: Adenocarcinoma; Barrett Esophagus; Chronotherapy; Delayed-Action Preparations; Disease Progression; | 2005 |
High-grade dysplasia in Barrett's oesophagus. The case against oesophageal resection.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Endoscopy, Gastrointestinal; Esophageal Neoplasms; Esophagecto | 2007 |
[Surgical or conservative therapy of Barrett esophagus?].
Topics: Antacids; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Follow-Up Studies; Gastroesophageal Re | 1994 |
Barrett's esophagus: new definitions and approaches in children.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Barrett Esophagus; Child; Child, Preschool; Cimetidine; End | 1993 |
Gastro-oesophageal reflux and Helicobacter pylori.
Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Diagnosis, Differential; Esophageal Neoplasms; | 1998 |
[Conservative and surgical antireflux therapy as prevention of carcinoma].
Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Clinical Trials as Topic; Esophageal N | 2000 |
Management of GERD: medical versus surgical.
Topics: Adenocarcinoma; Anti-Ulcer Agents; Costs and Cost Analysis; Esophageal Neoplasms; Esophagitis, Pepti | 2001 |
Gastroesophageal reflux disease and Barrett's esophagus.
Topics: Adenocarcinoma; Barrett Esophagus; Endoscopy, Gastrointestinal; Esophageal Neoplasms; Esophagus; Gas | 2001 |
7 trials available for omeprazole and Esophageal Neoplasms
| Article | Year |
|---|---|
Argon plasma coagulation for Barrett's esophagus with low-grade dysplasia: a randomized trial with long-term follow-up on the impact of power setting and proton pump inhibitor dose.
Topics: Argon Plasma Coagulation; Barrett Esophagus; Esophageal Neoplasms; Follow-Up Studies; Humans; Omepra | 2021 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Long-term results of a randomized prospective study comparing medical and surgical treatment of Barrett's esophagus.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Anti-Ulcer Agents; Barrett Esophagus; Child; Esophageal Neo | 2003 |
Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett's high-grade dysplasia.
Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Combined Modality Therapy; Dihem | 2007 |
Randomised comparison of the FerX Ella antireflux stent and the ultraflex stent: proton pump inhibitor combination for prevention of post-stent reflux in patients with esophageal carcinoma involving the esophago-gastric junction.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drug-Eluting Stents; Esophageal Neoplasms | 2008 |
KTP laser destruction of dysplasia and early cancer in columnar-lined Barrett's esophagus.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neo | 1999 |
The economic impact of the diagnosis of dysplasia in Barrett's esophagus.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cost-Benefit Analysis; Esophageal Neoplasms; Esophagos | 2000 |
32 other studies available for omeprazole and Esophageal Neoplasms
| Article | Year |
|---|---|
Laparoscopic total fundoplication is superior to medical treatment for reducing the cancer risk in Barrett's esophagus: a long-term analysis.
Topics: Adenocarcinoma; Barrett Esophagus; Esophageal Neoplasms; Fundoplication; Humans; Laparoscopy; Omepra | 2022 |
Acid suppression medications reduce risk of oesophageal adenocarcinoma in Barrett's oesophagus: a nested case-control study in US male veterans.
Topics: Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Barrett Esophagus; Case-Contro | 2018 |
Omeprazole prevents CDX2 and SOX9 expression by inhibiting hedgehog signaling in Barrett's esophagus cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Barrett Esophagus; CDX2 Transcription Factor; Cell Line, Tumo | 2019 |
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
Topics: Acetylcysteine; Adenocarcinoma; alpha-Tocopherol; Animals; Disease Models, Animal; Esophageal Neopla | 2009 |
Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
Topics: Adenocarcinoma; Animals; Anti-Ulcer Agents; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibi | 2009 |
"War and Peace" with Barrett's esophagus.
Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Barrett Esophagus; Celeco | 2011 |
Refractory ulcer of reconstructed gastric tube after esophagectomy: a case report.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Carcinoma, Squamous Cell; Cy | 2013 |
Ablative mucosectomy is the procedure of choice to prevent Barrett's cancer.
Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Catheter Ablation; Esophageal Neoplasms; Esoph | 2003 |
Does chemoprevention of Barrett's esophagus using acid suppression and/or COX-2 inhibition prevent neoplastic progression?
Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 2002 |
[A case of the successful treatment of the esophageal leukoplakia with rabeprazole].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzimidazoles; Esophageal Neoplasms; Esophagitis, Pe | 2002 |
Mortality study of 18 000 patients treated with omeprazole.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cause of Death; Child; Duodenal Disea | 2003 |
Photodynamic therapy for Barrett's esophagus with dysplasia and/or early stage carcinoma: long-term results.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neo | 2003 |
Re: Cost-effectiveness of aspirin chemoprevention for Barrett's esophagus.
Topics: Adenocarcinoma; Adult; Aged; Anti-Ulcer Agents; Aspirin; Barrett Esophagus; Cost-Benefit Analysis; D | 2004 |
Continuous treatment of Barrett's oesophagus patients with proton pump inhibitors up to 13 years: observations on regression and cancer incidence.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Eso | 2006 |
Porfimer sodium photodynamic therapy for management of Barrett's esophagus with high-grade dysplasia.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Catheter Ablation; Dihematoporphyrin Ether; Esophageal Neoplas | 2006 |
Getting categorical on GERD.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Disease Progression; Esophageal Neoplasms; Esophagitis; Esopha | 2007 |
Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa, and treatment of superficial esophageal cancer.
Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antineoplastic Agents; Barrett Esophagus; Biopsy; Esophagea | 1995 |
[Partial regression of Barret esophagus with high grade dysplasia and adenocarcinoma after photocoagulation and endocurietherapy under antisecretory treatment].
Topics: Adenocarcinoma; Barrett Esophagus; Brachytherapy; Combined Modality Therapy; Endoscopy, Digestive Sy | 1995 |
[Leiomyomatosis of the esophagus].
Topics: Anti-Ulcer Agents; Biopsy; Cisapride; Combined Modality Therapy; Deglutition Disorders; Esophageal N | 1994 |
Esophageal adenocarcinoma associated with Barrett's esophagus: long-term management with laser ablation.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Barrett Esophagus; Endoscopy; Esophageal Neoplasms; Esophag | 1995 |
Photodynamic therapy for Barrett's esophagus: clinical update.
Topics: Adenocarcinoma; Adenoma, Villous; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Esophageal Neoplasms | 1996 |
Brush cytology in the diagnosis of neoplasia in Barrett's esophagus.
Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cell Count; Cell Nucleus; Chromatin; C | 1997 |
Rectal omeprazole in the treatment of reflux pain in esophageal cancer.
Topics: Administration, Rectal; Aged; Anti-Ulcer Agents; Esophageal Neoplasms; Female; Gastroesophageal Refl | 1998 |
Empirical therapy versus diagnostic tests in gastroesophageal reflux disease: a medical decision analysis.
Topics: Cost of Illness; Decision Support Techniques; Drug Therapy; Duodenal Ulcer; Enzyme Inhibitors; Esoph | 1998 |
Photodynamic therapy for Barrett's esophagus: follow-up in 100 patients.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antineoplastic Agents; Barrett Es | 1999 |
Laser and multipolar electrocoagulation ablation of early Barrett's adenocarcinoma: long-term follow-up.
Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Electrocoagulation; Esophageal Neoplasms | 1999 |
Gastric acid blockade with omeprazole promotes gastric carcinogenesis induced by duodenogastric reflux.
Topics: Adenocarcinoma; Animals; Anti-Ulcer Agents; Disease Models, Animal; Duodenogastric Reflux; Esophagea | 1999 |
Biomarker studies in reversed Barrett's esophagus.
Topics: Aged; Aged, 80 and over; Barrett Esophagus; Biomarkers, Tumor; Biopsy; Electrocoagulation; Epitheliu | 1999 |
Intramucosal adenocarcinoma arising under squamous re-epithelialisation of Barrett's oesophagus.
Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Humans; | 2000 |
[Award winning drug].
Topics: Antacids; Anti-Ulcer Agents; Esophageal Neoplasms; Gastric Acidity Determination; Gastroesophageal R | 1999 |
Long-term safety and efficacy of omeprazole in gastro-oesophageal reflux disease.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Drug Administration Schedule; Esophageal Neoplasms; Esophagiti | 2000 |
Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study.
Topics: Adenocarcinoma; Animals; Disease Models, Animal; Esophageal Neoplasms; Esophagostomy; Gastroesophage | 2001 |