Page last updated: 2024-11-01

omeprazole and Esophageal Diseases

omeprazole has been researched along with Esophageal Diseases in 45 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Esophageal Diseases: Pathological processes in the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"Esophageal candidiasis was diagnosed at endoscopy in two patients receiving omeprazole therapy."7.69Esophageal candidiasis following omeprazole therapy: a report of two cases. ( Chawla, LS; Jain, NP; Kumar, R; Sharma, M; Sood, A, 1995)
"Oesophageal candidiasis was diagnosed incidentally at endoscopy in two patients receiving omeprazole therapy."7.68Oesophageal candidiasis after omeprazole therapy. ( Larner, AJ; Lendrum, R, 1992)
"Such chronic ulcers have been associated with pain, stricture formation, and recurrent hemorrhage."5.28Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy. ( Gimson, A; Polson, R; Westaby, D; Williams, R, 1990)
" Adverse events that occurred significantly more often in the first month of treatment with esomeprazole compared with months 2-6 included diarrhoea, nausea/vomiting, abdominal pain, dyspepsia, headache/migraine, intolerance, malaise/lassitude, pruritus, unspecified adverse effects and abnormal sensation."3.74Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England. ( Davies, M; Shakir, SA; Wilton, LV, 2008)
"Esophageal candidiasis was diagnosed at endoscopy in two patients receiving omeprazole therapy."3.69Esophageal candidiasis following omeprazole therapy: a report of two cases. ( Chawla, LS; Jain, NP; Kumar, R; Sharma, M; Sood, A, 1995)
"Septicemia occurred in a long-term hemodialysis patient on oral iron supplementation who had been treated for esophageal ulcer by omeprazole, an ulcer-healing drug."3.68Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation. ( Fakir, M; Hardin, JM; Matta, B; Saison, C; Wong, T, 1992)
"Oesophageal candidiasis was diagnosed incidentally at endoscopy in two patients receiving omeprazole therapy."3.68Oesophageal candidiasis after omeprazole therapy. ( Larner, AJ; Lendrum, R, 1992)
"There were no recurrences of Schatzki's ring in the group of patients with documented GERD (follow-up [mean +/- SD]: 43."2.71Long-term acid suppressive therapy may prevent the relapse of lower esophageal (Schatzki's) rings: a prospective, randomized, placebo-controlled study. ( Avgerinos, A; Bergele, C; Karamanolis, G; Mantides, A; Papadopoulou, E; Sgouros, SN; Stefanidis, G; Vassiliadis, K; Vlachogiannakos, J, 2005)
"Lansoprazole has undergone extensive clinical evaluation for the treatment of acid-peptic diseases."2.40Safety profile of Lansoprazole: the US clinical trial experience. ( Freston, JW; Haber, M; Heller, CA; Jennings, D; Rose, PA, 1999)
"Severe gastroesophageal reflux disease is usually a chronic problem with periods of relapse, but effective medical and surgical therapies are available."2.39Severe gastroesophageal reflux disease. Medical and surgical options for long-term care. ( Marshall, JB, 1995)
"Although Boerhaave syndrome is generally considered to have poor prognosis, conservative therapy may be effective in select cases with early detection of the perforation."1.33Boerhaave syndrome treated conservatively following early endoscopic diagnosis: a case report. ( Katsuno, A; Makino, H; Matsuda, A; Matsutani, T; Miyashita, M; Nomura, T; Sasajima, K; Sasaki, J; Tajiri, T, 2006)
"Forty of 78 patients dying of oesophageal cancer had the disease present at registration."1.32Mortality study of 18 000 patients treated with omeprazole. ( Bateman, DN; Colin-Jones, D; Hartz, S; Langman, M; Logan, RF; Mant, J; Murphy, M; Paterson, KR; Rowsell, R; Thomas, S; Vessey, M, 2003)
"Such chronic ulcers have been associated with pain, stricture formation, and recurrent hemorrhage."1.28Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy. ( Gimson, A; Polson, R; Westaby, D; Williams, R, 1990)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.89)18.7374
1990's21 (46.67)18.2507
2000's17 (37.78)29.6817
2010's3 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levy, AN1
Ali, N1
Andrici, J1
Hamilton, MJ1
Roux, C1
Briot, K1
Gossec, L1
Kolta, S1
Blenk, T1
Felsenberg, D1
Reid, DM1
Eastell, R1
Glüer, CC1
di Palmo, E1
Cazzato, S1
Tursini, S1
Salfi, NC1
Mazzotta, A1
Di Silverio Carulli, C1
Lima, M1
Bergamaschi, R1
Bernardi, F1
Cicognani, A1
Cakal, B1
Akbal, E1
Köklü, S1
Babalı, A1
Koçak, E1
Taş, A1
Bateman, DN1
Colin-Jones, D1
Hartz, S1
Langman, M1
Logan, RF1
Mant, J1
Murphy, M1
Paterson, KR1
Rowsell, R1
Thomas, S1
Vessey, M1
Hong, SP1
Park, PW1
Hwang, SG1
Ko, KH1
Kwak, SY1
Kim, SH1
Kwon, KS1
Shin, YW1
Ryu, JK1
Ryu, KH1
Park, SJ1
Won, WH1
Yoo, HM1
Bae, HM1
Park, MJ1
Woo, YK1
Kim, KC1
Kim, KH1
Na, SH1
Kim, JW1
Akbulut, S1
Yavuz, B1
Köseoğlu, T1
Gököz, A1
Saritaş, U1
Farinati, F1
Cardin, R1
Russo, VM1
Busatto, G1
Franco, M1
Falda, A1
Mescoli, C1
Rugge, M1
Sgouros, SN1
Vlachogiannakos, J1
Karamanolis, G1
Vassiliadis, K1
Stefanidis, G1
Bergele, C1
Papadopoulou, E1
Avgerinos, A1
Mantides, A1
Alonso Fernández, M1
Silvers, WS1
Levine, JS1
Poole, JA1
Naar, E1
Weber, RW1
Cooper, BT1
Chapman, W1
Neumann, CS1
Gearty, JC1
Lancaster, JL1
Gosh, S1
Sethi, R1
Tripathi, S1
Matsuda, A1
Miyashita, M1
Sasajima, K1
Nomura, T1
Makino, H1
Matsutani, T1
Katsuno, A1
Sasaki, J1
Tajiri, T1
Okuyama, K1
Saito, N1
Kume, E1
Noto, T1
Nagasaki, M1
Davies, M1
Wilton, LV1
Shakir, SA1
Konda, A1
Cappell, MS1
Dieterle, L1
Haines, DE1
Garg, PK1
Sidhu, SS1
Bhargava, DK1
Bataller, R1
Bordas, JM1
Ordi, J1
Llach, J1
Elizalde, JI1
Mondelo, F1
Jaspersen, D1
Körner, T1
Schorr, W1
Hammar, CH1
Marshall, JB1
Sood, A1
Sharma, M1
Jain, NP1
Chawla, LS1
Kumar, R1
Rakic, S1
Pesko, P1
Dunjic, M1
Gerzic, Z1
Przemioslo, RT1
Mee, AS1
Lesur, G1
Paupard, T1
Turner, L1
Bergemer, AM1
Parlier, H1
Dupuy, P1
Mosimann, F1
González Carro, P1
Toro, H1
Balanzó, J1
Vilardell, F1
Kobayashi, S1
Kawabe, N1
Miyata, F1
Ito, H1
Kazumiya, H1
Murase, K1
Kurokawa, S1
Fujishima, K1
Freston, JW1
Rose, PA1
Heller, CA1
Haber, M1
Jennings, D1
Borum, ML1
Marks, ZH1
Cuddihy, PJ1
Maheshwar, A1
Griffith, H1
Martín de Argila, C1
Boixeda de Miquel, D1
Moreira Vicente, V1
García Plaza, A1
de Mestier, P1
Achem, SR1
DeVault, KR1
Reichart, M1
Busch, OR1
Bruno, MJ1
Van Lanschot, JJ1
Miehsler, W1
Püspök, A1
Oberhuber, T1
Vogelsang, H1
Johlin, FC1
Labrecque, DR1
Neil, GA1
Fakir, M1
Saison, C1
Wong, T1
Matta, B1
Hardin, JM1
Larner, AJ1
Lendrum, R1
Camara, DS1
Corasanti, JG1
Gimson, A1
Polson, R1
Westaby, D1
Williams, R1
Bory, M1
Dupin, B1
Hendel, L1
Svejgaard, E1
Walsøe, I1
Kieffer, M1
Stenderup, A1
Hameeteman, W1
Tytgat, GN1
Lee, FI1
Isaacs, PE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Non-cardiac Chest Pain Evaluation and Treatment Study (CARPA) - Part 2: Treatment Study[NCT00462241]115 participants (Actual)Interventional2006-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for omeprazole and Esophageal Diseases

ArticleYear
A rare association of inlet patch with laryngospasm: a report of two children and literature review.
    Pediatric pulmonology, 2011, Volume: 46, Issue:9

    Topics: Alginates; Anti-Ulcer Agents; Child; Child, Preschool; Esophageal Diseases; Female; Gastric Mucosa;

2011
Severe gastroesophageal reflux disease. Medical and surgical options for long-term care.
    Postgraduate medicine, 1995, Volume: 97, Issue:5

    Topics: Antacids; Anti-Ulcer Agents; Cisapride; Drug Therapy, Combination; Esophageal Diseases; Esophagogast

1995
Safety profile of Lansoprazole: the US clinical trial experience.
    Drug safety, 1999, Volume: 20, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Clinical Trials as Topic; Esophageal Dis

1999
Esophageal stricture from idiopathic ulcers in an AIDS patient: a case report and review of the literature.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Ulcer Agents; Biopsy; Endoscopy, Digestive System; E

1999
[Indications and use of omeprazole in esophago-gastro-duodenal diseases].
    Revista clinica espanola, 1999, Volume: 199, Issue:11

    Topics: Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Esophageal Diseases; Esophagitis; Gastritis;

1999
Recent developments in chest pain of undetermined origin.
    Current gastroenterology reports, 2000, Volume: 2, Issue:3

    Topics: Angina Pectoris; Anti-Ulcer Agents; Chest Pain; Diagnosis, Differential; Esophageal Diseases; Humans

2000
Update: gastroenterology and hepatology.
    Comprehensive therapy, 1991, Volume: 17, Issue:4

    Topics: Chronic Disease; Esophageal Diseases; Gastrointestinal Diseases; Humans; Interferons; Liver Diseases

1991

Trials

5 trials available for omeprazole and Esophageal Diseases

ArticleYear
Significance of non-erosive minimal esophageal lesions in gastro-esophageal reflux disorder.
    The Korean journal of internal medicine, 2004, Volume: 19, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

2004
Differential effects of Helicobacter pylori eradication on oxidative DNA damage at the gastroesophageal junction and at the gastric antrum.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:11 Pt 1

    Topics: Anti-Ulcer Agents; DNA Adducts; DNA Damage; Esophageal Diseases; Esophagogastric Junction; Female; G

2004
Long-term acid suppressive therapy may prevent the relapse of lower esophageal (Schatzki's) rings: a prospective, randomized, placebo-controlled study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:9

    Topics: Anti-Ulcer Agents; Dilatation; Esophageal Diseases; Female; Gastroesophageal Reflux; Humans; Hydroge

2005
Role of omeprazole in prevention and treatment of postendoscopic variceal sclerotherapy esophageal complications. Double-blind randomized study.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Esophageal and Gastric Varices; Eso

1995
Omeprazole in the management of sclerotherapy-induced esophageal ulcers resistant to H2 blocker treatment.
    Journal of gastroenterology, 1995, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Drug Resistance; Esophageal and Gastric Varices; Esophageal Diseases

1995

Other Studies

33 other studies available for omeprazole and Esophageal Diseases

ArticleYear
It's What's Up Front That Counts-Part Two: Esophageal Crohn's Disease Complicated by Recurrent Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Adalimumab; Anti-Bacterial Agents; Anti-Inflammatory Agents; Budesonide; Colonoscopy; Colostomy; Con

2019
Increase in vertebral fracture risk in postmenopausal women using omeprazole.
    Calcified tissue international, 2009, Volume: 84, Issue:1

    Topics: Aged; Anti-Ulcer Agents; Esophageal Diseases; Europe; Female; Humans; Menopause; Middle Aged; Omepra

2009
Acute therapy with intravenous omeprazole on caustic esophageal injury: a prospective case series.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2013, Volume: 26, Issue:1

    Topics: Adult; Burns, Chemical; Caustics; Cohort Studies; Emergency Treatment; Esophageal Diseases; Esophago

2013
Mortality study of 18 000 patients treated with omeprazole.
    Gut, 2003, Volume: 52, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cause of Death; Child; Duodenal Disea

2003
Crohn's disease with isolated esophagus and gastric involvement.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2004, Volume: 15, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Azathioprine; Biopsy; Crohn Disease; Endoscopy, Gastrointestinal; Esophage

2004
[Oesophageal ulcer and doxycycline].
    Atencion primaria, 2005, Sep-15, Volume: 36, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Doxycycline; Drug Therapy, Combination; Esophageal Disease

2005
Inlet patch of gastric mucosa in upper esophagus causing chronic cough and vocal cord dysfunction.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Androstadienes; Anti-Allergic Agents; Cough; Endoscopy, Gas

2006
Continuous treatment of Barrett's oesophagus patients with proton pump inhibitors up to 13 years: observations on regression and cancer incidence.
    Alimentary pharmacology & therapeutics, 2006, Mar-15, Volume: 23, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Eso

2006
Can heterotopic gastric mucosa present as globus pharyngeus?
    The Journal of laryngology and otology, 2006, Volume: 120, Issue:7

    Topics: Anti-Ulcer Agents; Choristoma; Conversion Disorder; Diagnosis, Differential; Esophageal Diseases; Fe

2006
Boerhaave syndrome treated conservatively following early endoscopic diagnosis: a case report.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2006, Volume: 73, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Chest Pain; Combined Modality Therapy; Endoscopy, Gastrointestinal; En

2006
Ecabet sodium prevents esophageal lesions induced by the reflux of gastric juice in rats.
    Inflammopharmacology, 2007, Volume: 15, Issue:2

    Topics: Abietanes; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Drug Synergism; Drug Therap

2007
Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England.
    Drug safety, 2008, Volume: 31, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Cohort Studies; Diarrhea; Drug Monitoring; Dyspepsia; Engla

2008
Esophageal ulceration from high-intensity focused US catheter ablation for pulmonary vein isolation: a novel complication in the treatment of symptomatic refractory atrial fibrillation.
    Gastrointestinal endoscopy, 2008, Volume: 68, Issue:3

    Topics: Atrial Fibrillation; Catheter Ablation; Drug Therapy, Combination; Esophageal Diseases; Esophagoscop

2008
Upper gastrointestinal bleeding: a complication of "inlet patch mucosa" in the upper esophagus.
    Endoscopy, 1995, Volume: 27, Issue:3

    Topics: Adult; Biopsy, Needle; Endoscopy, Digestive System; Esophageal Diseases; Gastric Mucosa; Gastrointes

1995
Esophageal candidiasis following omeprazole therapy: a report of two cases.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1995, Volume: 14, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Candidiasis; Esophageal Diseases; Female; Gastritis; Humans; Keto

1995
Acid-suppression did not enhance healing of gastric ulcer associated with paraesophageal hernia after hernial reduction.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:1

    Topics: Esophageal Diseases; Gastric Acid; Hernia; Herniorrhaphy; Humans; Male; Middle Aged; Omeprazole; Ran

1995
Omeprazole in possible esophageal Crohn's disease.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:7

    Topics: Adolescent; Crohn Disease; Esophageal Diseases; Humans; Male; Omeprazole

1994
[Esophageal mycosis during treatment with omeprazole].
    Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:8-9

    Topics: Esophageal Diseases; Fluconazole; Humans; Male; Middle Aged; Mycoses; Omeprazole; Stomach Ulcer

1993
Esophageal candidiasis, omeprazole therapy, and organ transplantation--a word of caution.
    Transplantation, 1993, Volume: 56, Issue:2

    Topics: Candidiasis; Esophageal Diseases; Humans; Liver Transplantation; Omeprazole; Opportunistic Infection

1993
[Esophageal candidiasis during omeprazole treatment].
    Medicina clinica, 1993, Apr-24, Volume: 100, Issue:16

    Topics: Aged; Aged, 80 and over; Candidiasis; Esophageal Diseases; Humans; Male; Omeprazole; Peptic Ulcer He

1993
[A case of Behcet's syndrome associated with esophageal ulcer].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, Dec-10, Volume: 87, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents; Anti-Ulcer Agents; Behcet

1998
Symptomatic heterotopic gastric mucosa in the upper oesophagus.
    The Journal of laryngology and otology, 1998, Volume: 112, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Choristoma; Cimetidine; Esophageal Disea

1998
[Congress of the American College of Surgeons (ACS). San Francisco, 10-15 October 1999].
    Journal de chirurgie, 1999, Volume: 136, Issue:6

    Topics: Anti-Ulcer Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholang

1999
Black esophagus: a view in the dark.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2000, Volume: 13, Issue:4

    Topics: Acute Disease; Aged; Anti-Ulcer Agents; Esophageal Diseases; Esophagus; Gastric Outlet Obstruction;

2000
Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tract.
    Inflammatory bowel diseases, 2001, Volume: 7, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Crohn Disease; Data Interpretatio

2001
Omeprazole heals mucosal ulcers associated with endoscopic injection sclerotherapy.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:9

    Topics: Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Esophageal Diseases; Female; Humans; Male; M

1992
Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 19, Issue:3

    Topics: Aged; Anemia, Hypochromic; Bacteremia; Esophageal Diseases; Female; Ferrous Compounds; Humans; Omepr

1992
Oesophageal candidiasis after omeprazole therapy.
    Gut, 1992, Volume: 33, Issue:6

    Topics: Aged; Candidiasis; Esophageal Diseases; Gastric Acid; Humans; Male; Middle Aged; Omeprazole; Stomach

1992
Omeprazole in the management of intractable esophageal ulceration following injection sclerotherapy.
    Gastroenterology, 1990, Volume: 99, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Esophageal Diseases; Follow-Up Studies; Humans; Injections; Middle A

1990
[Angina-like chest pain of esophageal origin].
    Presse medicale (Paris, France : 1983), 1989, Dec-02, Volume: 18, Issue:40

    Topics: Catheterization; Chest Pain; Esophageal Diseases; Humans; Hydrochloric Acid; Hydrogen-Ion Concentrat

1989
Esophageal candidosis in progressive systemic sclerosis: occurrence, significance, and treatment with fluconazole.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:10

    Topics: Adult; Aged; Antifungal Agents; Candidiasis; Esophageal Diseases; Esophagoscopy; Female; Fluconazole

1988
Healing of chronic Barrett ulcers with omeprazole.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:9

    Topics: Aged; Anti-Ulcer Agents; Barrett Esophagus; Benzimidazoles; Drug Resistance; Esophageal Diseases; Es

1986
Barrett's ulcer: response to standard dose ranitidine, high dose ranitidine, and omeprazole.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:9

    Topics: Barrett Esophagus; Drug Administration Schedule; Drug Therapy, Combination; Esophageal Diseases; Eso

1988