Page last updated: 2024-11-01

omeprazole and Equine Diseases

omeprazole has been researched along with Equine Diseases in 53 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Equine gastric ulcer syndrome (EGUS) is the most common disease of the stomach in horses and treatment is based on the oral administration of omeprazole for at least 28 days."9.69A Comparison of the Efficacy of Two Omeprazole Formulations in the Treatment of Equine Gastric Ulcer Syndrome in Racehorses: A Blinded, Randomized Clinical Trial. ( Busechian, S; Conte, G; Conti, MB; Marchesi, MC; Pieramati, C; Rueca, F; Sgorbini, M; Vitale, V; Zappulla, F, 2023)
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."9.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
"To test the hypothesis that aloe vera would be noninferior to omeprazole in the treatment of equine gastric ulcer syndrome."9.27Comparison of aloe vera and omeprazole in the treatment of equine gastric ulcer syndrome. ( Bush, J; Franklin, S; van den Boom, R, 2018)
"To further investigate the presence of a dose relationship in the treatment of gastric ulceration under conditions that may favour omeprazole efficacy such as administration prior to exercise and after a brief fast, and potential differences between the response of squamous and glandular ulceration to omeprazole therapy."9.20A comparison of three doses of omeprazole in the treatment of equine gastric ulcer syndrome: A blinded, randomised, dose-response clinical trial. ( Hallowell, GD; Sykes, BW; Sykes, KM, 2015)
"To compare: 1) the efficacy of 2 doses of omeprazole in the treatment of primary squamous and glandular gastric ulceration; and 2) the healing response of primary squamous and glandular gastric ulceration to acid suppression therapy."9.19A comparison of two doses of omeprazole in the treatment of equine gastric ulcer syndrome: a blinded, randomised, clinical trial. ( Hallowell, GD; Sykes, BW; Sykes, KM, 2014)
"To determine the effects of 8 days of light to heavy exercise on gastric ulcer development in horses and determine the efficacy of omeprazole paste in preventing gastric ulceration."9.12Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration. ( Cramer, LG; Fleishman, C; Holste, JE; McClure, SR; Murray, MJ; Sifferman, R; White, G, 2007)
"Omeprazole oral paste administered at a dosage of 1 mg/kg, PO, every 24 hours for 28 days was effective for prevention of recurrence of gastric ulcers in horses in race training."9.11Efficacy of omeprazole paste for prevention of recurrence of gastric ulcers in horses in race training. ( Alva, R; Bernard, W; Cramer, LG; Fleishman, C; Holste, JE; Hughes, FE; McClure, SR; Sifferman, RL; White, GW, 2005)
"Results suggest that although administration of the commercially available paste omeprazole formulation was effective in promoting healing of gastric ulcers in these horses, administration of the compounded omeprazole suspension was ineffective."9.10Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training. ( Aleman, MR; Nieto, JE; Pipers, FS; Smith, DC; Snyder, JR; Spier, S; Stanley, S, 2002)
"A multicentre, blinded, randomised complete-block, field trial was conducted with 140 horses and foals age 4 weeks-28 years to determine if omeprazole paste is effective and safe in promoting healing of spontaneous gastric ulcers under a variety of field conditions and in different breeds and ages of horses."9.09Effects of omeprazole paste on healing of spontaneous gastric ulcers in horses and foals: a field trial. ( Cox, JL; Ericcson, GF; Holste, JE; MacAllister, CG; McClure, SR; Sifferman, RL; Vatistas, NJ; White, GW, 1999)
"Seventeen Thoroughbred horses with moderate to severe gastric ulceration were purchased from a race track within 10 days of racing and were treated once daily with either omeprazole (9 horses) or vehicle (8 horses) and evaluated gastroscopically for ulcer healing."9.08Effects of omeprazole on healing of naturally-occurring gastric ulcers in thoroughbred racehorses. ( Eagleson, J; Eichorn, ES; Haven, ML; Hickey, GJ; Murray, MJ; Zhang, D, 1997)
"In preventing gastric ulcer occurrence, omeprazole prophylaxis was superior to sham in training horses (7 trials, 566 horses, RR 0."9.01Prophylactic therapy with omeprazole for prevention of equine gastric ulcer syndrome (EGUS) in horses in active training: A meta-analysis. ( Mason, LV; Mason, RJ; Moroney, JR, 2019)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."7.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
"Following induction of gastric ulcers by intermittent feed deprivation, horses underwent sucrose permeability testing (administration of sucrose by nasogastric intubation followed by collection of urine at 2 and 4 hours after intubation) and gastric endoscopy."7.72Evaluation of urine sucrose concentration for detection of gastric ulcers in horses. ( Cohen, ND; Meddings, JB; O'Conner, MS; Pipers, F; Roussel, AJ; Steiner, JM; Williams, DA, 2004)
"The efficacy of a paste formulation of the H+, K+, -ATPase inhibitor omeprazole was evaluated in standardbred racehorses for the treatment and prevention of gastric ulcers."7.72Efficacy of a paste formulation of omeprazole for the treatment of naturally occurring gastric ulcers in training standardbred racehorses in Canada. ( Alva, R; Dionne, R; Doucet, MY; Ericsson, G; Vrins, AA, 2003)
"To compare pharmacokinetic and pharmacodynamic effects of a novel omeprazole formulation against a currently registered product."6.84Pharmacokinetic and pharmacodynamic effects of two omeprazole formulations on stomach pH and gastric ulcer scores. ( Andrews, FM; Nielsen, SG; Raidal, SL; Trope, G, 2017)
"To determine the minimal effective dosage of omeprazole oral paste for the prevention of naturally occurring ulcers in horses starting race training."6.71Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training. ( Alva, R; Bernard, W; Cramer, LG; Doucet, MY; Fleishman, C; Holste, JE; McClure, SR; Sifferman, RL; Vrins, A; White, GW, 2005)
" The results of this study suggest that omeprazole, employing a once daily dosing schedule, is effective at reducing the severity or eliminating gastric ulcers in Thoroughbreds in active race training."6.69Acceptability of a paste formulation and efficacy of high dose omeprazole in healing gastric ulcers in horses maintained in race training. ( Holste, J; Nieto, J; Pollmeier, M; Snyder, JR; Thompson, D; Vatistas, NJ, 1999)
" At Day 28, 25 of treated horses continued on this dosing regimen while 25 received a half dose (2 mg/kg bwt once daily) and 25 horses were sham-dosed."6.69Efficacy of omeprazole paste in the treatment and prevention of gastric ulcers in horses. ( Alva, R; Andrews, FM; Bernard, W; Cox, JL; Daurio, CP; Holste, JE; Hughes, FE; Sifferman, RL, 1999)
"Equine gastric ulcer syndrome (EGUS) is the most common disease of the stomach in horses and treatment is based on the oral administration of omeprazole for at least 28 days."5.69A Comparison of the Efficacy of Two Omeprazole Formulations in the Treatment of Equine Gastric Ulcer Syndrome in Racehorses: A Blinded, Randomized Clinical Trial. ( Busechian, S; Conte, G; Conti, MB; Marchesi, MC; Pieramati, C; Rueca, F; Sgorbini, M; Vitale, V; Zappulla, F, 2023)
"This study was performed 1) to investigate the prevalence and the severity of gastric ulcers in Thoroughbred racehorses in Korea, 2) to confirm the therapeutic effect of ranitidine and omeprazole, and 3) to compare the efficacy between ranitidine and omeprazole."5.51Prevalence and treatment of gastric ulcers in Thoroughbred racehorses of Korea. ( Cho, S; Dong, HJ; Han, J; Hwang, H; Kim, Y; Lee, I, 2022)
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."5.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
"To test the hypothesis that aloe vera would be noninferior to omeprazole in the treatment of equine gastric ulcer syndrome."5.27Comparison of aloe vera and omeprazole in the treatment of equine gastric ulcer syndrome. ( Bush, J; Franklin, S; van den Boom, R, 2018)
"To further investigate the presence of a dose relationship in the treatment of gastric ulceration under conditions that may favour omeprazole efficacy such as administration prior to exercise and after a brief fast, and potential differences between the response of squamous and glandular ulceration to omeprazole therapy."5.20A comparison of three doses of omeprazole in the treatment of equine gastric ulcer syndrome: A blinded, randomised, dose-response clinical trial. ( Hallowell, GD; Sykes, BW; Sykes, KM, 2015)
"To compare: 1) the efficacy of 2 doses of omeprazole in the treatment of primary squamous and glandular gastric ulceration; and 2) the healing response of primary squamous and glandular gastric ulceration to acid suppression therapy."5.19A comparison of two doses of omeprazole in the treatment of equine gastric ulcer syndrome: a blinded, randomised, clinical trial. ( Hallowell, GD; Sykes, BW; Sykes, KM, 2014)
"To determine the effects of 8 days of light to heavy exercise on gastric ulcer development in horses and determine the efficacy of omeprazole paste in preventing gastric ulceration."5.12Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration. ( Cramer, LG; Fleishman, C; Holste, JE; McClure, SR; Murray, MJ; Sifferman, R; White, G, 2007)
"Omeprazole oral paste administered at a dosage of 1 mg/kg, PO, every 24 hours for 28 days was effective for prevention of recurrence of gastric ulcers in horses in race training."5.11Efficacy of omeprazole paste for prevention of recurrence of gastric ulcers in horses in race training. ( Alva, R; Bernard, W; Cramer, LG; Fleishman, C; Holste, JE; Hughes, FE; McClure, SR; Sifferman, RL; White, GW, 2005)
"Results suggest that although administration of the commercially available paste omeprazole formulation was effective in promoting healing of gastric ulcers in these horses, administration of the compounded omeprazole suspension was ineffective."5.10Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training. ( Aleman, MR; Nieto, JE; Pipers, FS; Smith, DC; Snyder, JR; Spier, S; Stanley, S, 2002)
"Omeprazole has been shown to promote healing of spontaneously occurring gastric ulcers in horses when administered for 28 days at a dose of 4 mg/kg bwt/day and to prevent recurrence of ulcers in almost all horses when treatment is continued at a dose of at least 2 mg/kg bwt/day."5.09Safety of omeprazole paste in foals and mature horses. ( Attebery, DK; Cox, JL; Daurio, C; Plue, RE; Wall, HG; Wallace, DH, 1999)
"A multicentre, blinded, randomised complete-block, field trial was conducted with 140 horses and foals age 4 weeks-28 years to determine if omeprazole paste is effective and safe in promoting healing of spontaneous gastric ulcers under a variety of field conditions and in different breeds and ages of horses."5.09Effects of omeprazole paste on healing of spontaneous gastric ulcers in horses and foals: a field trial. ( Cox, JL; Ericcson, GF; Holste, JE; MacAllister, CG; McClure, SR; Sifferman, RL; Vatistas, NJ; White, GW, 1999)
"Seventeen Thoroughbred horses with moderate to severe gastric ulceration were purchased from a race track within 10 days of racing and were treated once daily with either omeprazole (9 horses) or vehicle (8 horses) and evaluated gastroscopically for ulcer healing."5.08Effects of omeprazole on healing of naturally-occurring gastric ulcers in thoroughbred racehorses. ( Eagleson, J; Eichorn, ES; Haven, ML; Hickey, GJ; Murray, MJ; Zhang, D, 1997)
"In preventing gastric ulcer occurrence, omeprazole prophylaxis was superior to sham in training horses (7 trials, 566 horses, RR 0."5.01Prophylactic therapy with omeprazole for prevention of equine gastric ulcer syndrome (EGUS) in horses in active training: A meta-analysis. ( Mason, LV; Mason, RJ; Moroney, JR, 2019)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."3.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
" Beginning on day 14, horses were administered omeprazole (4 mg/kg, PO, q 24 h until day 56) or no drug (10 horses/group) and underwent alternating 24-hour periods of feeding and feed withholding for 10 days to induce gastric ulceration."3.75Effect of gastric ulceration on physiologic responses to exercise in horses. ( Jones, JH; Nieto, JE; Snyder, JR; Vatistas, NJ, 2009)
"Results suggest that the proprietary formulation of omeprazole was associated with a significantly lower risk of moderate or severe gastric ulceration, compared with no treatment, in racehorses in active race training, whereas other antiulcer medications were not."3.72Odds of moderate or severe gastric ulceration in racehorses receiving antiulcer medications. ( Haddock, M; Orsini, JA; Rabuffo, TS; Smith, G; Stine, L; Sullivan, EK, 2003)
"Following induction of gastric ulcers by intermittent feed deprivation, horses underwent sucrose permeability testing (administration of sucrose by nasogastric intubation followed by collection of urine at 2 and 4 hours after intubation) and gastric endoscopy."3.72Evaluation of urine sucrose concentration for detection of gastric ulcers in horses. ( Cohen, ND; Meddings, JB; O'Conner, MS; Pipers, F; Roussel, AJ; Steiner, JM; Williams, DA, 2004)
"The efficacy of a paste formulation of the H+, K+, -ATPase inhibitor omeprazole was evaluated in standardbred racehorses for the treatment and prevention of gastric ulcers."3.72Efficacy of a paste formulation of omeprazole for the treatment of naturally occurring gastric ulcers in training standardbred racehorses in Canada. ( Alva, R; Dionne, R; Doucet, MY; Ericsson, G; Vrins, AA, 2003)
"Gastric ulcers were induced through intermittent feed withholding on days 21 to 28."3.30Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses. ( Berryhill, EH; Finno, CJ; Knych, H; Louie, EW; Morgan, JM; Nieto, J; Wensley, F, 2023)
"A prospective, blinded randomized interventional study was trial, conducted in 3 parts: (a) bioavailability study, (b) dose titration study, and (c) comparative clinical pharmacodynamic study, each using a blocked crossover design."3.01Pharmacokinetic and pharmacodynamic effects of 2 registered omeprazole preparations and varying dose rates in horses. ( Edwards, S; Hughes, KJ; Jacobson, GA; Narkowicz, CK; Raidal, SL; Wise, JC, 2021)
"Misoprostol was shown to be superior to combined omeprazole-sucralfate both for healing (M - 72% [95% CI 43-67] and OS - 20% [95% CI 7-41]; P<0."2.90Misoprostol is superior to combined omeprazole-sucralfate for the treatment of equine gastric glandular disease. ( Bowen, IM; Habershon-Butcher, JL; Hallowell, GD; Nicholls, V; Varley, G, 2019)
"To compare pharmacokinetic and pharmacodynamic effects of a novel omeprazole formulation against a currently registered product."2.84Pharmacokinetic and pharmacodynamic effects of two omeprazole formulations on stomach pH and gastric ulcer scores. ( Andrews, FM; Nielsen, SG; Raidal, SL; Trope, G, 2017)
"To determine the minimal effective dosage of omeprazole oral paste for the prevention of naturally occurring ulcers in horses starting race training."2.71Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training. ( Alva, R; Bernard, W; Cramer, LG; Doucet, MY; Fleishman, C; Holste, JE; McClure, SR; Sifferman, RL; Vrins, A; White, GW, 2005)
"Omeprazole was more effective than ranitidine in healing gastric squamous ulcers in Thoroughbreds in race training."2.71Effects of treatment with omeprazole or ranitidine on gastric squamous ulceration in racing Thoroughbreds. ( Lester, GD; Robertson, ID; Smith, RL, 2005)
" At Day 28, 25 of treated horses continued on this dosing regimen while 25 received a half dose (2 mg/kg bwt once daily) and 25 horses were sham-dosed."2.69Efficacy of omeprazole paste in the treatment and prevention of gastric ulcers in horses. ( Alva, R; Andrews, FM; Bernard, W; Cox, JL; Daurio, CP; Holste, JE; Hughes, FE; Sifferman, RL, 1999)
" The results of this study suggest that omeprazole, employing a once daily dosing schedule, is effective at reducing the severity or eliminating gastric ulcers in Thoroughbreds in active race training."2.69Acceptability of a paste formulation and efficacy of high dose omeprazole in healing gastric ulcers in horses maintained in race training. ( Holste, J; Nieto, J; Pollmeier, M; Snyder, JR; Thompson, D; Vatistas, NJ, 1999)
" The oral administration of omeprazole has been shown to be effective in both treating horses with gastric ulceration and at preventing re-occurrence whilst the horses are in training, provided that daily dosing is maintained."2.44Equine gastric ulcer syndrome in adult horses: a review. ( Bell, RJ; Kingston, JK; Mogg, TD, 2007)
" Therefore, the use of singular dosing recommendations that encompass all horse types and management conditions may not be appropriate and dosing recommendations that take into account the diet of the horse may be advantageous."1.46The effects of dose and diet on the pharmacodynamics of omeprazole in the horse. ( Greer, R; McGowan, CM; Mills, PC; Sykes, BW; Underwood, C, 2017)
"Optimal timing for daily dosing of athletic horses with an effective OME preparation, in order to suppress gastric squamous ulceration, might be 4-8 h prior to a training session."1.32Effect of GastroGard and three compounded oral omeprazole preparations on 24 h intragastric pH in gastrically cannulated mature horses. ( Burrow, JA; Church, M; Ludzia, S; Merritt, AM; Sanchez, LC, 2003)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (15.09)18.2507
2000's16 (30.19)29.6817
2010's18 (33.96)24.3611
2020's11 (20.75)2.80

Authors

AuthorsStudies
Meinke, PT1
Gough, S2
Hallowell, G2
Rendle, D3
Hwang, H1
Dong, HJ1
Han, J1
Cho, S1
Kim, Y1
Lee, I1
Pratt, SL2
Bowen, M2
Hallowell, GH2
Shipman, E2
Bailey, J2
Redpath, A2
Louie, EW2
Berryhill, EH2
Nieto, J3
Wensley, F2
Knych, H2
Finno, CJ2
Morgan, JM2
Sundra, T1
Kelty, E1
Busechian, S1
Conti, MB1
Sgorbini, M1
Conte, G1
Marchesi, MC1
Pieramati, C1
Zappulla, F1
Vitale, V1
Rueca, F1
Luthersson, N1
Bolger, C1
Fores, P1
Barfoot, C1
Nelson, S1
Parkin, T1
Harris, P1
Pagan, JD1
Petroski-Rose, L1
Mann, A1
Hauss, A1
Ricord, M1
Andrews, FM5
Yñiguez, FJM1
Keowen, M1
Garza, F1
Paul, L1
Chapman, A1
Banse, HE1
Cerri, S1
Taminiau, B1
de Lusancay, AH1
Lecoq, L1
Amory, H1
Daube, G1
Cesarini, C1
Wise, JC1
Hughes, KJ1
Edwards, S1
Jacobson, GA1
Narkowicz, CK1
Raidal, SL2
Zavoshti, FR1
Sykes, BW6
Kathawala, K1
Song, Y1
Garg, S1
Page, SW1
Underwood, C2
Mills, PC2
Nielsen, SG1
Trope, G1
Bush, J1
van den Boom, R1
Franklin, S1
Huxford, KE1
Dart, AJ1
Perkins, NR1
Bell, R1
Jeffcott, LB1
Mason, LV1
Moroney, JR1
Mason, RJ1
Varley, G1
Bowen, IM1
Habershon-Butcher, JL1
Nicholls, V1
Hallowell, GD5
Sykes, KM3
Sykes, K1
Alwan, W1
Banerjee, P1
White, IR1
Al-Falah, K1
Schachter, J1
Sasseville, D1
Greer, R1
McGowan, CM1
Nieto, JE4
Snyder, JR4
Vatistas, NJ4
Jones, JH1
Aleman, M1
Higgins, JK1
Endo, Y1
Tsuchiya, T1
Sato, F1
Murase, H1
Omura, T1
Korosue, K1
Nambo, Y1
Ishimaru, M1
Wakui, Y1
Furr, M1
Cohen, ND2
Axon, JE1
Sanchez, LC3
Pantaleon, L1
Haggett, E1
Campbell, R1
Tennent-Brown, B1
Spier, S1
Pipers, FS1
Stanley, S1
Aleman, MR1
Smith, DC1
Doucet, MY2
Vrins, AA1
Dionne, R1
Alva, R4
Ericsson, G1
Orsini, JA1
Haddock, M1
Stine, L1
Sullivan, EK1
Rabuffo, TS1
Smith, G1
Merritt, AM1
Burrow, JA1
Church, M1
Ludzia, S1
O'Conner, MS1
Steiner, JM1
Roussel, AJ1
Williams, DA1
Meddings, JB1
Pipers, F1
McClure, SR4
White, GW3
Sifferman, RL4
Bernard, W3
Vrins, A1
Holste, JE5
Fleishman, C3
Cramer, LG3
Hughes, FE2
Lester, GD1
Smith, RL1
Robertson, ID1
Stämpfli, H1
Oliver, OE1
Graves, EA1
Bell, RJ1
Mogg, TD1
Kingston, JK1
White, G1
Sifferman, R1
Murray, MJ3
Javsicas, LH1
Haven, ML1
Eichorn, ES1
Zhang, D1
Eagleson, J1
Hickey, GJ1
Doherty, TJ1
Blackford, JT1
Nadeau, JA1
Saxton, AM1
Plue, RE1
Wall, HG1
Daurio, C1
Attebery, DK1
Cox, JL3
Wallace, DH1
Thompson, D2
Pollmeier, M1
Holste, J1
MacAllister, CG1
Ericcson, GF1
Daurio, CP1
van den Wollenberg, L1
Sloet van Oldruitenborgh-Oosterbaan, MM1

Reviews

6 reviews available for omeprazole and Equine Diseases

ArticleYear
Perspectives in animal health: old targets and new opportunities.
    Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anti-Ulcer Age

2001
Therapeutics for Equine Gastric Ulcer Syndrome.
    The Veterinary clinics of North America. Equine practice, 2017, Volume: 33, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Horse Diseases; Horses; Omeprazole; Proton Pump Inhibitors; Stomach Ulce

2017
Prophylactic therapy with omeprazole for prevention of equine gastric ulcer syndrome (EGUS) in horses in active training: A meta-analysis.
    Equine veterinary journal, 2019, Volume: 51, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Bias; Confidence Intervals; Female; Horse Diseases; Horses; Male; Odds R

2019
Equine gastric ulcer syndrome in adult horses: a review.
    New Zealand veterinary journal, 2007, Volume: 55, Issue:1

    Topics: Animal Husbandry; Animals; Anti-Ulcer Agents; Gastric Mucosa; Horse Diseases; Horses; Omeprazole; Ph

2007
Suppression of gastric acidity in horses.
    Journal of the American Veterinary Medical Association, 1997, Jul-01, Volume: 211, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Horse Diseases;

1997
[Gastric ulceration in horses: etiology, diagnosis, and therapy: a review].
    Tijdschrift voor diergeneeskunde, 2000, Nov-01, Volume: 125, Issue:21

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Antacids; Anti-Ulcer Agents; Dose-Response Relatio

2000

Trials

25 trials available for omeprazole and Equine Diseases

ArticleYear
Prevalence and treatment of gastric ulcers in Thoroughbred racehorses of Korea.
    Journal of veterinary science, 2022, Volume: 23, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Horse Diseases; Horses; Omeprazole; Prevalence; Stomach Ulcer

2022
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
Changes in Heart Rate Variability with Induction of Gastric Ulcers in Adult Horses.
    Journal of equine veterinary science, 2023, Volume: 121

    Topics: Animals; Anti-Ulcer Agents; Heart Rate; Horse Diseases; Horses; Omeprazole; Stomach Ulcer; Ulcer

2023
A Comparison of the Efficacy of Two Omeprazole Formulations in the Treatment of Equine Gastric Ulcer Syndrome in Racehorses: A Blinded, Randomized Clinical Trial.
    Journal of equine veterinary science, 2023, Volume: 126

    Topics: Animals; Anti-Ulcer Agents; Carcinoma, Squamous Cell; Horse Diseases; Horses; Omeprazole; Powders; S

2023
Effect of Changing Diet on Gastric Ulceration in Exercising Horses and Ponies After Cessation of Omeprazole Treatment.
    Journal of equine veterinary science, 2019, Volume: 83

    Topics: Animals; Gastroscopy; Horse Diseases; Horses; Omeprazole; Physical Conditioning, Animal; Stomach Ulc

2019
Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS).
    Equine veterinary journal, 2021, Volume: 53, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Omeprazole; Phenylbutazone

2021
Pharmacokinetic and pharmacodynamic effects of 2 registered omeprazole preparations and varying dose rates in horses.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:1

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cross-Over Studies; Female; Horse Diseases; Horses

2021
Preliminary investigations into a novel, long-acting, injectable, intramuscular formulation of omeprazole in the horse.
    Equine veterinary journal, 2017, Volume: 49, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Delayed-Action Preparations; Dosage Forms; Female; Gastric Acidity Deter

2017
Pharmacokinetic and pharmacodynamic effects of two omeprazole formulations on stomach pH and gastric ulcer scores.
    Equine veterinary journal, 2017, Volume: 49, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Dosage Forms; Gastric Acidity Determination; Horse Diseases; Horses; Hyd

2017
Comparison of aloe vera and omeprazole in the treatment of equine gastric ulcer syndrome.
    Equine veterinary journal, 2018, Volume: 50, Issue:1

    Topics: Aloe; Animals; Female; Gels; Horse Diseases; Horses; Male; Omeprazole; Phytotherapy; Stomach Ulcer

2018
Misoprostol is superior to combined omeprazole-sucralfate for the treatment of equine gastric glandular disease.
    Equine veterinary journal, 2019, Volume: 51, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Gastric Mucosa; Horse Diseases; Horse

2019
A comparison of two doses of omeprazole in the treatment of equine gastric ulcer syndrome: a blinded, randomised, clinical trial.
    Equine veterinary journal, 2014, Volume: 46, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Male;

2014
A comparison of three doses of omeprazole in the treatment of equine gastric ulcer syndrome: A blinded, randomised, dose-response clinical trial.
    Equine veterinary journal, 2015, Volume: 47, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Male;

2015
Administration of trimethoprim-sulphadimidine does not improve healing of glandular gastric ulceration in horses receiving omeprazole: a randomised, blinded, clinical study.
    BMC veterinary research, 2014, Aug-23, Volume: 10

    Topics: Animals; Anti-Ulcer Agents; Female; Horse Diseases; Horses; Male; Omeprazole; Single-Blind Method; S

2014
Efficacy of omeprazole paste in the prevention of gastric ulcers in 2 years old Thoroughbreds.
    The Journal of veterinary medical science, 2012, Volume: 74, Issue:8

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Horse Diseases; Horses; Omeprazole; Stomach Ulcer

2012
Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training.
    Journal of the American Veterinary Medical Association, 2002, Oct-15, Volume: 221, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Cross-Over Studies; Horse Diseases; Horses; Ointments; Omeprazole; Physi

2002
Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training.
    Journal of the American Veterinary Medical Association, 2005, May-15, Volume: 226, Issue:10

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Horse Di

2005
Efficacy of omeprazole paste for prevention of recurrence of gastric ulcers in horses in race training.
    Journal of the American Veterinary Medical Association, 2005, May-15, Volume: 226, Issue:10

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Horse Di

2005
Effects of treatment with omeprazole or ranitidine on gastric squamous ulceration in racing Thoroughbreds.
    Journal of the American Veterinary Medical Association, 2005, Nov-15, Volume: 227, Issue:10

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cross-Over Studies; Female; Horse Diseases; Horses

2005
Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration.
    Journal of the American Veterinary Medical Association, 2007, Jun-01, Volume: 230, Issue:11

    Topics: Animals; Anti-Ulcer Agents; Female; Horse Diseases; Horses; Male; Omeprazole; Physical Conditioning,

2007
Effects of omeprazole on healing of naturally-occurring gastric ulcers in thoroughbred racehorses.
    Equine veterinary journal, 1997, Volume: 29, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Gastroscopy; H

1997
Safety of omeprazole paste in foals and mature horses.
    Equine veterinary journal. Supplement, 1999, Issue:29

    Topics: Administration, Oral; Animals; Animals, Newborn; Enzyme Inhibitors; Female; Horse Diseases; Horses;

1999
Acceptability of a paste formulation and efficacy of high dose omeprazole in healing gastric ulcers in horses maintained in race training.
    Equine veterinary journal. Supplement, 1999, Issue:29

    Topics: Administration, Oral; Animals; Double-Blind Method; Enzyme Inhibitors; Female; Gastroscopy; Horse Di

1999
Effects of omeprazole paste on healing of spontaneous gastric ulcers in horses and foals: a field trial.
    Equine veterinary journal. Supplement, 1999, Issue:29

    Topics: Administration, Oral; Age Factors; Animals; Animals, Newborn; Breeding; Double-Blind Method; Enzyme

1999
Efficacy of omeprazole paste in the treatment and prevention of gastric ulcers in horses.
    Equine veterinary journal. Supplement, 1999, Issue:29

    Topics: Administration, Oral; Animals; Enzyme Inhibitors; Female; Florida; Gastroscopy; Horse Diseases; Hors

1999
Clinical trial to determine the effect of omeprazole given once or twice daily on gastric ulceration.
    Equine veterinary journal. Supplement, 1999, Issue:29

    Topics: Administration, Oral; Animals; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors;

1999

Other Studies

22 other studies available for omeprazole and Equine Diseases

ArticleYear
Evaluation of the treatment of equine glandular gastric disease with either long-acting-injectable or oral omeprazole.
    Veterinary medicine and science, 2022, Volume: 8, Issue:2

    Topics: Animals; Gastroscopy; Horse Diseases; Horses; Omeprazole; Retrospective Studies; Stomach Diseases

2022
Does lesion type or severity predict outcome of therapy for horses with equine glandular gastric disease? - A retrospective study.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Horse Diseases; Horses; Misoprostol; Omeprazole; Retrospective Studies; Stomach Ulcer; Sucr

2023
Does lesion type or severity predict outcome of therapy for horses with equine glandular gastric disease? - A retrospective study.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Horse Diseases; Horses; Misoprostol; Omeprazole; Retrospective Studies; Stomach Ulcer; Sucr

2023
Does lesion type or severity predict outcome of therapy for horses with equine glandular gastric disease? - A retrospective study.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Horse Diseases; Horses; Misoprostol; Omeprazole; Retrospective Studies; Stomach Ulcer; Sucr

2023
Does lesion type or severity predict outcome of therapy for horses with equine glandular gastric disease? - A retrospective study.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Horse Diseases; Horses; Misoprostol; Omeprazole; Retrospective Studies; Stomach Ulcer; Sucr

2023
Five- versus seven-day dosing intervals of extended-release injectable omeprazole in the treatment of equine squamous and glandular gastric disease.
    Equine veterinary journal, 2024, Volume: 56, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Horse Diseases; Horses; Omeprazole; Retrospective Studies; Stomac

2024
A study investigating the treatment of equine squamous gastric disease with long-acting injectable or oral omeprazole.
    Veterinary medicine and science, 2020, Volume: 6, Issue:2

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Female; Gastroscopy; Horse Diseases; Horses; Injec

2020
Omeprazole Reduces Calcium Digestibility in Thoroughbred Horses.
    Journal of equine veterinary science, 2020, Volume: 86

    Topics: Animals; Calcium, Dietary; Diet; Horse Diseases; Horses; Omeprazole; Proton Pump Inhibitors; Stomach

2020
Effect of oral administration of omeprazole on the microbiota of the gastric glandular mucosa and feces of healthy horses.
    Journal of veterinary internal medicine, 2020, Volume: 34, Issue:6

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Feces; Gastric Mucosa; Horse Diseases; Horses; Mi

2020
A pilot study comparing the effect of orally administered esomeprazole and omeprazole on gastric fluid pH in horses.
    New Zealand veterinary journal, 2017, Volume: 65, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Esomeprazole; Horse Diseases; Horses; Hydrogen-Ion Concentration; Omepra

2017
Comparison of the effect of two doses of omeprazole on the squamous gastric mucosa in thoroughbred racehorses.
    The Veterinary record, 2014, Sep-13, Volume: 175, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Breeding; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Hors

2014
Occupational contact dermatitis caused by omeprazole in a veterinary medicament.
    Contact dermatitis, 2014, Volume: 71, Issue:6

    Topics: Animals; Dermatitis, Allergic Contact; Dermatitis, Occupational; Gastroesophageal Reflux; Horse Dise

2014
Occupational allergic contact dermatitis caused by omeprazole in a horse breeder.
    Contact dermatitis, 2014, Volume: 71, Issue:6

    Topics: Adult; Animals; Cross Reactions; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hor

2014
The effects of dose and diet on the pharmacodynamics of omeprazole in the horse.
    Equine veterinary journal, 2017, Volume: 49, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cross-Over Studies; Diet; Dose-Response Relationship, Drug; Gastric Acid

2017
Effect of gastric ulceration on physiologic responses to exercise in horses.
    American journal of veterinary research, 2009, Volume: 70, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Female; Food Deprivation; Gastric Mucosa; Horse Diseases; Horses; Male;

2009
Ulcerative cystitis associated with phenylbutazone administration in two horses.
    Journal of the American Veterinary Medical Association, 2011, Aug-15, Volume: 239, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cystitis; Hematuria; Horse Dise

2011
Treatment with histamine-type 2 receptor antagonists and omeprazole increase the risk of diarrhoea in neonatal foals treated in intensive care units.
    Equine veterinary journal. Supplement, 2012, Issue:41

    Topics: Animals; Animals, Newborn; Anti-Ulcer Agents; Clostridium Infections; Diarrhea; Female; Histamine H2

2012
Efficacy of a paste formulation of omeprazole for the treatment of naturally occurring gastric ulcers in training standardbred racehorses in Canada.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2003, Volume: 44, Issue:7

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Gastrosc

2003
Odds of moderate or severe gastric ulceration in racehorses receiving antiulcer medications.
    Journal of the American Veterinary Medical Association, 2003, Aug-01, Volume: 223, Issue:3

    Topics: Age Factors; Animals; Anti-Ulcer Agents; Breeding; Case-Control Studies; Female; Gastroscopy; Horse

2003
Effect of GastroGard and three compounded oral omeprazole preparations on 24 h intragastric pH in gastrically cannulated mature horses.
    Equine veterinary journal, 2003, Volume: 35, Issue:7

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Drug Compounding; Female; Gastric Acid; Gastric Mu

2003
Evaluation of urine sucrose concentration for detection of gastric ulcers in horses.
    American journal of veterinary research, 2004, Volume: 65, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Endoscopy; Horse Diseases; Horses;

2004
Chronic diarrhea and weight loss in three horses.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Desulfovibrionaceae Infections; Diarrhea; Endoscopy, Gastrointestinal; E

2006
Cholelithiasis and hepatic fibrosis in a standardbred mare.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Blood Cell Count; Blood Chemical Analysis

2006
The effect of omeprazole paste on intragastric pH in clinically ill neonatal foals.
    Equine veterinary journal, 2008, Volume: 40, Issue:1

    Topics: Administration, Oral; Animals; Animals, Newborn; Anti-Ulcer Agents; Female; Gastric Acid; Gastric Ac

2008
Effects of orally administered enteric-coated omeprazole on gastric acid secretion in horses.
    American journal of veterinary research, 1999, Volume: 60, Issue:8

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Female; Gastric Acidity Determination; Gastric Jui

1999