omeprazole has been researched along with Enterocolitis, Pseudomembranous in 7 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 38-year-old Caucasian man with mild hypertension and no other significant medical history developed profound erectile dysfunction within 2 days of initiating over-the-counter omeprazole therapy, with erectile function rapidly normalizing following discontinuation of the drug." | 8.02 | Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report. ( Perry, TW, 2021) |
| "A 38-year-old Caucasian man with mild hypertension and no other significant medical history developed profound erectile dysfunction within 2 days of initiating over-the-counter omeprazole therapy, with erectile function rapidly normalizing following discontinuation of the drug." | 4.02 | Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report. ( Perry, TW, 2021) |
| "We describe a 54-year-old man with Helicobacter pylori (+) duodenal ulcer who developed Clostridium difficile associated colitis, 5 days after commencing a 'triple' regimen consisting of omeprazole 20 mg b." | 3.70 | Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. ( Archimandritis, A; Katsorida, M; Souyioultzis, S; Tzivras, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Perry, TW | 1 |
| Freedberg, DE | 1 |
| Toussaint, NC | 1 |
| Chen, SP | 1 |
| Ratner, AJ | 1 |
| Whittier, S | 1 |
| Wang, TC | 1 |
| Wang, HH | 1 |
| Abrams, JA | 1 |
| Rai, R | 1 |
| Rai, S | 1 |
| Kubo, N | 1 |
| Kochi, S | 1 |
| Ariyama, I | 1 |
| Murata, M | 1 |
| Furusyo, N | 1 |
| Hayashi, J | 1 |
| Schweigart, U | 1 |
| Franck, H | 1 |
| Schepp, W | 1 |
| Lehn, N | 1 |
| Becker, K | 1 |
| Classen, M | 1 |
| Archimandritis, A | 1 |
| Souyioultzis, S | 1 |
| Katsorida, M | 1 |
| Tzivras, M | 1 |
| Lau, CF | 1 |
| Hui, PK | 1 |
| Fung, TT | 1 |
| Tung, SY | 1 |
| Wong, AM | 1 |
| Loo, CK | 1 |
| Lam, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Gastric Acid Suppression on the Colonic Microbiome[NCT01901276] | Phase 4 | 12 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)[NCT02893709] | 36 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for omeprazole and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis, | 2015 |
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis, | 2015 |
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis, | 2015 |
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis, | 2015 |
6 other studies available for omeprazole and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report.
Topics: Adult; Aged; Enterocolitis, Pseudomembranous; Erectile Dysfunction; Humans; Male; Omeprazole; Proton | 2021 |
Pseudomembranous colitis requiring surgical intervention following triple therapy for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Clarithromycin; Drug Therapy, Combination; Enterocol | 2002 |
[Pseudomembranous colitis after Helicobacter pylori eradication therapy].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Ag | 2006 |
[Toxic megacolon after Helicobacter pylori eradication therapy].
Topics: Aged; Amoxicillin; Anti-Ulcer Agents; Colon; Diagnosis, Differential; Drug Therapy, Combination; Ent | 1997 |
Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori.
Topics: Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Duodenal Ulcer; Enterocolitis, Pseudom | 1998 |
Pseudomembranous colitis without diarrhoea following Helicobacter pylori eradication therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents | 2001 |