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omeprazole and Duodenal Reflux

omeprazole has been researched along with Duodenal Reflux in 12 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Both sucralfate and rabeprazole therapies are effective treatment options in the patients with alkaline gastritis when compared with observation."9.10Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment. ( Cammarota, G; Candelli, M; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Nista, EC; Santarelli, L, 2003)
"The GABA(B) receptor agonist baclofen improves duodenal reflux and associated reflux symptoms that persist during PPI therapy."9.10Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. ( Janssens, J; Koek, GH; Lerut, T; Sifrim, D; Tack, J, 2003)
" However, little is known about the effect of omeprazole on duodenogastric reflux (DGR) and duodenogastro-oesophageal reflux (DGOR)."9.08Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus. ( Anggiansah, A; Manifold, DK; Marshall, RE; Owen, WA; Owen, WJ, 1998)
"Gastric secretion was measured in nine patients with duodenal ulcer before, and after treatment for four weeks with omeprazole 20 mg or 40 mg daily."7.67Basal, sham feed and pentagastrin stimulated gastric acid, pepsin and electrolytes after omeprazole 20 mg and 40 mg daily. ( Baron, JH; Barr, JA; Bush, A; Collier, N; Cope, L; Gribble, RJ; Spencer, J; Thompson, JN, 1985)
"Both sucralfate and rabeprazole therapies are effective treatment options in the patients with alkaline gastritis when compared with observation."5.10Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment. ( Cammarota, G; Candelli, M; Cremonini, F; Gabrielli, M; Gasbarrini, A; Gasbarrini, G; Nista, EC; Santarelli, L, 2003)
"The GABA(B) receptor agonist baclofen improves duodenal reflux and associated reflux symptoms that persist during PPI therapy."5.10Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. ( Janssens, J; Koek, GH; Lerut, T; Sifrim, D; Tack, J, 2003)
" However, little is known about the effect of omeprazole on duodenogastric reflux (DGR) and duodenogastro-oesophageal reflux (DGOR)."5.08Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus. ( Anggiansah, A; Manifold, DK; Marshall, RE; Owen, WA; Owen, WJ, 1998)
"Gastric secretion was measured in nine patients with duodenal ulcer before, and after treatment for four weeks with omeprazole 20 mg or 40 mg daily."3.67Basal, sham feed and pentagastrin stimulated gastric acid, pepsin and electrolytes after omeprazole 20 mg and 40 mg daily. ( Baron, JH; Barr, JA; Bush, A; Collier, N; Cope, L; Gribble, RJ; Spencer, J; Thompson, JN, 1985)
"However, recent work suggests that duodenogastric reflux (DGR) may be reduced by omeprazole."2.69Effect of omeprazole on antral duodenogastric reflux in Barrett oesophagus. ( Anggiansah, A; Manifold, DK; Marshall, RE; Owen, WJ, 2000)
"Studying role of duodenogastric reflux (DGR) in pathogenesis and sanogenesis of duodenal ulcer (DU)."1.37[Characteristics of duodenogastric reflux in duodenal ulcer patients and its dynamics after Helicobacter pylori eradication]. ( Kolesnikova, IIu; Liubskaia, LA; Volkov, VS, 2011)
"Gastroesophageal reflux disease patients who continued to report symptoms 3 times a week for 3 months while on PPI once a day were assigned to the PPI failure group."1.35Comparison of the degree of duodenogastroesophageal reflux and acid reflux between patients who failed to respond and those who were successfully treated with a proton pump inhibitor once daily. ( Fass, R; Gasiorowska, A; Koenig, K; Krupinski, E; Moty, B; Navarro-Rodriguez, T; Perry, ZH; Powers, J; Wendel, C, 2009)
"Duodenogastric reflux is known to cause an increased frequency of cancer in the glandular portion of the stomach in rats."1.32Lanzoprazole promotes gastric carcinogenesis in rats with duodenogastric reflux. ( Maartmann-Moe, H; Viste, A; Waldum, H; Øvrebø, K, 2004)
"None of the rats developed esophageal cancer, but esophageal mucosal hyperplasia was more pronounced in rats receiving omeprazole."1.30Gastric acid blockade with omeprazole promotes gastric carcinogenesis induced by duodenogastric reflux. ( Adrian, TE; Hinder, RA; Perdikis, G; Profanter, C; Smyrk, T; Wetscher, GJ, 1999)
"We investigated whether duodenogastric reflux (DGR) together with gastroesophageal reflux causes growth stimulation of the foregut mucosa and if additional gastric acid suppression enhances the effect of DGR."1.29Duodenogastric reflux causes growth stimulation of foregut mucosa potentiated by gastric acid blockade. ( Adrian, TE; Hinder, RA; Klingler, PJ; Kretchmar, D; Perdikis, G; Smyrk, T; Stinson, R; Wetscher, GJ, 1996)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's4 (33.33)18.2507
2000's5 (41.67)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Monteiro, RLR1
Kobayasi, MAMR1
Araujo, MR1
Monteiro, DR1
Andreollo, NA1
Gasiorowska, A1
Navarro-Rodriguez, T1
Wendel, C1
Krupinski, E1
Perry, ZH1
Koenig, K1
Moty, B1
Powers, J1
Fass, R1
Kolesnikova, IIu1
Volkov, VS1
Liubskaia, LA1
Santarelli, L1
Gabrielli, M1
Candelli, M1
Cremonini, F1
Nista, EC1
Cammarota, G1
Gasbarrini, G1
Gasbarrini, A1
Koek, GH1
Sifrim, D1
Lerut, T1
Janssens, J1
Tack, J1
Viste, A1
Øvrebø, K1
Maartmann-Moe, H1
Waldum, H1
Wetscher, GJ2
Hinder, RA2
Kretchmar, D1
Stinson, R1
Perdikis, G2
Smyrk, T2
Klingler, PJ1
Adrian, TE2
Waring, JP1
Hunter, JG1
Marshall, RE2
Anggiansah, A2
Manifold, DK2
Owen, WA1
Owen, WJ2
Profanter, C1
Thompson, JN1
Barr, JA1
Collier, N1
Spencer, J1
Bush, A1
Cope, L1
Gribble, RJ1
Baron, JH1

Trials

4 trials available for omeprazole and Duodenal Reflux

ArticleYear
Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Analysis of Variance; Anti-Ulcer Agents; Benzi

2003
Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors.
    Gut, 2003, Volume: 52, Issue:10

    Topics: Adult; Baclofen; Chi-Square Distribution; Drug Resistance; Drug Therapy, Combination; Duodenogastric

2003
Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus.
    Gut, 1998, Volume: 43, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Bile Reflux; Bilirubin; Drug A

1998
Effect of omeprazole on antral duodenogastric reflux in Barrett oesophagus.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:8

    Topics: Adolescent; Adult; Aged; Barrett Esophagus; Bilirubin; Duodenogastric Reflux; Endoscopy, Gastrointes

2000

Other Studies

8 other studies available for omeprazole and Duodenal Reflux

ArticleYear
Omeprazole and adenocarcinoma in the stomach of rats submitted to duodenogastric reflux. Is there a protective effect?
    Acta cirurgica brasileira, 2020, Volume: 35, Issue:9

    Topics: Adenocarcinoma; Animals; Duodenogastric Reflux; Gastric Mucosa; Humans; Omeprazole; Proton Pump Inhi

2020
Comparison of the degree of duodenogastroesophageal reflux and acid reflux between patients who failed to respond and those who were successfully treated with a proton pump inhibitor once daily.
    The American journal of gastroenterology, 2009, Volume: 104, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Duodenogastric Reflux; Esophageal pH M

2009
[Characteristics of duodenogastric reflux in duodenal ulcer patients and its dynamics after Helicobacter pylori eradication].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2011, Issue:5

    Topics: Adult; Amoxicillin; Clarithromycin; Drug Therapy, Combination; Duodenal Ulcer; Duodenogastric Reflux

2011
Lanzoprazole promotes gastric carcinogenesis in rats with duodenogastric reflux.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2004, Volume: 7, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Administration, Oral; Animals; Duodenogastr

2004
Duodenogastric reflux causes growth stimulation of foregut mucosa potentiated by gastric acid blockade.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:11

    Topics: Animals; DNA; Duodenogastric Reflux; Esophagus; Gastric Acid; Gastric Acidity Determination; Gastric

1996
Patients failing moderately high doses of omeprazole.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:5

    Topics: Anti-Ulcer Agents; Duodenogastric Reflux; Humans; Laparoscopy; Omeprazole; Proton Pump Inhibitors; T

1997
Gastric acid blockade with omeprazole promotes gastric carcinogenesis induced by duodenogastric reflux.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:6

    Topics: Adenocarcinoma; Animals; Anti-Ulcer Agents; Disease Models, Animal; Duodenogastric Reflux; Esophagea

1999
Basal, sham feed and pentagastrin stimulated gastric acid, pepsin and electrolytes after omeprazole 20 mg and 40 mg daily.
    Gut, 1985, Volume: 26, Issue:10

    Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Duodenogastric Reflux; Electrolytes; Feedi

1985