Page last updated: 2024-11-01

omeprazole and Duodenal Diseases

omeprazole has been researched along with Duodenal Diseases in 15 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).

Research Excerpts

ExcerptRelevanceReference
" Our purpose was to evaluate the occurrence of mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and to compare the effects of cimetidine, famotidine, and omeprazole."9.08Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole. ( Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P, 1996)
" Our purpose was to evaluate the occurrence of mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and to compare the effects of cimetidine, famotidine, and omeprazole."5.08Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole. ( Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P, 1996)
" He was successfully treated by increasing his dosage of omeprazol (20 mg/day) for two weeks."1.35Acute gastroduodenal injury after ingestion of diluted herbicide pendimethalin. ( Azuhata, H; Katoh, H; Kuwano, H; Tsukada, K, 2009)
"Forty of 78 patients dying of oesophageal cancer had the disease present at registration."1.32Mortality study of 18 000 patients treated with omeprazole. ( Bateman, DN; Colin-Jones, D; Hartz, S; Langman, M; Logan, RF; Mant, J; Murphy, M; Paterson, KR; Rowsell, R; Thomas, S; Vessey, M, 2003)
" In a group of 34 patients studied prospectively, high dosage (300 mg orally bid) therapy with the H2-antagonist ranitidine for 8 wk significantly improved symptoms and endoscopic appearance (p < 0."1.29Clinical and pathologic features of the nodular duodenum. ( Triadafilopoulos, G, 1993)
"A case of ulcerative colitis complicated with gastric and duodenal lesions is reported."1.29Ulcerative colitis complicated by gastroduodenal lesions. ( Bamba, T; Fujiyama, Y; Inoue, H; Koyama, S; Okada, K; Sasaki, M; Yoshioka, U, 1996)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (40.00)18.2507
2000's9 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tseng, GY1
Jeng, TK1
Yang, HB1
Lin, HJ1
Burkov, SG1
Arutiunov, AT1
Gurova, NIu1
Lobanova, EG1
Nikiforov, PA1
Okoemov, MN1
Cherezova, IN1
Chugunnikova, LI1
Tsukada, K1
Azuhata, H1
Katoh, H1
Kuwano, H1
Bateman, DN1
Colin-Jones, D1
Hartz, S1
Langman, M1
Logan, RF1
Mant, J1
Murphy, M1
Paterson, KR1
Rowsell, R1
Thomas, S1
Vessey, M1
Todd, JA1
Basu, KK1
de Caestecker, JS1
Mégraud, F1
Triadafilopoulos, G1
Goenka, MK1
Kochhar, R1
Chakrabarti, A1
Kumar, A1
Gupta, O1
Talwar, P1
Mehta, SK1
Sasaki, M1
Okada, K1
Koyama, S1
Yoshioka, U1
Inoue, H1
Fujiyama, Y1
Bamba, T1
De Francesco, V1
Stoppino, V1
Germano, MP1
Frigerio, P1
De Paolis, PL1
Faleo, D1
Sugimoto, M1
Kajimura, M1
Hanai, H1
Kaneko, E1
Pilotto, A1
Di Mario, F1
Franceschi, M1
Leandro, G1
Battaglia, G1
Germanà, B1
Marin, R1
Valerio, G1
Miehsler, W1
Püspök, A1
Oberhuber, T1
Vogelsang, H1
Chan, KL1
Zhou, H1
Ng, DK1
Tam, PK1
Gabbrielli, M1
Pennati, P1
Trallori, G1
Vannozzi, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Personalized Treatment for Refractory H Pylori Infection[NCT02547025]126 participants (Actual)Interventional2012-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Duodenal Diseases

ArticleYear
Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole shown in vitro.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Cells, Cultured; Chemotherapy, Adjuvant; Duodenal

1995

Trials

4 trials available for omeprazole and Duodenal Diseases

ArticleYear
[NSAID-gastropathy: state-of-the-art therapy optimization capabilities in outpatient practice].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2008, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Admin

2008
Normalization of oesophageal pH does not guarantee control of duodenogastro-oesophageal reflux in Barrett's oesophagus.
    Alimentary pharmacology & therapeutics, 2005, Apr-15, Volume: 21, Issue:8

    Topics: Aged; Anti-Ulcer Agents; Barrett Esophagus; Duodenal Diseases; Esophagoscopy; Esophagus; Female; Gas

2005
Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole.
    Journal of clinical gastroenterology, 1996, Volume: 23, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Candidiasis; Cimetidine; Duodenal Diseases; Duodenal Ulcer; Famotidine; Fe

1996
Pantoprazole versus one-week Helicobacter pylori eradication therapy for the prevention of acute NSAID-related gastroduodenal damage in elderly subjects.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Aging; Amoxicillin; Anti-Bacterial Agent

2000

Other Studies

10 other studies available for omeprazole and Duodenal Diseases

ArticleYear
Is there a role for intravenous omeprazole in patients with duodenal diverticular bleeding after successful initial endoscopic hemostasis?
    Gastrointestinal endoscopy, 2008, Volume: 68, Issue:2

    Topics: Combined Modality Therapy; Diverticulum; Dose-Response Relationship, Drug; Drug Administration Sched

2008
Acute gastroduodenal injury after ingestion of diluted herbicide pendimethalin.
    Singapore medical journal, 2009, Volume: 50, Issue:3

    Topics: Accidents, Home; Acute Disease; Aged; Aniline Compounds; Anti-Ulcer Agents; Duodenal Diseases; Herbi

2009
Mortality study of 18 000 patients treated with omeprazole.
    Gut, 2003, Volume: 52, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cause of Death; Child; Duodenal Disea

2003
Clinical and pathologic features of the nodular duodenum.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Duodenal Diseases; Duodenitis; Duodenoscopy; Duodenum; Human

1993
Ulcerative colitis complicated by gastroduodenal lesions.
    Journal of gastroenterology, 1996, Volume: 31, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Ulcer Agents; Colitis, Ulcerative; Duodenal Diseases; Duo

1996
Ulcer activity but not duodenal stenosis regresses after eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1999, Volume: 29, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Duodenal Diseases; Duodenal Ulcer; Duodenoscopy; Female; Follow-Up Studies

1999
Prevention of hemorrhage from intradiverticular ulcer in the duodenum by Helicobacter pylori eradication.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:2

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Diverticulum; Drug Ther

2000
Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tract.
    Inflammatory bowel diseases, 2001, Volume: 7, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Crohn Disease; Data Interpretatio

2001
A prospective study of a one-week nonbismuth quadruple therapy for childhood Helicobacter pylori infection.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Child; Child, Preschool; C

2001
Use of intravenous omeprazole in emergency cases of gastroduodenal hemorrhage.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:9

    Topics: Duodenal Diseases; Emergencies; Female; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous

1992