Page last updated: 2024-11-01

omeprazole and Drug Hypersensitivity

omeprazole has been researched along with Drug Hypersensitivity in 23 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
" The present study was designed to test the hypothesis that a triple therapy with pantoprazole, clarithromycin and amoxycillin cures the infection in > or = 80% of duodenal ulcer patients infected with H."9.08Efficacy and tolerability of a one-week triple therapy consisting of pantoprazole, clarithromycin and amoxycillin for cure of Helicobacter pylori infection in patients with duodenal ulcer. ( Labenz, J; Lütke, A; Stolte, M; Tillenburg, B; Weismüller, J, 1997)
"Omeprazole is a proton pump inhibitor which reduces both basal and stimulated gastric acid secretion by inhibiting the parietal cell enzyme H(+)-K(+)-adenosine triphosphatase."5.33[Anaphylaxis caused by omeprazole]. ( Bauer, C; Fackler, I; Kamann, S; Przybilla, B, 2006)
" The present study was designed to test the hypothesis that a triple therapy with pantoprazole, clarithromycin and amoxycillin cures the infection in > or = 80% of duodenal ulcer patients infected with H."5.08Efficacy and tolerability of a one-week triple therapy consisting of pantoprazole, clarithromycin and amoxycillin for cure of Helicobacter pylori infection in patients with duodenal ulcer. ( Labenz, J; Lütke, A; Stolte, M; Tillenburg, B; Weismüller, J, 1997)
"Although rare, anaphylactic reactions induced by proton pump inhibitors have been reported."1.35Nine cases of omeprazole allergy: cross-reactivity between proton pump inhibitors. ( Alarcón, E; Blasco, A; Del Pozo, MD; Escudero, R; González, I; Lobera, T; Navarro, B; Venturini, M, 2009)
"Omeprazole is a proton pump inhibitor which reduces both basal and stimulated gastric acid secretion by inhibiting the parietal cell enzyme H(+)-K(+)-adenosine triphosphatase."1.33[Anaphylaxis caused by omeprazole]. ( Bauer, C; Fackler, I; Kamann, S; Przybilla, B, 2006)
"Omeprazole is a potent proton pump inhibitor and usually is well tolerated."1.31Cutaneous leucocytoclastic vasculitis associated with omeprazole. ( Lurie, M; Odeh, M; Oliven, A, 2002)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's11 (47.83)29.6817
2010's6 (26.09)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Zhou, Y1
Ye, Z1
Lu, J1
Miao, S1
Lu, X1
Sun, H1
Wu, J1
Wang, Y1
Huang, Y1
Glick, A1
Sista, V1
Johnson, C1
Dohr, J1
Hunzelmann, N1
Brown, A1
Sánchez-Morillas, L1
Rojas Pérez-Ezquerra, P1
González Mendiola, R1
Gómez-Tembleque Ubeda, P1
Santos Alvarez, A1
Laguna-Martínez, JJ1
Gisbert, JP2
Barrio, J2
Modolell, I1
Molina-Infante, J1
Aisa, AP1
Castro-Fernández, M2
Rodrigo, L2
Cosme, A2
Gisbert, JL2
Fernández-Bermejo, M1
Marcos, S2
Marín, AC1
McNicholl, AG1
Lobera, T1
Navarro, B1
Del Pozo, MD1
González, I1
Blasco, A1
Escudero, R1
Venturini, M1
Alarcón, E1
Tayman, C1
Mete, E1
Catal, F1
Tonbul, A1
Pérez-Aisa, A1
Moreno-Otero, R1
Schmutz, JL1
Barbaud, A1
Trechot, P1
Sobrevia Elfau, MT1
Garcés Sotillos, M1
Ferrer Clavería, L1
Segura Arazuri, N1
Monzón Ballarin, S1
Colás Sanz, C1
Abdul Razzak, E1
Tomás, M1
Tornero, P1
Herrero, T1
Abraham, D1
Saltoun, CA1
Gamboa, PM1
Sanz, ML1
Urrutia, I1
Jáuregui, I1
Antépara, I1
Diéguez, I1
De Weck, AL1
Porcel, S1
Rodríguez, A1
Jiménez, S1
Alvarado, M1
Hernández, J1
Kamann, S1
Bauer, C1
Fackler, I1
Przybilla, B1
Pérez Pimiento, AJ1
Prieto Lastra, L1
Rodríguez Cabreros, MI1
González Sánchez, LA1
Mosquera, MR1
Cubero, AG1
Gonzalez-Mendiola, R1
Martínez Borque, N1
Palomeque Rodríguez, T1
Torrecillas Toro, M1
Martínez Bohigas, D1
Saha, N1
Sachdev, A1
Bhasin, DK1
Sankaranahyanan, A1
Khosla, PP1
Singh, K1
Sharma, PL1
Ottervanger, JP1
Phaff, RA1
Vermeulen, EG1
Stricker, BH1
Labenz, J1
Tillenburg, B1
Weismüller, J1
Lütke, A1
Stolte, M1
Pérez Roldán, F1
de los Ríos, IL1
Rodríguez Quinzaños, E1
Odeh, M1
Lurie, M1
Oliven, A1
Kaatz, M1
Bauer, A1
Hipler, C1
Elsner, P1

Trials

2 trials available for omeprazole and Drug Hypersensitivity

ArticleYear
Clinical evaluation of the effect of omeprazole, cimetidine, famotidine and ranitidine on histamine induced cutaneous wheal and flare response.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7

    Topics: Adult; Cimetidine; Drug Hypersensitivity; Dyspepsia; Famotidine; Female; Histamine; Histamine H2 Ant

1993
Efficacy and tolerability of a one-week triple therapy consisting of pantoprazole, clarithromycin and amoxycillin for cure of Helicobacter pylori infection in patients with duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

1997

Other Studies

21 other studies available for omeprazole and Drug Hypersensitivity

ArticleYear
Long-term changes in the gut microbiota after 14-day bismuth quadruple therapy in penicillin-allergic children.
    Helicobacter, 2020, Volume: 25, Issue:5

    Topics: Adolescent; Anti-Bacterial Agents; Bismuth; Child; Clarithromycin; Cross-Sectional Studies; Drug Hyp

2020
Oral Manifestations of Commonly Prescribed Drugs.
    American family physician, 2020, 11-15, Volume: 102, Issue:10

    Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associ

2020
[Immediate type reactions to proton pump inhibitors using pantoprazole and omeprazole as examples].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2018, Volume: 69, Issue:2

    Topics: Administration, Oral; Anaphylaxis; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Female; H

2018
Eleven cases of omeprazole hypersensitivity: diagnosis and study of cross-reactivity.
    Journal of investigational allergology & clinical immunology, 2014, Volume: 24, Issue:2

    Topics: Adult; Cross Reactions; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Omeprazole; Proton

2014
Helicobacter pylori first-line and rescue treatments in the presence of penicillin allergy.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:2

    Topics: Antacids; Anti-Bacterial Agents; Bismuth; Breath Tests; Clarithromycin; Drug Administration Schedule

2015
Nine cases of omeprazole allergy: cross-reactivity between proton pump inhibitors.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:1

    Topics: Adult; Anaphylaxis; Cross Reactions; Drug Hypersensitivity; Female; Humans; Middle Aged; Omeprazole;

2009
Hypersensitivity reaction to omeprazole in a child.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:1

    Topics: Adolescent; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Male; Omeprazole; Proton Pum

2009
Helicobacter pylori first-line treatment and rescue option containing levofloxacin in patients allergic to penicillin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2010, Volume: 42, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration

2010
[Delayed hypersensitivity to sodium lauryl sulphate in omeprazole].
    Annales de dermatologie et de venereologie, 2009, Volume: 136, Issue:12

    Topics: Anti-Ulcer Agents; Drug Hypersensitivity; Excipients; Female; Humans; Hypersensitivity, Delayed; Mid

2009
Study of cross-reactivity between proton pump inhibitors.
    Journal of investigational allergology & clinical immunology, 2010, Volume: 20, Issue:2

    Topics: Adult; Angioedema; Cross Reactions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immedia

2010
Nine cases of allergy to omeprazole.
    Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Cross Reactions; Drug Hypersensitivity; Enzyme Inhib

2012
Facial swelling and eosinophilia in a 44-year-old woman.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 89, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Angioedema; Cefuroxime; Cetirizine; Diagnosis, Diffe

2002
CD63 expression by flow cytometry in the in vitro diagnosis of allergy to omeprazole.
    Allergy, 2003, Volume: 58, Issue:6

    Topics: Aged; Antigens, CD; Drug Hypersensitivity; Flow Cytometry; Humans; Male; Omeprazole; Platelet Membra

2003
Allergy to lansoprazole: study of cross-reactivity among proton-pump inhibitors.
    Allergy, 2005, Volume: 60, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Cross Reactions; Drug Hypersensitivi

2005
[Anaphylaxis caused by omeprazole].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:11

    Topics: Anaphylaxis; Angioedema; Anti-Ulcer Agents; Basophil Degranulation Test; Basophils; Drug Hypersensit

2006
Hypersensitivity to lansoprazole and rabeprazole with tolerance to other proton pump inhibitors.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Cross Reactions; Drug Hypersensitivi

2006
Type I allergic reaction to benzimidazole antihelmintics.
    Allergy, 2007, Volume: 62, Issue:6

    Topics: Albendazole; Anthelmintics; Benzimidazoles; Drug Hypersensitivity; Female; Humans; Mebendazole; Midd

2007
Anaphylaxis to omeprazole.
    The Journal of allergy and clinical immunology, 1996, Volume: 97, Issue:6

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Male; Middle Aged; Omeprazole

1996
Lansoprazole and glottis edema.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Drug Hypersensitivity; Humans; La

1999
Cutaneous leucocytoclastic vasculitis associated with omeprazole.
    Postgraduate medical journal, 2002, Volume: 78, Issue:916

    Topics: Aged; Anti-Ulcer Agents; Drug Hypersensitivity; Duodenal Ulcer; Female; Humans; Omeprazole; Vasculit

2002
Nonallergic anaphylaxis to pantoprazole.
    Allergy, 2002, Volume: 57, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anaphylaxis; Benzimidazoles; Diagnosis, Differential; Drug

2002