omeprazole has been researched along with Diseases of Pharynx in 15 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Empiric omeprazole therapy is a reasonable, initial approach to patients with suspected gastroesophageal reflux-related posterior laryngitis." | 7.69 | Empiric trial of high-dose omeprazole in patients with posterior laryngitis: a prospective study. ( Delgaudio, JM; Grist, WJ; Gussack, G; Waring, JP; Wo, JM, 1997) |
| " One of 21 patients receiving omeprazole developed a fistula in comparison to 6 of 19 patients in the placebo group (p = ." | 5.20 | Effect of perioperative proton pump inhibitors on the incidence of pharyngocutaneous fistula after total laryngectomy: a prospective randomized controlled trial. ( Fagan, JJ; Stephenson, KA, 2015) |
| " Patients with symptoms suspected to be due to laryngopharyngeal reflux (based on a positive oesophageal pH test and/or changes on videolaryngoscopy consistent with posterior laryngitis) were treated with omeprazole for at least two to three months." | 3.70 | Presumed laryngo-pharyngeal reflux: investigate or treat? ( Fraser, AG; Gillibrand, J; Morton, RP, 2000) |
| "Empiric omeprazole therapy is a reasonable, initial approach to patients with suspected gastroesophageal reflux-related posterior laryngitis." | 3.69 | Empiric trial of high-dose omeprazole in patients with posterior laryngitis: a prospective study. ( Delgaudio, JM; Grist, WJ; Gussack, G; Waring, JP; Wo, JM, 1997) |
| "Treatment with omeprazole significantly improved QL in both LPR subgroups patients." | 2.73 | Quality of life in laryngopharyngeal reflux patients. ( Adamonis, K; Siupsinskiene, N; Toohill, RJ, 2007) |
| "Idiopathic hoarseness as a single symptom increases the odds ratio for laryngopharyngeal reflux disease 85 times." | 1.31 | [Typical and atypical symptoms of laryngopharyngeal reflux disease]. ( Jonaitis, L; Pribuisiene, R; Uloza, V, 2002) |
| "In the dysphagia group, 48 of 54 patients (89%) had edema of the posterior larynx, and 42 of 54 (78%) had laryngopharyngeal sensory deficits." | 1.31 | Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia. ( Aviv, JE; Close, LG; Kaplan, ST; Liu, H; Parides, M, 2000) |
| " Results were further analyzed to compare failure rates based on different dosage regimens." | 1.31 | Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux. ( Amin, MR; Digges, N; Johnson, P; Koufman, JA; Postma, GN, 2001) |
| "The relationship between gastroesophageal reflux disease and these symptoms has been studied but remains unclear." | 1.29 | Role of gastroesophageal reflux disease in patients with cervical symptoms. ( Freeman, J; Goldberg, M; Mendelsohn, M; Rival, R; Rosgen, S; Wong, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 11 (73.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stephenson, KA | 1 |
| Fagan, JJ | 1 |
| Aladag, I | 1 |
| Eyibilen, A | 1 |
| Guven, M | 1 |
| Erkokmaz, U | 1 |
| Pribuisiene, R | 1 |
| Uloza, V | 1 |
| Jonaitis, L | 1 |
| Hill, RK | 1 |
| Simpson, CB | 1 |
| Velazquez, R | 1 |
| Larson, N | 1 |
| Carrau, RL | 1 |
| Khidr, A | 1 |
| Gold, KF | 1 |
| Crawley, JA | 1 |
| Hillson, EM | 1 |
| Koufman, JA | 3 |
| Pashos, CL | 1 |
| Stavroulaki, P | 1 |
| Lancaster, JL | 1 |
| Gosh, S | 1 |
| Sethi, R | 1 |
| Tripathi, S | 1 |
| Siupsinskiene, N | 1 |
| Adamonis, K | 1 |
| Toohill, RJ | 1 |
| Rival, R | 1 |
| Wong, R | 1 |
| Mendelsohn, M | 1 |
| Rosgen, S | 1 |
| Goldberg, M | 1 |
| Freeman, J | 1 |
| Wo, JM | 1 |
| Grist, WJ | 1 |
| Gussack, G | 1 |
| Delgaudio, JM | 1 |
| Waring, JP | 1 |
| de Caestecker, J | 1 |
| Fraser, AG | 1 |
| Morton, RP | 1 |
| Gillibrand, J | 1 |
| Aviv, JE | 1 |
| Liu, H | 1 |
| Parides, M | 1 |
| Kaplan, ST | 1 |
| Close, LG | 1 |
| Belafsky, PC | 1 |
| Postma, GN | 2 |
| Amin, MR | 1 |
| Johnson, P | 1 |
| Digges, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Care For Infants With Laryngomalacia: A Pilot Randomized Controlled Trial of Omeprazole Versus Placebo[NCT01782560] | Phase 1 | 0 participants (Actual) | Interventional | 2013-02-28 | Withdrawn (stopped due to Unable to recruit a sufficient amount of subjects) | ||
| A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265] | Phase 4 | 18 participants (Actual) | Interventional | 2006-08-31 | Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.) | ||
| A Prospective Evaluation of the Utility, Optimal Cutoff and Positive Predictive Value of a Pharyngeal pH Probe for Predicting Proton Pump Inhibitor Response in Treatment Naive Laryngopharyngeal Reflux[NCT01755221] | 80 participants (Anticipated) | Interventional | 2012-08-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for omeprazole and Diseases of Pharynx
| Article | Year |
|---|---|
Diagnostic and management problems of laryngopharyngeal reflux disease in children.
Topics: Child; Gastric Acidity Determination; Gastroesophageal Reflux; Humans; Infant; Laryngeal Diseases; L | 2006 |
Medical therapy for supraesophageal complications of gastroesophageal reflux.
Topics: Clinical Trials as Topic; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Laryngeal Disea | 1997 |
2 trials available for omeprazole and Diseases of Pharynx
| Article | Year |
|---|---|
Effect of perioperative proton pump inhibitors on the incidence of pharyngocutaneous fistula after total laryngectomy: a prospective randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Cutaneous Fistula; Double-Blind Method; Female; Fistula; Humans; Lar | 2015 |
Quality of life in laryngopharyngeal reflux patients.
Topics: Adult; Enzyme Inhibitors; Female; Follow-Up Studies; Gastroesophageal Reflux; Humans; Laryngeal Dise | 2007 |
11 other studies available for omeprazole and Diseases of Pharynx
| Article | Year |
|---|---|
Effects of helicobacter pylori eradication on chronic nonspecific pharyngeal symptoms.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Chronic Disease; Cohort | 2008 |
[Typical and atypical symptoms of laryngopharyngeal reflux disease].
Topics: Adult; Anti-Ulcer Agents; Diagnosis, Differential; Esophagus; Female; Gastroesophageal Reflux; Heart | 2002 |
Pachydermia is not diagnostic of active laryngopharyngeal reflux disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid | 2004 |
Validation of a quality-of-life instrument for laryngopharyngeal reflux.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Humans; Laryngeal Diseases; Middle Aged; Omeprazo | 2005 |
Can heterotopic gastric mucosa present as globus pharyngeus?
Topics: Anti-Ulcer Agents; Choristoma; Conversion Disorder; Diagnosis, Differential; Esophageal Diseases; Fe | 2006 |
Role of gastroesophageal reflux disease in patients with cervical symptoms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barium Sulfate; Biopsy; Cineradiograp | 1995 |
Empiric trial of high-dose omeprazole in patients with posterior laryngitis: a prospective study.
Topics: Anti-Ulcer Agents; Cough; Deglutition Disorders; Female; Follow-Up Studies; Gastroesophageal Reflux; | 1997 |
Presumed laryngo-pharyngeal reflux: investigate or treat?
Topics: Anti-Ulcer Agents; Clinical Protocols; Diagnosis, Differential; Female; Gastroesophageal Reflux; Hum | 2000 |
Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Deglutition Disorders; Fema | 2000 |
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie | 2001 |
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie | 2001 |
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie | 2001 |
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie | 2001 |
Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; | 2001 |