Page last updated: 2024-11-01

omeprazole and Dementia

omeprazole has been researched along with Dementia in 5 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"To investigate the impact of MHRA DHPCs on prescribing practice in the secondary-care setting, looking specifically at a drug-drug interaction-the concomitant use of clopidogrel and proton pump inhibitors (PPIs) [as omeprazole]-and a drug-disease contraindication-the use of conventional (typical) antipsychotics in dementia."3.79The impact of direct healthcare professional communication on prescribing practice in the UK hospital setting: an interrupted time series analysis. ( Coleman, JJ; Dhami, A; Hodson, J; McIlroy, G; Thomas, SK, 2013)
"Pantoprazole was the most frequently used PPI agent."1.91Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany. ( Ahn, N; Baumeister, SE; Gerlach, R; Günter, A; Güntner, F; Linseisen, J; Meisinger, C; Nolde, M; Rückert-Eheberg, IM; Tauscher, M; Wawro, N, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's4 (80.00)2.80

Authors

AuthorsStudies
Weiss, A2
Gingold-Belfer, R2
Boltin, D1
Beloosesky, Y1
Koren-Morag, N1
Meyerovitch, J1
Sharon, E1
Schmilovitz-Weiss, H2
Du, J1
Lai, Y1
Zhang, L1
Ahn, N1
Wawro, N1
Baumeister, SE1
Nolde, M1
Gerlach, R1
Tauscher, M1
Günter, A1
Güntner, F1
Rückert-Eheberg, IM1
Meisinger, C1
Linseisen, J1
Thomas, SK1
Hodson, J1
McIlroy, G1
Dhami, A1
Coleman, JJ1

Other Studies

5 other studies available for omeprazole and Dementia

ArticleYear
Chronic omeprazole use in the elderly is associated with decreased risk of dementia and cognitive decline.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2022, Volume: 54, Issue:5

    Topics: Aged; Cognitive Dysfunction; Dementia; Humans; Omeprazole; Proton Pump Inhibitors; Retrospective Stu

2022
Chronic omeprazole use in the elderly: Is it related to the risk of dementia and cognitive decline?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2022, Volume: 54, Issue:9

    Topics: Aged; Cognitive Dysfunction; Dementia; Humans; Omeprazole

2022
Author's Reply: "Chronic omeprazole use in the elderly: Is it related to the risk of dementia and cognitive decline?"
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2022, Volume: 54, Issue:9

    Topics: Aged; Cognitive Dysfunction; Dementia; Humans; Omeprazole

2022
Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany.
    Drugs & aging, 2023, Volume: 40, Issue:7

    Topics: Cognitive Dysfunction; Dementia; Humans; Omeprazole; Pantoprazole; Proton Pump Inhibitors

2023
The impact of direct healthcare professional communication on prescribing practice in the UK hospital setting: an interrupted time series analysis.
    Drug safety, 2013, Volume: 36, Issue:7

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Clopidogrel; Communication; Dementia;

2013