omeprazole has been researched along with Coronary Disease in 10 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To estimate the effect of double omeprazole dose on the course of angina pectoris and treadmill stress test in patients with coronary artery disease (CAD), using double-blind, crossover randomised, placebo-controlled study design." | 9.13 | The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial. ( Budzyński, J; Fabisiak, J; Kłopocka, M; Majer, M; Pulkowski, G; Suppan, K; Swiatkowski, M, 2008) |
| "To estimate the effect of double omeprazole dose on the course of angina pectoris and treadmill stress test in patients with coronary artery disease (CAD), using double-blind, crossover randomised, placebo-controlled study design." | 5.13 | The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial. ( Budzyński, J; Fabisiak, J; Kłopocka, M; Majer, M; Pulkowski, G; Suppan, K; Swiatkowski, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Munthe, DHB | 1 |
| Sargo, SS | 1 |
| Yogiarto, M | 1 |
| Cai, J | 1 |
| Wu, Q | 1 |
| Fan, L | 1 |
| Liu, CF | 1 |
| Wang, ZG | 1 |
| Sun, J | 1 |
| Giral, A | 1 |
| Ozdogan, O | 1 |
| Celikel, CA | 1 |
| Tozun, N | 1 |
| Ulusoy, NB | 1 |
| Kalayci, C | 1 |
| Elizalde, JI | 1 |
| Pérez-Pujol, S | 1 |
| Heras, M | 1 |
| Sionis, A | 1 |
| Casanovas, N | 1 |
| Martorell, T | 1 |
| Lozano, M | 1 |
| González, J | 1 |
| Escolar, G | 1 |
| Sanz, G | 1 |
| Piqué, JM | 1 |
| Gilard, M | 1 |
| Arnaud, B | 1 |
| Le Gal, G | 1 |
| Abgrall, JF | 1 |
| Boschat, J | 1 |
| Budzyński, J | 1 |
| Kłopocka, M | 1 |
| Pulkowski, G | 1 |
| Suppan, K | 1 |
| Fabisiak, J | 1 |
| Majer, M | 1 |
| Swiatkowski, M | 1 |
| Thumshirn, M | 1 |
| Schweeger, I | 1 |
| Fitscha, P | 1 |
| Sinzinger, H | 1 |
| Koop, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clopidogrel and Proton Pump Inhibitors: A Propensity Score Adjusted Cohort Study to Examine a Possible Interaction: A CALIBER Study[NCT01231867] | 24,471 participants (Actual) | Observational | 2010-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for omeprazole and Coronary Disease
| Article | Year |
|---|---|
[Impact of different proton pump inhibitors on the antiplatelet activity of clopidogrel in combination with aspirin for patients undergoing coronary stent implantation].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Angioplasty, Balloon; Aspirin; Clopidogrel; Co | 2010 |
Effect of Helicobacter pylori eradication on anti-thrombotic dose aspirin-induced gastroduodenal mucosal injury.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer | 2004 |
Effects of Helicobacter pylori eradication on platelet activation and disease recurrence in patients with acute coronary syndromes.
Topics: Acute Disease; Amoxicillin; Antigens, CD; Coronary Disease; Female; Helicobacter Infections; Helicob | 2004 |
The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial.
Topics: Analysis of Variance; Angina Pectoris; Anti-Ulcer Agents; Chest Pain; Coronary Disease; Cross-Over S | 2008 |
6 other studies available for omeprazole and Coronary Disease
| Article | Year |
|---|---|
Antiaggregation effect of clopidogrel in coronary heart disease patients using omeprazole.
Topics: Adult; Anti-Ulcer Agents; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Omeprazo | 2020 |
[Proton pump inhibition: more than only reflux therapy].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Asthma; Chest Pain; Clopidogrel; Comorbi | 2008 |
Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin.
Topics: Aged; Angioplasty; Aryl Hydrocarbon Hydroxylases; Aspirin; Cell Adhesion Molecules; Clopidogrel; Cor | 2006 |
[A case from practice (316). Hiccups in grade I reflux esophagitis and hiatal hernia. Suspected coronary heart disease in NYHA II angina pectoris].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Chest Pain; Coronary Disease; Diagnosis, Differential; Eso | 1995 |
Successful eradication of Helicobacter pylori as determined by ((13))C-urea breath test does not alter fibrinogen and acute phase response markers.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute-Phase Reaction; Adult; Aged; Anti-Bacterial Agents; A | 2000 |
[Ulcer prevention in therapy with low-dose acetylsalicylic acid?].
Topics: Aspirin; Brain Ischemia; Coronary Disease; Drug Therapy, Combination; Histamine H2 Antagonists; Huma | 1991 |